瓦松의 알콜 抽出物이 家兎의 腎機能에 미치는 影響

成惠淑,金光鎭 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.1

Orostachys malacophyllus F. has been applied in Chinese medicine as well as in folk remedy. Its chemical composition and pharmacological actions have not reported yet. But, sometimes, it was used in treatment for the stomach or lung cancer. This study was attempted to investigate the effects of the water fraction separated from alcohol extract of the plant on the renal functions of rabbits. After cannulation of carotid artery, jugular vein and ureters were prepared for the recording of blood pressure, the infusion of the water extract(0.005%) or the hypotonic saline(0.45%), and the collection of the urine, respectively. The hypotonic saline was infused to hydrate the rabbits, and the mixed solution of hypotonic saline, PAH, and inulin was infused to measure the glomerular filtration rate(GFR) and renal plasma flow (RPF). After the hydration, the changes of urine volume were obsereved during the infusion of the water fraction for 1 hour, and during the infusion of hypotonic saline for 80min. And the concentration of PAH or inulin in the urine and blood was measured by the method of Smith and the method of Schreiner, electrolyte concentration by flamephotometer, and the osmolar conentration by osmometer, respectively. The results were summarized as follows: 1. Urine volume, GFR, and RPF were decreased significantly by the infusion of water fraction, and thery were not recovered to control values after the exchange to hypotonic saline. 2. Filtration fraction was increased by water fraction. 3. Water fraction decreased the plasma clearances of electrolytes and the osmolar substances, and increased the negative free water clearance. 4. Water fraction increased the reabsorptive rate(%)of potassium, and decreased the excretory amount of Na or K. And it was decreased the ratio of Na/K excretion. From the above results, it was suggested that water fraction has the antidiuretic effect and its mechanism is primarily caused by the change of the renal hemodynamics.

회맹장 및 대장을 침범한 장 결핵에 있어서 바륨을 이용한 방사선 이중조영촬영 소견에 대한 연구

진용현,전혜정,이용근,강철호,조성범,김윤환,박철민,차상훈,김일영,이혜경 건국대학교 의과학연구소 2002 건국의과학학술지 Vol.12 No.-

To determine the characteristic double contrast barium enema findings of ileo-cecal and colonic tuberculosis and to make differential diagnosis from other bowel inflammatory disease. Sixty-seven patients confirmed as ileo-cecal and/or colonic-tuberculosis in six hospitals were evaluated retrospectively. The diagnosis was proven by endoscopic biopsy, surgery, and clinical follow up. Nine of 67 patients were excluded because radiologic findings were normal though endocopic biopsy examinations resulted in tuberculosis. Histopathological diagnosis were madein 58 cases as follows: endoscopic biopsy(n=29), operation(n=12), follow up examination(n=14), tissue culture(n=1), laparoscopic biopsy(n=2). There were 30 men and 28 females. The mean age were 36 yrs(range:16-67), 34 patients were in the second and third decade. The distribution of lesions, morphological characteristics, mucosal changes, ulcer shape and depth, associated with other tuberculous lesion, multiplicity were retrospectively analyzed in the findngs of double contrast barim enema. The commonest clinical symptoms were abdominal pain(n=35, 60%) and diarrhea(n=18, 31%). The chest radiography revealed association of pulmonary tuberculosis in 39 cases. Tuberculous lesions of other organs except chest were present in five cases. Double contrast barium enema findings showed a thickening and irregularity of intestinal mucosal fold(n=29, 50%), bowel contraction and/or shortening(n=26, 45%). There were small, nodular, superficial ulcers in the case of ulcer depth less than 2 mm in the depth. As many as 39 cases(67%) in this series had two or more lesions in the intestinal tuberculosis. The involved segment revealed symmetrical feature(n=21, 36%). Inflammatory pseudopolypoid lesions were noted in 30 cases(52%). The ileo-cecal region was involved in 38 cases(66%). The ascending colon(n=25, 43%) was the second commonest site with or without contiguous cecal involvement. Lesions in terminal ileum, ileo-cecal valve, transverse colon, descending colon and appendix were seen in 19, 18, 18, 12 and seven cases, respectively. Among 18 cases of ileo-cecal valve lesions, there were incompetency in nine cases(16%) and wide gapping in four cases(7%). In 14 cases, tuberculous enterocolitis was diagnosed by clinical follow-up and double contrast barium enema study. 12 out of 14 cases, the findings of double contrast barium enema of tuberculous enterocolitis were normalized after anti-tuberculous medication. However, two cases showed more aggravated state than before due to inappropriate treatment. Double contrast barium enema plays an important role in the diagnosis of tuberculous enterocolitis, determines the type, site and extent of the involvement and helps in treatment guide by using sequential studies.

