치과용 자성재의 안정성 개선에 관한 연구 : I. 치과용 자성재의 전기화학적 부식에 대한 스퍼터링 도금의 효과 I. Effects of Sputtered Film Deposition on the Electrochemical Corrosion of Dental Magnetic Materials

고영무,최한철,정재헌,정효수,최성욱 대한치과기재학회 1999 대한치과재료학회지 Vol.26 No.4

In order to investigate the various properties of dental magnetic materials studies on corrosion behavior, decreasing rate of magnetic flux density, amount of elements released, mean average surface roughness values and the changing of mean surface microhardness values for dental application were done. To increasing the corrosion resistance of dental magnetic materials, surfaces of Sm-Co and Nd-Fe-B based magnetic materials were plated with gold(Au), platinum(Pt), titanium(Ti), chromium(Cr) and cobalt(Co), and then electrochemical corrosion test were performed in 4 kinds of electrolyte solution(0.9% NaCl, 1% lactic acid, 0.05% HCl and modified Fusayama's artificial saliva). The results were as follows: 1. In Sm-Co and Nd-Fe-B based magnetic materials, the pitting corrosion of experimental group was higher than that of the control group, the experimental group was less corrosive than control hroup. 2. The amount of elements released from experimental group was more significantly decreased than that of control group. 3. Decreasing rate of magnetic flux density of experimental groups was significantly lower than that of control group after corrosion test. 4. The mean average surface roughness value of one(Sm-Co based magnetic materials not plated) of the control group was much increased in modified Fusayama's artificial saliva after first corrosion but that of the other(Nd-Fe-B based magnetic materials not plated) was much increased in 0.05% HCl solution. 5. The decreasing rate of surface microhardness values of experimental groups were lower than that of control group after corrosion, 6. Intergranular corrosion started first from the grain boundary of the control group and they advanced gradually to general corrosion, and the pitting corrosion occurred locally at area of existing pits in experimental group.

경제학의 교양교육 방법론에 대한 연구

고정오, 김상욱 배재대학교 주시경교양교육연구소 2017 대학교양교육연구 Vol.2 No.1

대학교육에서 교양교육의 영역이 확대되고 중요성이 높아지면서 경제교육에 대한 인식도 변화하고 있으며 교양교육과정에서 차지하는 비중도 높아지고 있다. 본 논문에서는 기존의 교양교육과정에서 대학별로 운영하고 있는 경제교육 관련 영역과 교과목을 분석하고 이를 통해 몇 가지 특징들을 발견하였다. 첫째는 주요 대학의 교양교육에서 경제교육을 핵심 교양으로 중요시하고 있다는 점이다. 둘째는 경제교육에서의 경제교육을 담당하는 교과목에서 경제학의 일반화를 시도하고 있다. 셋째는 교양교육에서의 경제교육은 삶의 경제학을 추구하고 있다. 이를 통해 본 연구에서는 경제학의 교양교육 방법론으로 크게 네 가지를 제시하고 있다. 첫째는 생활경제학으로서의 경제교육이다. 둘째는 주제중심의 경제교육이다. 셋째는 실천중심의 경제교육이다. 그리고 넷째는 경제학자의 경제교육이다. 이들 네 가 지를 통해 경제학이 교양교육으로서의 역할을 담당할 수 있을 것으로 생각한다 The area of liberal education more and more important in university education, and the boundary is more expanding. The perception of the economics education is changed, the portion of the liberal education also more important. This paper analyzed the economic education system in colleges, and find three point. First, the university liberal education more important the economic education by the core liberal education. Second, the most university try to generalize the economic education. Third, the economic education pursue the life economics in liberal arts education. And this paper suggests the four methodology of the liberal education in economics. First is the life economics. Second is the theme-oriented education. Third is the practice-oriented education. Fourth is the economics education by the economist.

치과용 자성 어태치먼트 재료의 안정성 개선에 관한 연구 : II.질화티타늄 코팅이 치과용 자성재의 내식성에 미치는 영향 Ⅱ.Effect of TiN Coating on Corrosion Resistance of Dental Magnetic Materials

