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유리체강 내 트리암시놀론 주사 후 황반 허혈이 합병된 양측 광범위 매독 점상 내망막염
조성현,김소희,이승민,변익수,이지은,권한조 대한안과학회 2022 대한안과학회지 Vol.63 No.12
목적: 유리체강 내 트리암시놀론 주입 후 광범위한 점상 내망막염이 발병하여 안매독으로 진단 후 치료하였으나 황반허혈이 합병된1예를 다중 망막 영상 소견과 함께 보고하고자 한다. 증례요약: 69세 남자 환자가 첫 유리체강 내 트리암시놀론 주사 후 양안 시력이 안전수지로 저하되어 의뢰되었다. 안저검사에서 망막표층내 노란색 점상 침착물이 광범위하게 출현하였고 세동맥염과 유리체염이 동반되었다. 침착물 주위는 빛간섭단층혈관조영에서표층 및 심층 망막의 혈관밀도 감소와 형광안저혈관조영에서 국소 저형광으로 관찰되었다. 혈청매독검사에서 양성으로 판정되어 안매독에 동반한 점상 내망막염으로 진단하였다. 2주간 수용성 페니실린을 매일 2천 4백만 단위로 정주 치료 후 6개월 뒤 점상 내망막염 및 유리체염은 소실되었고 양안 교정시력은 20/100으로 호전되었다. 하지만 폐쇄성 혈관염으로 인한 모세혈관 비관류는 회복되지않아 황반허혈이 지속되었다. 결론: 광범위한 매독 점상 내망막염이 유리체강 내 스테로이드 주사 후 발생할 수 있고 폐쇄성 혈관염으로 인한 내망막허혈로 시력저하가 지속될 수 있다. 첫 안구 내 스테로이드 주사 치료가 계획된 환자는 매독 선별검사를 추천한다. Purpose: To report a case of extensive syphilitic punctate inner retinitis (SPIR) triggering bilateral macular ischemia after intravitreal triamcinolone injections, and the multimodal retinal imaging findings. Case summary: A 69-year-old male patient with nonproliferative diabetic retinopathy was transferred to our hospital because of bilateral visual deterioration (to counting fingers) after the first intravitreal triamcinolone injection. Fundus examination revealed numerous yellow punctate precipitates in the superficial retinae, retinal arteriolitis, and vitritis. The punctate lesions and surrounding retinal regions showed decreased vascular density on optical coherence tomography angiography, and focal hypofluorescence on fluorescein angiography. The patient was positive for all of the Venereal Disease Research Laboratory test, the fluorescent treponemal antibody-absorption test, and Treponema pallidum hemagglutination; we diagnosed bilateral SPIR. After treatment with aqueous crystalline penicillin solutions (24 million units per day for 14 days), the punctate lesions reduced but arteriolitis progressed to obliterative vasculitis. After 6 months, the bilateral SPIR and vitritis resolved, and the bilateral visual acuity improved to 20/100. However, inner retinal and macular ischemia persisted because of capillary nonperfusion attributable to obliterative vasculitis. Conclusions: Extensive SPIR can develop after an initial intravitreal steroid injection; the inner retinal ischemia and visual loss may persist after treatment because obliterative vasculitis develops. Therefore, patients scheduled for intravitreal steroid injections should be screened for syphilis infection.
기계학습을 이용한 Joint Torque Sensor 기반의 충돌 감지 알고리즘 비교 연구
조성현,권우경 한국로봇학회 2020 로봇학회 논문지 Vol.15 No.2
This paper studied the collision detection of robot manipulators for safe collaboration in human-robot interaction. Based on sensor-based collision detection, external torque is detached from subtracting robot dynamics. To detect collision using joint torque sensor data, a comparative study was conducted using data-based machine learning algorithm. Data was collected from the actual 3 degree-of-freedom (DOF) robot manipulator, and the data was labeled by threshold and handwork. Using support vector machine (SVM), decision tree and k-nearest neighbors KNN method, we derive the optimal parameters of each algorithm and compare the collision classification performance. The simulation results are analyzed for each method, and we confirmed that by an optimal collision status detection model with high prediction accuracy.
