갑상선 기능항진증 환자에서 인슐린감수성 및 인슐린분비능의 변화

최은진,강호철,이태희,정민영,이대호,장연진,박상선,조재현 대한내분비학회 1994 Endocrinology and metabolism Vol.9 No.2

The impairement of glucose metabolism is frequently associated in hyperthyroidism. The present study was performed to determine the effect of the thyroid hormone excess on insulin sensitivity and on insulin secretory function in vivo. Ten newly diagnosed hyperthyroid patients and fifteen healthy control subjects were subjected to frequently sampled intravenous glucose tolerance tests(FSIGT) after an overnight fast. Insulin sensitivity, represented by the insulin sensitivity index(S_1), was assessed by minimal model analysis of FSIGT data. Insulin secretion was measured by the total area under the insulin curve after glucose load. The results were as follows. 1) The K_G values, which represent glucose tolerance, were not different between the hyperthyroid patients and the normals(2.2+-0.3 vs. 2.5+-0.3%/min, p$gt;0.05). 2) S_1 was significantly decreased in the hyperthyroid patients in comparison to the normals(7.5+-1.4 vs. 2.6+-0.3X10^-4 min^-1/uU/ml, p$lt;0.05). 3) The basal insulin concentration was higher in the hyperthyroid patients than in the normals(8.3+-2.4 vs. 4.6+-0.4 uU/ml, p=0.07). In addition, the insulin secretory response to a glucose load was increased in the hyperthyroid patients as evidenced by the peak plasma insulin level(168.2+-30.4 vs. 89.2+-13.9 uU/ml, p$lt;0.05) and by the total area under the insulin curve(2641.1+-443.2 vs. 1696.7+-204.3 min uU/ml, p$lt;0.05). These results clearly demonstrated that insulin sensitivity was impaired in these newly diagnosed hyperthyroid patients. However, glucose tolerance was maintained by the increased insulin secretion (J Kor Soc Endocrinol 9:108-114, 1994).

조리원 작업 시간 분석에 따른 생산성 연구

최은진,김선효,장세리,김현정,Choe, Eun-Jin,Kim, Seon-Hyo,Jang, Se-Ri,Kim, Hyeon-Jeong 대한병원협회 1993 대한병원협회지 Vol.22 No.4

이 논문은 동아대학교병원 개원 3주년 기념 학술대회 수상작이다. <편집자>

Effect of Selenium on Oocyte Maturation and Viability in vitro in Mouse

최은진,홍순갑,김해권,윤용달,이준영 한국발생생물학회 2006 발생과 생식 Vol.10 No.2

본 실험은 생쥐 난자의 성숙과 생존에 미치는 selenium의 영향을 알아보고자 수행하였다. 난자의 성숙은 현미경을 통해 관찰하였으며, 핵막 붕괴(germinal vesicle breakdown, GVBD)와 극체 형성(polar body formation, PB)은 체외 배양 시작 후 각각 2.5, 13시간에 확인하였다. 난자의 생존은 72 시간동안 체외 배양하면서 형태학적 차이로 정상 난자와 비정상 난자를 판별하였다. 또한 각 단계별로 수집된 난자의 The present experiment was performed to confirm the effects of selenium on maturation and viability of mouse oocyte. Maturation of oocytes was observed by microscope, Germinal vesicle breakdown(GVBD) and polar body formation(PB) were confirmed at 2.5, 13 hours after in vitro culture. Viability of oocytes was observed by microscope. Normal and abnormal oocytes were distinguished by morphological change in vitro culture for 72 hours. Glutathione(GSH) content of collected oocytes from individual stage also was measured by glutathione assay using spectrophotometer. The results obtained were as follows; The low concentration of selenium() increased the maturation rate of germinal vesicle(GV) oocytes to GVBD and PB oocytes. The high concentration of selenium() decreased the maturation rate. The low concentration of selenium increased the viability rate of PB oocytes. The high concentration of selenium did not affect the viability rate. The low concentration of selenium increased the GSH content in PB oocytes. The high concentration of selenium decreased GSH content. GSH content in PB oocyte was much higher than that in GVBD oocyte. The results indicate that the low concentration of selenium increases the maturation rate by helping quality elevation of oocyte and minimizing damages of oxidative stress generated from metabolism process. The low concentration of selenium also increases the viability rate by increasing GSH content.

지리적 기원이 다른 Pseudomonas syringae pv. actinidiae 균주들의 표현형적 특성

최은진,이영선,김경희,고영진,정재성,Choi, Eun Jin,Lee, Young Sun,Kim, Gyoung Hee,Koh, Young Jin,Jung, Jae Sung 한국미생물학회 2014 미생물학회지 Vol.50 No.3

