지면으로 만나는 성품강연 : 김기열의 성품경영학 직원들의 만족도가 기업성과를 결정한다

김기열 한국성품협회 2014 성품저널 Vol.4 No.-

Disease Prediction Using Ranks of Gene Expressions

김기열,기동혁,정현철,라선영 한국유전체학회 2008 Genomics & informatics Vol.6 No.3

A large number of studies have been performed to identify biomarkers that will allow efficient detection and determination of the precise status of a patient’s disease. The use of microarrays to assess biomarker status is expected to improve prediction accuracies, because a whole-genome approach is used. Despite their potential, however, patient samples can differ with respect to biomarker status when analyzed on different platforms, making it more difficult to make accurate predictions, because bias may exist between any two different experimental conditions. Because of this difficulty in experimental standardization of microarray data, it is currently difficult to utilize microarray-based gene sets in the clinic. To address this problem, we propose a method that predicts disease status using gene expression data that are transformed by their ranks, a concept that is easily applied to two datasets that are obtained using different experimental platforms. NCI and colon cancer datasets, which were assessed using both Affymetrix and cDNA microarray platforms, were used for method validation. Our results demonstrate that the proposed method is able to achieve good predictive performance for datasets that are obtained under different experimental conditions.

Nomogram for Predicting Survival for Oral Squamous Cell Carcinoma

김기열,ShengJin Li,차인호 한국유전체학회 2010 Genomics & informatics Vol.8 No.4

An accurate system for predicting the survival of patients with oral squamous cell carcinoma (OSCC) will be useful for selecting appropriate therapies. A nomogram for predicting survival was constructed from 96 patients with primary OSCC who underwent surgical resection between January 1994 and June 2003 at the Yonsei Dental Hospital in Seoul, Korea. We performed univariate and multivariate Cox regression to identify survival prognostic factors. For the early stage patients group, the nomogram was able to predict the 5 and 10 year survival from OSCC with a concordance index of 0.72. The total point assigned by the nomogram was a significant factor for predicting survival. This nomogram was able to accurately predict the survival after treatment of an individual patient with OSCC and may have practical utility for deciding adjuvant treatment.

우담(愚潭)과 다산(茶山)에 대한 일연구

김기열 동국사학회 1986 동국사학 Vol.19 No.-

유비쿼터스 게임시대를 대비하자

김기열,Kim, Gi-Yeol 한국데이터베이스진흥원 2006 디지털콘텐츠 Vol.7 No.-

Possibility of the Use of Public Microarray Database for Identifying Significant Genes Associated with Oral Squamous Cell Carcinoma

김기열,차인호 한국유전체학회 2012 Genomics & informatics Vol.10 No.1

There are lots of studies attempting to identify the expression changes in oral squamous cell carcinoma. Most studies include insufficient samples to apply statistical methods for detecting significant gene sets. This study combined two small microarray datasets from a public database and identified significant genes associated with the progress of oral squamous cell carcinoma. There were different expression scales between the two datasets, even though these datasets were generated under the same platforms - Affymetrix U133A gene chips. We discretized gene expressions of the two datasets by adjusting the differences between the datasets for detecting the more reliable information. From the combination of the two datasets, we detected 51 significant genes that were upregulated in oral squamous cell carcinoma. Most of them were published in previous studies as cancer-related genes. From these selected genes, significant genetic pathways associated with expression changes were identified. By combining several datasets from the public database, sufficient samples can be obtained for detecting reliable information. Most of the selected genes were known as cancer-related genes, including oral squamous cell carcinoma. Several unknown genes can be biologically evaluated in further studies.

공기분리를 위한 압력스윙 흡착공정의 성능평가

김기열,서성정,서성섭 한국공업화학회 2005 응용화학 Vol.9 No.1

This work presents an experimental study of a pressure swing adsorption (PSA) unit running a traditional four cycle and a cycle with pressure equalization step for oxygen separation from air using a molecular sieve 5A. The effects of pressurization step duration, adsorption step duration, and pressure equalization step duration on the product purity, recovery, and productivity were investigated. The optimum operating conditions were observed for given oxygen purity in the product. The experimental results can provide guidance for searching appropriate operating conditions to achieve desired product quality in PSA process.