소아에서 치아 우식 경험과 새로운 치아 우식 활성 비색 검사
조성현,이효설,최병재,김백일,김성오,최형준 大韓小兒齒科學會 2015 大韓小兒齒科學會誌 Vol.42 No.1
A new colorimetric test (Cariview ) using a new type of pH indicator can reflect the acidogenic potential ofplaque bacteria. The objective of this study was to evaluate the correlation between Cariview and the cariesexperience (measured through the dmft index) of children, and to compare Cariview with Dentocult SM . Having obtained informed consent, 135 children less than 6 years old participated in the study. We examinedtheir dmft index, and performed two caries activity tests (Cariview and Dentocult SM ) according to the manufacturers’instructions. In the results, Cariview showed a moderate correlation with the dmft index (r = 0.43, p < 0.01). Cariview showed a sensitivity of 68.8%, a specificity of 69.2%, and an area under curve of 0.686 in the ROC curve analysis. Cariview had a significant correlation with the children’s caries experience and had a slightly better explanatoryability than Dentocult SM . Furthermore, Cariview was convenient and easy to use on uncooperative children, and also had an educationaleffect with its visual colors. It is suggested that Cariview could be used clinically to identify the childrensusceptible to develop caries and to establish a preventive strategy 새로운 우식 활성 비색 검사인 Cariview 는 새로운 pH 지시약을 사용해서 치태 세균의 산 생산 능력을 더 잘 반영할 수있다. 본 연구는 소아에서 Cariview 와 치아 우식 경험(dmft index)과의 상관성을 평가하고, Cariview 를 Dentocult SM 과 비교할 목적으로 수행되었다. 만5세 이하 135명의 소아를 대상으로 dmft를 기록했으며, Cariview 와 Dentocult SM 두 가지 우식 활성 검사를 제조사 지시에 따라 시행하였다. 그 결과, Cariview 는 소아의 치아 우식 경험과 중등도의 상관관계를 보였다(r = 0.43, p < 0.01). 치아 우식증 예측에있어 Cariview 는 민감도 68.8%, 특이도 69.2%, ROC 곡선 분석의 곡선하면적(AUC) 0.686으로 Dentocult SM 에 비해 양호한 수치를 보였다. Cariview 는 비협조적인 어린이에게도 시행이 쉽고 편리하며 시각적인 색상으로 나타나 구강위생교육 도구로서 가치가있다.
입원환자 간호관리료 차등제 도입이후 간호사 확보수준의 변화
조성현,전경자,김윤미,박보현 대한간호학회 간호행정학회 2008 간호행정학회지 Vol.14 No.2
Purpose: To examine the changes in nurse staffing in hospitals after implementing the policy of differentiating inpatient nursing fees by staffing grades. Method: The study sample included 43 tertiary hospitals, 185 general hospitals, and 282 non-general hospitals that were operating in both 1999 and 2008. Nurse staffing grade was categorized from Grade 1 (highest) to 6 (lowest) in 1999 or Grade 7 in 2008, based on the nurse-to-bed ratio. Results: Tertiary hospitals at Grade 3 and Grade 4 accounted for 49% and 35%, respectively, in 2008, whereas 63% were Grade 6 in 1999. General hospitals at Grade 6 decreased from 87% to 48%. In non-general hospitals, little change was found in the staffing distribution, in that 92% still remained in Grade 6 or 7 in 2008. Forty tertiary hospitals (93%) and 45% of general hospitals improved their staffing grades, while only 7% of non-general hospitals did. Greater likelihood of improvement in staffing grades was found in general hospitals located in metropolitan areas or having 250 or more beds. Conclusion: Elaboration of the financial incentive system is needed to increase the policy impact on staffing improvement.