Pseudomonas syringae pv. actinidiae is the causal agent of bacterial canker in kiwifruit (genus Actinidia). Multilocus sequence analysis of seven housekeeping and 11 type III effector genes differentiated the virulent P. syringae pv. actinidiae isolates worldwide into three groups designated as Psa1-Psa3. In this work, a total of 12 P. syringae pv. Actinidiae strains, including three Psa1, three Psa2, three Psa3 strains isolated from Korea and three Psa3 strains from Italy, were compared based on their phenotypic properties. Strains with different geographic origins had unique growth patterns as demonstrated by growth rate at several temperatures; all tested strains exhibited maximum growth at temperatures below $22^{\circ}C$, while the growth of Psa3 strains was completely inhibited above $30^{\circ}C$. Psa3 strains isolated from Korea had longer lag phases than the Psa3 strains from Italy. The Psa2 strains were different from Psa1 and Psa3 strains in the API 20NE test, in which the Psa2 strains could not utilize potassium gluconate, capric acid and trisodium citrate. Psa3 strains isolated from Korea could hydrolyze esculin. The API ZYM test showed that ${\beta}$-glucosidase activity was detected only from Psa3 strains. The strains belonging to the three Psa groups differed with regard to their susceptibility to ampicillin, novobiocin, and oleandomycin.

중국의 황옌페이(黄炎培) 연구동향의 지적 구조와 네트워크

최은진 한국중국학회 2026 중국학보 Vol.117 No.-

본 연구는 중국 CNKI에 2026년 5월까지 발표된 황옌페이(黄炎培) 관련 논문 중 저자와 키워드가 명확한 970편을 대상으로 키워드 동시출현 분석, 저자 네트워크 분석, PNNC 군집분석을 실시하여 중국 황옌페이 연구의 지적 구조와 연구동향을 규명하였다. 기존 연구가 주요 연구성과를 시기별·주제별로 정리하는 서술적 접근에 머물렀다면, 본 연구는 계량적 네트워크 분석을 통해 연구주제 간의 관계와 연구자 집단의 구조를 함께 밝혔다는 점에서 의의가 있다. 분석 결과, 첫째, 황옌페이 연구는 직업교육을 중심으로 매우 높은 집중성을 보이는 구조를 형성하고 있었으며, '직업교육'과 '황옌페이 직업교육사상'이 전체 연구를 연결하는 핵심 축으로 기능하였다. 둘째, 연구주제는 직업교육의 철학과 교육이념, 현대 직업교육정책, 산업·교육 융합과 학교-기업 협력, 직업도덕 및 교육방법론이라는 네 개의 핵심 축으로 구조화되어 있었으며, 최근에는 신질생산력 등 국가정책과 직결되는 새로운 주제가 지속적으로 등장하고 있었다. 셋째, 저자 네트워크 분석에서는 특정 연구자를 중심으로 한 강한 연구공동체나 학파는 확인되지 않았으며, 비교적 분산된 연구구조가 나타났다. 이러한 결과는 중국의 황옌페이 연구가 단순한 교육사 연구를 넘어, 국가 직업교육정책의 변화와 긴밀히 연동되는 정책지향적 연구영역으로 발전하고 있음을 보여준다. 황옌페이는 역사적 교육가를 넘어 현대 중국 직업교육정책의 정당성과 방향성을 설명하는 상징적 지식자원으로 기능하고 있는 것이다. This study examines the intellectual structure and research trends of Huang Yanpei (黄炎培) studies in China by conducting keyword co-occurrence analysis, author network analysis, and PNNC clustering analysis on 970 papers with clearly identified authors and keywords, published on CNKI through May 2026. While prior research has largely remained descriptive, organizing major findings by period or theme, this study contributes by using quantitative network analysis to reveal both the relationships among research topics and the structure of research communities. The findings are as follows. First, research on Huang Yanpei shows a highly concentrated structure centered on vocational education, with "vocational education" and "Huang Yanpei's vocational education thought" functioning as the central axes connecting the entire body of research. Second, the research topics are structured around four core themes: the philosophy and ideology of vocational education, contemporary vocational education policy, industry-education integration and school-enterprise cooperation, and vocational ethics and pedagogical methodology. New topics closely tied to national policy—such as new quality productive forces (新质生产力)—have continued to emerge in recent years. Third, the author network analysis found no strong research community or school centered on a particular scholar; instead, the research structure was relatively dispersed. These results indicate that Huang Yanpei studies in China have developed beyond simple historical inquiry into a policy-oriented research field closely linked to shifts in national vocational education policy. Huang Yanpei functions not merely as a historical educator but as a symbolic intellectual resource that legitimizes and directs contemporary Chinese vocational education policy.

A Postoperative Thrombotic Thrombocytopenic Purpura in a Cardiac Surgery Patient: A Case Report

최은진,이섭 대한흉부외과학회 2013 Journal of Chest Surgery Vol.46 No.3

Although thrombotic thrombocytopenic purpura (TTP) is a rare disease, when it develops in a post-cardiac surgery patient, it may have a fatal outcome. Since the frequency of early-onset thrombocytopenia in post-cardiac surgery patients is high, platelet concentrates are commonly transfused during postoperative management. However, when TTP is the likely diagnosis, platelet transfusion is not recommended. We experienced a postoperative TTP in a cardiac surgery patient and discovered the importance of identifying the etiology of postoperative thrombocytopenia. Here, we report the case with a brief review of the literature.

