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여운철,조광현,이유신,허대석,이승철 ( Un Cheol Yeo,Kwang Hyun Cho,Yoo Shin Lee,Dae Seog Heo,Seung Chul Lee ) 대한피부과학회 1990 대한피부과학회지 Vol.28 No.5
A Case of Erythema Multiforme A ssociated with Malignant Lymphoma Un Cheol Yeo, M.D., Kwang Hyun Cho, M.D., Yoo Shin Lee, M.D., Dae Seog Heo*, M.D., Seoung Chul Lee**, M.D Department of Dermatology and Internal Medicine*, College of Medicine, Seoul National University, Seoul, Korea, Department of Dermatology**, College of Medicine, Inha University, Kyung Gi Do, Korea We report a case of erythema multiforme associated with malignant lymphoma. Fifty-six-year-old male patient visited our clinic complaining generalized skin lesions which were compatible with erythema multiforme clinically and histopathologically. The skin lesions were treatment-resistant, recurrent and persistent for 3 years. In consideration of old age, atypical features of erythema multiforme and no other demonstrable etiology of erythema multiforme, we studied for internal malignancy. Malignant lymphoma at the duodenum was revealed by UGI series, abdominal CT, and endoscopic biopsy. After chemotherapy, the tumor mass and active skin lesions were cleared simultaneously. Erythema multiforme may be regarded as one of the paraneoplastic syndromes.
효율적인 유비쿼터스 정보 공동활용을 위한 국가적 USN 정보자원 관리체계 구축 정책에 관한 연구
이재호,안철현,김유정,신상철,이재용 한국정보사회진흥원 2006 정보화정책 Vol.13 No.2
정보화 사회를 지나 유비쿼터스 사회로 발전하기 위한 핵심 기술 중 하나인 USN은 최근 기상, 군사 분야 등을 중심으로 현장∙실증 시험이 활발히 추진되고 있으며, u-City 같은 실제 사업에 적용하는 방안도 적극 검토되고 있다. 하지만, 현재까지 실증시험 결과 USN간 연계를 위한 식별체계, 프로파일, 통신프로토콜, 데이터 형식 등이 상이하여 향후 상호 연동을 위한 추가 비용이 크게 증가할 것으로 예상되고, 이는 기존 정보화 사회에서 행정 정보 공동활용과 유사한‘선구축-후통합’에 따른 문제점을 답습할 가능성이 높아 보인다. 따라서 본 논문에서는 USN 정보공동활용을 위한 USN 기술표준 및 정보 관리 체계를 수립하여 전국적 USN 정보자원을 효율적으로 관리하기 위한 정책 방안과 이를 실현하기 위한 USIS(Ubiquitous Sensor Information System)1)를 함께 제안하였다.
李汀帝,金鐘桓,金哲源,柳深根 한국전통의학연구소 2000 한국전통의학지 Vol.10 No.1
Dangguijagyagsan(DGJYS) is used in infertile. An attempt was to evaluate the influences of DGJYS on the serum concentrations of FSH, LH and estrogen, the histolgical and optical changes of ovary. The results of the study were as follows : 1. Blood FSH level increased in experimental group as compared with control group on 5th day and 10th day, which showed no efficacy. 2. Blood LH level decreased in experimental group as compared with control group on 5th day and 10th day, which showed no efficacy. 3. Blood E2 level increased in experimental group as compared with control group on 5th day and 10th day, which showed no efficacy. 4. In histolgical observations of ovary, ovulation increased in experimental group as compared control group on 5th day and 10th day, which showed no efficacy. 5. In optically observations of ovary, size of ovary showed no change in exerimental group as compared with control group on 5th day and 10th day. 6. In histological observations of ovary, endometrium showed multiplication. According to these results, the effects of DGJYS are assumed to be usefully utilized for progress of ovulation on uterus and ovary.
