Poster Session : PS 0831 ; Upper GI Tract : Clinical Factors to Predict Angiographically Detectable Non-Variceal Upper Gastrointestinal Bleeding in Patients Refractory to Endoscopic Treatment

( Tae Hwan Ha ),( Tae Hoon Oh ),( Sung In Yu ),( Min Kim ),( Jong Wook Kim ),( Won Ki Bae ),( Jae Hyung Kim ),( Seung Suk Baek ),( Mi Jin Ryu ),( Ye Na Choi ),( Ji Young Park ),( Eileen L Yoon ),( Tae 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Non-variceal upper GI bleeding (NVUGIB) is a common medical problem that has signifi cant association with morbidity and mortality. Angiographic detection and subsequent transarterial embolization (TAE) is a primary treatment option when medical and endoscopic treatments fail. We investigated clinical factors that could affect the success of the angiographic detection and prognosis after TAE in patients with NVUGIB refractory to endoscopic therapy. Methods: A retrospective analysis of the clinical data was done in patients with failed endoscopic treatment who underwent angiography for the treatment of acute NVUGIB between May 2002 and May 2013. Patients were divided into detection or non-detection groups according to the presence of bleeding stigmata in angiographic fi nding. Rebleeding defi ned as subsequent bleeding event within 7 days and mortality within 30days were analyzed as outcome parameters after TAE following detection in angiography. Results: A total 45 patients 37 (male, mean age, 65.9±14.9 years) were analyzed and classifi ed as a detection group (n=25, 55.5%) and non-detection group (n=20, 44.6%). Peptic ulcers were the most common cause of refractory NVUGIB. Larger transfusion amount (5.7±3.9 unit vs. 3.5±2.8 unit; P=0.03), prolonged aPTT level (34.2±17.3 sec vs. 21.8±13.8 sec; P=0.01) and short time interval between last endoscopy and angiography (17.5±25.9 hours vs. 34.3±59.5 hours; P=0.04) were found to be signifi cant factors for predicting angiographic detection. TAE was performed in all patients detected in angiography. Rebleeding (44%) was significantly associated with higher Rockall score (8.3±1.5 vs. 6.6±2.4; P=0.046) and mortality (12%) was signifi cantly associated with higher Rockall score (9.3±0.6 vs. 7.1±2.2; P=0.002) and higher level of BUN (55.3±47.4 vs. 27.6±17.4; P=0.01). Conclusions: Clinical characteristics associated with angiographic detection in patients with NVUGIB refractory to endoscopic therapy were severe bleeding, bleeding tendency and early angiographic intervention. The Rockall score is useful parameter for predicting rebleeding and mortality after TAE.

축구선수의 Detraining과 Retraining이 혈청지질 및 호르몬농도에 미치는 영향

정정화,박재현,채종훈,성혜련,황지인,윤미숙,노금선,윤종관,윤영학,노순덕,정경숙,박일규,김은희,박현태,박상갑 대한스포츠의학회 1999 대한스포츠의학회지 Vol.17 No.1

The purpose of this study was to investigate the effects of detraining and retraining on serum lipid and hormones in soccer players. Subjects were seven male high-school soccer players. V˙O_2max was determined for each subjects by administering a treadmill test(initial speed: 90m/min, grade: 5%, increasing speed per 3 min: 30m/min). Serum lipid(T-C, TG, HDL-C LDL-C) and hormones(epinephrine, norepinephrine, growth hormones, cortisol) were assayed pre and post detraining in 10, 20, 30 days after retraining. The repeated ANOVA was used to determine significant differences. The 0.05 level of significance was as critical level for the study. The results of the study were as follows: 1. V˙O_2max(ml/min) were 3576.3±204.2ml/min pre detraining, 3234.1±198.9 ml/min post detraining. There are significant(p<.05) difference between pre and post detraining. In 10, 20, 30 days after retraining, V˙O_2max(ml/min) were 3601.4±170.9 ml/min. There were significantly(p<.05) increased in retraining periods. 2. V˙O_2max(ml/kg/min) were significantly(p<.05) decreased from 62.3±2.9 ml/kg/min to 55.9±4.7 ml/kg/min in detraining. In 10, 20, 30 days after retraining, V˙O_2max(ml/kg/min) were 62.4±3.4ml/kg/min, 62.7±2.3ml.kg/min, 67.3±7.2ml/kg/min respectively. There were significantly(p<.05) increased in retraining periods. 3. T-C were significantly (p<.05) increased from 166.6±8.5mg/dl to 175.3±10.3 mg/dl in detraining. In 10, 20, 30 days after retraining, T-C were 160.1± 3.2mg/dl, 156.7±3.7mg/dl, 140.3±9.0mg/dl. There were significantly(p<.05) decreased in retraining periods. 4. HDL-C were 61.4±6.6mg/di pre detraining, 5.3±6.6mg/dl post detraining. There are significant(p<.05) difference between pre and post detraining. In 10, 20, 30 days after retraining, HDL-C were 56.9±7.1mg/dl, 56.4±9.2mg/dl, 57.7±9.1mg/dl respectively. There were no significant difference in retraining periods. 5. The hormones(epinephrine. norepinephrine, growth hormone, cortisol) were changed as same patterns. Epinephrine were 26.0±7.0[g/ml pre detraining, 24.6±3.2pg/ml post detraining. In 10, 20, 30 days after retraining, epinephrine were 26.9±5.6pg/ml, 30.6±6.2pg/ml, 29.4±5.6pg/ml respectively. There were no significant difference in retraining periods. In conclusion, HDL-C, epinephrine, norepinephrine, growth hormone and cortisol were decreased, T-C, LDL-C and TG were increased in detraining. But HDL-C, epinephrine, norepinephrine, growth hormone and cortisol were increased, T-C, LDL-C and TG were decreased in retraining.

