RAPD 분석에 의한 굴참나무 집단의 유전변이 연구

송정호,김남수,이용섭,김영중,송재모,이재선 한국유전학회 2002 Genes & Genomics Vol.24 No.2

Quercus variabilis is one of the most important tree species in both utilization of forest resources and management of forest ecosystem in Korea. To obtain the basic information for the establishment of breeding strategy and efficient management of genetic resources, five populations of Q. variabilis from 89 selected plus trees were studied using POPGENE and AMOVA analysis based on DNA markers focussing on the genetic diversity and variation among populations. The overall polymorphic amplicons were 78.6% and levels of genetic diversity within 5 populations were similar each other (Shannon's Index : 0.289∼0.423 [mean 0.366]). The values of total genetic diversity (H_t) and average gene diversity within population (H_S) were 0.265 and 0.239, respectively. The degree of genetic differentiation (G_st : 0.098) was relatively high compared with those of other tree species. Based on the cluster analysis of UPGMA, genetic relationships among 5 populations were not coincided with the pattern of geographic distribution.

사과 腐爛病 防除를 위한 基礎調査

함승희,서영주,정은미,채선희 효성여자대학교 문리과대학 학도호국단 1984 文理大論集 Vol.4 No.-

This study was carried out to get the basic date for effective control of apple canker disease in Daegu; Chilgog, Gyeongsan, and Weolseong, which were major appleproduction districts. The relationship among occurence rate of apple canker, district, infected side of trunk, and nutrition state of apple leaf were examined. The results of the study were summarized as follows. 1. The occurence rates of apple canker were a little high in Yeongcheon and Gyeongsan district as 81.7%, 83.5% respectively, but in Chilgog district was 70.2%. 2. The occurence rates were high in Spur Early Blaze, Spur Golden and Megumi varieties as 84.8%, 87.3%, 88.6% respectively, but in Rallss Genet, Moris delicious, Starkrimson, Raritan variety were tend to lower as 69.4%-72.3%. 3. The occurence rate of free stocked tree was high as 81.8%, But in dwarf stocked tree was low as 73.8%. 4. The occurence rate was 80.7% in trunk and main blanch part, and in the east and south side of trunk. The occurence rate of apple canker was 55.7%. 5. There was significant positive correlation(r=0.516^*)between occurence rate of apple canker and N content of apple leaf, but negative correlation (r=-0.589^*) in P_2O_5 content. 6. Occurence rate of apple canker was tend to higher as the ca/Mn ratio in apple leaf was lower.

신체형 환자의 애착 특성

김용희,송지영,반건호,김종우,신용선 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The purpose of this study was to evaluate the relationship betseen attachment style and somatization in patients with somatoform disorder. Methods : Data was collected by self-report questionnaires. 134 normal subjects and 30 patients with somatoform disorder were enrolled in this study. All subjects completed a psychometric assessment that consisted the Revised Adults Attachment Scale(RAAS), Inventory of Parent and Peer Attachment (IPPA), Sungshin Self-concept Inventory (SSCI), and SCL-90-R. Results : 1) Somatoform patients showed more anxious attachment style than normal control. 2) Anxious attachments were combined with mistrust of their parents, emotional instability, and interpersonal mistrust which may play a significant portion of variance in somatization. Conclusion : We found that patients with somatoform disorder had more anxious attachment style than normal subjects. Insecure attachment patterns may significantly explain the phenomenon of somatization.

장거리 달리기 선수에서 횡문근융해와 생화학적 지표의 변화에 대한 연구

안선호,최석채,김태현,나용호,송주흥,이영진,조지현,최석준 대한신장학회 2000 대한신장학회잡지 Vol.19 No.5

두경부 마사지가 중환자실 환자의 수면과 불안에 미치는 효과

김미용,전선영,송윤희,최은진,김재희,김미성,주명순,김남선 병원간호사회 2006 임상간호연구 Vol.11 No.2

Purpose: This study was to apply head and neck massage to patients in intensive care unit and to inventigate the effect of that massage on sleep and state anxiety. Method: The subjects in this study were 27 patients who were admitted in medical intensive care unit. The study was performed from June thru September of 2005 on the One-group pretest-posttest design and the sleep, state anxiety of the subjects were measured before and after head and neck massage. For data analysis, paired t-test and Pearson correlation coefficient were utilized. Result: The first hypothesis that the subjects might have a better sleep after being exposed to head and neck massage was accepted. The second hypothesis that the subjects might feel less state anxiety afrer being exposed to head and neck massage was accepted. The third hypothesis that the sleep of the ICU patients maight be correlated to their anxiety was accepted, as there appeared correlation between their sleep and anxiety. Conclusion: Head and neck massage is identified as one of independent nursing interwentions to improve the sleep of ICU patients and ease their anxiety, and it is necessary to apply it to clinical practices.

