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조성현,Quoc Hoang,Jeong Won Phee,김윤영,신현영,신정섭 한국분자세포생물학회 2007 Molecules and cells Vol.23 No.1
The moss Physcomitrella patens has two life cycles, filamentous protonema and leafy gametophore. A modified from of suppression subtractive hybridization (SSH), mirror orientation selection (MOS), was applied to screen genes differentially expressed in the P. patens protonema. Using reverse Northern blot analysis, differentially expressed clones were identified. The identified genes were involved mainly in metal binding and detoxification. One of these genes was an AP2 (APETALA2) domain-containing protein (PpACP1), which was highly up-regulated in the protonema. Alignment with other AP2/EREBPs (Ethylene Responsive Element Binding Proteins) revealed significant sequence homology of the deduced amino acid sequence in the AP2/EREBP DNA binding domain. Northern analysis under various stress conditions showed that PpACP1 was induced by ethephon, cadmium, copper, ABA, IAA, and cold. In addition, it was highly expressed in suspension-cultured protonema. We suggest that PpACP1 is involved in responses to metals, and that suspension culture enhance the expression of genes responding to metals.
曺成鉉 홍익대학교 산업기술연구소 2001 産業技術 Vol.11 No.-
Recently multimedia traffics have increased rapidly, and the data processing capacity of routers also has increased. Furthermore, various protocols have appeared since applications require different services. Therefore, open programmable interfaces are necessary to support various services dynamically. In this paper, we studied the open programmable interface that is applicable to IP routers, and designed an open programmable interface for IP routers to support the differentiated service.
趙成鉉 홍익대학교 산업기술연구소 2002 産業技術 Vol.12 No.-
The rapid proliferation of the Internet and the cost-effective growth of its key enabling technologies are revolutionizing information technology and creating unprecedented opportunities for developing large-scale distributed applications. At the same time, there is a growing concern over the security of Web-based applications. Although there has been phenomenal growth of Web-based applications on the Internet, access control issues related to Web security have largely been neglected. Several models have been proposed to address the access control requirements of distributed applications. Traditional access control models are broadly categorized as discretionary access control (DAC) and mandatory access control (MAC) models. Recently the role-based access control (RBAC) models have been proposed to address the security requirements of a wider range of applications. We present a comparative assessment of these models in terms of supporting Web-based applications. The RBAC models are expected to provide a viable framework for addressing a wide range of security requirements for large enterprises. We show how secure cookies support RBAC on the Web, and show that secure cookies can provide three types of security services: authentication, integrity, and confidentiality.
曺成鉉 홍익대학교 산업기술연구소 2003 産業技術 Vol.13 No.-
As the Internet becomes popular, online game industries are expanding rapidly, especially in Korea. The advance of technologies of real-time computer graphics and computer hardware makes it possible to realize 3D games, and 3D online games have become a major stream in the game industry in Korea. However, many game developing companies wants to make 3D games, but it is very difficult to find experts who can fulfill their tasks. Moreover, none of advanced companies wants to share their technologies with other companies. Now it is necessary to develop 3D game engines and distribute them to game developing companies at a low price so that they can focus on the game contents rather than game technologies. Online 3D engines consist of rendering engines, animation engines, sound engines, and server engines. In this paper, we study only server engines, that is, important issues in developing online 3D servers, and problems that may occur in distributed multiserver environments. We focus on scalibility issues because it is very critical for online 3D servers to accomodate as many users as possible.
입원환자 간호관리료 차등제 도입이후 간호사 확보수준의 변화
조성현,전경자,김윤미,박보현 대한간호학회 간호행정학회 2008 간호행정학회지 Vol.14 No.2
Purpose: To examine the changes in nurse staffing in hospitals after implementing the policy of differentiating inpatient nursing fees by staffing grades. Method: The study sample included 43 tertiary hospitals, 185 general hospitals, and 282 non-general hospitals that were operating in both 1999 and 2008. Nurse staffing grade was categorized from Grade 1 (highest) to 6 (lowest) in 1999 or Grade 7 in 2008, based on the nurse-to-bed ratio. Results: Tertiary hospitals at Grade 3 and Grade 4 accounted for 49% and 35%, respectively, in 2008, whereas 63% were Grade 6 in 1999. General hospitals at Grade 6 decreased from 87% to 48%. In non-general hospitals, little change was found in the staffing distribution, in that 92% still remained in Grade 6 or 7 in 2008. Forty tertiary hospitals (93%) and 45% of general hospitals improved their staffing grades, while only 7% of non-general hospitals did. Greater likelihood of improvement in staffing grades was found in general hospitals located in metropolitan areas or having 250 or more beds. Conclusion: Elaboration of the financial incentive system is needed to increase the policy impact on staffing improvement.
소아에서 치아 우식 경험과 새로운 치아 우식 활성 비색 검사
조성현,이효설,최병재,김백일,김성오,최형준 大韓小兒齒科學會 2015 大韓小兒齒科學會誌 Vol.42 No.1
A new colorimetric test (Cariview ) using a new type of pH indicator can reflect the acidogenic potential ofplaque bacteria. The objective of this study was to evaluate the correlation between Cariview and the cariesexperience (measured through the dmft index) of children, and to compare Cariview with Dentocult SM . Having obtained informed consent, 135 children less than 6 years old participated in the study. We examinedtheir dmft index, and performed two caries activity tests (Cariview and Dentocult SM ) according to the manufacturers’instructions. In the results, Cariview showed a moderate correlation with the dmft index (r = 0.43, p < 0.01). Cariview showed a sensitivity of 68.8%, a specificity of 69.2%, and an area under curve of 0.686 in the ROC curve analysis. Cariview had a significant correlation with the children’s caries experience and had a slightly better explanatoryability than Dentocult SM . Furthermore, Cariview was convenient and easy to use on uncooperative children, and also had an educationaleffect with its visual colors. It is suggested that Cariview could be used clinically to identify the childrensusceptible to develop caries and to establish a preventive strategy 새로운 우식 활성 비색 검사인 Cariview 는 새로운 pH 지시약을 사용해서 치태 세균의 산 생산 능력을 더 잘 반영할 수있다. 본 연구는 소아에서 Cariview 와 치아 우식 경험(dmft index)과의 상관성을 평가하고, Cariview 를 Dentocult SM 과 비교할 목적으로 수행되었다. 만5세 이하 135명의 소아를 대상으로 dmft를 기록했으며, Cariview 와 Dentocult SM 두 가지 우식 활성 검사를 제조사 지시에 따라 시행하였다. 그 결과, Cariview 는 소아의 치아 우식 경험과 중등도의 상관관계를 보였다(r = 0.43, p < 0.01). 치아 우식증 예측에있어 Cariview 는 민감도 68.8%, 특이도 69.2%, ROC 곡선 분석의 곡선하면적(AUC) 0.686으로 Dentocult SM 에 비해 양호한 수치를 보였다. Cariview 는 비협조적인 어린이에게도 시행이 쉽고 편리하며 시각적인 색상으로 나타나 구강위생교육 도구로서 가치가있다.