외상후 스트레스장애 치료에 대한 중의학 임상연구 동향

최유진 ( Yu-jin Choi ),권찬영 ( Chan-young Kwon ),장재순 ( Jae-soon Jang ),정하영 ( Ha-young Jung ),김윤나 ( Yun-na Kim ),정선용 ( Sun-young Chung ) 대한한방신경정신과학회 2016 동의신경정신과학회지 Vol.27 No.3

Objectives: This study was performed to review the research trends in the treatment of posttraumatic stress disorder in traditional Chinese medicine. Methods: We searched articles in the China National Knowledge Infrastructure (CNKI) using keywords, “Posttraumatic stress disorder”, and “PTSD” in Traditional Chinese Medicine, Traditional Chinese Medicinal Herbs and Combination of Traditional Chinese Medicine and the Western Medicine field. We selected 16 studies after excluding non-clinical or unrelated studies. Results: Four pre-post comparison studies and 12 controlled clinical trials were performed in patients with PTSD in China. Herbal medicine, acupuncture, and moxibustion therapy were used for the treatment of PTSD. Most of the studies showed positive results, and they reported that the treatment groups had fewer side effects than the control group. However, the quality of these clinical studies was low. Conclusions: According to this study, TCM for PTSD would be an effective and safe intervention. Therefore, based on this study, more clinical

우황(牛黃).웅담(熊膽).사향(麝香) 약침을 이용한 Bell's palsy 환자의 이후통(耳後痛) 치험 6례

윤경진,최유진,여인호,김정현,이참결,노정두,이은용,Yun, Kyung-Jin,Choi, You-Jin,Yeo, In-Ho,Kim, Jung-Hyun,Lee, Cham-Kyul,Roh, Jeong-Du,Lee, Eun-Yong 척추신경추나의학회 2012 척추신경추나의학회지 Vol.7 No.2

Objectives : The aim of this study was to report Bell's palsy patients with postauricular pain treated by Calculus Bovis Fel Ursi Moschus(BUM) Pharmacopuncture. Methods : The 6 patients were treated by the Korean medica treatment including herbal medication, dry needle acupuncture and physical therapy. We performed BUM Pharmacopuncture in Yepung for the treatment of postauricular pain once or twice. We have evaluated the effect of BUM Pharmacopuncture by Visual Analog Scale(VAS). Results : After BUM Pharmacopuncture for the treatment of postauricular pain, VAS were decreased in all cases. Conclusions : It was suggested that BUM Pharmacopuncture might have effect on control of auricular pain in Bell's palsy. Further, systemic studies will be needed to evaluate obvious effect of BUM pharmacopuncture on postauricular pain of Bell's palsy.

청소년의 욕설사용에 대한 질적연구

손진희(Jin Hee Son),이영수(Young Soo Lee),최유진(Yun Jin Choi) 한국청소년문화연구소 2013 청소년 문화포럼 Vol.- No.33

This study is aimed at in-depth understanding of the youth cause the use of profanity. Routinely used profanity in adolescence adult for in-depth interviews were conducted. Navigate through the abusive use of these realities and the cause of the grounded theory method and analyzed inductively. Analysis, open coding and axial coding, selective coding, the core category of the categories were integrated. Paradigm centered study of the phenomenon, the analysis of the results of the abusive use of the process are derived. Youth culture environment and changes in relationships with peers and the older generations to share different cultures, distinctions were acting. This study, in the current situation, almost no studies about the profanity of the Youth Cultural Approach to the youth of the abusive use of a new approach to one culture may be shared implications are.

牛黃· 熊膽· 麝香 약침을 이용한 Bell’s palsy

윤경진(Yun Kyung-jin),최유진(Choi You-jin),여인호(Yeo In-ho),김정현(Kim Jung-hyun),이참결(Lee Cham-kyul),노정두(Roh Jeong-du),이은용(Lee Eun-yong) 척추신경추나의학회 2012 척추신경추나의학회지 Vol.7 No.2

Objectives : The aim of this study was to report Bell s palsy patients with postauricular pain treated by Calculus Bovis·Fel Ursi·Moschus(BUM) Pharmacopuncture. Methods : The 6 patients were treated by the Korean medica treatment including herbal medication, dry needle acupuncture and physical therapy. We performed BUM Pharmacopuncture in Yepung for the treatment of postauricular pain once or twice. We have evaluated the effect of BUM Pharmacopuncture by Visual Analog Scale(VAS). Results : After BUM Pharmacopuncture for the treatment of postauricular pain, VAS were decreased in all cases. Conclusions : It was suggested that BUM Pharmacopuncture might have effect on control of auricular pain in Bell s palsy.

