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조성현,황정해,김은경,오병희,김창엽 한국의료QA학회 1996 한국의료질향상학회지 Vol.3 No.1
Background : Blood pressure is an important indicator in diagnosis and assessing treatment of a patient. Clinical staffs use blood pressure on the assumption that measured value is accurate and reliable. However, whether measured blood pressure is accurate has been rarely investigated in Korea. Objectives : The aims of this study are to evaluate clinical staffs' knowledge and technique as well as accuracy of sphygmomanometer. Also the program to improve the measurement is developed. Methods : Seventy-three registered nurses were asked nine multiple choice questions including Korotkoff sound, cuff size, and deflation rate. Simultaneously characteristics of nurses were examined age, working place, duration of employment and academic degree. A testing videotape(Standardizing Measurement Video-Tutored Course) was used for evaluating the accuracy of measurement. Testees were to read and record the 12 cases of blood pressure measurement, watching a falling mercury column and hearing Korotkoff sounds. After 10 minutes' education, they were again tested with the same cases. Additionally, 83 mercury sphygmomanometers were checked to find defects such as inaccurate calibration and zero setting, leaky bladder, etc. Results : For the knowledge testing correct response rate was 41.1%. They were the lowest in selecting the proper cuff size and Korotkoff sound. In examining accuracy of blood pressure with videotape, nurses had 67.7% correct response rate. The correct response rate was significantly improved by a session of education. About 23% of sphygmomanometers was without discemable defects. Conclusion : The knowledge and skill of clinical staffs along with the accuracy of equipment have to be improved. A properly designed education program would contribute to the accuracy improvement of blood pressure measurement. Also, more concerns should be given to the precision and maintenance of equipment.
진딧물의 경보페로몬인 (E)-β-Farnesene의 합성과 생물활성시험
강석구,정경운,이정운,고현관 성균관대학교 기초과학연구소 1986 論文集 Vol.37 No.1
(E)-β-Farnesene, the alarm pheromone of aphids was synthesized from nerolidol by reacting in a sealed tube at 150℃ for 24h with DMSO. Base(KOtBu/DMSO) catalized elimination of HCl from farnesyl chloride at 50℃ for 4h afforded (E)-β-farnesene as the major product. Farnesyl chloride was prepared from nerolidol or farnesol with SOCl_2 or HCl. Biological activity test of (E)-β-farnesene thus synthesized was conducted.
Alternative of Phosphate by Freeze- or Oven-Dried Winter Mushroom Powder in Beef Patty
Hyun Gyung Jeong,Doo Yeon Jung,Kyung Jo,Seonmin Lee,Yun-Sang Choi,Hae In Yong,Samooel Jung 한국축산식품학회 2021 한국축산식품학회지 Vol.41 No.3
This study investigated freeze- or oven-dried winter mushroom powder (FDP or ODP, respectively) as an alternative to phosphate in beef patties. The beef patties were prepared with four treatments: no addition of phosphate and winter mushroom (control), addition of 0.3% sodium pyrophosphate (BP), addition of 1% FDP (BFW), and addition of 1% ODP (BOW). The pH of FDP and ODP was 6.73, and 7.00, respectively. FDP and ODP contained phenolic compound at a level of 3.50 and 5.45 g gallic acid equivalent/kg, respectively. The cooking loss of beef patties was the highest in the control and lowest in BP (p<0.05). BFW had lower cooking loss than the control (p<0.05), and BOW showed similar cooking loss as that of the control (p>0.05). Inhibition of lipid oxidation was found in BP and BOW as compared with control (p<0.05). BFW was similar to the control in terms of the degree of lipid oxidation (p>0.05). BOW showed lower L* and higher a* values than those of the control, BP and BFW (p<0.05). Texture properties such as hardness, springiness, cohesiveness, gumminess, and chewiness were the highest in BP (p<0.05). A slight increase in hardness and springiness was observed in BOW compared to those of the control (p<0.05). The results showed that FDP and ODP did not exhibit all the properties of phosphate in beef patties. Therefore, FDP and ODP can be used for partial substitution of phosphate in beef patties.
