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RISS 인기검색어
- 검색키워드
- 저자 : Byung Suk Noh (검색결과 45 건)
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생체분해성 고분자를 이용한 사시수술용 제형개발 및 효용성에 대한 연구
민병무,김용백,김승영,김창식,박근성,길숙종,조항진,이성복,노승무,송규상,강대영,조준식,양준묵,정경수,최선웅,이진호,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1
A new device, muscle clamping system was developed to facilitate exact quatifying technique A strabismus surgery, and reduce the risk of complications. The device is composed of a lower fixing body with three jaws and an upper supporting body. They are used to clip an extraocular muscle and fix it to the sclera with a single bite. Superior rectus recession on 16 rabbit eyes were performed with this new device. Conjunctival injection, muscle adhesion strength, and light microscopic findings were examined at 1, 2, 4 and 8 weeks postoperatively. The Conjunctival injection were minimal, adhesion power ranged from 420 to 600 gram gravity, which is sufficient in withstand the normal pull of human extraocular muscle. In microscopic exam, some Inflammatory cells and fibrosis were found. The new device was technically easy, fast, and accurate, so it may be useful in stabismus surgery.
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생체분해성 망막압정을 이용한 망막고정에 대한 실험적 연구
김용백,민병무,김창식,박근성,김승영,길숙종,조항진,이성복,노승무,송규상,강대영,조준식,양준묵,정경수,최선웅,이진호,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1
Biodegradable retinal fixation devices obtain mechnical fixation of the retina with desirable chorioretinal scarring and with the potential for local, sustained release of antimetabolites and steroids to inhibit proliferative vitreoretinopathy. We manufactured a biodegradable retinal tack with barb that was designed in order to prevent intrusion from implantation of retinal tacks. This study was carried to evaluate the efficacy for retinal fixation and the capability for sustained release of drugs with a newly designed biodegradable retinal tack Biodegradable retinal tacks were made of polymers of glycolic acids and were designed with barbs in a shape to prevent the disinsertion. Biodegradale retinal tacks are divided into 3 parts, a conical portion that is inserted into the sclera, a cylinder portion that remains in the vitreous, and a neck portion between the pin and the cylinder. The tapered conical end was manufactured to allow easy insertion through the retina and choroid into the sclera. A cylinder portion was manufactured with a tapered angle that fixes firmly into the orifice of 19 gauge spinal needle. A neck portion, 0.4 mm in diameter, was designed to prevent disinsertion from following implantation of retinal tack. The applicator was a 19 gauge spinal needle and its orifice was prepared to 15°angle to accept the tapered cylinder portion of the retinal tack. The retinal tacks, secured in the needles, were passed through the formed vitreous and inserted into the retina, choroid, and sclera and were released by pushing the internal needle, usually within 2-3mm of the medullary ray of the posterior rabbit retina A retinal tack was placed in each of 8 pigmented rabbit eyes. Slit-lamp biomicroscopy, indirect ophthalmoscopy and fundus photography were performed periodically from 1 day to 8 weeks after surgery. Eight eyes were enucleated and studied by light microscopy at 8 weeks. Biomicroscopic evaluation of the animals revealed edemas adjacent to the retinal surfaces immediately after insertion of the biodegradable retinal tacks in all the animals. These edemas disappeared after 1 week. The first noticeable change in the size of retinal tacks was shown after 2weeks. The size of the retinal tacks gradually got smaller, decreasing to about one-half at 4 weeks and about one-third at 8 weeks. All retinal tacks remained in inserted places without any movement for an 8 week period. On light microscopy, epiretinal proliferations were seen to extend into the vitreous cavity. Cellular capsules that lined the inner aspect of the scleral defect caused by tack insertion were found. However the adjacent retina had a normal cytologic appearance and architecture in all specimens. We manufactured a biodegradable retinal tack that is designed to prevent intrusion from implantation of retinal tacks. All biodegradable retinal tacks reduce in size with time, but no retinal tacks extruded from the inserted place. The newly designed biodegradable retinal tack can be used for retinal fixation and may be used as a vehicle for the introduction of pharmacologic agents to prevent the cellular events that promote proliferative vitreoretinopathy.
