환기정도에 따른 수술실용 신발 종류가 수술실 오염에 미치는 영향 : How to Choose Suitable Shoes?

남경동,정혜선,박영신,원진희,주미자,성화신,이지혜,이병희,조경숙,배재춘 한국의료QA학회 2000 한국의료질향상학회지 Vol.7 No.1

Background : Various types of protective footwear have been used to minimize bacterial contamination in operating rooms. In recent years, debate has arisen concerning the need for use of such protective footwear. This study was designed to provide useful data about choosing shoes most suitable for the surgical environment. Methods : Between November, 1999 and January, 2000, we performed this experimental study by comparing effect of three types of shoes (i.e., disposable shoescover, operating room-restricted shoes, and ordinary shoes) on bacterial contamination of operating rooms equipped with two different ventilation systems (i.e., high air-change, low air-change) respectively. Data were collected during two-hour sham operations in which subjects and their activities were strictly standardized. Bacterial flora were sampled from the study area floor and air colony-counts were measured. Results : In experiments involving high air-change ventilation system, there was a significant difference of floor contamination between three types of shoes, but no difference of air contamination. Under low air-change system, there was a significant difference of both floor and air contamination between three types of shoes. Conclusion : The results show that protective footwear would be unnecessary in the operating room with high air-change ventilation system, but it is important to choose suitable shoes carefully under low air-change system. Therefore, the use of outdoor shoes can be considered under high air-change system, but it would seem sensible to apply their first use in less bloody operations at the day surgery center or out-patient department to prevent transfer of body fluid into the outside environment.

체성분이 폐경 전후 여성의 골밀도에 미치는 여향

배성욱,남철현,신두만,차경미,서인선 慶山大學校 保健福祉硏究所 2002 保健福祉硏究 Vol.7 No.-

Objectives : To evaluate the degree of bone mineral density and prevalence rate of osteoporosis according to age and to search the preventive strategy for osteoporosis, the factors that affect on bone density were studied in Physical Characteristics of pre- and postmenopausal women in korea. Methods : The subjects were 961 premenopausal and 1,167 postmenopausal women who have examined in health promotion center of Yeungnam University Hospital in Daegu city from January, 1999 to January, 2001. The test for bone mineral density, biochemical factors, and body composition were done. Results : 1) The prevalence rates of reduced bone mineral density and osteoporosis in premenopausal women were 23.8% and 1.6%, respectively. However, these values were increased to 46.1% and 28.1% in postmenopausal women. 2) The body weight and height were important predictive factors for bone mineral density. The effects of age, body weight, and height on bone mineral density were 39%. The body weight was correlated statistically significantly with bone mineral density in pre- and postmenopausal women. The higher body mass index (BMI), the greater value of bone mineral density was revealed in pre- and postmenopausal women. 3) The correlation between body composition adjusted for body weight and bone mineral density revealed similar pattern between pre- and postmenopausal women. The height, lean body mass, muscle mass, mineral content, and mineral fraction were positively correlated with bone mineral density, however, body fat mass, percent body fat, waist/hip ratio, and BMI were correlated negatively with bone mineral density. 4) There was no direct correlation between cardiovascular risk factor and bone mineral density in this study, however, further study is needed because cardiovascular disease and osteoporosis have common risk factor and the prevention of osteoporosis can help to prevent cardiovascular disease. 5) In multiple regression analysis among bone mineral density as a dependent variable and independent variables (age, body weight, height, Ca/creatinine ratio, and alkaline phosphatase (ALP)), ALP revealed statistically significant inverse correlation with bone mineral density. Conclusions : These results suggested that to prevent osteoporosis, the systemized program including physical condition for promoting anti-osteoporotic factor have to be developed and apply from the thirties whom have maximal bone mineral density.

음양곽과 함초의 간독성에 대한 연관성

하배진,남천석,박은경,강금석 신라대학교 자연과학연구소 2006 自然科學論文集 Vol.15 No.-

In the present study the hepatoprotective and antioxidative effects of Epimedium koreanum (EK) and Salicornia herbacea (SH) were investigated against carbon tetrachloride (CCl_(4))-induced liver damage in rats. EK and SH (100 mg/kg) were administered into rats intraperitoneally (i.p) for 2 weeks. After CCl_(4) a dose of 3.3ml/kg was administered to induce hepatotoxicity. This antioxidative effects of EK and SH on CCl_(4) -treated rats were measured through the activity of Aspartate aminotransferase (AST), Alanine aminotransferase (ALT) in serum and Superoxide dismutase (SOD), Catalase (CAT) in liver tissue. EK or SH-administered and CCl_(4) -treated (ECT or SCT) groups showed inhibitory effects in AST and ALT activities compared to CCl_(4) -treated control (CTC) group. SOD and CAT in ECT and SCT groups were increased compared to those of CTC group.