유산균(L.lactis CBT-8)및 발효 추출물의 Helicobacter pylori 억제 능력

진춘조,박형석,이혜운,김성렬,강동구,이준상,이재동,왕준호 건국대학교 의과학연구소 2002 건국의과학학술지 Vol.12 No.-

Helicobacter pylori infection was the cause of chronic gastritis, duodenal ulcer and gastric MALT lymphoma. The eradication rates of H. pylori using antibiotics are around 80%. Lactobacilli have been demonstrated to have in vivo and in vitro inhibitory effects on H. pylori infection. We aimed to evaluate the inhibitory effect of L. lactis CBT-8 and its extract on H. pylori in human stomach. Thirty-five H. pylori-infected volunteers(30-49 yr)were randomized into two groups which were treated with L. lactis CBT-8 and its extract(Group A n=17) or milk containing L. lactis CBT-8(Group B, n=18). They underwent 13C-urea breath tests before and after treatment. The DOB30 of group A(n=14) was decreased 41.0% after treatment(26.0±4.9 before, 15.3±2.1 after treatment)(p<0.05). the DOB30 of group B(n=13) was decreased 22.3% after treatment(22.0±2.2 before, 17.1±1.7 after treatment)(p<0.05). In conclusion, L. lactis CBT-8 was effective in suppressing H. pylori infection in human stomach.

[논문]자연신체활동 프로그램의 실태 및 인식 조사

진성욱,황해익 부산대학교 교육연구소 2011 교육혁신연구 Vol.21 No.2

본 연구에서는 교사-유아 간 애착안정성 정도에 따라 유아의 스트레스 정도 및 유아의 스트레스 대처행동에 어떠한 차이가 있는지 알아보고자 하였다. 연구 문제에 따른 연구 결과는 다음과 같다. 첫째, 교사-유아 간 애착안정성 정도에 따른 유아의 스트레스 정도에는 통계상 유의미한 차이가 없었고, 유아 스트레스 하위 영역인 교사, 또래, 학습 환경에서도 통계상 유의한 차이가 없는 것으로 나타났다. 다만 학습 활동영역에서 교사-유아 애착안정성이 낮은 유아 집단이 높은 집단보다 스트레스를 더 많이 받는 것으로 나타났다. 이러한 결과는 교사-유아 애착안정성 정도에 따라 교사, 또래,학습 환경 요인과 관련된 유아 스트레스에 차이가 없으며, 교사-유아 애착안정성이 높을수록 유아가 학습활동 요인과 관련된 스트레스를 덜 받는다는 것을 알 수 있다. 둘째, 교사-유아 간 애착안정성 정도에 따른 유아의 능동적, 수동적, 신비적 스트레스 대처행동 양식에서 통계상 유의한 차이가 나타났다. 교사-유아 간 애착안정성 정도가 높은 집단이 능동적 대처를 더 많이 하고, 교사-유아 간 애착안정성 정도가 낮은 집단이 수동적 대처와 신비적 대처를 비교적 더 많이 한다는 것을 알 수 있다. Due to lack of systemic program regarding physical activity in children, the study is to identify the constitution and development of the Natural Physical Activity Program by offering environmentally friendly elements such as wind, sun, mountain, sea, river, tree, flower, field for children. We expect children to learn the relation with nature, respect for life, understanding and love, importance of working together, and etc. The research questions for the purpose of this study are as followed: First, this study is going to identify the overall awareness and its needs of the Natural Physical Activity Program among preschool teachers. Second, we will look over how we can develop such program for preschool teachers. And a direction proposal on Natural Physical Activity Program. About 250 preschool teachers resided in Busan and Gyug-nam province were urged to participate in a research questioning their awareness and needs of the program. Among 250 preschool teachers, we choose 20 of them to interview about the goal, plan and development direction of the program. The result of the study is following as: First, most of the preschool teachers have a positive view on the Natural Physical Activity Program, and they agree that the program is highly needed to use. However, it is urge that overall education environment need to be improved to achieve its goal of the program. Second, the interview on the development direction is categorized as need, development direction, teaching method, evaluation method, activity, problem, improvement, solution, and etc. and, Third, the contents of the program include environmentally friendly elements such as wind, sun, mountain, river, sand, tree, flower, field to induce children’s interest and whole-person education. The contents of the program are expected to deliver hands-on experience for children. And also, the program includes physical activity using a nature object. Based on the potential problems we identified, a next study is expected to deal with following points. First, more empirical research is needed to prove the effectiveness of the program in a broad way by proposing a program that can be applicable at child-education center. Second, the study developed contents to make children feel enjoyable about nature. Unfortunately, in-depth research and development of such program is not sufficient. In this respect, more continuous research on Natural Physical Activity Program is required and need to be widely established.