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김창근,김강득,최시성,정선관,노병석,원종진 圓光大學校 醫科學硏究所 1994 圓光醫科學 Vol.10 No.1-2
In order to evaluate CT findings with time and to confirm the capsular structure correlating with its histopathologic findings, we experimentally induced ischemic necrosis of liver in 20 rabbits. Incision of the abdomen was performed under anesthesia. Ligation of hepatic artery, portal vein and hepatic duct of right inferior posterior lobe of the liver after injection of macroaggregated albumin into right inferior posterior portal vein in order to prevent from developing collateral circulation as possible. Precontrast and postcontrast enhanced CT images were obtained at 1. 2. 4 days and 1, 2. 4. 6 weeks after induction of ischemic necrosis. Necrotic area in the liver showed homogeneous low density compared to normal liver, and no contrast enhancement after contrast material administration, and marked volume loss with time. CT attenuation value of necrotic area at 1 day(36.7±6.4 M±SD, Hounsfield unit) approached to two third of that of normal liver(56.3±7.3) and showed no significant change until two weeks but increased significantly after four weeks. On contrast enhanced CT images, capsular structure was obsereved as a high density rim along the liver surface of the necortic area in 8 of 15 cases. From the first day on, homogenous ischemic or coagulation necrosis was observed but rarely findings of edema, hemorrhage and cystic change were observed on histopathologic specimen. In all of the histologic samples taken from 10 cases during th 2nd to 6th week, fibrous thickening with rich vascularity was observed along the surface of the necrotic area. In conclusion, ischemic necrosis of the liver showed homogeneous low density and no contrast enhancement. CT attenuation value of necrotic area increased significantly with time associated with markedly decrease in volume. Capsular structure attributed to the hypertrophy of the liver capsule and rich vascularity within it.
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노형진,김영백,박승원,황성남,최영덕,권정택,민병국,석종식 중앙대학교 의과대학 의과학연구소 2002 中央醫大誌 Vol.27 No.2
The aim of this study is to investigate the influence of various factors on the outcome of repeated lumbar spine surgery. Forty-three patients were enroled in this study. Mean follow-up duration was 39.5±2.2 months(range 7∼68months). Age,sex,smoking, symptom duration, symptom-free interval after operation,location of principal symptom, operative finding, existence of trauma after first operation, neuropsychiatric disorder and bone marrow density were the suspected prognostic factors of repeated lumbar spine surgery. Fisher's exact test were used for statistical evalution. 77% of the patients were satisfied with the result of reoperation. The number of operation, the existence of trauma after initial operation and location of principal symptom were the factors having significant influence on the result. Investigation of the repeated lumbar spine surgery cases with the knowledge of prognostic factors would be helpful for decision making in failed back surgery syndrome.
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Noh, Hyun Suk,Ingale, Santosh Laxman,Lee, Su Hyup,Kim, Kwang Hyun,Kwon, Ill Kyong,Kim, Young Hwa,Chae, Byung Jo Korean Society of Animal Sciences and Technology 2014 한국축산학회지 Vol.56 No.3
An experiment was conducted to investigate the effects of dietary supplementation with citrus pulp, fish by-product, and Bacillus subtilis fermentation biomass on the growth performance, apparent total tract digestibility (ATTD) of nutrients, and fecal microflora of weanling pigs. A total of 180 weaned piglets (Landrace ${\times}$ Yorkshire ${\times}$ Duroc) were randomly allotted to three treatments on the basis of body weight (BW). There were six replicate pens in each treatment with 10 piglets per pen. Dietary treatments were corn-soybean meal-based basal diet supplemented with 0 (control), 2.5, and 5.0% citrus pulp, fish by-product, and B. subtilis fermentation biomass. The isocaloric and isoproteineous experimental diets were fed in mash form in two phases (d 0 ~ 14, phase I and d 15 ~ 28, phase II). Dietary treatments had significant linear effects on gain to feed ratio (G:F) in all periods, whereas significant linear effects on ATTD of dry matter (DM), gross energy (GE), and ash were only observed in phase I. Piglets fed diet supplemented with 5.0% citrus pulp, fish by-product, and B. subtilis fermentation biomass showed greater (p < 0.05) G:F (phase I, phase II, and overall) as well as ATTD of DM, GE, and ash (phase I) than pigs fed control diet. Dietary treatments also had significant linear effects on total anaerobic bacteria populations by d 14 and 28. In addition, piglets fed diet supplemented with 5.0% citrus pulp, fish by-product and B. subtilis fermentation biomass showed greater (p < 0.05) fecal total anaerobic bacteria populations (d 14 and 28) than pigs fed control diet. Dietary treatments had no significant effects (linear or quadratic) on average daily gain (ADG), average dial feed intake (ADFI; phase I, phase II, and overall), or fecal populations of Bifidobacterium spp., Clostridium spp., and coliforms (d 14 and 28). These results indicate that dietary supplementation with 5.0% citrus pulp, fish by-product, and B. subtilis fermentation biomass has the potential to improve the feed efficiency, nutrient digestibility, and fecal microflora of weanling pigs.