갱년기 여성의 경항통에 대한 홍화 약침 치료의 임상적 고찰

박재연,윤경진,최유진,김민석,유성진,이참결,노정두,이은용,Park, Jae-Yeon,Yun, Kyung-Jin,Choi, You-Jin,Kim, Min-Seok,Yu, Sung-Jin,Lee, Cham-Kyul,Roh, Jeong-Du,Lee, Eun-Yong 대한약침학회 2011 Journal of pharmacopuncture Vol.14 No.4

Objectives: The purpose of this research was to examine the effect of Carthami-Flos Pharmacopuncture on posterior neck pain of menopausal women. Methods: We treated 20 female patients with neck pain patient(45-60 yr) into two groups and treated Group A with Carthami-Flos Pharmacopuncture and common acupuncture and Group B with common acupuncture. The efficacy of treatment was measured by VAS, NDI and MENQOL scores of before and after 30 days to start treatment. Results: Both group A and B represented effective improvement in VAS and NDI of neck pain and MENQOL scores. And group A was more effective than B group statistically. Conclusions: It was suggested that Carthami-Flos Pharmacopuncture treatment might have effect on posterior neck pain treatment of menopausal women.

중학생에서 사상성격검사(SPQ)의 생리심리적 타당화 연구

이수진,윤보미,최영준,최유진,윤여진,황보경,채한,Lee, Soo Jin,Yun, Bo Mi,Choi, Young Jun,Choi, Yu Jin,Yoon, Yeo Jin,Hwang, Bo Kyung,Chae, Han 사상체질의학회 2016 사상체질의학회지 Vol.28 No.3

Objectives The Sasang Personality Questionnaire (SPQ) measures the Yin-Yang temperament of Sasang typology with proven structural and clinical validity in adults, however it was not examined with teenagers. The purpose of this study was to validate the biopsychological structure of SPQ in middle school students.Methods 681 Korean high school students (356 boys and 325 girls) completed SPQ, Junior version of Temperament and Character Inventory (JTCI), and height and weight measures. The correlation between SPQ and JTCI subscales were examined, and the differences of SPQ and JTCI subscales, Body Mass Index (BMI) and Pondera Index (PI) among high (30%), middle (40%), and low (30%) SPQ total score groups were investigated with Analysis of Variance (ANOVA). The profile analysis was also performed to compare JTCI subscale profiles of three SPQ total score groups.Results The SPQ score was significantly (p<0.001) correlated positively with JTCI Novelty-Seeking and negatively with JTCI Harm-Avoidance. The JTCI Novelty-Seeking score of high SPQ group was significantly (p<0.001) higher than that of low SPQ group, and the JTCI Harm-Avoidance score of low SPQ group was significantly higher than that of high SPQ group. The JTCI subscale profiles for three SPQ groups were significantly different for boys and girls. Significant correlations or differences for the PI and BMI among SPQ groups were not found.Conclusions This study presented that the biopsychological structure of SPQ is robust as shown in adults. The SPQ would be a useful clinical measures of Sasang typology in pediatric patients.

성별영향분석평가제도의 실효성 제고와협력체계 활성화 방안(Ⅲ)

김경희(Kyung-Hee Kim),최유진(Yoo-Jin Choi),남궁윤영(Yun-Young Nam-Gung),임유미(Yu-Mi Im),장미현(Mi-Hyun Jang),강경민(Kyeong-Min Kang) 한국여성정책연구원(구 한국여성개발원) 2017 한국여성정책연구원 연구보고서 Vol.2017 No.-

