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      • Aflatoxin B₁의 多量投與에 依한 白鼠肝中毒病變과 生化學的 所見과의 相關關係에 關한 實驗的 硏究

        鄭孝洙,白承龍 고려대학교 의과대학 1981 고려대 의대 잡지 Vol.18 No.1

        Aflatoxin, a substituted lactone, is a metabolite of certain strain of Aspergillus flavus. It may induce marked hepatic damage in many species of mammals, and periportal necrosis and bile duct proliferation have been known to occor frequently in acute poisoning. The author performed blood chemistry studies to clarify the effect of aflatoxin B₁ on the liver of male albino rats weighing about 200gm. Aflatoxin B₁ dissolved with dimethyl sulfoxide was injected singly into the peritoneum, 1㎎/㎏ to 70 rats. Each experimental group was made of 5 rats; the rats were sacrificed at 1 day intervals from the first to the sixth day after injection. Blood glucose, protein, cholesrerol, bilirubin and the serum activities of glutamic oxalacetic transaminase, glutamic pyruvic transaminase, sorbitol dehydrogenase, gamma-glutamyl transpeptidase and alkaline phosphatase were determined in each rat. The results obtained were as follows: 1. The hepatic changes included acidophilic degeneration, vacuolar changes, nuclear pyknosis and focal and periportal necrosis on hematoxylin-eosin stain; these changes seemed to be dose-dependent. 2. Blood glucose levels were increased above normal levels, but statistically were not significant. 3. Serum protein revealed decrease of albumin and increase of globulin and those changes were more marked in high dose injection group. 4. Serum cholesterol and bilirubin showed no variation from normal levels. 5. The activities of the serum transaminases were increased and revealed peaks on the 3rd and 5th day after injection of 1㎎/㎏ and 6㎎/㎏ of aflatoxin B₁ respectively. 6. The activity of serum sorbitol dehydrogenase showed an increase from the first day after aflatoxin injection; high enzyme levels persisted thereafter. 7. The activities of serum gamma-glutamyl transpeptidase and alkaline phosphatase were increased to a moderate degree. Because of these findings, the author believes that increased servm enzyme activities are maintained even beyond the time when histologic findings have almost nearly returned to normal such that the determination of the levels of sorbitol dehydrogenase and gamma glutamyl transpeptidase may be clinically applicable in the estimation of the degree of hepatic damage.

      • KCI등재

        Manufacturing of Cs3Sb Photocathode in Atmospheric Conditions

        정효수 한국전기전자재료학회 2014 전기전자재료학회논문지 Vol.27 No.10

        Cs3Sb photocathode was formed by newly developed process and successive in-situ lightingdevices were fabricated in a process chamber. R, G, and B phosphors were applied on the anode plate,respectively. Major parameters such as brightness, power consumption, and efficacy were measured. Thewavelength of LED excitation source was 450 nm. Both high power and low power modes were appliedin the measurement. Measurement values were clearly differentiated by the voltage application modes. The measured values of each parameter was good enough to be applied for general lighting source. Theresults showed that Cs3Sb photocathode formed in atmospheric conditions was functioning as good as thephotocathode formed in UHV conditions, and thus it could be applied to advanced lighting devices.

      • Luminous Properties of Planar Lighting Devices Using Cs3Sb Photocathodes

        정효수 水原大學校 2015 論文集 Vol.29 No.-

        The Cs3Sbphotocathodewasformedby non-vacuum process technology and successive in-situ photocathode vacuum device fabrication was carried out in a process chamber. Performance test of the device was followed. Light emission from the devices was induced by photoemitted electrons, accelerated by an anode electric field that was shielded from the photoemitter surface. The luminescent characteristics of the devices were investigated by measuring the optical parameters as functions of applied anode voltages. The results showed the possibility to produce a more directable and easily controllable stream of light. These make the devices suitable for a variety of planar lighting applications.

      • KCI등재

        A Study on Operating Lifetime of Cs3Sb Emitters in Panel Device Applications

        정효수 한국전기전자재료학회 2017 Transactions on Electrical and Electronic Material Vol.18 No.3

        Non-vacuum processing technology was used to produce Cs3Sb photocathodes on substrates and fabricate insitupanel devices. Electrical properties of these panel devices were characterized by measuring anode current andcharge dose as functions of devices operation time. An excitation light source with a 475 nm wavelength was usedfor photocathodes. Results showed that emission properties of these photocathode emitters depended heavily onthe vacuum level of these devices and that Cs3Sb flat emitters had the potential of operating for a long lifetime withstable electron emission characteristics via re-cesiation process in the panel device. These features make Cs3Sbphotocathodes suitable as flat emitters in panel device applications.