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( Hyun Suk Noh ),( Santosh Laxman Ingale ),( Su Hyup Lee ),( Kwang Hyun Kim ),( Ill Kyong Kwon ),( Young Hwa Kim ),( Byung Jo Chae ) 한국동물자원과학회(구 한국축산학회) 2014 한국축산학회지 Vol.56 No.10
An experiment was conducted to investigate the effects of dietary supplementation with citrus pulp, fish by-product, and Bacillus subtilis fermentation biomass on the growth performance, apparent total tract digestibility (ATTD) of nutrients, and fecal microflora of weanling pigs. A total of 180 weaned piglets (Landrace × Yorkshire × Duroc) were randomly allotted to three treatments on the basis of body weight (BW). There were six replicate pens in each treatment with 10 piglets per pen. Dietary treatments were corn-soybean meal-based basal diet supplemented with 0 (control), 2.5, and 5.0% citrus pulp, fish by-product, and B. subtilis fermentation biomass. The isocaloric and isoproteineous experimental diets were fed in mash form in two phases (d 0 ~ 14, phase I and d 15 ~ 28, phase II). Dietary treatments had significant linear effects on gain to feed ratio (G:F) in all periods, whereas significant linear effects on ATTD of dry matter (DM), gross energy (GE), and ash were only observed in phase I. Piglets fed diet supplemented with 5.0% citrus pulp, fish by-product, and B. subtilis fermentation biomass showed greater (p < 0.05) G:F (phase I, phase II, and overall) as well as ATTD of DM, GE, and ash (phase I) than pigs fed control diet. Dietary treatments also had significant linear effects on total anaerobic bacteria populations by d 14 and 28. In addition, piglets fed diet supplemented with 5.0% citrus pulp, fish by-product and B. subtilis fermentation biomass showed greater (p < 0.05) fecal total anaerobic bacteria populations (d 14 and 28) than pigs fed control diet. Dietary treatments had no significant effects (linear or quadratic) on average daily gain (ADG), average dial feed intake (ADFI; phase I, phase II, and overall), or fecal populations ofBifidobacterium spp., Clostridium spp., and coliforms (d 14 and 28). These results indicate that dietary supplementation with 5.0% citrus pulp, fish by-product, and B. subtilis fermentation biomass has the potential to improve the feed efficiency, nutrient digestibility, and fecal microflora of weanling pigs.
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노석구 ( Suk Goo Noh ),여상인 ( Sang Ihn Yeo ),장병기 ( Byung Ghi Jang ),임채성 ( Chae Seong Lim ),송민영 ( Min Young Song ) 한국초등과학교육학회 2002 초등과학교육 Vol.21 No.2
The purpose of this research is to direct the 7th national primary science curriculum to be performed properly. The research is based on the questionnaire to investigate the primary teachers` appreciation of the curriculum. The questions are about the general aspect of the 7th curriculum and special treatises on science curriculum. Questionnaires were distributed to 1000 teachers, and 822 teachers answered them. According to the survey results the teachers` thoughts were as following: First, there must be enough time to develop a new curriculum. It is not desirable to change the old curriculum totally. There should be some continuity between the old and the new curriculum. Second, teachers appreciated that the learning resources and supplements were helpful, and interested students. Teachers thought that IT equipment at class or school was not enough. Third, according to them the hierarchical structure of science curriculum was appropriate, but the contents need to be improved. Fourth, most teachers restructured the 7th science curriculum to adapt it to the class and school. They cooperated with one another in teaching science, and applied diverse teaching-learning methods according to the curricular contents and the grade levels. Teachers tried to evaluate all aspects of the students with various methods, but they felt it was hard. They were ont active in developing evaluation tools as a team, and in objectifying the information about students. Fifth, teachers felt it was hard to implement the science curriculum according to different levels of the students. Based on the survey of teachers` thoughts, the following can be suggested for successful implementation and reorientation of the curriculum. First, teachers need learning opportunities to appreciate and adapt the 7th curriculum creatively. Second, they need guidances in implementing the different levels of the curriculum, and the information about the appropriate resources for it. Third, we need to control the relative difficulty of the curricular contents, and reduce the hours and quantity of the study. Fourth, we need to improve the school equipment and facilities. Networking and cooperation among education-related institutions are essential for better education. Fifth, it is desirable to develop concrete and diverse learning models.
