간세포암환자에서 간동맥 화학 색전술 후 발생한 리피오돌에 의한 폐렴 1예

김소이,김유리,허현미,배서은,이명원,최윤정,김고흔,김태헌,유 권,문일환 이화여자대학교 의과대학 2009 EMJ (Ewha medical journal) Vol.32 No.2

Hepatocellular carcinoma(HCC)is one of common causes of cancer-related death in Korea where the majority of HCC patients were Hepaitc B virus(HBV)carriers and have cirrhosis. Transarterial chemoembolization(TACE)is commonly applied to the treatment of multinodular HCC in Korea and careful selection of candidate is important for the risk of various side effects. Besides common side effects as fever, nausea, abdominal pain and elevation of liver enzyme, TACE may predispose to hepatic failure, ischemic cholecystitis, pulmonary embolism, cerebral embolism and pneumonitis. In previous studies, some cases of pulmonary and cerebral embolism cases were reported but lipiodol pneumonitis after TACE was rarely reported. A 65-year-old woman with a multinodular HCC associated with HBV infection, was treated with TACE. Seven days after the procedure, nonspecific respiratory symptoms such as dyspnea and dry cough developed. Chest X-ray and chest computed tomography showed diffuse ground glass opacities in whole lung fields, suggestive of lipiodol pneumonitis. After several days of supportive care with steroid administration, radiologic abnormalities and subjective symptoms were much improved, considered that the disease was compatible with lipiodol pneumonitis.

임진왜란 시기에 작성된 <양호당이덕열언간>의 내용과 가치

김영 ( Kim Young ),장고은 ( Jang Go-eun ) 구결학회 2021 구결연구 Vol.46 No.-

이 연구는 임진왜란 시기에 작성된 <청풍김씨묘출토언간(양호당이덕열언간)> 13점의 편지 전문을 소개하고 그 내용적 특징과 의의를 밝혔다. 이 언간은 조선중기 주요 관직을 역임한 양호당(養浩堂) 이덕열(李德悅, 1534 1599)이 그의 부인 청풍김씨(1567 1637)에게 보낸 것이며 1점은 부인이 남편에게 쓴 편지이다. 편지의 발신 연대는 1590년대이다. 이 언간에는 조선 중기 주요 관직을 역임한 이덕열의 관직 생활이 담겨 있다. 그가 성주목사, 군기시 첨정, 개장도감 낭청, 명군(明軍)의 접반사로 재직할 당시의 상황, 즉 성주성 전투와 선조의 파천, 선릉과 정릉의 훼손과 복원 작업, 명군의 파병 등의 임진왜란의 역사적 사건이 포함되어 있다. 또한 전쟁으로 인한 피난과 경제적 어려움, 아들의 요절 등 그가 겪어야 했던 참상이 고스란히 담겨 있다. 언간과 함께 많은 물건이 오갔는데, 특히 ‘홑철릭, 초록철릭, 삼베철릭, 백단령, 베중치막, 적삼, 속것’ 등 다양한 복식 관련 어휘가 등장하며 전쟁 중에도 아내에게 직접 관복을 제작하여 받는 등 당시의 복식 생활의 모습을 담고 있다는 점도 특징적이다. <양호당이덕열언간>은 중세 국어와 근대 국어의 이행기적 면모를 보이는 소중한 국어사 자료이자 전쟁사, 생활사, 문화사 연구 자료로서도 매우 가치 있는 자료라 할 수 있다. This study introduced the full text of < Letters Excavated from Cheongpung Kim’s Tomb (Yanghodang Yi Deokyeol Eongan) > 13 letters, written in Korean during the Imjinwaeran period, and revealed the characteristics and significance. Most of the letters were written by Yanghodang (養浩堂) Yi Deokyeol (李德悅, 1534-1599), who served as a major government official during the mid-Joseon Period, and sent to his wife, Cheongpung Kim (1567-1637), and one letter was written by his wife to her husband. The originating date of these letters is in the 1590’s. These letters contain the life of Yi Deokyeol, who served as a major government official in the middle of the Joseon Dynasty. They show the historical events of Imjinwaeran, i.e. the battle of Seongjuseong and the leaving the Palace of the King Seonjo, destruction and restoration of Seolleung and Jeongneung, and the dispatch of the general of Ming army at the real time when he served as Seongju moksa (星州牧使), Gungisi Cheomjeong (軍器寺僉正), Gaejang Dogam nangcheong (改葬都監郎廳), and Jeopbansa (接伴使) of general of Ming army. They also contain the misery he had to suffer form, such as evacuating his family and experiencing poverty due to the war, and early death of his son. A lot of items came and went along with the letters, and in particular, various names of the things related to clothes appeared, such as single cheollik, green cheollik, hemp cheollik, white dallyeong, hemp jungchimak, jeoksam, sokkeok, etc. It is also characteristic that it contains the appearance of the clothing life such as making and receiving official uniforms from his wife during the war. Therefore, Yanghodang Yi deokyeol eongan is a valuable data for history of Korean language showing the transition between medieval and modern Korean, as well as research material on war history, life history, and cultural history.