최한철,고영무,정재헌,신종연,김일선,최성욱,정효수 대한치과기재학회 1999 대한치과재료학회지 Vol.26 No.4

Dental magnetic materials have been applied to removable prosthetic appliances, maxillofacial prostheses, obturator and dental implant but they still have some problems such as low corrosion resistance in oral environments. To increase the corrosion resistance of dental magnetic materials, surfaces of Sm-Co and Nd-Fe-B based magnetic materials were plated with TiN and then electrochemical corrosion test were performed in 4 kinds of electrolyte solutions(0.9% NaCl. 1% lactic acid, 0.05% HCl and modified Fusayama's artificial saliva). From this study, corrosion behavior, amount of elements released, mean average surface roughness values and the changing of mean surface microhardness values were measured comparing with control group of non-sputtered plating magnetic materials. The results were as follows: 1. TiN layer coated on magnet grows into preferred direction with lamellar structure and its thickness is 3.0㎛. 2. Sm-Co base magnetic materials coated with TiN have good corrosion resistance in 1% lactic acid and their pitting corrosion can not be seen. 3. Nd-Fe-B base magnetic materials coated with TiN showed good tendency of corrosion resistance in 0.05% HCl solution. 4. The amount of elements released from both Sm-Co and Nd-Fe-B base magnetic materials coated with TiN were more significantly decreased than that of uncoated magnetic materials. 5. The mean surface roughness values of both Sm-Co and Nd-Fe-B base magnetic materials coated with TiN were smooth than that of uncoated magnetic materials after corrosion test. 6. The decreasing rate of microhardness of both Sm-Co and Nd-Fe-B base magnetic materials coated with TiN were lower than that of uncoated magnetic materials after corrosion test. 7. Dental magnetic materials coated with TiN produced various corrosion products such as TiO, TiO₂, Ti₂O₃on the surface and resulted in better corrosion resistance than uncoated magnetic materials. In conclusion, it is considered that the corrosion problem of dental magnetic materials could be solved to some extent by EB-PVD with TiN on the surface of dental magnetic materials.

골수강내 금속정 및 나사못 맞물림을 이용한 경골의 치료

최창혁,권굉우,김신근,이상욱,강창진 대구효성카톨릭대학교 1997 연구논문집 Vol.56 No.2

Fracture of the tibial shaft is the most common among the long bone fractures, and it is difficult to treat because of a high incidence of delayed union, nonunion and malunion. Interlocking Intramedullary mailing is considered to be valuable method in treating long bone fracture such as tibial fracture these days because it enables rigid fixation, early joint motion exercise and weight bearing. Between April 1993 and March 1997, we treated 63 cases of tibia fractures with interlocking intramedullary nailing. The results were as follows: 1. Among the 63 cases, 51 cases were closed fractures and 12 cases were open fractures. 2. Static interlocking nailing was done in all cases and dynamization was done in 7 cases in postoperative 13 weeks. 3. Average union time was 19.9 weeks, 19 weeks with closed tibia fracture and 2.4 weeks with open tibia fracture. According to fracture site, 22 weeks with proximal tibia fracture, 19.2 weeks with mid-tibia fracture and 21.4 weeks with distal tibia fracture. According to the Winquist-Hansen classification, Type I was 19.8 weeks, Type Ⅱ was 20.4 weeks, Type Ⅲ was 22 weeks and Type Ⅳ was 26 weeks. 4. Weight bearing was started at the time of subsidence of pain and tenderness of the fracture site, 11.5 weeks with closed fracture and 12.3 weeks with open fracture. 5. According to the functional result of Klemm and Borner, 44 cases were excellent, 9 cases were good, 7 cases were fair and 3 cases were poor.

驅動部 動特性을 高慮한 可變構造 制御 알고리듬

강익호,김정욱,신휘범,이정훈,고상호 慶尙大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.13 No.-

In this paper, the dynamics of actuators for generating the input of plants is considered in a design of the variable structure systems. While the input for plants is usually implemented by means of a certain actuator, the actuator dynamics is not incorporated in most of the VSS researches until now. The control algorithm of a VSS incorporating actuator dynamics is presented. and the simulation is given the usefulness of the algorithms.

