종오리에서 Riemerella anatipestifer 감염증례

백수연,서혜숙,강민,송희종,장형관 한국가금학회 2013 한국가금학회 정기총회 및 학술발표회 Vol.2013 No.11

Prediction of Late Breast Cancer-Specific Mortality in Recurrence-Free Breast Cancer Survivors Treated for Five Years with Tamoxifen

백수연,권지영,이영주,곽성찬,이새별,김지선,정일용,고범석,김희정,김성배,안승도,공경업,손병호,안세현,이종원 한국유방암학회 2019 Journal of breast cancer Vol.22 No.3

Purpose: The extension of endocrine therapy beyond 5 years for recurrence-free survivors of breast cancer improves survival; however, the issue on how to clinically identify appropriate candidates remains controversial. This study aimed to identify prognostic factors for breast-cancer-specific mortality in patients who have had 5 years of tamoxifen treatment and categorize subgroups based on the risk of death using combinations of these prognostic factors to assist in the clinical decision to perform further endocrine therapy. Methods: In total, 3,158 patients with breast cancer were enrolled. Breast cancer-specific survival rates after 5 years of tamoxifen treatment were calculated, and associated prognostic factors were analyzed using a Cox proportional-hazards model. Results: An age extreme at diagnosis (i.e., < 40 or ≥ 60 years), tumor size > 2 cm, and positive lymphovascular invasion were robust independent prognostic factors for late breast cancer-specific death in tamoxifen-treated patients (hazard ratio [HR] = 2.162, 1.739, and 1.993; p = 0.001, 0.047, and 0.011, respectively). Lymph node metastasis and progesterone receptor negativity had borderline significance in this regard (HR = 1.741 and 1.638, p = 0.099 and 0.061). The study patients were classified into four groups according to the number of prognostic indicators, i.e., low, intermediate, high, and extremely high risk. The additional 5- and 10-year cumulative risks of breast cancer-specific death were 0.8% and 1.5% in the low-risk group, 0.9% and 3.9% in the intermediate-risk group, 1.3% and 7.3% in the high-risk group, and 4.8% and 13.8% in the extremely high-risk group, respectively. Conclusion: This new risk stratification system for late mortality in breast cancer can be used to identify the right candidates for extended endocrine therapy after 5 years of tamoxifen treatment.

Recurrent Pericardial Effusion with Feline Infectious Peritonitis in a Cat

백수연,조재금,송근호,서경원 한국임상수의학회 2017 한국임상수의학회지 Vol.34 No.6

A five-month-old, male Domestic Korean shorthair was referred to our hospital with a history of lethargy, anorexia, and globoid cardiac silhouette on thoracic radiography. Physical examination showed dehydration and anemia was revealed on blood analysis. On thoracic radiography and echocardiography, the patient showed pericardial effusion and ultrasound-guided pericardiocentesis was performed. A Rivalta test of the pericardial effusion showed a positive result. As the patient had recurrent pericardial effusion, pericardiectomy was performed. He was tentatively diagnosed with wet form feline infectious peritonitis (FIP) and treated with Polyprenyl immunostimulant (PI). Neurological signs were eventually seen and he was euthanized. Histopathologic changes with markedly expanded neutrophils, lymphocytes, plasma cells, and macrophages with fibrous connective tissue and collagenous fibers were detected. Immunohistochemistry for FIP antigen was performed and results showed FIPV-positive multifocal aggregates of cells. Pericardial effusion is an atypical condition in cats with FIP, but can be presented. This case report describes FIP with pericardial effusion in a cat, in which definitive diagnosis of FIP was done using biopsy via pericardiectomy.