중년후기 여성의 폐경관리와 삶의 질에 영향을 미치는 요인 분석

차경미,남철현,배성욱,서인선,김기열 慶山大學校 保健福祉硏究所 2002 保健福祉硏究 Vol.7 No.-

This study was conducted to identify influencing factors to management of menopause and quality of life and also to develope the developing education program of HRT(hormone replacement therapy) for healthy aging women. The hypothetical model explaining health promoting behavior and quality of life was constructed on the basis of Pender's health promotion model, Nho's quality of life model. The empirical data for testing the hypothetical model consisted of 356 late-middle aged(45~64) women who visited from 5th september to 20th september, 1999, in Pohang city. The reliabilities of instruments were adequate(Cronbach's alpha=0.7941, -0.9098). SPSS PC+ program were utilized for descriptive statistics and covariance structure analysis. The summary of research results was as follows: 1) The influential factors to management of menopause showed: The directed factors were the influences of family(β=.29), economical status(β=-.12), experienced symptoms of menopause(β=.24), multidimensional health locus of control(β=.15), subjective health status of compared with to another person(β=-.18). The indirected factors were the influences of family(β=.04), age(β=.05), experience of HRT's information(β=.02), belonging to occupation(β=-.03), stop of menstruation(β=-.02). 2) The influential factors to quality of life showed: The directed factors were the influences of family(β=.39), self efficiency(β=.15), subjective health status(β=-.31). The indirected factors were the influences of family(β=.37), age(β=-.97), belonging to occupation(β=.01), educational status(β=.21), a monthly income(β=.26). In conclusion, the purpose for "Healthy aging" in late-middle aged women is increasing of the quality of life after menopause. All the health providers have to efforts and harder study for developing health maintenances and health aging in late-middle aged women. Consequently, we need many kinds of public health education programs. And farther more, the developing HRT's educational program is very important in late middle-aged women's healthy aging.

고장으로 인한 대구경 계량기의 불감률

박남식,배정용,황경석,김학용,최철식 대한상하수도학회 2003 상하수도학회지 Vol.17 No.2

Leaks and meter under registrations are suspected as primary components of unaccounted-for water in Korea. Roughly, one third of the unaccounted-for water is believed to be due to meter under registration. However, no justification has been given to prove the statistics. In this study the rate of meter under registration due to failures of large-diameter meters is investigated. Replacement records of over 2600 consumer sites are analyzed. The minimum, the maximum and the probabilistic distribution of meter under registration rate are computed.

靑色 사파이어의 熱處理와 分光學的 特性

나경주,김원사,김문영,배인국,장영남 충남대학교 기초과학연구소 1994 연구논문집 Vol.14 No.-

For the blue sapphires from Santung, China, the color change before and after has been investigated by UV-Visible spectrophotometry method. The blue sapphires from Shantung show four groups of absorption bands: the bands A (374, 386 and 450 ㎚) being attributed to single Fe^3+ ion, the band B (560, 579 and 704 ㎚) to Fe^2+/Ti^4+ pairs, the band C (∼800 ㎚) to Fe^2+/Fe^3+ pairs, and the D (528 ㎚) to Ti^3+ dd transitions. From those UV-VIS characteristics the origin of blue color of the sapphires is confirmed to be attributed by the factors such as Fe^2+/Fe^3+ and Ti^3+/Ti^4+. The absorption spectra of natural blue sapphires before and after heat treatment show distintive features, comparing with those of sapphires from other localities: the bands of 689 ㎚ and of Cr^3+ are not recorded on the spectra of sapphires from Shantung. The band (492 ㎚), which resulted from Ti^3+, is not shown and the intensity of the band 528 ㎚ decreases after the heat treatment. Decoloration of ink-blue sapphires are found to be successful by heat treatment with the control of annealing and atmosphere. During the diffusion process the excess components of impurities contained originally in the host crystal were expelled to the surface of crystals, enhancing the transparency of the crystals noticeably.