Ni(111) 고체 표면에서 CO₂흡착과 해리 반응에 관한 이론적 연구

최상준,강혜진 인제대학교 1999 仁濟論叢 Vol.14 No.3

We have calculated CO2 adsorption and dissociation on a Ni(111) surface using the ASED-MO theory. We have found that the binding energy is strongest at di-σ(1) site and weakest at π -site. The binding energy on the next-favored 1-fold site is found to be somewhat less. For the dissociation of CO2, the OCO(1) angle is 145.7˚ on the Ni(111) surface. The activation energy is 0.56 eV in Ni(111) surface.

Ni(111) 고체표면에서 CO₂화학흡착에 관한 분자궤도론적연구

최상준,강혜진 인제대학교기초과학연구소 1999 자연과학 Vol.3 No.-

Ni(111)표면위의 CO₂흡착자리에 따른 흡착세기는 di-ο⑴, 1-fold, 3-fold,2-fold, π/μ,μ, 그리고 π-site순이다. di-ο⑴ 흡착자리에서는 <OCO가 148。인 찌그러진 CO₂분자구조를 가진다. 1-fold, 2-fold 및 3-fold의 경우는 CO₂분자중 산소의 한 끝이 고체표면과 결합하는 수직형태의 화학흡착이 일어남을 알았다. CO₂분자가 찌그럼짐은 2πu-obital과 섞임이 일어나기 때문이다. We calculated seven coordinated mode of binding site on Ni(111) surface; di-ο π,μ,π/μ, 1-fold, 2-fold, and 3-fold. Calculated binding energies are 2.31eV, 0.81eV, 1.50eV, 1.62eV, 2.27eV, 1.91eV, and 2.19eV, respectively. Then we have found that the binding energy is strongest at the di-ο(1) site. The adsorbed molecular CO2 of the di-ο(1) site on the Ni(111) surface is strong chemisorption and chemisorbed CO2 bends because of metal d-mixing with 2πu CO2 orbital.

광대역 종합정보통신망에서의 관리 요구사항 도출에 관한 연구

林海鎭,黃盛晧 三陟大學校 1998 論文集 Vol.31 No.1

In parallel with rapid advances and increased reliance on telecommunication services, network technologies continue to evolve. In addition, the advanced switching technologies required for ATM technology and switched multimegabit digital service(SMDS) are now being deployed. Considering the rapid deployment of new services and technologies, escalating competive pressures, and the broadening demands of customers, service providers face an immediate and pressing need to streamline, simplify, and automate network management operations. This research provides the first step in the requirements process for a new type o network operations capability. The logical model of this research describes a set of functions that could be assigned to either physical standalone components, operations systems, or network elements. This research should help facilitate consistency in the way the operations for different new technologies are specified.

제 2형 당뇨병 환자에서 대사증후군의 유병률 및 관련요인의 특징

박철진,박거운,박일구,신지혜,김진화,배학연,김상용 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.3

Background: People with insulin resistance has a higher risk of developing cardiovascular disease. This leads to the importance in diagnosing metabolic syndrome. The incidence of metabolic syndrome has increased significantly in korea because of an increased population of obese people and also the incidence of DM. There have been many studies done on the incidence of metabolic syndrome in the general population. Therefore, the authors have designed this study to identify the incidence of metabolic syndrome in patients with type 2 DM and also the associated characteristics in that population. Methods: The study included 169 adults over the age of 20 (84 males and 85 females) admitted to the endocrinology department of Chosun University between Jan, 1st 2005 and May, 31st 2006. Out of the people diagnosed with type 2 DM people were excluded when any of the physical measurements (height, weight, blood pressure, abdominal circumference) and blood measurements (TG, HDL-cholesterol, fasting blood sugar) were insufficient and when the patient was taking any drugs other than anti-hy-pertensive agents and oral anti-diabetic agents. Obesity and the other risk factors were defined by the Asian-Pacific guideline and 2001 ATP III of NCEP, respectively. Result: The each prevalence according to the metabolic syndrome criteria of the type 2 DM patients showed low HDL cholesterolemia with the highest incidence of 57.4% followed by hypertng1yceridemia(52.0%), obesity(40.9%) and hypertension(33.0%). The each incidence of diagnostic criteria in metabolic syndrome according to sex was different, In males, hypertriglyceridemia was the highest with the incidence of 57.7% followed by low HDL-cho1estero1emia(49.5%), obesity(40.9%) and hypertension (30.0%). In women, the incidence were low HDL-cho1estero1emia(64.8%), hyperthg1yceridemia(47.6%), obesity(45.0%) and hypertension(36.0%), in a descending order. The analysis between the diagnosis of metabolic syndrome in type 2 DM patients and the criteria showed that hyperthglyceridemia (correlative value 0.575) had the highest correlation followed by low HDL-cholesterolemia (correlative value 0.446), obesity (correlative value 0.350) and hypertension (correlative value 0.410). All the correlations were statistically significant with a p-value less than 0.01. Conclusions: Type 2 DM is a important factor of metabolic syndrome based on insulin resistance. The control of blood glucose with prevention and early diagnosis of the other factors related to metabolic syndrome in type 2 DM is important for preventing cardiovascular complications.

