肩臂痛의 鍼治療에 있어서 順經取穴과 接經取穴의 比較 硏究

이참결,장소영,김현중,김동조,김기태,유희정,위종성,이은용 대한침구의학회 2005 대한침구의학회지 Vol.22 No.6

Objectives : The purpose of this report is to examine the effect of Jiejing-Quxue in the Shoulder pain patient. Methods : Clinical studies were done 40 patients who were treated with shoulder pain to Dept. of Acupuncture & Moxibusition, of Oriental Medicine Se-Myung University from August 1, 2005 to October 28, 2005. Subjects were divided into two groups Shunjing-Quxue needling group(Group A) and Jiejing-Quxue needling group(Group B). In Shunjing-Quxue needling group, we treated patients with one acupunture point on one meridian pathway. In Jiejing-Quxue needling group, we treated patients with two each acupunture points on two each meridian pathways. For evaluating satisfaction of patients, we use the method for Martin. A.N. to present. For evaluating change of pain, Visual Analog Scale(VAS) was examined after each treatment. Results : In satisfaction of patients, the patients of Group B were more satisfied than them of Group A. The VAS score of Group B were decreased significantly compared to that of Group A.(p<0.05) Conclusion : The Jiejing-Quxue acupunture treatment may be good effects on the Soulder pain. So we suggest the possibility to use this treatment for Shoulder pain.

Clinical Efficacy and Safety of Gyebutang Granules Combined with Acupuncture for the Treatment of Knee Osteoarthritis: Protocol for a Multicenter, Randomized, Assessor-blinded, 2-armed Parallel, Controlled Trial

이참결,강하라,이연선,성원석,임지연,Jung Chan-yung,김은정,서병관,백용현,김경호,이은용 대한침구의학회 2020 대한침구의학회지 Vol.37 No.2

Background: Due to the aging population in Korea, knee osteoarthritis (KOA) has become an increasingly common condition. Many patients with KOA prefer analgesics, herbal medicines, acupuncture, or exercise, rather than arthroscopic surgery or a knee replacement. Gyebutang (GB) granules are a herbal extract widely used to treat KOA in traditional Korean medicine, but there is insufficient evidence of its efficacy and safety.Methods: A multicenter, randomized, assessor-blinded, 2-armed parallel, controlled clinical trial has been designed to investigate the efficacy and safety of GB combined with acupuncture for the treatment of KOA. There will be 100 patients with KOA enrolled in the study from 3 traditional Korean medicine hospitals. The participants will be randomly allocated to an experimental group (GB and acupuncture) or a control group (celecoxib and acupuncture) in a 1:1 ratio. Both groups will receive acupuncture treatment once a week for 6 weeks; one group will receive GB and the other will receive celecoxib for the same duration.Results: The primary outcome will be the change of knee osteoarthritic pain, based on scores on a 100 mm visual analog scale. The secondary outcomes will be scores on a numeric rating scale, the Western Ontario and McMaster Universities osteoarthritis index, patient global assessment, European quality of life 5-dimension 5-level scale, and adverse events.<br>Conclusion: The results of this study will provide evidence of efficacy and safety of GB as a treatment for patients with KOA.

대금음자 약침이 알코올 독성 흰쥐의 해마에서 c-Fos 발현에 미치는 영향

이참결,이은용 대한침구의학회 2006 대한침구의학회지 Vol.23 No.3

Objectives : The study was conducted to investigate the effect of Deakumeumja herb-acupuncture on c-Fos expression in each area of the hippocampus of Alcohol intoxicated rats. Methods : Experimental groups were divided into five groups ; normal group, the alcohol-treated (control) group, the alcohol- 1 ㎎/㎏ Daekumeumja treated (sample A) group, the alcohol- 5 ㎎/㎏ Daekumeumja treated (sample B) group, the alcohol- 10 ㎎/㎏ Daekumeumja treated (sample C) group (n = 6 for each group). Rats of normal group were injected intraperitoneally with saline once a day for 5 consecutive days, while animals of the alcohol-treated (control) group were injected once a day with 2 g/kg of alcohol for the same duration of time. Animals of the alcohol and Daekumeumja-treated (sample A, B, C) groups were acupunctured at Chung-wan(CV12) with 2 g/kg of alcohol and the appropriate amount of Daekumeumja extract once a day for 5 days. Each groups was evaluated by the changes of c-fos-positive neurons in each area of the hippocampus by using an image analyzer and microscope. Results : 1. In the CA1 region of the hippocampus, the number of Fos-positive cells in the sample B, C groups were significantly increased compared with the control group. 2. In the CA2-3 regions of the hippocampus, the number of Fos-positive cells of the sample B, C groups were significantly increased compared with the control group. 3. In the Dentate gyrus region of the hippocampus, the number of Fos-positive cells of the sample C group was significantly increased compared with the control group. Conclusion : c-fos expression in each area of the hippocampus was reduced in alcohol-intoxicated groups. Treatment of Daekumeumja increased this reduction. In conclusion, it can be suggested that Daekumeumja possesses protective effects of the amnesia and learning disability in alcoholism.