모세관 전기영동법을 이용한 6-Acetonyl-dihydrosanguinarine 광학이성질체의 분리

임환미,송용선,김영호,강종성 충남대학교 약학대학 의약품개발연구소 2002 藥學論文集 Vol.17 No.-

Hylomecon hylomeconoides is the endemic plant growing in southern part of Korea and belongs to Papaveraceae family and contains many benzophenanthridine alkaloids. As a benzophenanthridine alkaloid 6-acetonyldihydrosanguinarine (ADS) was extracted from Hylomecon hylomeconoides and the separation of enantiomers was performed by capillary electrophoresis (CE). The effects of type of chiral selectors, pH and concentration of electrolyte on the resolution of ADS enantiomers were observed for the optimization of separation method. The optimum separation of the ADS enantiomers was achieved on fused silica capillary (75 um i.d.×47 cm, 40 cm to detector) with phosphate buffer (pH 7, 50 mM) added 4.55 mM of 2-hydroxypropyltrimethylammoniumpropyl-β-cyclodextrin (TMA-β-CD) as electrolyte at 10 kV running voltage. Injection was hydrodynamically for 3 psi×s and detection was carried out at UV 205nm.

유기질비료 시비량에 따른 오미자 묘목의 초기 생육특성에 관한 연구

이경아,박태호,박성용,김도현,오문국,김민수,안태진,이상원,김영국,안영섭,박충범,차선우,송범헌 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.1

This study was carried out to have basic and applied informations to find the optimum nitrogen fertilization level for organic cultivation and to investigate early growth characteristics of Schizandra chinensis Baillon. Different application levels of the organic fertilizer were based on the recommended rate of N fertilizer. Five different levels of the organic fertilizer were applied to S. chinensis and early growth responses such as the length of vine, the diameter of vine, the number of leaves, and the number of branches were investigated. Lengths of main and total vines were shown longer at the level of 1.0 time organic fertilizer than those at others. The vine length at early growth was the highest at the level of 1.0 time organic fertilizer among the treatments. Stem diameter was shown thicker level of 1.0 time organic fertilizer than others on August and September, whereas on October it was the thickest in the conventional cultivation. Number of leaf was increased higher at the level of 1.0 and 2.0 times organic fertilizer than that in the compared to conventional. The number of branches was appeared the lowest at the level of 1.0 time organic fertilizer at early growth, however they were increased through progressing their growth stages. They were not significantly difference among the treatments except for the level of 2.0 times organic fertilizer. Based on the research results, the growth of S. chinensis was commonly higher at the level of 1.0 time organic fertilizer compared to other treatments.

사람폐암세포주 (PC-14)에서 Cyclosporin A에 의한 Adriamycin 내성의 극복

김영환,홍원선,송재관,강윤구,이진오,강태웅,김건열,한용철 대한내과학회 1990 대한내과학회지 Vol.38 No.3

Cyclosporin A and verapamil were tested using MTT assay to evalute the modification effect on the resistance to adriamycin in a human lung cancer cell line(PC-14) and its resistant subline(PC-14/A). PC-14/A was derived by the continuous exposure of PC-14 to incremental concentrations of adriamycin. PC-14/A was 2.5 times more resistant to adriamycin in terms of ICso than PC-14. Cyclosporin A alone, at a concentration of 2.5㎍/㎖, inhibited the growth of PC-14 to 68.3%. 2.5㎍/ ㎖ and 5.0㎍/㎖ of cyclosporin A showed an increase in the cytotoxicity of adriamycin (p<0.01) with 5.0㎍/㎖ being greater than 2.5㎍/㎖(p<0.01). Excluding the direct cytotoxic effect, however, cyclosporin A did not increase in the sensitivity of PC-14 to adriamycin but only showed an additional cytotoxic effect with adriamycin. Verapamil (up to 6.0㎍/㎖) did not inhibit the growth of PC-14. 3.0㎍/㎖ of verapamil did not increase the cytotoxic effect of adriamycin. The combination of cyclosporin A and verapamil with adriamycin enhanced the cytotoxicity of adriamycin, but the result was similar to that of cyclosporin A with adriamycin. 5.0㎍/㎖ of cyclosporin A modified the adriamycin resistance of PC-14/A(SR, 3.2). However, 3.0㎍/㎖ of verapamil did not significantly reverse the adriamycin resistance of PC-14/A. The modified effect of the combination of 5.0㎍/㎖ of cyclosporin A and 3.0㎍/㎖ of verapamil was similar to that of 5.0㎍/㎖ of cyclosporin A alone in PC-14/A. These results demonstrate that cyclosporin A has an additional cytotoxic effect with adriamycin in PC-14 and PC-14/A and has overcome the acquired resistance to adriamycin in PC-14/A. They also suggest that cyclospoin A may have the therapeutic potential in the treatment of human lung cancer.