청심연자탕(淸心蓮子湯)으로 호전된 뇌내출혈에 고혈압이 동반된 태음인 환자 치험 1례

오정민,엄태민,최고은,허종원,유호룡,설인찬,김윤식,Oh, Jeong-Min,Eom, Tae-Min,Choi, Ko-Eun,Heo, Jong-Won,Yoo, Ho-Ryong,Seol, In-Chan,Kim, Yoon-Sik 대한중풍순환신경학회 2014 대한중풍.순환신경학회지 Vol.15 No.1

■ Objectives The purpose of this case study is to report that a hypertension with intracerebral hemorrhage of tae-eumin was treated with 'Cheongsim Yeunja-tang' and then the symptoms were improved and blood pressure was decreased. ■ Methods Although the patient who had hypertension with intracerebral hemorrhage took antihypertension drugs, intermittent increase of blood pressure was shown. We diagnosed him as Tae-eumin and treated with Cheongsim Yeunja-tang. We daily checked blood pressure and evaluated the symptoms. ■ Results After the treatment with Cheongsim Yeunja-tang, blood pressure was decreased and symptoms were improved. ■ Conclusion The result shows Cheongsim Yeunja-tang has antihypertensive effect and improve hypertension symptoms of Tae-eumin patient with intracerebral hemorrhage.

MIKE21을 이용한 제주외항 해역에서의 폭풍해일고 산정

윤종태,방교진 경성대학교 공학기술연구소 2008 공학기술연구지 Vol.15 No.-

It is essntial to accurately estimate the transformations and behavior of waves for the design of safe and effective coastal structures Occurring frequency of strong typhoons is increasing because of global warming and it forces to consider the influence of storm surge before the construction of coastal structures Numerical experiment is performed to estimate the variation of storm surge in Jeju outport The applicability of MIKE21 HD module to the sea around Jeju is verified by comparing the simulated results with observed data and the variation of storm surge due to the quay construction of Jeiu outport is examined. Data of typhoons which passed or had signficant damages to the sea around JejU outport during last 30 years are collected and analyzed, and finally typhoon RUSA in 2002 and typhoon MAEMI in 2003 are selected as simulation typhoon. Simulated maximum surge heights are compared with observed data and they showed good agreements After the construction of quay wall, the surge heights at harbor inlet and interior area became smaller than before the construction, but the differences are so small to be neglected.

Rings운동에서의 Giant swing동작에 대한 운동학적 분석

윤희중,박종훈,한충식,김영란,김충태 韓國體育大學校附屬 體育科學硏究所 1992 韓國體育大學校附屬 體育科學硏究所論文集 Vol.11 No.1

This study was to investogate the kinematic patterns of the giant. swing on rings by 3 male gymnastic. The motion was filmed at 60frame/sec high video camera. The result was as follows ; 1. Subj. C showed a large displacement in the wrist J. at phase I and Subj. B showed a large displacement at phase 2, 3, 4. 2. Subj. C showed a large displacement in the hip J. at down swig phase and Subj.B, C showed a large displacement. at upward swing phase. 3. Subj. A showed a large velocity a in the hip J. at phase 1 and Subi. C shooed a large velocity at phase 2, 3, 4. 4. Subj. C showed a large velicity in the shoulder J. at whole phase. 5. Subj. C showed a large angular velocity in the hip J. at down swing phase and subj. B showed a large angular velocity at upward swing phase. 6. Subj. B showed a larege angular velocity in the shoulder J. at. phase 1, and Subj. C showed a large angular velocity at phase 2, 4 also subj. A showed a large angular velocity at phase 3.