유아교사의 완벽주의 군집유형에 따른 교사효능감과 소진

손고은(Go Eun Son),김연하(Yeon Ha Kim) 한국보육지원학회 2021 한국보육지원학회지 Vol.17 No.6

Objective: The purpose of this study was to classify early childhood educators’ perfectionism types and to identify differences in teacher self-efficacy and teachers burnout according to the types of perfectionism. Methods: The participants of this study were 309 teachers working at early childhood education centers in Seoul, Gyeonggi-do, Daejeon, Se-jong, Kim-Cheon, and Hong-Sung, South Korea. Early childhood educators were surveyed regarding perfectionism, teacher self-efficacy and teacher burnout. The collected data were analyzed using K-means cluster analyses and analysis of covariance. Results: Cluster analyses with self-oriented perfectionism and other-oriented perfectionism as cluster variables resulted in three types of perfectionism among early childhood educators; ‘self-other directed perfectionism(33.0%)’, ‘other directed perfectionism(35.0%)’ and ‘non perfectionism(32.0%)’. Educators with self-other directed perfectionism reported higher teacher self-efficacy and lower teacher burnout than educators with other directed perfectionism or with non perfectionism. Conclusion/Implications: Early childhood educators’ perfectionism may be a significant personality trait linked to quality of education and care in real education settings.

진해제 지놀타(Zipeprol 2HCl) 남용으로 유발된 기질성 정신장애 1례

김홍곤,박민철,노승호,김은숙 圓光大學校 醫科大學 神經精神科學敎室 1993 圓光精神醫學 Vol.9 No.2

We experienced a case of organic mental disorder following Zinolta(Zipeprol 2HCI) abuse for about a year. he showed neuropsychiatric symptoms such as vivid auditory and visual hallucinations, idea of reference, aggressive behaviors, and drowsy mental states. During the hospitalization, he was treated with benzodiazepines without any other specific treatment. He was improved and discharged with clear sensorium without any psychotic symptoms. Zipeprol Hydrochloride is a centrally acting cough suppressant. There have been reports of abuse and overdosage producing neurological symptoms. Although lacking in the comprehensive study explaining the pttersn of abuse, pharmacological effects and incidence of psychotic symptoms, this case suggests the need for evaluation of the potentially dangerous orgainc psychotic symptoms among the populations who are exposed.