정신분열병 환자를 위한 인지재활훈련 프로그램의 개발 : Korean-Cognitive Differentiation Program 한국형 인지분화훈련 프로그램

현명호,안석균,이만홍,조현상,최충식,이연희,송선미,유계준,김장우,김태용,이희상 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.2

연구배경 : 정신분열병 환자들은 인지장애를 보이는바, 저자들은 이들을 대상으로 한국형 인지분화훈련 프로그램을 개발하여 정신분열병 환자들을 대상으로 인지재활훈련을 실시한 후 환자들의 인지기능, 정신병리 및 문제해결기술에 미치는 효과를 조사하였다. 방 법 : 28명의 정신분열병 환자를 훈련군(n=14)과 대조군(n=14)으로 나누어 훈련군에게 한국형 인지분화훈련 프로그램을 1회 60분씩, 주당 2회씩, 11주간 총 22회를 실시하였다. 환자들의 인지기능은 K-WAIS의 산수, 빠진곳찾기, 어휘, 공통점찾기 소검사로 측정하였고 정신병리는 양성 및 음성증상 척도로 측정하였으며 문제해결기술은 사회문제해결척도로 평가하였다. 인지재활훈련의 효과를 평가하기 위해 훈련 전후의 인지기능, 정신병리 및 문제해결기술의 변화를 종속변수로 하고 훈련 유무를 독립변수로 하여 반복측정에 의한 변량분석으로 자료를 분석하였다. 결 과 : 한국형 인지분화훈련이 시간에 따른 인지기능검사 중 산수 소검사, 문제해결기술 중 시회문제해결척도의 전체 점수와 문제해결기술 소척도의 점수의 변화에 유의한 영향을 미쳤으나, 시각적 주의력, 개념화 능력 및 정신병리의 점수의 변화에 유의한 영향을 미치지 않았다. 결 론 : 한국형 인지분화훈련 프로그램은 정신분열병 환자에서 청각적 주의력 및 문제해결기술의 호전을 꾀할 가능성이 있음을 시사한다. Objectives : The purpose of this study was to investigate the effects of cognitive differentiation training program- Korean version(a training program of attention and conceptual abilities) on cognitive function, psychopathology and problem solving skills in patients with schizophrenia. Methods : A total of patients diagnosed as schizophrenia using DSM-Ⅳ were randomly assigned to 2 groups. The training group went through a total of 22 sessions of cognitive differentiation training(60 min/ session×2 sessions/wk×11 wks). The attention-placebo control group received psychoeducation program during the same period. Arithmetic, vocabulary, similarities, picture completion of Wechsler Adult Intelligence Scale-Korean version, Positive and Negative Syndrome Scale, and Social Problem Solving Scales were administered to all patients, both before and after the training program. Results : In the arithmetic scores(F=6.35, af=1, p=0.018) of Wechsler Adult Intelligence Scale-Korean version, and total scores(F=6.35, af=1, p=0.018) and problem solving skill scale scores(F=4.88, af=1, p=0.036) of social problem solving scale, interaction effects of training was significant. Conclusion : Our findings suggest that cognitive differentiation training program-Korean version is effective on improving auditory attention and problem solving skills in patients with schizophrenia.

Broadband Alcock-Paczynski test exploiting redshift distortions

Song, Yong-Seon,Okumura, Teppei,Taruya, Atsushi American Physical Society 2014 PHYSICAL REVIEW D - Vol.89 No.10

The baryon acoustic oscillation (BAO), known as one of the largest cosmological objects, is now recognized as a standard cosmological tool to measure geometric distances via the Alcock-Paczynski effect, by which the observed BAO exhibits characteristic anisotropies in addition to the redshift distortions. This implies that once we know the correct distances to the observed BAO, the tip points of baryon acoustic peaks in the anisotropic correlation function of galaxies, xi(sigma,pi), can form a great circle (hereafter the two-dimensional BAO circle) in the sigma and pi plane, where sigma and pi are the separation of the galaxy pair parallel and perpendicular to the line of sight, respectively. This two-dimensional BAO circle remains unchanged under the variations of the unknown galaxy bias and/or coherent motion, while it varies transversely and radially with respect to the variations of D-A and H-1, respectively. Hereby the ratio between the transverse distance D-A and the radial distance H-1 reproduces the intrinsic shape of the two-dimensional BAO circle, which is a priori given by the known broadband shape of spectra. All BAO peaks of xi(sigma,pi) are precisely calculated with the improved theoretical model of redshift distortion. We test this broadband Alcock-Paczynski method using baryon oscillation spectroscopic survey-like mock catalogues. The transverse and radial distances are probed in precision of several percentage fractional errors, and the coherent motion is observed to match with the fiducial values accurately.