In South Korea, the number of programmes which has undertaken Gender Impact Analysis and Assessment(GIAA) has been increasing and the areas in which GIAA has been implemented expanding, since GIAA was enacted in 2012. In the area of regional development, the outcome of policy improvement through GIAA has been particularly noticeable to the general population as well as women. This study is to identify what policy needs the general citizen have in the area of regional development with regard to gender issues, and to suggest the ways to enhance the cooperative system between policy actors of GIAA. As for the research methods, it includes the domestic and overseas literature analysis of GIAA about regional development, the content analysis of GIAA reports on regional development, interviews with experts and civil servants, and questionnaires of a thousand citizens. As a result of the questionnaire, policy needs for regional development have been identified as follows. Firstly, citizens expect to have economic activity infrastructure through city regeneration programmes and a better environment for crime prevention. Secondly, interests in safety are considerably high, and particularly, women are more sensitive to safety issues than men. Thirdly, as for the public facilities that citizens want to use, unless there are any problems, women have replied in following orders: culture(14.7%), life-long education(10.7%), and library(10.7%), whereas men library(13.6%), culture(13.0%), community health centre(10.1%). This suggests that it needs to improve facilities for better use. Lastly, more than half of respondents show their willingness to participate in the problem-solving activities concerning the use or safety of the public facilities: 51.4% and 70.7% respectively. This study has identified the methods to enhance the effectiveness of GIAA and regenerate the cooperative system as follows. Firstly, the Ministry of Land, Infrastructure and Transport needs to revise the legislations concerning regional development in a way to enhance gender equality and the committee of regional development needs to increase the rate of women in order to encourage women to take part in decision-making process. Secondly, it needs to find out gender issues in broader areas by undertaking specific GIAA in mid- and long-term regional development plans based on laws. To do so, gender experts must participate in this process to find out gender issues and reflect the findings for policy improvements into legislations, improvement of guidelines and gender budget reports. Thirdly, there needs to develop guidelines about GIAA for regional development. The checklist to be used to select programmes for GIAA should be made to notify whether programmes for regional development has items to improve gender equal use and arrangement of local spaces. Lastly, the Ministry of Gender Equality and Family needs to make a suggestion of the systemic operation of gender governance in the 2018 GIAA Guideline. Each public body needs to form GIAA Committee or Division Committee and include the support of monitoring and also the employment of gender officer in the Guideline. In order to do so, it needs to strengthen the regulation to support cooperation between private and public partnership, which is stipulated in the GIAA Act. Ⅰ. 서론 1. 연구의 배경 및 목적 우리나라가 성별영향분석평가를 본격적으로 시행한지 10년이 되었다. 성별영향분석평가는 성 주류화 정책을 위한 핵심 도구로 성인지 예산, 성인지 통계, 성인지 교육 등과 함께 공공정책의 성평등 실현을 목표로 운영되어 왔다. 그런데 이러한 성 주류화를 위한 관련 제도들이 긴밀하게 연계되어 운영되지 못했다는 비판이 제기되었고, 성평등을 위한 전략으로서의 성 주류화가 확산되기 위해서는 다양한 정책행위자들이 제도운영에 참여해야 한다는 의견이 제시되어 왔다. 성 주류화 제도화와 함께 ?성별영향분석평가법?이 제정된 2012년 이후에는 대상과제의 수가 양적으로 크게 확대되면서 다양한 정책분야에서 성별영향분석평가가 실행되었고 사회적 관심 또한 높아졌다. 특히 국민들의 생활에 직접적인 영향을 주는 지역개발분야의 경우 성별영향분석평가 결과에 기초한 정책개선의 성과가 국민들에게 미치는 영향이 크고, 정책개선으로 인한 만족도가 여성 뿐 아니라 남성을 포함한 가족 모두에게 영향을 줄 수 있다. 지역개발분야에서 수행된 성별영향분석평가를 연도별로 살펴보면, 대상사업의 수가 지속적으로 증가하고 있다. 그런데 기관유형별로 살펴보면, 중앙정부의 과제 수는 감소하고 있는 반면에 기초자치단체를 중심으로 지방정부의 과제 수는 증가하고 있다. 지방정부가 수행하는 사업 중에는 중앙정부가 지방자치단체에 위임한 사업이 대부분이어서 지방정부가 수행한 성별영향분석평가 결과에 기초해서 도출된 정책개선안이 정책 환류로 연결되기 위해서는 정부기관 간의 협력이 필요하다. 지방자치단체가 성별영향분석평가에 기초해서 제시한 정책개선안 중에는 소관법률이나 시행령, 규정, 지침 등을 개정해야 하는 경우가 있으며 이것은 중앙정부가 수행해야 할 역할이 될 것이다. 또한 정책개선안 중에서 여성의 참여를 높이기 위해서는 새로운 사업을 발굴하여 제시한 경우라면 별도의 예산편성이 필요하고 성인지 예산에 반영하기 위해 예산부서의 협조가 필요하다. 뿐만 아니라 사업수행방식을 개선해야 한다면 어떠한 방향으로 개선하는 것이 지역 주민들에게 유익할 것인지 등에 관해 시민사회와 협력해서 개선안을 마련하고 그 결과를 모니터링하는 활동이 수반되어야 한다. 더 나아가 지역개발 분야에서 수행된 성별영향분석평가 정책개선 사례를 살펴보면, 정부는 법률과 시행령, 지침 등에 정책개선안을 반영하여 성별영향분석평가제도의 실효성을 높이고자 하는 노력을 하고 있다. 그런데 지방정부의 경우 성별영향분석평가 대상사업 중 국토교통부 등의 중앙정부가 소관하는 법률에 근거해서 수행하는 국고 보조사업이 대부분이어서 성별영향분석평가 결과 제시된 정책개선안을 환류로 연결시키기 어려운 상황이다. 일부 지역에서는 시민단체가 중심이 되고 지역주민들이 참여하도록 해서 모니터링단을 구성한 다음, 성별영향분석평가 보고서를 모니터링하거나 도시재생사업 등의 지역개발분야 정부사업에 대한 성별영향분석평가 모니터링을 통해 정책개선안을 제시하는 사례가 발견되고 있다. 따라서 본 연구에서는 지역개발분야 성별영향분석평가서에서 제시된 성별 요구 등에 대한 내용분석을 토대로 젠더이슈를 파악하는 한편, 일반인들이 지역개발분야에서 어떠한 정책적 요구를 갖고 있는지 파악함으로써 성별영향분석평가제도의 실효성을 제고시킬 수 있는 방안을 모색하고자 한다. 또한 일부 지방정부를 중심으로 지역개발분야에서의 모니터링 활동이 활발해지고 있는 상황변화에 주목하고 사례분석을 통해서 지역개발분야에서의 성별영향분석평가 정책행위 주체들 간의 협력체계 활성화 방안을 제시하고자 한다. 2. 연구내용 본 연구에서는 첫째, 2015년에 작성된 성별영향분석평가 보고서에 대한 내용분석을 통해서 지역개발분야의 다양한 정부사업에 대한 성별영향분석평가 결과 제시된 성별 요구와 정책개선안을 파악하고자 하였다. 둘째, 성별영향분석평가제도를 운영하면서 민관협력의 거버넌스 체계의 구축 활동이 활발한 지역 및 정책행위자들 중 여성의원의 참여가 활발한 지역인 두 지역에 대해서 젠더 거버넌스의 특성을 파악하고자 사례분석을 실시하였다. 셋째, 지역에 거주하는 여성과 남성이 지역사회 생활 여건에 대해 어떠한 의견을 갖고 있으며, 공공시설 이용 시 어떠한 요구를 갖고 있는지 등을 파악하기 위해 일반인 1,000명을 대상으로 설문조사를 실시하였다. 마지막으로 민관협력에 기초한 성별영향분석평가 모니터링 활동이 활발했던 전라남도 사례분석을 위해서 전남 여성플라자와 공동연구를 수행하였다.