3분 및 4분 상완골근위부 골절에서의 외반형 및 내반형에 따른 임상적 비교

최창혁,권굉우,김신근,이상욱,신동규,이승진 대한골절학회 2002 대한골절학회지 Vol.15 No.4

목 적 : 수술적으로 치료한 3분, 4분 상완골 근위부 골절을 외반형과 내반형으로 재분류하여 임상적 결과를 비교하고자 하였다. 대상 및 방법 : Neer 분류상 3분, 4분 상완골근위부 골절로 분류된 21례에 대해 수술적 치료를 시행하고 12개월 이상 추시된 증례를 대상으로, 골절부위의 각형성, 상완골두의 방향성, 그리고 우세 전위결절의 양상에 따라 외반형과 내반형으로 재분류하여 UCLA shoulder rating scale에 따른 기능적 평가를 시행하였다. 결 과 : 단순 방사선 소견을 기준으로 Neer의 3, 4분 상완골 근위부골절을 외반형과 내반형 및 각각의 아형(subtype)으로 분류할 수 있었다. 견관절 반치환술을 시술한 2례를 제외하고 분석한 각 그룹의 UCLA 기능적 평가는 외반형에서 양호 이상의 결과가 9례중 8례(89%), 내반형에서 10례중 4례(40%)로 외반형에서 더 우수한 임상적 경과를 보였다. 결 론 : 상완골 근위부 골절에서 골두의 방향성은 골절의 각형성 및 우세 전위결절의 양상과 높은 상관관계를 가졌으며, 내반형의 경우 혈행과 신경장애가 좀더 빈번하고 예후도 불량한 것으로 나타났고, 이러한 경우 수술시 도달 방법, 연부조직 상태에 대한 평가가 더욱 신중하게 고려되어야 할 것으로 생각되었다. Purpose : We reclassified three-and four-part proximal humerus fracture by Neer's classification into valgus & varus type, and compared the results of these groups. Materials & methods : 21 cases classified as three- and four-part fracture in Neer's classifiation were treated surgically and followed for 12 months. We reclassified the 21 cases vlagus and varus type fractures, according to angulation of fractures, facing of humeral head, and dominant displaced tuberosity. Functional evaluation was done by UCLA shoulder rating scale. Results : Neer's three- and four-part proximal humerus fractures could be reclassified based on angulation, facing of humeral head, and dominant tuberosity displacement. The functional results according to UCLA shoulder rating scale were good or excellent in 8 of 9 cases of valgus type(89%), and at 4 in cases of varus type(40%). The clinical result of the valgus type was better than that of the varus type. Conclusion : Based on reclassification system of proximal humerus fractures, clinical results and radiographic findings including angulation, facing of head and domonant tuberosity displacement showed close relationship. Neurovascular complication were more frequent in the varus type. Therefore, careful evaluation including surgical approach and soft tissue status should be considered in the varus type of complex proximal humerus fracture.

Azithromycin으로 치료한 임신 중 쓰쓰가무시병 1예

김광석,최진욱,서호종,김기훈,박성호,서광섭,고성만,김순혜,김호정 대한감염학회 2001 감염 Vol.33 No.5

We report a case of tsutsugamushi disease in a 26 year-old pregnant woman who was treated with azithromycin. Her gestation period was 27 weeks and she admitted with fever, rash, and eschar on the right shoulder. Currently recommended medications for the treatment of scrub typhus are doxycycline or chloramphenicol. But, these drugs are class D drugs according to the U.S. Food and Drug Administration (FDA) Fetal Risk Summary, so they couldn't be used to treat pregnant women. Recently, a few case reports suggested that azithromycin, a relatively new macrolide antibiotic, was effective and safe for the treatment of scrub typhus in pregnant women. And, there is no evidence that azithromycin causes harmful effects to the developing fetus or to children. On the basis of current in vivo test that confirms the effectiveness of azithromycin, it may be the drug of choice for the treatment of scrub typhus in pregnant women and children. (Korean J Infect Dis 33:380-382, 2001)

셀레콕시브 및 그 합성유도체들의 항암활성 스크리닝

박정란,강진형,구효정,노지영,류형철,박상욱,고동현,조일환,이주영,황다니엘,김인경 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.2

Selective COX (cyclooxygenase)-2 inhibitors including celecoxib have been shown to induce apoptosis and cell cycle changes in various tumor cells. New inhibitors are recently being developed as chemomodulating agents. We evaluated celecoxib and screened 150 synthetic compounds for anti-proliferative activities in vitro. Effects of celecoxib on COX activity, cell growth, cell cycle distribution, and apoptosis induction were determined in A549 COX-2 overexpressing human non-small cell lung cancer (NSCLC) cells. The COX inhibition of celecoxib increased with concentration up to 82% at 1μM after 24 hr exposure. Forty μM and 50μM of celecoxib induce G_1 arrest, and TUNEL-positive apoptotic cells, respectively. Among 150 compounds, several compounds were selected for having greater COX-2 inhibitory activity and higher selectivity than celecoxib with growth inhibitory activity. Celecoxib showed concentration-dependent COX inhibitory activity, and ability to induce cell cycle arrest and apoptosis in human NSCLC cells in vitro. Among synthetic analogues screened, several compounds showed promising in vitro activity as COX-2 inhibitory anticancer agents, which warrant further evaluation in vitro and in vivo.