2-Propanol-물 혼합용매에 대한 n-Alkylamine 염산염의 Partial Molal Volume에 관한 연구

윤상기,엄태섭,김봉규,박종열 東亞大學校 1977 東亞論叢 Vol.14 No.-

2-propanol-물 혼합용매계에 대한 n-alkylamine 염산염의 "겉보기몰랄부피" ø??를 부력법을 이용하여 30℃에서 측정하였다. Amine염 C??H??NH??Cl은 C??에서 C??에 이르는 저급 동족체를 시료로 하고 혼합용매 각 조성마다. 0.01M~0.2M 농도범위안의 용액에 대한 float의 무게를 소수점이하 5위까지 평량하였다. Limiting law equation에 의거 농도의 평방근 √vsø?? plot한 것을 C→0 즉 무한대의 묽은 쪽으로 extrapolation 함으로서 "분몰랄부피"V를 구하였다. 실험결과는 농도변화와 용매조성에 따른 ø?? 및 V의 변화, limiting slope S'와 ion의 charge effects 등에 대하여 논의하였다. 즉 √대 ø?? plot의 결과는 기울기가 크고 positive한 두 직선이 생기는데 이것이 √ 0.2부근에서 예리하게 교차되는 것이 관측 되었다. 또한 0.2m.f. 조성 때에 maximum의 S'와 minimum의 V?? 값이 나타나고 아울러 ion의 charge effect가 maximum임을 알았다. 실험결과는 또한 같은 시료를 methanol-물, ethanol-물 혼합계에 각각 적용한 결과와 비교하여 논의하였다. The apparent and partial moral volumes (ø?? and V??) of the lower homologous salts of n-alkylamine hydrochloride C??H??NH??Cl where C?? varies from C?? to C?? have been determined to the fifth decimal place at 30℃ by means of float method in 2-propanol-water mixtures, and the values of ø?? extrapolated to infinite dilution according to the limiting law equation give partial molar volumes. The experimental results are discussed in terms of the charge of ion and of the volume change in apparent molar volumes depend upon the increase of he concentration of the solutions and in partial molal volume according to the varing composition of mixed solvent. It has been observed that the plot of ø?? vs c?? showed sharp transition at approximately c?? 0.2 with anomalously positive and large slope, while the maximum charge effect related to the limiting slope S'?? causes minimum in V?? at 0.2 mole fraction of mixed solvent. It has been discussed and compared with respect to the results of the previous study as examined for the same sample species in methanol and ethnol-water mixtures respectively.

5-置換 헤테로고리 酸鹽化物 및 그 유도체에 대한 親核的 置換反應의 速度論的 硏究 : 5-브로모-2-염화휴로일의 가용매분해반응

尹床基,嚴泰燮,朴鍾烈 東亞大學校 大學院 1979 大學院論文集 Vol.3 No.-

Kinetics for the solvolytic reaction of 5-bromo-2-furoyl chloride have been studied in dipolar and aprotic solvent mixtures, i.e. acetonitrile-water and acetone-water while that of the reaction rates for the methanolysis are measured in non-aqueous binary solvents, i.e. acetonitrile and acetone with methanol cosolvent respectively by means of conductometery at various temperatures. Experimental results are interpreted in terms of solvent effect with varing the composition of binary mixtures and of the reactivities due to the substituent in the heteroaromatic ring in comparison with non-substituted 2-furoyl chloride. The reactivities and reaction mechanism are also reported by the analysis of activation parameters such as ΔS≠ and ΔH≠. The results are also showed that the rates of solvolysis are found to be faster in acetonitrile-water mixtures than those of it in acetone-water system. These behaviors are comparatively consistent with the order of solvent parameters Z and D values which denoting the polar character and dielectric constant of solvent respectively. The rates of methanolysis are increased with the increase of methanol content in non-aqueous binary mixtures, while those of it in acetonitrile-methanol mixtures are also faster than in acetone-methanol system. The order of reaction susceptibility attributable to the substituent in five-membered heteroaromatic ring is observed as 5-bromo-2-furoyl chloride > non-substituted 2-furoyl chloride because of electron withdrawing effect of the bromine atom in the hetero ring. The mechanistic results of solvolysis for the acid chloride is concluded as SN2 cathegory according to Grunwald-Winstein's and Kivinen's plots, and also as entropy controlled reaction on the basis of activation parameters.