곤륜(BL60) 자침 후 발생한 족부의 봉와직염 및 족관절 윤활막염: 증례 보고
도현정 ( Hyun Jeong Do ),이은주 ( Eun Ju Lee ),박경훈 ( Gyung Hun Park ),박윤령 ( Yun Leong Park ),서종철 ( Jong Cheol Seo ),김철홍 ( Cheol Hong Kim ),윤현민 ( Hyun Min Yoon ) 경락경혈학회 2021 Korean Journal of Acupuncture Vol.38 No.4
훈침 등 침 시술의 이상 반응은 대부분 경미하고 일시적인 경과를 보이므로 그 위험성을 간과하기 쉽다. 하지만 20만분의 1의 확률로 침 시술 이후 감염이나 신경계 손상 등의 심각한 합병증이 발생하며 이는 치명적인 경과로 진행하기도 한다. 따라서 시술후 이상반응이 발생할 시에는 예방적 차원의 적극적 처치를 고려하는 것이 합당할 것으로 사료된다. 본 증례 또한 자침 직후의 이상반응이 가벼운 동통으로 나타나며, 발생 당시 뚜렷한 피부증상을 확인하지 못하였으므로 그 위험성을 낮게 판단하여 진단 및 처치가 늦어진 사례로 볼 수 있다. 환자가 고령 혹은 만성 질환자로 염증을 발전시킬 수 있는 소인이 있는 경우 침첨이 피부를 자극하는 수준의 가벼운 자침을 시행하더라도 피부 상재균주에 의한 봉와직염 발생의 위험성이 높다. 따라서 반드시 시술 전 소독 등의 감염예방을 철저히 하고, 시술 후하지 및 족부에 발적이나 열감, 통증 등의 이상반응 발생 시 적극적인 양방 처치 또한 고려할 필요가 있다. 본 증례가 동료 임상의들의 주의를 환기시키는 데 도움이 되었으면 하는 바이다. The purpose of this study is to report a case diagnosed with cellulitis and ankle joint synovitis after acupuncture treatment. An 85-years old female suffering from low back pain was managed by acupuncture including BL60. After treatment, unintended ankle pain occurred. The pain was diagnosed with cellulitis and synovitis by MRI. The patient was transferred to the Western medical hospital, and ankle joint arthroscopic synovectomy was performed. It was difficult to find a clear relationship between acupuncture and ankle joint synovitis. But it would be reasonable to assume that cellulitis was associated with acupuncture needling and synovitis was followed. Serious adverse effects, such as septic arthritis, are rare, but need significant attention. For acupuncture treatment on the ankle, especially using BL60, the depth and manipulation should be carefully performed along with sterilization.
( Hyun Gyung Jang ),( Jin-sin Koh ),( Jeong Rang Park ),( Yongwhi Park ),( Young Hoon Jung ),( Choong Hwan Kwak ),( Jin-yong Hwang ),( Seok-jae Hwang ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1
Background:?Passive leg raising (PLR) increases preload and is known to increase pulmonary capillary wedge pressure (PCWP) in heart failure with preserved ejection fraction (HFpEF) patients. However correlation between PLR induced increase of PCWP and dynamic exercise induced increase of PCWP is not well established.?Methods:?Thirty nine patients with unexplained dyspnea and ejection fraction >50% underwent invasive exercise test. After resting right cardiac cath, supine cycle ergometer exercise with 10 watt increments in 3 minute from 20 watt was performed to maximum tolerated levels. PCWP was measured at resting supine position, before exercise with PLR and after 3 minutes of 20 watt exercise. Patients with normal resting PCWP<15 mmHg and exercise PCWP >25 mmHg were classified as early-HFpEF.?Results:?Among total of 39 patients (mean age 67 years, 28 women), 13 patients showed elevated resting PCWP of 16±4 mmHg and 26 patients had normal PCWP of 12±2 mmHg at rest. Twenty six patients with normal PCWP at rest were classified into early HFpEF (n=16, 32±4 mmHg after exercise vs 13±2 mmHg at rest) or noncardiac dyspnea (NCD, n=10, 20±3 mmHg after exercise vs 12±2 mmHg at rest). PLR increased PCWP in both early-HFpEF and NCD group but this was more evident in early-HFpEF than in NCD group (19±3 mmHg vs 15±3 mmHg, p=0.005). PLR induced PCWP was good correlation with exercise PCWP (R2=0.61, p<0.001). The optimal cutoff value for PLR-PCWP to detect early HFpEF was 17 mmHg (sensitivity, 0.69; specificity, 0.70), yielding an AUC of 0.81 (95% CI, 0.64 to 0.98). Positive predictive value of leg raising PCWP >17 mmHg for diagnosis of early HFpEF was 79% and negative predictive value was 58%.?Conclusions:?PLR test could be used for detecting early HFpEF with good accuracy in substitution for cycle ergometer exercise test.