익수환아의 예후에 영향을 미치는 인자에 관한 연구

김용배,정대봉,조수형,조남수,박영봉,박상기,김춘호,양은석,문경래 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.3

Drowning is the second most common cause of accidental death of children in Korea. But the study of near-drowning is very rare in Korea. The purpose of our study is to determine the factors that may influence survival on the basis of submersion time, consciousness state upon admission to hospital, the kinds of water, laboratory findings and neurological outcomes. The survey was performed by a retrospective cohort study on 28 near-drowning victims of less than 15 years of age who were admitted to the emergency room in the Chosun University Hospital between May 1988 & May 1997. The results were as follows :1)Sex distribution was 22 males and 6 females. 2) Submersion time was <5 minutes in 9 cases, 5-9 minutes in 6 cases, 10-14 minutes in 5cases, 15-19 minutes in 3 cases, ≥20 minutes in 5cases. 3) Comatose patients upon arrival were 6/7 cases in the death group(86%) and 2/21 cases in the improved group(10%). They had unfavorable outcomes(P<0.05). 4) The first PH value was mean 7.02±0.12 in the death group and mean 7.31±0.13 in the improved group. There was a statistically significant difference between the death and the improved group(P<0.05) 5) The patients who gad increased blood glucose concentration were all 7 cases in the death group and 12/22 cases in the improved group(54%). The mean blood glucose concentration was mean 424.7235.6㎎/㎗ in the death group and mean 140.182.7㎎/㎗ in the improved group. There was a statistically significant difference between the death and the improved group(P<0.05). 6) The patients who had pulmonary edema upon arrival were all 7 cases in the death group and 1/21 cases in the improved group(46%). They had unfavorable outcomes(P<0.05). 7) The patients who had been submerged more than 15 minutes were all 7 cases in the death group and 6/21 cases in the improved group(5%). They had unfavorable outcomes(P<0.05). We conclude that pediatric victims of near-drowning can be assigned to high or low likelihoods of unfavorable our outcomes with the use of five variables ; comatose mentation upon arrival decreased initial blood pH, increased initial blood glucose concentration, pulmonary edema, and maximum submersion time estimated longer than fiften minutes. This prediction rule may be useful if it can be validated in another cohort.

소각재 용융슬래그를 이용한 제올라이트 Na-A의 합성

장영남,채수천,배인국,류경원 한국광물학회 2005 광물과 암석 (J.Miner.Soc.Korea) Vol.18 No.1

소각재 용융슬래그를 출발물질로 하여 알카리 조건하에서 활성화시킴으로써 Na-A형 제올라이트를 합성하였다. 합성실험은 스텐레스 철재로 제작된 반응용기를 사용하였다. 출발물질은 슬래그 외에 수정인공합성 공장에서 배출되는 '규산질 수용액'과 NaA1O₂수용액을 사용하였는데, 전자의 화학조성은 SiO₂5.7 wt% Na₂O 3.2 wt%이고, 후자는 몰비가 Na₂O/A1₂O₃= 1.2와 H₂O/Na₂O=9의 조건으로 알루미늄 드로스와 NaOH 수용액을 반응시켜 제조하였다. 위에서 언급된 슬래그, '규산질 수용액' 그리고 NaAlO₂ 수용액을 혼합시킨 혼성물을 약 80℃에서 7~8시간 반응시키면 Na-A형 제올라이트가 단일상으로 합성되었다. 출발물질의 이상적인 혼합비율은 Na₂O : Al₂O₃: SiO₂의 물비가 1.3~l.4 : 0.8~0.9 : 2이었으며 반응용액과 슬래그의 비율은 1 : 7~10 (g/㏄)이었다. 합성된 제올라이트의 형태는 균일한 입방형이었으며 입도는 약 1 ㎛이었다. 한편, Ca^(²+)이온에 대한 이온교환 용량(CEC)은 180~210 meq/100 g이었으므로 통용되는 세제용 제올라이트와 비교하면 약 80% 수준이었으므로 폐수처리나 오염된 중금속처리와 같은 환경처리용으로 사용될 수 있을 것이다. Na-A zeolite were synthesized from melting slag of the incinerated ash by the alkaline activation processes. The experiments were performed in stainless steel vessels, with continuous stirring during the reaction periods. The silica-rich solution, a starting material, which was the waste of crystal growth factory, contains 5.7 wt% SiO₂ and 3.2 wt% Na₂O And NaAlO₂was made by the reaction of aluminium dross and NaOH solution and its molar ratios were Na₂O/ Al₂O₃ = 1.2 and H₂O/Na₂O=9. During the residence time of 7~ 8 h at 80℃, the mixing of the silica-rich solution, NaAlO₂and melting slag yields the production of homogeneous Na-A zeolite. The optimal reactant composition in molar ratio of Na_₂O : Al₂O₃: SiO₂was 1.3~l.4 : 0.8~0.9 : 2 and mixing ratio of solution and slag was 1/7~10 (g/㏄). Synthesized Na-A zeolite has cubic form uniformly and its size ranges about 1㎛. Ca^(²+) ion exchange capacity of the Na-A was about 180~210 meq/100 g, corresponding approximately 80% to the commercial detergent builder.