국내 말초성 안면마비의 침 임상시험에 대한 체계적 고찰

이참결 대한침구의학회 2013 대한침구의학회지 Vol.30 No.3

Objectives : This study was designed to evaluate clinical evidence of acupuncture treatment for peripheral facial palsy in South Korea. Methods : All process was independently proceeded by two investigators. Literature search was performed in 9 databases from their inception to February 2013. Searched reports was twice excluded for title, abstract and body. And then, data extract and analysis was done before assessing risk of bias by Cochrane Handbook. Results : 10 randomized controlled trials(RCT) were finally included. 4 RCT handled postauricular pain with facial palsy. All articles at least used in combination with two treatments. Interventions like pharmacopuncture, electroacupuncture, scalp acupuncture etcetera were conducted as treatment to evaluate efficacy, and some study reported advantageous effects of treatment group compared to baseline or control group. Adverse events didn’t referd to in any studies. In assessing risk of bias, indefinite and uncertain information made all included trials to have a high risk of bias. Conclusions : Because of methodological deficit, there is no sufficient evidence to allow any conclusion about the efficacy of acupuncture for peripheral facial palsy. Therefore, well designed trials with high quality is needed from now on.

동결견 환자에 대한 한방보건 프로그램의 효과

이참결 대한침구의학회 2011 대한침구의학회지 Vol.28 No.6

Objectives : The purpose of this research was to investigate the effect of oriental medicine public-health program on frozen shoulder patients. Methods : Oriental medicine public-health program was done to 50 frozen shoulder patients who visited Eumseong-gun public health center. Oriental medicine treatment(twice a week for 12 weeks) and prevention-educaiton program was included in public-health program. The schedule was proceeded from 16th March 2010 to 3rd June 2010. The efficacy of program was measured by visual analog scale (VAS), ROM(range of motion), Apley scratch test and Life function score, sleep quality score of their first and last visit. Then we analyzed the improvement in the same group. Results : 1. In VAS change, program showed statistically significant improvement. 2. In ROM(flexion, extension, abduction, adduction) and apley scratch test, program showed statistically significant improvement. 3. In Life function score, program showed statistically significant improvement. 4. In sleep quality score, program also showed improvement, but didn’t do statistical significans. Conclusions : The above results suggest that oriental medicine public-health program can be used as effective method for frozen shoulder's treatment and care.

A Case Study of 20 Patients with Lateral Epicondylitis of the Elbow by Using Hwachim (Burning Acupuncture Therapy) and Sweet Bee Venom Pharmacopuncture

정세호,이참결,여인호,성희진,노정두,조나영,이은용 대한약침학회 2014 Journal of pharmacopuncture Vol.17 No.4

Objectives: This study was performed to estimate the effectiveness of burning acupuncture therapy (Hwachim) and sweet bee venom pharmacopuncture (S-BV pharmacopuncture) in treating lateral epicondylitis of elbow. Methods: We selected 33 patients at first, but 13 patients were excluded due to unclear medical records. Finally, a total of 20 patients who had received treatment from January 2012 to December 2013 were included in this study; all 20 patients had undergone Hwachim for the treatment of lateral epicondylitis of elbow, and 19 of the 20 had been treated with S-BV pharmacopuncture (Korea Pharmacopuncture Institute, KPI) and transcutaneous electrical nerve stimulation (TENS) as an ancillary treatment method. The degrees of pain of the 20 patients were evaluated by using the visual analogue scale (VAS) score at their first and final visits. The Wilcoxon signed rank test and the Kruskal-Wallis test were used to compare the VAS scores statistically. Results: The VAS score had decreased significantly from 10.00 ± 0.00 to 4.00 ± 2.47 (P = 0.000) by the end of the treatment. No significant changes were observed based on the number of treatments (P = 0.246), the age of the patients (P = 0.810), the duration of the illness (P = 0.705), and the location of the lesion (P = 0.076). Conclusion: This study suggests Hwachim and S-BV pharmacopuncture are very effective for treating lateral epicondylitis of the elbow.

A Systematic Review and Meta-Analysis of Moxibustion for Knee Osteoarthritis

박장미,이참결,김경호,김은정,정찬영,서병관,구본혁,백용현,이은용 대한침구의학회 2020 대한침구의학회지 Vol.37 No.3

The purpose of this study was to evaluate the evidence supporting the effectiveness of moxibustion treatment for osteoarthritis. There were 9 databases used to retrieve randomized controlled trials (RCTs) that used moxibustion as treatment for osteoarthritis. The quality of methodology for the RCTs was assessed using the Cochrane Risk of Bias tool [Review Manager (RevMan) Version 5.3 Windows, The Nordic Cochrane Centre, Copenhagen, Denmark]. The inclusion criteria for this review was met by 27 RCTs. All studies were conducted in China. A 4-week moxibustion treatment period was the most common. EX-LE4 and SP10 and GB34 acupoints were most frequently selected in the treatment of osteoarthritis. The most commonly used evaluation index was the visual analog scale (VAS). All studies, including a meta-analysis showed that moxibustion treatments were statistically significantly effective at treating knee osteoarthritis. However, welldesigned randomized RCTs without a high risk of bias should be designed in the future.

