Die theoretische und programmatische Entwicklung der Sozialdemokratischen Partei Deutschlands(Resiimee)

Kim Sung Hi(金成熺) 한국정치학회 1967 한국정치학회보 Vol.2 No.-

비알코올성 지방간과 대사증후군 및 혈청 카로테노이드와의 관련성

박선균,이현정,이덕희,이성국,천병렬,김성애,이혜성,손효경,김성희,Park, Sun-Kyun,Lee, Hyun-Jung,Lee, Duk-Hee,Lee, Sung-Kook,Chun, Byung-Yeol,Kim, Sung-Ae,Lee, Hye-Sung,Son, Hyo-Kyung,Kim, Sung-Hi 대한예방의학회 2008 예방의학회지 Vol.41 No.1

Objectives : This study was conducted to investigate the associations of non alcoholic fatty liver with metabolic syndrome and the serum carotenoids. Methods : This study was conducted in a general hospital in South Korea from November, 2004 to August, 2005. The study subjects were 350 sampled persons who were aged from 40 years and older (males : 180, females : 170). They were grouped into the normal, mild and severe groups according to fat accumulation in their livers, as determined by ultrasonography. We analyzed the association between non alcoholic fatty liver and metabolic syndrome by multiple logistic regression analysis and we analyzed the association between non alcoholic fatty liver and the serum carotenoids by a general linear model(ANCOVA). Results : After adjustment for the effect of potential covariates, the prevalence of metabolic syndrome was associated with fat accumulation in the liver (p trend <0.001). If the odds ratio of normal group is 1.00, then that of the mild group is 2.80 (95% C.I=1.17-6.71) and that of the severe group is 7.29 (95% C.I=2.76-19.30). The prevalence of metabolic alterations fitting the criteria of metabolic syndrome, according to the class of fat accumulation in the liver, was significantly increased, except for criteria of high blood pressure, a large waist circumference and low HDL (high density lipoprotein) cholesterol level (p trend <0.001). The level of serum ${\beta}$-carotene was decreased according to the class of fat accumulation in the liver (p trend=0.036), but the levels of serum ${\alpha}$-carotene, lycopene, ${\beta}$-cryptoxanthin and lutein were not decreased. Conclusions : This study shows that non alcoholic fatty liver was associated with metabolic syndrome and with the serum ${\beta}$-carotene level.

배합사료 급여 횟수가 조피볼락의 성장, 사료효율 및 체성분에 미치는 영향

이상민(Sang-Min Lee),김성희(Seong-Hi Kim),전임기(Im-Gi Jeon),김선명(Sun-Myoung Kim),장영진(Young Jin Chang) 한국수산과학회 양식분과 1996 韓國養殖學會誌 Vol.9 No.4

한국 노인의 사회경제적 취약과 인지기능장애의 상관관계

박상균(Sang Kyun Park),황영시(Young Si Hwang),오병택(ByungTaek Oh),이준영(Jun Young Lee),홍승완(Seung Wan Hong),김성희(Sung Hi Kim),김대현(Dae Hyun Kim) 대한임상노인의학회 2017 대한임상노인의학회지 Vol.18 No.2

Background: The relationship between socioeconomic status and cognitive dysfunction is still unknown. The aim of this study is to determine the relationship between cognitive impairment and socioeconomic vulnerability on elderly people in Korea by Korean Longitudinal Study on Aging (KLoSA). Methods: Authors collected data from Korean Longitudinal Study on Aging (KLoSA). Cognitive function was assessed by the Korean version of the mini-mental state examination-Korea (MMSE-K). And, the authors created the socioeconomic vulnerability (SEV) score, consisted of 6 items. Those 6 items are education level, house income, social engagement score, self-related economic satisfaction percentage, private insurance and residence. Results: A total of 4,044 participants were included and 2,045 subjects were classified as cognitive impaired whose MMSE is lower than 23. SEV score was significantly different between normal and cognitive impairment group. Authors divided four SEV groups by SEV severity. Increased SEV score was significantly correlated with cognitive impairment group (Odds ratio SEV Q2: 2.84, Q3: 5.69 and Q4:10.67). In addition, diabetes mellitus (1.29, 1.06∼1.61), depression (1.23, 1.04∼1.46), function (ADL: 2.48, 1.61∼3.82, IADL: 1.95, 1.54∼2.47) also correlated with cognitive impairment. Conclusion: Socioeconomic vulnerability was strongly correlated with cognitive impairment. Depression, diabetes and independent functionality (ADL, IADL) were also significant correlated with cognitive impairment.