Effects of Mobile Healthcare Applications on the Lifestyle of Patients With Breast Cancer: A Protocol for a Randomized Clinical Trial

백수연,이새별,이유라,정석훈,최창민,이휘정,조민우,윤성철,이종원 한국유방암학회 2022 Journal of breast cancer Vol.25 No.5

Purpose: Physical activity (PA) in patients with breast cancer is associated with improved quality of life (QoL); however, many breast cancer survivors do not meet the recommended PA level. This study aims to evaluate the effect of digital health interventions using mobile apps to promote PA and QoL in patients with postoperative breast cancer. This study will also identify effective digital intervention methods and perform an economic analysis. The main hypothesis is that the use of mobile healthcare apps will improve health-related quality of life (HRQOL), promote PA, and reduce healthcare costs. Methods: The Promotion of a better lifestyle (PA) with Precise and Practicable digital healthcare in postoperative CANCER patients through a Multi-Disciplinary Network (P4CancerMDnet) study is examined by a prospective 4-group randomized controlled trial with a concurrent cost–utility evaluation. Patients are randomly assigned to 3 different mobile app intervention groups or control groups in a 1:1:1:1 ratio. The intervention group is encouraged to use the assigned mobile app. The targeted outcomes are HRQOL, metabolic health markers, and quality-adjusted life-years. The outcomes will be measured at the 6- and 12-month follow-ups. Discussion: This study will contribute towards a better lifestyle and HRQOL through digital healthcare for postoperative breast cancer patients. These findings are expected to provide evidence of the effectiveness of mobile apps for breast cancer survivors. Trial Registration: Clinical Research Information Service Identifier: KCT0005447

NFT의 거래상 법적 논점에 관한 소고 - 소유권 이전, 권리소진, 추급권을 중심으로 -

백수연 서울대학교 기술과법센터 2022 Law & technology Vol.18 No.4

자유학기제 수업을 위한 학생 참여 중심의 수학 교수?학습 자료 개발 - 미래 사회 핵심역량의 증진을 중심으로

백수연,신인선 한국수학교육학회 2014 수학교육 학술지 Vol.2014 No.2

무엇을 위한 유아국악인가?

백수연 열린전북 2006 열린전북 Vol.2006 No.5

자유학기제 수업을 위한 학생 참여 중심의 교수,학습자료 개발 및 효과 연구 -미래사회 핵심역량의 변 화를 중심으로

백수연,신인선 한국수학교육학회 2014 뉴스레터 Vol.30 No.5

자유학기제는 학생들이 스스로 꿈과 끼를 찾고, 자신의 적성과 미래에 대해 탐색 ? 고민 설계하는 경험을 통해 지속적인 자기성찰 및 발전할 수 있는 기회를 제공하고, 지식과 경쟁 중심의 교육을 자기주도적인 창의학습 및 미래지향적 역량 함양이 가능한 교육으로 전환하여 공교육의 변화 및 신뢰회복을 통해 학생이 행복한 학교생활 을 제공하는데 그 목적이 있다 이에 본 연구는 자유학기제가 추구하는 목표와 기본방향에 부합하면서 실제 현장 에서 실천 가능한 학생 참여 중심의 교수학습 자료를 개발하여 적용하고자 한다 특히 이러한 학생 참여중심의 수업을 통해 학생들의 수학적 태도 및 미래사회에 펼요한 핵심역량 신장에 긍정적인 변화를 줄 수 있을 것인지 그 효과를 연구하는데 그 목적이 있다 이를 위해 자유학기제에 해당하는 중학교 1학년 2학기, 상반, 하반 한 학 급씩을 대상으로 통계 프로젝트 수업을 설계하여 적용해 본 후, 교사관찰일지와 모둠 포트폴리오, 수업을 촬영한 비디오 전사 자료 등을 다각적으로 분석할 것이다. 개발한 프로젝트 수업의 적용 결과로 학생들의 수학적 태도 뿐 아니라 기초학습능력, 정보처리능력, 문제해결능력, 의사소통능력, 그리고 인성과 유사한 대인관계능력과 같 은 핵심역량의 신장에 있어 긍정적인 변화가 있을 것으로 예상한다.