Kiwi pectinesterase 저해제의 정제 및 특성

고은경,김명화,허원녕 목포대학교 자연자원개발연구소 1999 자연자원연구 Vol.2 No.-

Kiwi pectinesterase inhibitor(PEI)를 분리하기 위하여 CNBr-sepharose 4B에 orange pectinesterase(PE)를 공유결합으로 결합시켜 affinity chromatography용 수지를 제조하였다. 제조된 수지를 사용하여 PEI를 강력하게 선택적으로 결합시켜 pH 9.5의 높은 이온 강도를 갖는 용액으로 단일한 활성 peak로 용출·분리하였다. 분리된 kiwi PEI의 분자량은 12.5% SDS-PAGE 전기영동상에서 약 16.6 KDa 정도의 밀접한 이중 band로 나타났다. 분리된 PEI를 -25,℃ 5℃ 및 실온에서 30일 동안 보관·저장하였을 때 냉장, 냉동상태에서는 저해활성이 2주정도 경과시 25% 정도 감소하고 그 이후에는 큰 변화 없이 유지되었으나, 실온에서는 저해활성이 급격히 감소하여 저장 4주 정도에 거의 활성을 상실하였다. 이들의 활성특성을 조사해 본 결과 최적저해활성 pH는 7.5이고 최적저해반응 온도는 20℃였고, 70℃까지는 내열성을 지녔다. 또한 0.2M NaCl의 기질농도에서 최적저해 활성을 나타내었으며, kiwi PEI의 PE에 대한 저해작용은 noncompetitive inhibition인 것으로 나타났다. The resin for affinity chromatography was prepared to separate pectinesterase inhibitor(PEI) from ripened kiwi fruit(Actinidia chinensis) by CNBr-activated Sepharose 4B being covalently bound by orange petinesterse(PE). The affinity resin strongly and selectively bound PEI, which could be eluted in high yield as a single, homogeneous and sharp peak by pH 9.5 without loss of inhibitory activity. The separated PEI had maintained almost inhibitory activity at -25℃ and 5℃ during 30 days but lost it at room temperature in 4 weeks. The PEI possessed a molecular weight of 16.6 KDa, as estimated by 12.5% SDS-PAGE. The optimum pH, the optimum temperature, the thermostable range and NaCl concentration of substrate for PEI inhibitory activity appeared to be 7.5, 20℃, below 70℃ and 0.2 M respectively. The kind of inhibition on tomato pectinesterase was found to be noncompetitive, using citrus pectin as substrate.

흰쥐 치아 재식 후 치수 치유 양상의 조직학적 관찰

고은진,정한성,김의성,정일영,이승종 大韓齒科保存學會 2010 Restorative Dentistry & Endodontics Vol.35 No.4

본 연구의 목적은 흰 쥐 (rat) 를 이용하여 미성숙 단계의 치아를 발치 후 즉시 재식 하였을 때 나타나는 치수의 치유 양상을 조직학적으로 관찰하고자 하는 것이다. 생후 4주된 암컷 Sprague-Dawley 계 흰쥐의 상악 우측 제1대 구치를 발거 후 원래의 치조골와 내로 위치시켰다. 재식 후 3일째부터 국소적으로 치수 내 염증 소견이 관찰되었으나, 치근 부위에서는 이미 치수의 재혈관화 및 치유가 진행되고 있는 소견이 관찰되었다. 재식 후 5일째 부터는 odontoblast-like cell이 관찰되기 시작하였다. 삼차 상아질의 형성은 재식 후 1주째 부터 관찰되기 시작하였으며, 2주째부터는 확실히 관찰할 수 있었다. Odontoblast-like cell 및 삼차상아질 형성은 4주째 까지도 계속 관찰되었다. 재식 후 4주째에는 bone-like tissue 및 cementum-like tissue이 형성되었음을 관찰하였다. 본 실험을 통하여 흰 쥐 치아 재식시 석회화 과정은 초기에는 삼차상아질 침착에 의해서 진행되나, 시간이 경과하면서 점차 bone-like tissue 또는 cementum-like tissue가 차지하는 비율이 증가하는 것을 관찰하였다. The objective of this study was to observe the histology of dental pulp healing after tooth replantation in rats. The maxillary right first molars of 4-week-old rat were extracted. and then the teeth were repositioned in the original socket. At 3 days after replantation. there was localized inflammatory reaction. But, pulp revasculization and healing had already begun in the root area. At 5 days after replantation. odonto blast-like cells were observed. Tertiary dentin deposition was observed beneath the pulp-dentin border from 1 week after replantation. And tertiary dentin was increased at 2 weeks after replantation. The presence of odontoblast-like cells and the formation of tertiary dentin were continued to 4 weeks after replantation. At 4 weeks after replantation. the deposition of bone-like tissues and cementum-like tissues was observed. This results show that there is a possibility of pulp healing after tooth replantation in rats and the mineralization of tooth can progress. The mineralization of tooth after replantation was initially occurred by the deposition of tertiary dentin. but as time passed. the deposition of bone-like tissues and cementum-like tissues was begun and increased.