네트워크를 활용한 바이모달트램용 차량운영컴퓨터

이강원(Lee Kang Won),윤희택(Yun Hee Taek),최유진(Choi Yu Jin),황의경(Hwang Eui Kyung) 한국철도학회 2009 한국철도학회 학술발표대회논문집 Vol.2009 No.11월

The networking VOC(vehicle operation computer) developed for bimodal tram is accomplishing the variable functions such as broadcasting, wireless communication, display and information service. VOC is connected with the UOC(unified operation center) in the ground through wireless communication. VOC can send data like vehicle status or camera images to UOC and can receive the variable information like whether, real time news or useful data from the UOC. This paper has introduced VOC and its functions which was already installed on the developed bimodal tram and now is giving a test in the test track.

보문 : 밀리타리스 동충하초 열수추출물의 멜라닌 분비 억제능 효과

남병혁 ( Byung Hyouk Nam ),조월순 ( Wool Soon Jo ),최유진 ( Yoo Jin Choi ),이재윤 ( Jae Yun Lee ),강은영 ( Eun Young Kang ),정민호 ( Min Ho Jeong ),이재동 ( Jae Dong Lee ) 한국균학회 2010 韓國菌學會誌 Vol.38 No.2

The present study aims to evaluate Cordyceps militaris water extract (CMWE) with a view to develop melanogenesis inhibitors. Inhibitory activities of CMWE against tyrosinase, L-DOPA(L-3,4-dihydroxyphenylalanine) oxidation, and melanin biosynthesis in B16 mouse melanoma cells were investigated. CMWE, at 5000 μg/ml, inhibited tyrosinase activity of 71% and DOPA oxidation of 40% as reacting with L-DOPA. Furthermore, B16 mouse melanoma cell survived over 50% from low to high dose on MTT assay, and CMWE markedly inhibited (>50%) melanin synthesis at 5000 μg/ml. The inhibitory effect of CMWE on melanogenesis was attributed to enhancement of tyrosinase degradation. Key enzyme of melanin biosynthesis is tyrosinase which catalyses a beginning step from tyrosine to DOPA quinine and melanin formation step, respectively. These results indicated that CMWE may be a potential source of novel whitening agents for cosmetic or therapeutic application.