Effects of Salviae Miltiorrhizae Radix Hot Aqueous Extract on Nitric Oxide and Prostaglandin E2 Production and on 1,1-diphenyl-2-picryl hydrazyl Radical Scavenging in Macrophages

여인호,이참결,이은영 대한약침학회 2014 Journal of pharmacopuncture Vol.17 No.1

Objectives: The objective of this study is to investigate the effects of Salviae Miltiorrhizae Radix hot aqueous extract on nitric oxide (NO) and prostaglandin E2 (PGE2) production and on 1,1-diphenyl-2-picryl hydrazyl (DPPH) free-radical scavenging in macrophages. Methods: Salviae Miltiorrhizae Radix (300 g) was heated at 100℃ with distilled water (2 L) for 4 hours. The extract was filtered and concentrated to 100 mL by using a rotary evaporator, was frozen at -80℃, and was then freeze-dried by using a freezing-drying system. The RAW 264.7 macrophage was subcultured by using 10-㎍/mL lipopolysaccharide (LPS). In order to evaluate cytotoxicity, we performed (3-(4,5-dimrthylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) (MTT) assays and measured the cell viability. The NO production was measured by using Griess assays, and the PGE2 production was measured by using enzyme immunoassays. The antioxidant activity, the 1,1-diphenyl-2-picryl hydrazyl (DPPH) free-radical scavenging capability, was measured by using the DPPH method. Results: Cell viability with the 1-, 5-, 25-, 125- and 625-㎍/mL Salviae Miltiorrhizae Radix hot aqueous extract was not significantly decreased compared to the cell viability without the extract. When 125 and 625 ㎍/mL of Salviae Miltiorrhizae Radix hot aqueous extract were used, nitric oxide (NO) production in LPS-stimulated RAW 264.7 macrophages was significantly inhibited compared to that in the control group. When 25, 125, and 625 ㎍/mL of Salviae Miltiorrhizae Radix hot aqueous extract were used, PGE2 production in LPS-stimulated RAW 264.7 macrophages was significantly inhibited compared to that in the control group. The 125- and 625-㎍/mL Salviae Miltiorrhizae Radix hot aqueous extracts had high DPPH free-radical scavenging capabilities in RAW 264.7 macrophages. Conclusion: This study indicates that Salviae Miltiorrhizae Radix hot aqueous extract suppresses NO and PGE2 production and improves DPPH free-radical scavenging capability. Thus, it seems that Salviae Miltiorrhizae Radix hot aqueous extract may have an anti-inflammation effect and antioxidant activity.

經筋刺法을 이용한 上肢部 신경포착증후군에 대한 임상적 고찰

윤경진,최유진,이참결,이은용,노정두 대한침구의학회 2012 대한침구의학회지 Vol.29 No.1

Objectives : To broaden understanding about meridian tendino-musculature acupuncture on nerve compression syndrome of upper limbs and to evaluate the effect of meridian tendino-musculature acupuncture on nerve compression syndrome of upper limbs. Methods and Results : From June 1st to Oct. 31th, the patients were outpatients for treatment of nerve compression syndrome of upper limbs in department of acupuncture and moxibustion, traditional Korean medical hospital, Semyung University and treated with meridian tendino-musculature acupuncture. To evaluate the effect of meridian tendino-musculature acupuncture, thickness of muscle by medical skinfold caliper, coding result(arbitary values used to evaluate results) and VAS(Chief complain) were used. As a result, muscle atropy and symptoms are improved remarkably. Conslusions: Meridian tendino-musculature acupuncture was found to be helpful to patients who wish to recover from their muscle atropy and symptoms of upper limbs. In order to make this meridian tendino-musculature acupuncture more available, we should pay more attention to improving treatment appliance and acupuncture technique.

기능성 소화불량증에 대한 저빈도, 고빈도 전침의 효능 비교 연구: 무작위배정, 이중맹검(피험자, 평가자), 평행군 설계

여인호,이은용,이참결 대한침구의학회 2014 대한침구의학회지 Vol.31 No.3

Objectives : The purpose of this study is to investigate the efficacy of the electroacupuncture with different frequency on functional dyspepsia. Methods : We observed 30 functional dyspepsia patients from May, 2013 to June, 2014. This study was randomized and double blinded. The patients were divided into two groups. One group(group A) was treated with 3 ㎐ electroacupuncture and the other group(group B) was treated with 300 ㎐ electroacupuncture. We evaluated the treatment effect of each group by using visual analogue scale(VAS) and pressure algometer. Results :1. Functional dyspepsia was significantly improved in group treated with 3 ㎐ electroacupuncture. 2. Functional dyspepsia was significantly improved in group treated with 300 ㎐ electroacupuncture. 3. As a result of evaluation there were no statistical significance between two groups. Conclusion : Both 3 ㎐ and 300 ㎐ electroacupuncture has significant effect on functional dyspepsia. But there is no significant difference between 3 ㎐ and 300 ㎐ electroacupuncture.