가토의 뇌동맥류 모형에서 모동맥 및 동맥류 협자에 따른 동맥류 내압의 변화 :기초 연구

김은영,송준혁,김명현,박향권,김성학,신규만,박동빈 대한신경외과학회 1999 Journal of Korean neurosurgical society Vol.28 No.4

産業體 特別學級 學生의 餘暇生活實態 및 餘暇意識에 관한 硏2究

고정자,김은주 東亞大學校 附設 生活科學硏究所 1995 생활과학연구 논문집 Vol.3 No.-

This study was attempted to analyse the situation of The Leisure Life of the students who attended the special night classes in attached-schools to the industries. The findings of this study were as followed: 1. living situation 1) Situation of school life. Their entering motives are that they have better self-respect and become capable men. majority of the students want to learn culture and thinking abilities. 2) Situation of job life majority of the students are working eight hours during weekdays and more tyannine hours during the vacation in their workshop. They show fatigue both mentally and physically by the monotonic working style from the sedentary work or rised work. 2. Actual condition of the leisure life majority of the students have little leisure time. Especially, the girl students has lesser than the boy students in their leisure time. Gererally they have less than three hours in weekdays and less than six hours in holidays. mojority of the students meet the friends in their leisure time. As for the actual condition of leisure activities, they enjoyed watching T.V and listening to the radio, reading and listening to music in weekdays, watching T.V and listening to the radio, reading and meeting friends in vacation, meeting friends, taking a rest and watching T.V, listening to the radio, in Sunday. The number of students demands their leisure activity fir traveling, mountain climbing and sports. In consideration of the strong influence of mass media such as television, eucational programs should be increased. 3. Conscience of the leisure activity. majority of the students feel the necessity of leisure activity because of their feeling -diversion and fatigue recovery. Their limitation of leisure activity is lack of time and money. So, in school and industries, the investment for leisure facilities should be increased, and the systemetic education for the information and methods of the leisure activity should be established.

복식 전자궁적출술후 절단부에 발생한 난관탈출증 1예

송은석,이해혁,김태희,김정식,남계현,이권해,고은석 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Prolapse of the fallopian tube into the vaginal vault after hysterectomy is a rare complication. Since most of cases may resolve before detection or remain undiagnosed, the exact incidence is still unknown. Though most common sign of tubal prolapse is tender friable tissue in vaginal cuff, with the simptoms of lower abdominal pain, dysparenunia, vaginal discharge, or postcoital spotting. The definitive diagnosis should be confirmed histologically Recently, we experienced a case of fallopian tube prolapse after abdominal hysterectomy in a 41-year-old woman and report with a brief review of the literature.

효율적인 군 전직지원체제 정립 방안

정철영,고재관,황원채,윤희철,박가열,김재호,이성식,김동승,표성일,이건남,양안나,최수정,김은석 한국직업능력개발원 2008 직업능력개발연구 Vol.11 No.1

이 연구의 목적은 제대군인에 대한 효율적인 전직지원을 위해서 현행 전직지원 프로세스에 대한 개선 안과 이에 따른 국방부, 국가보훈처 등 제대군인 전직지원관련 기관 간의 역할분담 및 연계방안에 대해서 제안하는 것이다. 연구는 크게 세 가지 과정을 거쳤다. 첫째, 국내 군 전직지원 실태를 분석하여 문제점과 시사점을 도출하였다. 둘째, 이러한 문제점과 시사점, 군 전직지원 선행연구를 종합하여 효율적인 군 전직지원 프로세스 안을 제시하였다. 셋째, 구축한 군 전직지원 프로세스 안에 따라 주요 군 전직지원 관련 기관인 국방부, 국가보훈처의 역할 분담 안을 제안하였다. This study aims to suggest an improvement plan for the support process of effective occupation change for discharged soldiers and then role assignments among related institutions for supporting discharged soldiers such as Ministry of Defense, Ministry of Patriots and Veterans Affairs, Ministry of Labor and the cooperation plan among the institutions. The study was made in three steps. First, after analyzing currents support facts and status for discharged soldiers, it induced its problems and implications. Second, integrating the findings of previous studies related to support plan on occupation changes for the discharged soldiers, Problems and implications mentioned above, it constructed effective occupation change process for discharged soldiers. Then, according to the established process, it suggested role assignments such as Ministry of Defense, Ministry of Patriots and Veterans Affairs, Ministry of Labor.