폴록사머 및 프로필렌글리콜을 이용한 클로트리마졸 고형 좌제의 물리화학적 특성

현경희,오유경,김정애,공경환,김지현,양준호,배명수,김호동,이종달,장현욱,용철순,최한곤 한국약제학회 2005 Journal of Pharmaceutical Investigation Vol.35 No.2

To develop a clotrimazole-loaded solid suppository with poloxamer and propylene glycol, the melting points of various formulations composed of poloxamer 188 (P 188) and propylene glycol were investigated. The dissolution study of clotrimazole delivered by the suppository composed of P 188 and propylene glycol was performed. The mixtures composed of P 188 and propylene glycol were homogeneous. Propylene glycol affected the melting points of poloxamer mixtures. In particular, the mixture [P 188/propylene glycol (70/30%)] with the melting point of about 32°C was a solid form at room temperature and instantly melted at physiological temperature. Furthermore, propylene glycol affected greatly the dissolution rates of clotrimazole from the suppository. Dissolution mechanism analysis showed the dissolution of clotrimazole was proportional to the time. Our results indicated that the solid suppository with P 188 and propylene glycol would be a candidate of rectal dosage form for clotrimazole.

한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

어린이 도서관의 전인적 치유환경에 관한 연구 : 루돌프 슈타이너의 이론을 중심으로

김혜연,김광호,진달래 한국의료복지시설학회 2007 의료·복지 건축 Vol.13 No.3

동적계획모형을 이용한 근무형태 결정

김중순,안봉근,손달호 한국경영과학회 2003 經營 科學 Vol.20 No.2

In this paper, we applied dynamic programming to determining work schedule type. In dynamic programming formulation. each day during a planning horizon represents a stage for which a decision Is made. The alternatives are given by work schedule types that combine regular time, overtime. additional shift, and so on. In this case, their associated return function is labor cost. The state is defined as the amount of work time allocated to stage 1, stage 2, …, and current stage. A case study for a real manufacturing company was performed to apply dynamic programming to scheduling daily work hours during a week. The case study showed that total cost of our solution derived from dynamic programming decreased by about 6% as compared with the solution obtained from the previous method.

인터넷뱅킹의 성공요인에 대한 실증적 연구

김현민,손달호 啓明大學校 産業經營硏究所 2003 經營經濟 Vol.36 No.2

Currently, one of the words mentioned most frequently on the newspapers and other media may be the internet. Internet business such as "on-line service", "electronic commerce", "internet shopping mall", "internet banking" is not too exaggerated to lead the global economy. In this age of cyber community. those who try to develop and innovate in it than to stay will stride in this circumstances. Internet banking may not be exception. Thus, it should be very important to preview the effects of internet banking on the financial industry and thereby, explore effective counter-measures. However, there is scarcely done for the empirical study to the determinants of the internet banking. Considering with this circumstances, this study tried to find the effect of the determinants of internet banking. The result showed that the effect of the determinants was not consistent depend on the type of the variable. However, further study was required to verify the consistent result of the determinants.

RC Arch Deck Development and Performance Evaluation for Enhanced Deck Width

Dal?Hun Yang,Min?Jae Kwon,Gi?Ha Eom,Jang?Ho Jay Kim 한국콘크리트학회 2018 International Journal of Concrete Structures and M Vol.12 No.6

Due to extreme business competitions in bridge construction industries, the cost reduction became the most important issue in winning a contract bidding. The largest bridge construction cost saving can be obtained by using precasted construction method and by reducing required number of girders, columns, and decks in the bridge system. Therefore, an precasted arch deck system is proposed to widen the lateral span of the deck, which can result in reducing the number of required I-type PSC girders for construction cost saving. A usual lateral width of a flat deck is 1.5–2.0 m, but the width of arch deck is 2.5 m, an increase of 25–60%. Therefore, for a PSC girder bridge with a total width 10 m, a number of required girders needed for ordinary flat RC deck and arch deck is 5 and 4, respectively. This means that one less girder can be required, which means that 20% of girder construction cost can be achieved by using arch deck over ordinary flat deck. In this study, precasted RC arch deck is developed and manufactured to evaluate structural performance of the deck. The study results showed that arch deck has performance exceeding ordinary flat deck and can be used as alternative decks for precasted PSC I-girder bridge construction. The study results are discussed in detail in the paper.