단지형 대학 기숙사의 거주환경요소가 기숙사생활 적응에 미치는 영향에 관한 연구

백수연,최재필 대한건축학회 2020 대한건축학회논문집 Vol.36 No.1

Dormitories of Korean university are planned to pursue qualitative growth after a period of quantitative growth in the 1970s. However, sincethe 1990s, the physical plan for qualitative growth has not changed significantly and the effects of these changes on dormitory residents hasnot been verified. The purpose of this study is to identify the environmental factors influencing dormitory life adaptation and to provide abasis for qualitative growth of university dormitories to help dormitory residents adapt to the environment. The research was conducted inthree stages. First, the elements of the residential environment of the dormitory complex, which is an independent variable, were derived. Thedormitory life adaptation scale was developed to measure the dependent variable. Secondly, a questionnaire survey was conducted to obtainthe environmental factors of current dormitory and previous residence and three elements of dormitory life adaptation; ‘acceptance of change’,‘familiarity’, and ‘anxiety’. Third, statistical analysis was conducted to determine whether each factor influenced dormitory life adaptation. 국내 대학 기숙사는 1970년대 양적 성장을 추구하던 시기를 지나 1990년대부터 질적 성장을 추구해왔다. 그러나 2000년대 이후 질적 성장을 위한 물리적 계획은 크게 달라지지 않았으며, 기존의 변화 역시 기숙사 거주자들에게 어떤 영향을 미치는지 검증된 바 없다. 따라서 질적 성장에 의한 기숙사환경 변화를 점검하고, 이를 바탕으로 새로운 질적 성장의 방향을 모색해야할 필요가 있다. 이에 본 연구는 ‘기숙사생활 적응’에 집중하여 이에 영향을 미치는 환경요소를 파악하고자 하였다. 또한 이를 분석하여 기숙사 거주자의 환경적응을 돕고 대학 기숙사의 질적 성장을 위한 바탕을 마련하고자 하였다. 연구는 세 단계에 걸쳐 진행되었다. 우선 독립변수인 단지형 대학 기숙사의 거주환경요소를 도출하고 이를 분석대상지인 서울대학교 관악학생생활관에 적용하였으며 종속변수를 측정하기 위한 기숙사생활 적응 척도를 개발하였다. 두 번째로는 설문조사를 실시하여 현재 거주중인 대학 기숙사의 거주환경요소와 이전 거주지의 거주환경요소, 기숙사생활 적응의 세 가지 요인점수를 확보하였다. 세 번째로는 통계적 분석을 통해 각 거주환경요소가 기숙사생활 적응에 영향을 미치는 요소인지 판별하였다.

Multidisciplinary Shared Decision Making for Fertility Preservation in Young Women With Breast Cancer

백수연,김홍규,박석호,유종한,이민혁,윤현조,김현아,한재홍,최정은,이정렬,이경훈,정석훈,채희동,김선옥,유소영,함상근,김희정 한국유방암학회 2023 Journal of breast cancer Vol.26 No.6

Purpose: Fertility preservation (FP) is an important issue for young survivors of breast cancer. Although international guidelines recommend pre-treatment fertility counseling for women with breast cancer, there is no standardized protocol or referral system for FP in South Korea. There are also barriers to discussing FP that make patient-centered decision making difficult. This study aimed to develop a shared decision making program for FP and compare the rates of FP procedures between the usual care and shared decision making groups. We hypothesized that multidisciplinary shared decision making for FP would increase the rate of FP procedures and patient satisfaction. Methods: The multidisciplinary shared decision making for FP in young women with breast cancer (MYBC) is a multicenter, clustered, stepped-wedge, randomized trial. A total of 1100 patients with breast cancer, aged 19–40 years, from nine hospitals in South Korea, will be enrolled. They will be randomized at the institutional level and assigned to usual care and shared decision making groups. Four institutions, each of which can recruit more than 200 patients, will each become a cluster, whereas five institutions, each of which can recruit more than 50 patients, will become one cluster, for a total of five clusters. The shared decision making groups will receive multidisciplinary programs for FP developed by the investigator. The primary outcome is the rate of FP procedures; secondary outcomes include fertility results, satisfaction, and quality of life. Outcomes will be measured at enrollment, treatment initiation, and the 1-, 3-, and 5-year follow-ups after starting breast cancer treatment. Discussion: A multidisciplinary shared decision making program for FP is expected to increase fertility rates and satisfaction among young patients with breast cancer. This study will provide the evidence to implement a multidisciplinary system for patients with breast cancer. Trial Registration: ClinicalTrials.gov Identifier: NCT05139641. Registered on December 1, 2021.