Fluoxetine 및 Sertraline으로 유도된 심한 세로토닌 증후군 1예

전진숙,이상신,김성희,조웅,Cheon, Jin-Sook,Lee, Sang-Shin,Kim, Sung-Hi,Cho, Woong 대한생물정신의학회 2001 생물정신의학 Vol.8 No.1

A 54-year old male patient who was suffering from bipolar I disorder for 19 years and was admitted to the National Bugok Mental Hospital due to a depressive episode, was referred to the Kosin University Gospel Hospital. On arrival at the emergency room, he had confused mentality with disorientation, memory impairment, hypomania, marked anxiety and hyperirritability. The change of neuromuscular activity such as ataxia, gait disturbance, tremor, shivering, myoclonus and epileptic seizures was also shown. In addition, the symptoms and signs of autonomic instability including diaphoresis, tachycardia, hypotension, fever and facial flushing were noticed. The above symptoms developed after the administration of sertraline successive to the discontinuation of fluoxetine without any washout period. The degree of severity seemed to be severe because he had epileptic seizures, fever and hypotension. He was recovered from the severe serotonin syndrome by the supportive symptomatic treatment with sodium valproate, clonazepam, lorazepam and cyproheptadine after cessation of the selective serotonin reuptake inhibitors during hospitalization. Therefore, this rare case of severe serotonin syndrome was reported and related literatures were also reviewed.

부재료의 첨가에 따른 절임배추의 숙성 중 Chlorophyll 및 그 유도체의 함량변화

김경업(Gyeong-Eup Kim),김성희(Sung-Hi Kim),정효숙(Hyo-Sook Cheong),이종호(Jong-Ho Lee) 한국식품영양과학회 2000 한국식품영양과학회지 Vol.29 No.4

각종 부재료를 각각으로 첨가한 절임배추를 제조하여 5℃와 15℃에서 13일간 저장하면서 pH, 산도 및 아스코르브산의 함량변화를 측정하고 chlorophyll분해 및 그 유도체의 생성과의 관계를 검토해 보았다. 발효 중의 pH저하와 산도의 증가는 온도가 높을수록 뚜렷하여 온도와의 관련성이 높은 것으로 나타났고, 첨가한 부재료의 영향을 보면 마늘, 고추가루 및 젓갈은 pH의 저하나 산도의 증가를 촉진하였고, 파와 생강은 큰 영향이 없었으며 겨자와 갓은 억제하는 효과가 있는 것으로 나타났다. 5℃ 및 15℃의 발효기간 중 아스코르브산의 잔존량은 대체적으로 갓을 첨가한 절임배추가 높았고, 멸치액젓을 첨가한 절임배추가 가장 낮게 나타났다. Chlorophyll의 분해는 발효기간 중 대체로 아스코르브산의 함량이 높았던 갓을 첨가한 절임배추에서 낮은 경향을 보였으나 발효기간중 아스코르브산의 잔존량이 전반적으로 높았던 마늘을 첨가한 절임배추에서 chlorophyll의 분해가 심하였고, pheophytin과 pheophorbide생성량이 크게 증가하는 것으로 나타났는데 이는 산도의 증가와 pH의 감소가 가장 크게 나타난 것과 일치되었다. 따라서 발효 중의 chlorophyll의 분해는 아스코르브산 함량변화와도 연관이 있을 뿐만 아니라 역시 산의 생성에 의한 pH의 감소와 관련성이 있었다. The brined Korean cabbage (BKC) with various ingredients was stored at 5℃ and 15℃ for 13 days to examine the changes in pH, total acidity, ascorbic acid, and chlorophylls. Decrease in pH and increase in total acidity in the BKC stored at 15℃ were greater than in the BKC stored at 5℃, indicating these changes are closely related to the storage temperature. The effect of ingredients was various: garlic, red pepper powder, and fermented anchovy juice accelerated the decrease in pH and increase in total acidity ; mustard powder and leaf mustard suppressed their changes and green onion and ginger had no effect. At both temperatures, ascorbic acid was remained at high level in the BKC with leaf mustard, but it was maintained at lowest level in the BKC with fermented anchovy juice. Degradation of chlorophylls was slow in the BKC with leaf mustard, which maintained the high level of ascorbic acid during storage. Meanwhile the degradation of chlorophylls was severely fast in the BKC with garlic, which maintained moderately high level of ascorbic acid, resulting in greatly increase in the production of pheophytin and pheophorbide. Degradation of chlorophylls or production of pheophytin and pheophorbide was consistent with the production of acid. These results suggest that degradation of chlorophylls in BKC was positively correlated with ascorbic acid content and the acid produced during storage.