일측성선조체의 6-OHDA손상 후 도파민효능약물 투여로 발현된 회전운동의 특성
이순철,문민선,이수정,유민,윤철호,유관희 충남대학교 약학대학 의약품개발연구소 1997 藥學論文集 Vol.13 No.-
The present study examined the characteristics of behavior induced by dopamine agonists following treatment with 6-hydroxydopamine(6-OHDA) unilaterally into left striatum in rats. 6-OHDA was administered at doses of 8.16 and 24 ㎍/2㎕(in 0.1% ascorbic acid) into dopaminergic neurons in left striatum of 7 weeks old rat under anesthetic. Locomotor activity was significantly decreased at 1 week following 6-OHDA-administration in 7 weeks old rats. The contralateral circling behaviour was inducd by apomorphine(5 ㎎/㎏, I.p.) after 1 week following 6-OHDA(24 ㎍/2㎕) treatment, and was further increased by repeated administration of apomorphine at 2, 3 and 4 weeks. The contralateral circling behavior was also induced by lisuride and 1-dopa in a dose dependent manner, but not by SK & F 82526 in 7 weeks old rats treated with 6-OHDA, The contralteral circling behavior ws significantly higher in 21 weeks old rats but significantly lower in 35 weeks old rats when compared with 7 weeks old rats. The contralateral circling behavior induced by apomorphine did not differ significantly in and 35 weeks old male and female rats. These results suggest that 6-OHDA treatment into left striatum causes remarkable destruction of intrastriatal dopaminergic neurons leading to dopaminergic receptor supersensitivity. Thus, the contralateral circling behavior induced by apomorphine may be used as indicator for neurodegenerative diseases.
걷기운동 시간이 혈청지단백 및 아포지단백에 미치는 영향
이기철,권유찬,박진기 부산 외국어 대학교 2002 外大論叢 Vol.25 No.-
The purpose of this study was to investigate the changes of serum lipoprotein and apolipoprotein after 80min aerobic exercise. Subjects were composed of seven obese women. lipoprotein was determined for each subjects by administering a treadmill exercise test. The exercise intensities was 80%HRmax. The result of this study are as follows ; 1. Free fat acid was increased during walking exercise each 20min, 40min, 80min. 2. HDL-C was increased and LDL-C was decreased during walking exercise. Especially, more change at 80min. 3. Apo A-Ⅰ and Apo A-Ⅱ was significantly(p<.01) increased during walking exercise. 4. Apo C-Ⅱ was not changed, but Apo C-Ⅲ was decreased during walking exercise at 40min, 80min, In conclusion, bout walking exercise was shown to positive influence on serum lipoprotein and apolipoprotein. So it is maybe thought that walking exercise improved lipoprotein metabolism for obesity treatment.
주유철,이동민,양종태,신병철,임태영,서정균,정기영,최동헌,김원,조영신,고희관 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2
Background and Objectives : Palindromic rheumatism (PR) is known to be triggered without any obviously inciting events in most patients, although, in a few cases, attacks have been noted to relate to another events such as weather change, childbirth, ingestion of certain foods, or over-exercise. The aim of this study was to characterize the triggering factors on palindromic attacks. Materials and Methods : We evaluated sixty-four patients with PR for the presence of triggering factors and the relationship between attacks and triggering factors by interview of patients. We considered that there was an probable association between episodes and PR, if episodes within 24 hours prior to PR had triggered at least 50% of all attacks and a definite association between episodes and PR, if episodes within 24 hours prior to PR had triggered 100% of all attacks. Results : In 15 patients (35.9%), there was a possible association between episodes of PR and initiating events. In 8 patients (12.5%), there was a definite association between episodes of PR and initiating events. The triggering factors were physical over-activity including exercise (19/64: 29.7%), foods, such as rawfish, crab, and chicken, including alcohol (19/96: 19.8%). However, there were no difference between the groups with and without the triggering factor in sex ratio, duration and onset of PR, the positive rate of rheumatoid factor and involved sites. Conclusion : Our observations showed that PR was triggered by physical over-activity more than in previous reports and hypersensitivity to foods was a causative factor in some patients with PR. However, patients with triggering factors had a similiar clinical profile to patients without triggering factors.