A Predictive Method for the Femoral Head Necrosis by the Observation of the Bleeding from the Cannulated Screw in Patients of the Femoral Neck Fractures

Sang-Wook Lee(이상욱),Myung-Rae Cho(조명래),Byoung-Kwan Lee(이병관),Sang-Bong Ko(고상봉),Dong-Kyu Shin(신동규),Koing-Woo Kwon(권굉우) 대한정형외과학회 2004 대한정형외과학회지 Vol.39 No.5

목적: 대퇴 경부 골절 환자에서 수술시 고정을 위해 사용하는 유관 나사를 이용하여 향후 대퇴 골두 골 괴사의 예측 방법에 대하여 조사하였다. 대상 및 방법: 1999년 3월부터 2001년 2월까지 44명을 대상으로 최소 25개월 이상 추시 관찰하였으며, 평균 나이는 51세(18-76세)였다. 근위부에 삽입된 유관 나사의 두부에 있는 관으로부터 출혈 유무를 관찰하였는데, 출혈군은 38예, 비 출혈군은 6예였다. 추시에서 대퇴 골두 골 괴사는 단순 방사선 사진으로 판독하였다. 두 군에서 유관나사 부위의 출혈 유무와 무혈성 괴사의 발생 관계에 있어 민감성, 정확성, 양성 예측도, 음성 예측도를 조사하였다. 결과: 대퇴 골두 골 괴사는 7예(16%)에서 발생하였다. 출혈군은 38예 중 1예(2.6%), 비 출혈군은 6예 모두에서 대퇴 골두골 괴사가 발생하였다. 비 출혈군과 골두 골 괴사의 관계에서는 민감도 86%, 정확도 100%, 양성 예측도 100%, 음성 예측도가 97%였다. 결론: 대퇴 경부 골절 환자에서 추후 발생할 수 있는 대퇴 골두 골 괴사에 대한 예측 방법으로 수술 중 유관 나사의 두부관 출혈 유무가 단순하면서 유용한 방법으로 판단된다. Purpose: The aim of this study was to examine the validity of using cannulated screws as a method for predicting avascular necrosis of the femoral head after a fixation of fractures in patients with femoral neck fractures. Materials and Methods: Between March 1999 and January 2001, 44 patients with a femoral neck fracture that had been fixed with cannulated screws were enrolled in this study. The follow up period was more than 25 months and the mean age of the patients was 51 years (range, 18 to 76 year). Blood drainage in the holes of the screw head was checked. There were 38 cases in the bleeding group, and 6 cases in the non-bleeding group. The development of head necrosis was evaluated using plain radiography. The validity of the relationship between the two groups and head necrosis was evaluated by the sensitivity, specificity, the positive predictive value, and the negative predictive value. Results: An avascular necrosis of the femoral head developed in 7 cases (16%). Only one of the 38 patients in the bleeding group developed head necrosis (2.6%). However, all those in the non-bleeding group developed head necrosis (100%). The sensitivity was 86%, the specificity was 100%, the positive predictive value was 100%, and the negative predictive value was 97%. Conclusion: Bleeding from holes in the cannulated screws is a simple and accurate perfusion assessment for predicting the development of an avascular necrosis of the femoral head after a femoral neck fracture.

Clinical Analysis of Femur Shaft Insufficiency Fractures

Sang-Bong Ko,Sang-Wook Lee,Chang-Min Park,Sang-Hwa Lee 대한정형외과학회 2012 Clinics in Orthopedic Surgery Vol.4 No.3

Background: To characterize the recently issued femur shaft insufficiency fracture in terms of a patient’s own epidemiological status. Methods: Fourteen patients were treated for insufficiency fracture from July 2002 to June 2008, excluding cases including the risk factors of insufficiency fracture. All patients were female, and their mean age was 75.6 years (range, 65 to 89 years). The mean follow-up period was 50.6 months (range, 14 to 86 months). Results: The mean body weight of the Koreans in the same age group was 58.1 ± 9.7 kg, and the mean height was 155.5 ± 8.8 cm. The mean body weight of our insufficiency fracture patients was 45.7 kg and it was statistically significantly lower than that of the Koreans in the same age group (p < 0.001). The mean height was 147.3 cm and it was significantly shorter than the mean height of the Koreans in the same age group (p = 0.002). In regard to menopausal time, the mean menopausal time of the Koreans was 48.0 ± 4.2 years, it was 44 years in our study, as menopause occurred statistically significantly earlier (p = 0.017). The patients with insufficiency fracture showed statistically lower weight, shorter stature and an earlier menopausal period than that of the general population. Conclusions: In early menopausal, underweight, and short patients prescribed osteoporosis medication for an extended period of time, if predromal symptom is present, it is necessary to suspect insufficiency fracture of the femur.