혈청 Gamma-Glutamyltransferase에 따른 복부비만과 제2형 당뇨병간의 관련성: Korean Genome and Epidemiology Study

신지연,황준현,정진영,김성희,문재동,노상철,김영욱,김양호,임종한,주영수,홍영습,하은희,이용환,이덕희,김동현,Shin, Ji-Yeon,Hwang, Jun-Hyun,Jeong, Jin-Young,Kim, Sung-Hi,Moon, Jai-Dong,Roh, Sang-Chul,Kim, Young-Wook,Kim, Yang-Ho,Leem, Jong-Han,Ju, Yo 대한예방의학회 2009 예방의학회지 Vol.42 No.6

Objectives : This cross-sectional study was performed to examine if the serum gamma-glutamyltransferase (GGT) level that is within its normal range is associated with the risk of type 2 diabetes and if the association between the waist hip ratio (WHR) and type 2 diabetes is different depending on the serum GGT levels. Methods : The study subjects were 23,436 persons aged 40 years or older and who participated in regular health check-ups at 11 hospitals (males: 5,821, females: 17,615). The gender-specific quintiles of the serum GGT and WHR were used to examine the associations with type 2 diabetes. Results : The serum GGT levels within their normal range were positively associated with type 2 diabetes only in women. The adjusted odds ratios (ORs) were 1.0, 1.0, 1.4, 2.1, and 2.5 according to the quintiles of the serum GGT ($p_{trend}$<0.01). The WHR was more strongly associated with the prevalence of diabetes among the women with a high-normal serum GGT level as compared with those with a low-normal serum GGT level (p for interaction=0.02). For example, the adjusted ORs for women with a low normal serum GGT level were 1.0, 1.2, 1.5, 2.2, and 2.4 according to the quintiles of the WHR, while those figures were 1.0, 2.4, 3.6, 5.0, and 8.3 among the women with a high normal serum GGT level. However, in men, the serum GGT was very weakly associated with type 2 diabetes and the association between the WHR and type 2 diabetes was not different depending on the serum GGT level. Conclusions : Serum GGT within its normal range was positively associated with type 2 diabetes, and central obesity was more strongly associated with the prevalence of type 2 diabetes when the serum GGT level was highnormal. However, these associations were observed only in women, which is different from the previous findings. The stronger relation between central obesity and type 2 diabetes among women with a high-normal serum GGT level can be useful for selecting a group that is at high risk for type 2 diabetes irregardless of whatever the underlying mechanism is.