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현병근(Byung-Keun Hyun),손연규(Yeon-Kyu Sonn),박찬원(Chan-Won Park),송관철(Kwan-Cheol Song),전현정(Hyen-Chung Chun),홍석영(Suk-Young Hong),문용희(Yong-Hee Moon),노대철(Dae-Cheol Noh),정소영(So-Young Jung) 한국토양비료학회 2012 한국토양비료학회지 Vol.45 No.4
최근 농경지의 급격한 감소와 더불어 도시화, 경지정리, 도로공사 및 혁신도시 건설 등으로 토지이용의 변화가 심하게 발생되고 있다. 특히, 토지이용 변화심화지역인 경기도 고양시, 충청남도 천안시, 강원도 원주시를 대상으로 토지이용변화실태, 토양특성변화양상, 토양도수정내용 및 기업도시 등으로 편입되는 지역의 토양환경분석을 하였다. 이에 대한 결과를 요약하면 다음과 같다. 1. 우리나라의 경지면적 (2011년)은 2009년대비 17.3 ha가 감소되었다. 논의 경우 24.2 ha가 감소되었으나, 밭의 경우에는 7.0 ha가 증가하였다. 2. 논의 면적 감소사유로는 논밭전환 (20.7 ha) > 공공시설 (3.2) ≥ 건물건축 (3.2) > 유휴지 (1.3) > 기타 (0.9)순이며, 밭 면적의 증가원인은 논밭전환 (20.7 ha) > 개간 (4.5) > 복구 (0.3) 순이었다. 논밭전환의 이유는 논 농사에서 농가소득이 높은 밭작물 내지 시설작물로 전환하는 것으로 생각된다. 3. 토지이용변화가 심한 해당시군의 농경지감소 (논, 밭, 과수)는 밭토양조사 (1995∼1999)당시와 비교 (2011년)할 때 고양시는 1,466 ha, 천안시 9,708, 원주시 6,980 ha가 감소되었으며, 1999년 대비 45%∼25%의 농경지가 급격히 감소되었다. 4. 환경부 토지이용피복도의 통계자료 활용성을 검토하기 위해 농식품부 통계자료와 비교시 지목별로 큰 차이가 있었다. 따라서, 추후 면밀한 검토를 통하여 활용 방안을 마련해야 할 것이다. 5. 원주시의 토양정보 변경내용을 보면 곡간지의 일부 논토양이 밭 또는 과수원으로 토지이용이 변경되었으며, 배수등급의 경우 도로건설 등으로 인해 저습화되는 등 해당 토양의 일부 특성정보가 변경되었다. 특히, 논토양의 경우 시설재배지, 밭, 과수원, 휴경, 성토화 등으로 토지이용의 변화가 심하였다. 6. 원주시 혁신도시에 편입되는 논토양은 급지가 떨어지는 3∼4급지가 대부분으로 3급지 70.8%, 4급지 29.2%이었다. 밭토양 역시 4급지가 88.7%인 토양으로 우량 급지가 혁신도시 건설에 속하지는 않았다. 앞으로 우량농경지보전을 위해 제도적 장치의 마련이 필요하다고 생각한다. Recently, agricultural lands decrease sharply, which was caused by urbanization, land consolidation, road construction, and innovation city construction, etc. In particular, Goyang, Chenan and Wonju city were had severe land use change. Therefore, we analyzed changes of land use, soil properties, and soil information in order to provide the basic soil information and soil management practice in these cities. The results are summarized as follows. The area of crop cultivated land in Korea (2011) was reduced to 17.3ha compared to ones from the previous year (2009). The paddy field decreased by 24.2 ha but, upland field increased by 7.0 ha. The reasons for the reduction of the paddy field were converting paddy field to upland (20.7 ha) > public facilities (3.2) ≥ building (3.2) > idle land (1.3) > and others (0.9). Other reasons for reduction in the upland field were switching upland to paddy field, (20.7 ha)>land developed (4.5) > and restoration (0.3) respectively. The main reason of converting paddy field to upland was changing from rice to more profitable upland or greenhouse crops. The cropland area (paddy fields, upland, orchard) of Goyang, Cheonan, and Wonju city were reduced to 1,466 ha, 9,708 ha and 6,980 ha respectively. The ratio of cropland area in each city was reduced by 45~25% dramatically compared to upland soil survey project in Korea (1995∼1999). These data were compared with MiFAFF statistics data to use for land use cover map of Ministry of environment. But they were differences significantly. Therefore, intensive investigation should be advised throughout the utilization plan. The paddy fields located in small valley in Wonju city were changed into upland or orchard. The drainage classes of soil have been deteriorated because the flows of water were intercepted by road construction and other disturbance to water flows. In particular, paddy fields have been changed to not only upland, orchard, greenhouse cultivation but also to fallow and soil dressing on paddy in Wonju city. The soil suitability classes of paddy field in Wonju innovation city were the 3rd grade for 70.8% of the area and the 4th grade for 29.2%. The soil suitability classes of upland was the 4th grade for 88.7% of the area. Fortunately, good soil suitability classes were not belong to innovation city in Wonju. So, the good farm land should be conserved and revise the related law.
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