優先順位를 附與한 ATM 멀티캐스트 스위치의 呼處理 構造에 關한 硏究

황성호,오주현,임해진 三陟大學校 1999 論文集 Vol.32 No.1

An ATM multicast switch which can effectively accommodate diverse classes of traffic, is the core component of broadband ISDN. In this paper, we proposed a new call scheduling algorithm assigning priority according to the quality of service under the diverse traffic environment in multicast switch. The algorithm presented in this paper is using unfairness of switch structure, and delay-sensitive traffic may be given the high priority such that it can be transmitted as soon as possible. Also, we proposed a new hardware structure for the algorithm which can be constructed with combinational logic gates and it is beneficial for high-speed operation and VLSI implementation. The results of simulation for performance evaluation show that mean waiting time of delay-sensitive call is considerably reduced.

慶北地域에 自生하는 산달래의 倍數體分布와 核型分析

李誠恩,黃海鎭,吳仲烈,韓相政 대구효성가톨릭대학교 응용과학연구소 1997 응용과학연구논문집 Vol.5 No.-

산달래의 優良地方種 選拔과 育種을 위한 資料를 얻고자 慶北地域을 중심으로 倍數體分布와 核型을 調査한 結果를 要約하면 다음과 같다. 1)신달래는 染色體數 x=8을 基本으로 하고,2倍體 이외의 倍數體가 自生하고 있다는 事實이 알려져 왔으나 本 實驗에 供試한 慶北의 18個地域(行政區域上의 郡 單位)으로 부터의 蒐集種 가운데 15個地域의 蒐集種에서 4倍體(2n=4x=32)를,그리고 3個地域의 蒐集種에서 5倍體(2n=5x=40)를 볼수 있었고 2倍體는 볼수 없었다. 2)그리고 同一地域에 있어서도 4倍體와 5倍體가 混生하고 있음을 볼 때 이들은 自生地의 局部的인 生育環境에 따라 散發的으로 分布하고 있다고 생각되었다. 3)4培體와 5培體의 核型은 모두 中部,次中部및 次端部染色體로 이루어져 있고,매우 드물게 次中部染色體에서 附隨體를 볼수 있었다. 그리고 4培體의 核型은 20V+12J,23V+Vt+8J및 24V+8J의 3型으로,5培體의 核型은 25V+15J및 30V+10J의 2型으로 區分할 수 있었다. 4)18個地域의 蒐集種別로 본 가장 긴 染色體의 길이는 11.76(奉化)~23.47㎛(迎日)였고,가장 짧은 染色體의 길이는 4.24(英陽)~8.53㎛ (店村)였는데 迎日,英陽,鬱陵 및 盈德地域의 蒐集種에서는 각각 19.00㎛ 以上이 되는 特히 긴 1個의 染色體를 볼수 있어 注目되었다. This study was carried out to obtain the basic informations of a selection of superior geo-eco-type and breeding. The results in this study obtained were summarized as follows : 1. A basic number of chromosome of Allium grayi is x=8. Out of 18 localities of Allium grayi in this experiment examined, 15 localities have tetraploid, 3 localities have pentaploid, and diploid was not founded. 2. This result indicated that tetraploid and pentaploid plants are mixed in the same localization. It was supposed that it was distributed sporadically according to growth environment in each localization. 3. Karyotypes of tetraploid and pentaploid consisted of metacentric, submetacentric and subterminal chromosomes. They were investigated rarely satellite in sumbetacentric chromosome. Karyotypes of tetraploid were divided into three different types as 20V + 12J, 23V+V^t+8J and 24V+8J. Karyotypes of pentaploid were divided into two different types as 25V+15J and 30V+10J. 4. Out of 18 collected varieties, the length of the longest chromosomes were revealed 11.76 (Bonghwa)∼23.47㎛(Yungil), and the length of the shortest chromosomes were 4.24(Yungyang)∼8.53㎛(Jumchon). The collected varieties from Yungil, Yungyang, Ulleung and Yungduk have a long chromosome(〉19.00㎛) that has not detected other varieties.