파, 부추 및 고들빼기김치 숙성 중의 Chlorophyll 및 그 유도체의 함량변화

김경업(Gyeong-Eup Kim),김성희(Sung-Hi Kim),정효숙(Hyo-Sook Cheong),유영법(Young-Bob Yu),이종호(Jong-Ho Lee) 한국식품영양과학회 1999 한국식품영양과학회지 Vol.27 No.6

한국의 전통발효식품인 파김치, 부추김치, 고들빼기김치를 제조하여 5℃와 20℃에서 13일간 저장하면서 염도, pH, 산도 및 ascorbic acid 함량의 변화를 측정하고 chlorophyll분해 및 그 유도체생성과의 상관관계를 검토하였다. 모든 시료 김치에서 발효기간 동안 염도는 온도와 상관없이 큰 변화를 나타내지 않았으나, pH는 발효가 진행됨에 따라 감소하였고 산도는 증가하였는데 특히 발효 3일째에 가장 현저하게 나타났다. Ascorbic acid의 함량은 발효온도와 상관없이 부추김치가 가장 높았고, 고들빼기김치에서 가장 낮게 나타났다. Chlorophyll함량은 온도에 관계없이 발효기간 동안 pheophytin과 pheophorbide로 분해되었으며 특히 pH의 감소 및 산도의 증가가 두드러졌던 발효 3일째에 현저하게 나타났다. Chlorophyll함량의 감소와 pheophytin, pheophorbide생성량의 증가는 발효 중 ascorbic acid의 함량이 높게 유지되었던 부추김치에서 가장 낮게 나타났고 초기부터 급격한 감소를 보였던 고들빼기김치에서 가장 높게 나타났다. 따라서 김치 중의 chlorophyll의 분해 및 pheophytin, pheophorbide의 생성은 김치에 함유된 ascorbic acid 함량과 정의 상관성이 있었다. Three types of Korean traditional kimchi were prepared using green onion, leek or godulbaegi as raw materials and stored at 5℃ and 20℃ for 13 days. Changes in salt and ascorbic acid contents, pH and total acidity as well as the relationship of the decomposition of chlorophylls and the production of their derivatives were investigated. For the all kimchi samples tested, salt content was not significantly changed during storage at both temperatures, whereas pH and total acidity were decreased and increased, respectively. Especially their remarkable changes were shown at the third day of storage. Ascorbic acid content was remained at high level in the leek kimchi for the experimental period at both storage temperatures, meanwhile godulbaegi kimchi retained the least amount of ascorbic acid. Chlorophylls were decomposed to pheophytin and pheophorbide during storage at both storage temperatures, and this phenomenon was apparent at the third day of storage. Reduction of chlorophylls and increasements of its decomposed products such as pheophytin and pheophorbide were the least in leek kimchi and the greatest in godulbaegi kimchi during storage at both temperatures. These results indicate that decomposition of chlorophylls in kimchi and increasements of pheophytin and pheophorbide were closely related to the ascorbic acid content in kimchi.

배추, 열무 및 갓김치 저장 중의 Chiorophyll 및 그 유도체의 함량변화

김경업(Gyeong-Eup Kim),이용숙(Yong-Sook Lee),김성희(Sung-Hi Kim),정효숙(Hyo-Sook Cheong),이종호(Jong-Ho Lee) 한국식품영양과학회 1998 한국식품영양과학회지 Vol.27 No.5