건설 중장비에 적용 가능한 내마모 강판 ( Wear Resistant Steel Plate for Heavy Duty Vehicle )

김기열,이범주,조정환,류영석,이동욱 한국트라이볼로지학회 1998 한국트라이볼로지학회 학술대회 Vol.27 No.-

에니어그램에 따른 중학교 발명영재학생과 일반학생의 발명 자기효능감 비교

김기열 한국실과교육학회 2015 한국실과교육학회지 Vol.28 No.4

This study compares and analyzes the invention self-efficacy of invention gifted students and general students classified according to Enneagram, and the findings of this study can be used as basic data to define the inventive giftedness difference between invention gifted and general students, and to create educational environments and develop educational programs for invention gifted. This study reached the following conclusions. First, middle school invention gifted students were classified as type 4(artist) and general students were classified as type 6(loyalist), according to Enneagram personality types. Both invention gifted students and general students show a harmonious graph of average personality type scores, suggesting that they have no difficulty putting their desires into energy. Invention gifted students' wing tendency is well-developed in type 3, and they are conscious of their surroundings, and are strongly inclined to receive love and attention. General students' wing tendency is well-developed in type 7, and they are very curious, like diversity, are amply imaginative, and regard their pleasure as important. Second, the correlation between Enneagram personality types and the invention self-efficacy represents the correlation coefficients ±0.85 ~ less than ±0.96, this means a very high correlation. For invention gifted students, the correlation coefficient between Enneagram personality types and self confidence in invention is .908, self confidence in accomplishment .899, expectation for achievement .901 showing a very high correlation. For general students, the correlation coefficient between Enneagram personality types and self confidence in invention is .915, self confidence in accomplishment .918, expectation for achievement .923 showing a very high correlation. Third, there was a statistically significant difference in the t-test of invention gifted students and general students regarding thinking-center(head) and feeling-center(heart) according to Enneagram (p<.05). It was found that invention gifted students, compared with general students, have a belief in inventive ability in thinking-center(head) and feeling-center(heart) rather than instinct-center(belly). In sub-areas, regardless of centers of energy self-confidence in invention and belief were higher with invention gifted students than with general students, making a significant difference (p<.05). Also, in terms of thinking-center(head), invention gifted students, compared with general students, more opt to analyze and think of inventive situations before putting their ideas to practice, thereby suggesting that there is a significant difference in their understanding and inventive thinking ability, belief in task performance ability. 이 연구는 에니어그램에 따른 발명영재학생과 일반학생의 발명 자기효능감에 대해 비교 분석하는데 있으며, 이러한 연구 결과는 발명영재와 일반학생과의 차별화된 발명영재성을 규명하고 발명영재를 위한 교육환경 조성 및 교육프로그램 개발하는데 기초자료로 활용할 수 있다. 이 연구를 통해 얻은 결론은 다음과 같다. 첫째, 중학교 발명영재 집단의 에니어그램 성격유형은 4유형(예술형)이고, 일반학생 집단은 6유형(충성형)이다. 발명영재와 일반학생 모두 성격유형 평균점수 그래프의 모양대가 원만하게 나타내어 자신의 욕구와 에너지를 발휘 하는 데는 어려움이 없는 원만함을 보이고 있는 것을 알 수 있다. 발명영재의 날개성향은 3유형이 발달하여 주위를 의식하면서 사랑, 관심을 받고 싶은 경향성이 많고 일반학생의 날개성향은 7유형이 발달하여 호기심이 많고 다양함을 좋아하며 상상력이 풍부하고 자신의 즐거움을 중요하게 여긴 경향성이 많다. 둘째, 전체 집단에 대한 에니어그램 성격유형과 발명 자기효능감 하위요인 간의 상관관계가 대부분 ±0.85 ~ ±0.96 미만의 상관계수를 나타내고 있으며, 매우 높은 상관관계를 나타낸다. 발명영재의 에니어그램 성격유형과 발명 자기자신감과의 상관계수 .908, 발명 수행자신감과의 상관계수 .899, 발명 성취기대감과의 상관계수 .901로 매우 높은 상관을 보였다. 일반학생의 에니어그램 성격유형과 발명 자기자신감과의 상관계수 .915, 발명 수행자신감과의 상관계수 .918, 발명 성취기대감과의 상관계수 .923으로 매우 높은 상관을 보였다. 셋째, 에니어그램에 따른 사고(머리) 중심, 감정(가슴) 중심에서 발명영재와 일반학생 간의 t-검정한 결과는 전체 평균에서 통계적으로 유의미한 차이가 있는 것으로 나타났다(p<.05). 발명영재와 일반학생을 비교하면 본능(장) 보다는 사고(머리), 감정(가슴) 중심에서 발명영재가 발명적 능력에 대한 신념을 갖고 있음을 알 수 있다. 하위 영역별로 살펴보면, 발명 자기자신감은 힘의 중심에 구분없이 발명영재가 일반학생 보다 신념이 더 높아 유의미한 차이가 있는 것으로 나타났음을 알 수 있다(p<.05). 또한 사고(머리)중심에서는 발명영재가 일반학생 보다 발명적 상황을 분석하고 생각한 후 실행하기 때문에 자신의 이해도 및 발명적 사고 능력, 과제수행능력에 대한 신념에서 유의미한 차이가 나타난 것으로 판단된다.

법률과 국가와 상담 ; 가정법과 상담

김기열 한국상담선교연구원 1996 상담과 선교 Vol.4 No.2

N/A N/A