Al₂O₃와 STS316의 브레이징 접합에 미치는 활성금속 Ti의 영향

윤종원,강준일 동의대학교 산업기술개발연구소 2006 産業技術硏究誌 Vol.20 No.-

Joinning of Al_(2)O_(3) to STS316 has been carried out using Ag-Cu braze fillers at the temperatures of 850, 950℃ under vacuum. Ag-Cu eutectic braze fillers did not react with Al_(2)O_(3) at 850℃ and no wetting or chemical bonding occurred. However, Ag-Cu active filler metal with the addition of Ti reacted chemically with Al_(2)O_(3) to cause wetting and chemical bonding. The Ag-Cu-Ti filler metal made reaction layers at both Al_(2)O_(3)/filler metal and filler metal/STS316 interface and caused diffusion of metallic elements such as Fe, Ni and Cr from STS316 into the braze alloys. Ti is continuously existed at both Al_(2)O_(3)/filler metal and filler metal/STS316 interface. Ti3Cu3O was observed at the filler metal/Al_(2)O_(3) interface made using Ag-Cu-Ti. Using the Ag-Cu active filler metal with the addition of Ti, brazing process had produced a sound interfacial bond.

통풍성 관절염의 임상적 고찰

윤채중,정승문,김영학,김동규,허광식,김태원,배학연,정종훈,이승일,김평남 朝鮮大學校 附設 醫學硏究所 1997 The Medical Journal of Chosun University Vol.22 No.2

통풍은 Purine 대사의 이상으로 발생하는 질환으로, 고뇨산혈증인 사람의 전부가 통풍으로 발현되지 않고 증상의 출현 양상이 다양하여 진단과 치료에 주의가 필요하며, 조기에 적절한 조치를 한다면 충분히 조절이 가능한 질환이다. 본대학 내과학교실에서는 통풍으로 치료한 32명의 환자에서 임상양상, 병력과 검사소견을 분석하여 다음과 같음 결과를 얻었다. 1. 32명 모두 남자이며, 최초 발병 시기는 24세에서 72세로 평균 43.8±11.9세이었으며, 30대에서 40대까지가 19명(59.4%)으로 대부분을 차지하였다. 내원 당시 나이는 27세에서 75세까지로 평균 52.3±10.4세였으며, 내원시 까지 평균 유병기간은 8.5±6.8년으로 나타났다. 2. 동반 질환으로는 고지혈증 12례, 신장질환 10례, 고혈압 12례, 비만 8례, 당뇨 2례 등이었다. 3. 이환된 관절은 단관절 침범이 19례(59.4%), 다관절 침범이 13례 이었으며, 최초 이한된 관절은 족무지 중족골지골 관절로 19례(59.4%)로 가장 많았고, 통풍 결절은 20례(62.5%)에서 관찰되었으며, 유병기간이 10년 이상된 12례중 11례 (91.7%)에서 결절이 관찰되었다. 4. 평균 혈중 요산치는 9.17±1.75 ㎎/dl이었으며, 8.0 ㎎/dl에서 9.9 ㎎/dl 사이가 19명으로 전체의 59.4%를 차지하였다. Objective: The gout is a heterogeneous group of diseases resulting from tissue deposition of monosodium urate or uric acid crystals from extracellular fluids supersaturated with respect to this end product of human purine metabolism. The clinical manifestations are such as hyperuricemia, gouty arthritis, gouty nephropathy, uric acid nephrolithiasis. We analyze of clinical manifestations and associated factors in gout. Method: We have reviewed the medical records, radiologic findings and clinical results of thirty-two patients admitted at our department from April 1996 to July 1997. Result: 1) All patients were male. The mean age at initial attack was 43.8 years old, ranging from 24 to 72 years old. 2) The mean level of serum uric acid was 9.17mg/dl on admission. 3) The first metatarsopharyngeal joint was involved in 19 cases (59.4%). Tophus was observed in 20 cases (62.5%). 4) Hyperuricemia was associated with hypertension, obesity, nephrolithiasis and hyperlipidemia.

해양매립에서 준설토 매립시 환경오염 영향 및 대책연구

엄태규, 윤종태 경성대학교 환경문제연구소 2000 環境硏報 Vol.10 No.1

The main findings through this study are summarized as conclusion below ; When dredge soil (ill to sea area, suspended soil widely spread from main area to north of ga-duk island without the pollutant's fence, Especially, the total area of ung-dong bay is more than 20㎎/ℓ as SS concentration and the pollution of north of gaduk Island is considerable. Therefore dredge was needed the pollutant's fence, Consequently the only that main area is more than 20㎎/ℓ as SS concentration, decreasing of pollution is explicitly acknowledged on the ocean because the others except for dredged area is less than 2∼8㎎/ℓ as SS concentration with the pollutant's fence. It is only considered SS concentration of dredge soil, because concentration of BOD, TN and TP were very lower than not concentration. Heavy metal concentration of the dredge soil is lower than not only the standard of heavy metal in the sea-water but heavy metal concentration including sediments with dredged area. It is decided that the polluted surrounding area has been little by heavy metal.