논의과정 활용 수업이 초등학생의 학습 동기와 과학태도와 미치는 영향

이하룡,남경희,문성배,김용권,이석희 한국초등과학교육학회 2005 초등과학교육 Vol.24 No.2

The purpose of this study is to examine the effects of science instruction using argumentation, with Tolumin's structure of argument, on students' learning motivation and scientific attitude. In the instruction, well-structured problems selected to be argument, in which interactions among students are stressed. The subjects were classified into two groups: One group is composed of sixty-seven students (experimental group) who were participated in solving processes of the scientific argument tasks, and the other is composed of sixty-nine students (comparative group) who were participated in the traditional teaching method. The results of this study implied that experimental group has a positive effect on students' learning motivation and scientific attitude.

Efavirenz, indinavir, lopinavir, ritonavir의 LC-MS/MS를 이용한 동시 정량법

채정우,배경진,백인환,서정원,이병요,이은주,남진경,강원구,권광일 충남대학교 약학대학 의약품개발연구소 2009 藥學論文集 Vol.24 No.-

Efavirenz indinavir and kaleta (co-formulation of lopinavir and ritonavir) are important antiretroviral drugs which have been proved to be human immunodeficiency virus (HIV) protease inhibitors and reduced the morbidity and mortality associated with HIV-1 infection. A brief and fast high performance liquid chromatography coupled with electrospray mass spectrometry (LC-MS/MS, API 4000) method for the determination of 4 anti-retroviral agents (efavirenz, lopinavir, indinavir, ritonavir) in human plasma was developed and validated. A simple protein precipitation method was used on 100μl of human plasma. And internal standard solution (10 ng/ml methaqualone) 1ml and reconstitution solution (MeOH) 1ml were added. After vortexing for 30 s and centrifuging at 13,200rpm for 10min, 2μl of supernatant was injected into the column (XTerra MS C_(18) column, 2.1mm × 50mm 3.5㎛ particle size). The mobile phase consisted of MeOH and 0.1% formic acid in water (80:20 , v/v). The chromatogram was run for 1.5 min at a flow rate of 300μl/min. A triple quadrupole mass spectrometer was operated in a positive ion mode (lopinavir, indinavir, ritonavir) and negative mode (efavirenz), simultaneously and multiple reaction monitoring (MRM) was used for drug quantification. The precursor-to-product ion transitions of m/z 316→69 (efavirenz) and 629→447 (lopinavir) and 614→421 (indinavir) and 721→296 (ritonavir)were used to measure and quantify the analyte. The limit of quantitation (LOQ) was 50 ng/ml (efavirenz, indinavir, ritonavir) and 100 ng/ml (lopinavir). The weighted (l/y²) calibration curve was linear over human plasma range 50∼5000ng/ml (efavirenz), 100∼20000ng/ml (lopinavir), 50∼10000ng/ml (indinavir), 50∼2000ng/ml (ritonavir), correlation coefficient(r²) of 4 antiretroviral agents were higher than 0.998. Accuracies and intra-run precisions ranged within 86.60 and 113.29%, 1.06 and 11.16% for all 4 drugs analysed. This analytical method used to determine these drugs was fast and easy to perform, with minimal sample preparation, and without compromising precision and accuracy. The developed method was successful to determine antiretroviral agents in human plasma, and proved suitable for clinical pharmacokinetic study.