우리나라 고유의 전동 발효식품으로 우리의 식생활에서 중요한 부식으로 이용되고 있는 배추, 열무, 갓김치를 제조하여 5℃와 20℃에서 저장하면서 염도 및 pH, 산도, 아스코르브산 함량, chlorophyll 및 그 유도체들의 함량변화를 조사하여 광증감작용이 큰 pheophorbide 생성과의 관계를 검토하였다. 염도는 배추김치가 3.7%, 열무김치가 3.6%, 갓김치가 3.5%로써 발효기간 동안 온도와 상관없이 큰 변화를 나타내지 않았다. pH는 발효가 진행됨에 따라 감소하였고 산도는 증가하였는데 특히, 발효 3일째에 pH의 감소와 산도의 증가가 두드러지게 나타났다. 김치의 발효 중 아스코르브산 함량은 지속적으로 감소하는 경향을 나타내었는데 5℃ 저장한 것에 비해 20℃ 저장한 것의 감소가 현저하였으며 그 중 갓김치의 아스코르브산 함량이 가장 높고 감소율도 낮은 반면, 열무김치의 감소율은 높게 나타났다. Chlorophyll 함량의 강소와 pheophytin과 pheophorbide 생성량의 증가는 발효 중 아스코르브산의 함량이 높게 유지되었던 갓김치에서 가장 낮게 나타났고 초기부터 급격한 감소를 보였던 열무김치에서 가장 높게 나타났다. Three kinds of kimchi using Chinese cabbage, leafy radish and mustard leaf were prepared by conventional method and stored at 5℃ or 20℃ for 13 days. During storage at both temperatures, changes of the amounts of salt and ascorbic acid, pH and total acidity were determined, and the relationship of the decomposition of chlorophylls with the production of their derivaties was studied. At both storage temperatures, salt concentration of Chinese cabbage kimchi(3.7%), leafy radish kimchi(3.6%), mustard leaf kimchi(3.5%) was relatively constant during the entire storage period. However, pH and total acidity were fluctuating with the remarkable changes during 3 days of storage. Ascorbic acid content was slowly decreased during the storage period and the decomposition rate of ascorbic acid was greater at 20℃ than 5℃. Among the kinds of kimchi tested, mustard leaf kimchi with the slow decomposition rate of ascorbic acid contained relatively high ascorbic acid content, while leafy radish kimchi contained the lowest content. At both storage temperatures, the production of pheophytin and pheophorbide from decomposition of chlorophyll was least in mustard leaf kimchi, but similar production rates in leafy radish and Chinese cabbage kimchi were observed.

비신생물성 질환에 대한 췌십이지장 절제술의 안정성 및 수술 후 삶의 질에 대한 평가

은영아(Young A Eun),김상걸(Sang Geol Kim),윤혁진(Hyuk Jin Yun),김종렬(Jong Yeol Kim),김갑철(Gab Chul Kim),염현규(Hyun Kyu Ryeom),김성희(Sung Hi Kim),황윤진(Yun Jin Hwang),윤영국(Young Kook Yun) 대한외과학회 2007 Annals of Surgical Treatment and Research(ASRT) Vol.73 No.1

Purpose: Pancreaticoduodenectomy for mass-like lesions that are suspicious of malignancy sometimes reveals only nonneoplastic disease, especially in those cases where adequate tissues for biopsy are unavailable. In this study, we evaluated the outcomes and quality of life (QOL) after pancreaticoduodenectomy for treating nonneoplastic disease. Methods: The clinical data of 28 patients who underwent pancreaticoduodenectomy for nonneoplatic disease and trauma from Jan. 1992 to Feb. 2006 were reviewed retrospectively. The QOL was evaluated using the FACT-Hep questionnaire. The patients who underwent laparoscopic cholecystectomy for benign gallbladder disease were utilized as the control group. Results: 13.8% (28/203) of all the pancreaticoduodenectomized patients had nonneoplatic disease and trauma. Male patients were predominant (25/28) and all the trauma patients were male. The mean age was 48 (23∼72) years old. The indications for surgery included lesions suspicious for malignancy (16 cases), pancreaticoduodenal artery aneurysm (1 case), and pancreatoduodenal injury (11 cases). The histologic findings of the nonneoplastic lesions revealed benign inflammation of the bile duct (6 cases), chronic pancreatitis (8 cases), pancreatic pseudocyst (1 case), and fibrosis of the Ampulla of Vater (1 case). No surgical mortality occurred. However, the trauma patients group had higher morbidity (72.7% Vs 23.5%, respectively, P=0.01) and a longer hospital stay (68.0 days Vs 32.6 days, respectively, P=0.02) after surgery compared to the nonneoplastic disease patient group. The QOL of the patient who underwent pancreaticoduodenectomy for nonneoplatic disease was not different from that of the control group. Conclusion: Since pancreaticoduodenectomy for nonneoplastic disease was safe and the QOL of the patients was acceptable, it should be performed more often when malignancies can not be excluded from the differential diagnosis.