더덕, 도라지 표고균사발효물의 유용성분 및 생리활성

고영우,윤경원,김경제,진성우,임승빈,하늘이,정희경,김승주,김복선,최유진,송다혜,서경순,Koh, Young-Woo,Yun, Kyeong-Won,Kim, Kyung-Je,Jin, Seong-Woo,Im, Seung-Bin,Ha, Neul-I,Jeong, Hee-Gyeong,Kim, Seung-Ju,Kim, Bok-Seon,Choi, Yu-Jin,Song, Da 한국버섯학회 2021 한국버섯학회지 Vol.19 No.4

한약재로 사용되는 더덕과 도라지에 표고의 유용성분을 함유한 소재를 개발하고자 더덕표고균사발효물(FCLM)과 더덕도라지균사발효물(FPLM)을 제조하였다. 두 가지 발효물의 일반성분, 유리당, 유기산, 𝛽-glucan, ergothioneine, ergosterol, vitamin D₂ 함량 및 3T3-L1 지방전구세포의 분화에 미치는 영향을 연구하였다. 일반성분 분석결과, FCLM에서 조섬유와 조지방함량이 FPLM에 비하여 높게 나타났으며, FPLM은 조단백질과 가용성무질소물의 함량이 FCLM에 비하여 높게 나타났다. 유리당은 FCLM과 FPLM 모두 arabinose, glucose, sucrose 3종이 검출되었으며, 총 유리당 함량은 FPLM에서 높게 나타났다. 유기산 함량은 발효 전 더덕과 도라지에 비하여 발효 후 FCLM과 FPLM에서 낮게 나타났다. 𝛽-Glucan 함량은 FCLM과 FPLM 두 발효물에서 대조구로 사용한 표고보다 높은 함량을 보였다. 항산화 물질로 알려진 ergothioneine의 함량은 FCLM이 FPLM보다 높게 나타났다. Ergosterol 함량은 대조구로 사용한 표고에서 가장 높게 나타났으며, 발효물들은 비슷한 함량을 나타내었다. Vitamin D₂는 발효물들에서만 검출되었으며, FPLM (0.58±0.01 mg%)가 FCLM (0.47±0.01 mg%)보다 높은 함량을 보였다. 더덕과 도라지 표고균사발효물인 FCLM과 FPLM는 3T3-L1 지방전구세포에 대하여 발효 전 더덕과 도라지에 비하여 높은 수준의 세포 생존율을 나타내었다. 또한 FCLM과 FPLM은 3T3-L1 지방전구세포 분화를 발효 전 더덕과 도라지에 비하여 높은 수준으로 억제하여, 비만 억제 효과가 있는 것으로 기대된다. This study was conducted to develop food and medicinal products containing useful components of Lentinula edodes in Codonopsis lanceolata and Platycodon grandiflorus for use as herbal medicine. We manufactured C. lanceolata (FCLM) and P. grandiflorus (FPLM) extract fermented with L. edodes mycelium. The effect of the two fermented products on proximate composition, free sugar, organic acid, 𝛽-glucan, ergothioneine, ergosterol, and vitamin D₂ levels, and 3T3-L1 preadipocyte cell growth were studied. The proximate composition analysis results showed that the crude fiber and crude fat content in FCLM was higher than that in FPLM, and the crude protein and soluble nitrogen content in FPLM was higher than that in FCLM. Free sugar analysis detected arabinose, glucose, and sucrose in both FCLM and FPLM, and the total free sugar content was high in FPLM. The organic acid content was lower in FCLM and FPLM compared to C. lanceolata and P. grandiflorus before fermentation. The 𝛽-glucan content was higher than that of L. edodes used as a control in both fermented products, FCLM and FPLM. The content of ergothioneine, an antioxidant, was higher in FCLM than in FPLM. Ergosterol content was highest in L. edodes which was used as a control, and the two fermented products showed similar content. Vitamin D₂ was detected only in FCLM and FPLM, and FPLM (0.58±0.01 mg%) showed a higher vitamin D₂ content than FCLM (0.47±0.01). FCLM and FPLM showed a higher level of cell viability for 3T3-L1 pre-adipocytes compared to non-fermented C. lanceolata and P. grandiflorus. In addition, FCLM and FPLM inhibited 3T3-L1 preadipocyte differentiation more than C. lanceolata and P. grandiflorus before fermentation, which may exert an anti-obesity effect.