ID-GC/MS에 의한 쌀 중의 잔류농약 인증표준물질

김유곤,김달호,백병천,이우범 國立 麗水大學校 환경문제硏究所 2001 環境硏究論文集 Vol.4 No.-

The CRM used in evaluation of effectiveness, calibration or analysis equipment when you analyse in material of rice powder or similar matrix. Analytical items were γ-HCH, p,p'-DDE, endosulfan-2, samples of achieved pertreatment analized each component indivisually. Control mode of MS used selected ion monitering(SIM). GC is 6890GC of Agilent Technology company and MS is JMS 700 of Jeol company. MS operating condition was Electron impact ionization with 70eV. 300A, GC operating condition was Column : Rtx-5MS 30m*0.25m ID*0.25um, Oven Temp 90℃(3min)-20℃/min-280℃(2min), Injection port 250℃, splitless, Carrier Gas He with 1mL/min. Water contents was 12.534% and dry mass correction factor 1.143. CRM certified values of the experiment result were p,p'-DDE 0.165±0.011,mg/kg, γ-HCH 0.0129±0.0011mg/kg, endosulfan-2 0.0216±0.0027mg/kg. The numbers following the symbol ± are the numerical values of expanded uncertainties, U=ku_(c) of measurement values preceding the symbol. The level of confidence for the expanded uncertainties are 96% with k=2.

사진 필름상의 할로겐은 입자가 레이저광 회절 무늬에 미치는 영향에 관한 이론적 고찰

강석호,김달우 嶺南大學校 工業技術硏究所 1982 연구보고 Vol.10 No.1

It was theoretically considered whether the silver-halide grains remained on the slide film on which round or rectangular particles as particle sample were photographed affect the laser diffraction pattern intensity It is confirmed that grain size of 0.7 to 2.3㎛ on the film does not affect the pattern analysis of the particle images diffracted with laser light whose wavelength is 0.6328㎛. In theory, the distances between adjacent grains affects the pattern intensity, but this effect can be also negligible, if the distance is not shorter than 10 times of the wavelength of the laser light.

분산 환경에서 Agent를 이용한 LCL 화물 정보 시스템

이달상,김태화,반상우,전성호 한국경영과학회 2001 한국경영과학회 학술대회논문집 Vol.- No.1(1)

LCL은 컨테이너에 화물을 적재할 때 한 화주가 컨테이너의 공간을 전부 사용하는 FCL과 달리 여러 명의 화주가 각자의 화물을 한 컨테이너에 적 재하는 방식을 말한다. 기존의 LCL 업무에서는 화주가 운송할 화물이 하나의 컨테이너 전체를 사용하려하지 않을 때 LCL Cargo를 선박회사에 신청하고 선박회사는 이러한 업무를 대행해 주는 Forward에게 의뢰하게되고 Forward는 컨테이너의 남는 CBM(cubic met er )을 채울 화물의 화주들을 모집하는 형태와 화주가 화물을 적재하고 남은 CBM이 있으면 선박회사가 직접 Forward에 의뢰하여 화주들을 모집하는 형태가 있다. 본 논문에서는 이들을 웹 상에서 서비스하는 LCL 화물 정보시스템을 제안한다. 이 시스템은 화주가 LCL 화물 선적을 신청하게되면 선주가 선적 할 컨테이너에 대한 모든 정보와 적재된 화물의 정보 등을 실시간으로 제공하여 이에 다른 화주들이 자신의 LCL 선적할 화물에 대한 정보를 제공하게 되고 선주는 이런 정보들을 바탕으로 컨테이너에 LCL 선적할 화주를 결정하는 방식과 화주가 LCL 화물 선적 신청을 위해 화물에 대한 정보를 미리 제공한 정보를 바탕으로 하여 화주를 결정하는 방식 등이 제공된다. 이러한 방식들에 의해 화주를 선정하기 위해서는 제공되는 정보들을 바탕으로 한 적절한 정책이 필요하다. 이 정책은 시스템내의 Agent들에 의해서 이루어지며 이 Agent들은 정책을 바탕으로 화주를 결정하는 것뿐만 아니라, 인터페이스를 통하여 제공되는 정보를 모으는 역할, 그리고 데이터베이스로부터 정보를 가져오고, 새로운 정보를 관리하는 역할 등을 수행하도록 한다. 이러한 일들을 전담하는 Agent를 각각 두어 서로간의 통신을 통한 협력 구조를 이루도록 한다. 그리고 데이터베이스의 접근에 있어서도 CORBA를 이용하여 이 기종의 시스템들에 분산된 데이터베이스에 쉽게 접근할 수 있도록 하여 보다 많은 정보를 바탕으로 시스템을 운영할 수 있다.

감성적 오피스 랜드스케이프를 통한 치유적 사무공간에 관한 연구 : 막스 뤼셔의 심리치유이론을 중심으로

진달래,김광호,김혜연 한국의료복지시설학회 2007 의료·복지 건축 Vol.13 No.3