      • KCI등재

        Electrical Characteristics of Flat Cesium Antimonide Photocathode Emitters in Panel Devices

        정효수 한국전기전자재료학회 2016 Transactions on Electrical and Electronic Material Vol.17 No.5

        The Cs3Sb photocathode was formed by non-vacuum process technology. An in-situ vacuum device was fabricatedsuccessively with flat cesium antimonide photocathode emitters fabricated in a process chamber. The electricalproperties of the device were characterized. Electron emission from the devices was induced by photoemittedelectrons, which were accelerated by an anode electric field that was shielded from the photoemitter surface. Theelectrical characteristics of the devices were investigated by measuring the anode current as a function of deviceoperation times with respect to applied anode voltages. Planar blue LED light with a 450 nm wavelength was used asan excitation source. The results showed that the cesium antimonide photocathode emitter has the potential of longlifetime with stable electron emission characteristics in panel devices. These features demonstrate that the cesiumantimony photocathodes produced by non-vacuum processing technology is suitable for flat cathodes in panel deviceapplications.

      • KCI등재

        상압에서 제조한 포토캐소드의 전자방출 특성에 관한 연구

        정효수,Jeong, Hyo-Soo 한국전기전자재료학회 2014 전기전자재료학회논문지 Vol.27 No.5

        Photoemission is a process in which photons are converted into free electrons. Photocathodes are the typical materials for the process. They emit electrons when a light is irradiated upon. The traditional method of manufacturing photocathodes is complicated, requires specialized equipment, and is limited very small sized samples. $Cs_3Sb$ photocathode was formed on a substrate in $N_2$ atmospheric conditions. The photocathode formation was a gas phase reaction with the substrate. Vacuum devices were made to test electron emission characteristics of the formed photocathode. Visible light of wavelength 475 nm was used for the primary light source. The results showed high current density and long term stability of the photoelectron emission.

      • KCI등재

        Manufacturing of a Planar Lighting Device Using Cs3Sb Photocathode Emitters

        정효수 한국전기전자재료학회 2016 Transactions on Electrical and Electronic Material Vol.17 No.1

        The Cs3Sb photocathode was formed by non-vacuum process technology and successive in-situ photocathode vacuum device fabrication carried out in a process chamber. Performance testing of the device was followed. Light emission from the devices was induced by photoemitted electrons, which were accelerated by an anode electric field that was shielded from the photoemitter surface. The luminescent characteristics of the devices were investigated by measuring the optical parameters as functions of the applied anode voltages. The results showed that this approach could produce a more easily directed and controlled stream of light. These features make these devices suitable for a variety of planar lighting applications.

      • KCI등재

        Fabrication of a Planar UV Lighting Device Utilizing Cs3Sb Photocathode Emitters

        정효수 한국물리학회 2017 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.71 No.12

        Planar ultraviolet (UV) light sources with uniform intensity are ideal for UV treatments. A newly conceived planar UV lighting device utilizing Cs3Sb mono-alkali antimonide photocathodes as flat electron emitters is presented and analyzed here. The design concept involves a panel device that utilizes photocathodes operated in a reflection mode with an external excitation light source. The excitation light source is in the blue visible light range. Commercially available UV phosphors are used as a light source of desirable UV wavelengths. The light emission characteristics of the device are investigated by measuring the optical parameters as function of applied anode voltage. The UV light emission shows that cold UV light with the spectral characteristics of near-monochromatic distribution are most effective. It also demonstrates that the UV intensity is sufficient for the UV treatment. More importantly, the planar UV lighting device is mercury free. These make them suitable for all UV applications.

      • Optical Properties of Planar Lighting

        정효수 水原大學校 2016 論文集 Vol.30 No.-

        This paper presents a concept for a planar light source utilizing Cs3Sb as flat electron emitters. The design concept of the devices with a diode structure was that the photocathodes were to be operated in a reflective mode. Commercially available P-22 phosphors were used as a light source of desirable wavelengths. Light emission from the devices was induced by photoemitted electrons, accelerated by an anode electric field that was shielded from the photoemitter surface. The optical properties of the devices were investigated by measuring the optical parameters as functions of applied anode voltages. The results showed the possibility to produce a more directable and easily controllable stream of light. These make the devices suitable for a variety of planar lighting applications.

      • Fabrication of a planar UV lighting device utilizing Cs3Sb emitters

        정효수 水原大學校 2017 論文集 Vol.31 No.-

        Planar UV light sources with uniform intensity are ideal for UV treatments. A newly conceived planar UV lighting device utilizing Cs3Sb mono-alkali antimonide photocathodes as flat electron emitters is here presented and analyzed. The design concept involves a panel device that utilizes photocathodes operated in a reflection mode with an external excitation light source. The excitation light source is in the blue visible light range. Commercially available UV phosphors are used as a light source of desirable UV wavelengths. The light emission characteristics of the device are investigated by measuring the optical parameters as functions of applied anode voltages. The UV light emission shows that cold UV light with the spectral characteristics of near-monochromatic distribution are most effective. It also demonstrates that the UV intensity is sufficient for the UV treatment. More importantly, the planar UV lighting device is mercury free. These make them suitable for all UV applications.

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