Two cases of postoperative chylothorax treated with parenteral octreotide and conservative therapy

최은진,이섭,Choi, Eun Jin,Lee, Sub The Korean Pediatric Society 2007 Clinical and Experimental Pediatrics (CEP) Vol.50 No.3

Chylothorax is a rare complication following cardiac surgery for congenital heart diseases. Although conservative management is successful in the majority of cases, surgical intervention is required in a refractory one. Recently, subcutaneous or intravenous infusion of octreotide has been used as a safe treatment that helps avoiding surgical intervention. Herein, we report two cases of postoperative chylothorax treated with parenteral octreotide and conservative therapy.

연수기 - 일본 성마리아 병원 연수기(1차)

최은진,Choi, Eun-Jin 한국가톨릭의료협회 2003 한국가톨릭병원협회지 Vol.33 No.-

자율협력주행을 위한 실시간 교통신호정보 제공과 활용

최은진,한향미 한국도로학회 2024 한국도로학회 학술대회 발표논문 초록집 Vol.2024 No.10

본 연구는 차내 정보 제공시스템을 통해 운전자에게 신호의 상태변화를 실시간으로 제공하는 것이 운전자의 운전행동에 어떤 영향 을 미칠지를 분석하고자 하였다. 신호정보제공에 따른 운전자의 반응은 신호등화의 변경시점과 브레이크 제동, 차량의 출발에 소요되 는 반응시간과 교차로 구간별 속도의 변화를 분석하였다. 또한 주행시험 전후 피시험자를 대상으로 서비스에 대한 사전 사후 설문을 실시함으로서 운전자의 성향과 서비스에 대한 만족도를 조사하고자 하였다. 실시간 교통신호상태정보 제공에 따른 설문조사는 일반설문과 사전설문, 사후설문으로 구성하여 피시험자 60명을 대상으로 수행하였 다. 장치조작에 익숙한 20-30대는 신호정보제공에 대한 기대 및 선호도가 낮게 나타났으며 60대 이상에게 운전편의성 및 선호도에 대 해 높은 만족도를 보였다. 연령대가 낮은 운전자에게서는 단순 정보제공의 의미, 고령운전자에게서 차량속도 조절 등 운전편의 효과를 확인 할 수 있었다. 주행시험은 동일한 경로를 주행하되 잔여시간정보를 제공하지 않는 일반주행과 정보를 제공하는 2번의 주행시험을 실시하였고, 반응 시간과 주행속도를 분석하였다. 잔여시간 정보를 제공하는 경우 브레이크 제동상태에 대한 반응시간은 전 연령대에서 통계적으로 유 의미한 반응시간 감소 효과가 있음을 확인하였다. 브레이크 반응시간은 평균 0.38초 감소하였고 특히 고령운전자 그룹에서의 반응시간이 66%가량 감소했다. 반면 2030대 운전자 그룹에 서는 등화가 변경되기 전에 예측반응하는 비율이 크게 증가하는 효과도 있었다. 그러나 예측반응은 제동상태의 변화가 있었던 것을 의미하므로 차량이 실제 움직인 예측출발과는 차이가 있다. 동일 데이터 분석 시 실제 2030대운전자 그룹에서 등화가 변경되기 전에 예측 출발한 빈도는 정보를 제공하기 전과 후 모두 7%로 변화가 없었기 때문이다. 출발인지반응은 전체반응시간의 감소가 통계적으로 유의하지 않았으나, 고령운전자 그룹에서 반응시간이 2.1초에서 1.8초로 -0.3초 통 계적으로 유의미한 감소가 있었던 것으로 분석되었다. 신호정보제공에 따른 주행속도의 변화는 적색등화 상태로 교차로 접근시의 평 균속도가 약 2km/h 감소하였으나, 녹색등화시에는 구간의 평균주행속도에는 큰 영향을 미치지 않는 것으로 분석되었다. 다만, 일반주 행 시 차량의 속도는 정지선으로부터 차량의 위치에 영향을 많이 받지만 잔여시간정보를 제공할 때는 거리보다 잔여시간의 영향이 더 크다는 사실을 확인하였다.

15-16세기 케임브리지 퀸즈 칼리지의 성장과 영속적 챈트리

최은진 한국서양중세사학회 2010 서양중세사연구 Vol.0 No.25

In medieval European universities, colleges were established as charitable institutions helping poor scholars to carry on studying higher faculty. In the early 14th century and late 15th century, the University of Cambridge achieved a remarkable degree of progress in promoting secular college movement. In the late 15th century, newly founded colleges in Cambridge were growing rapidly while existing ones were also expanding significantly. Colleges during this period began to attract new benefactors by promoting the religious function of the institution as perpetual chantries, which consequently enabled them to a rapid growth during 15th century. All college chapels initially functioned as chantries for founders and their families. To secure steady source of income and to maintain a bigger number of fellows, many colleges began to find new benefactors by offering them funeral services and intercession mass. Queens’ College, Cambridge serves as a vivid example of a college whose members’ engagement in attracting patronages had been particularly active. Although its official foundress was Margaret of Anjou and it had many royal patrons, most support from them had been little more than symbolic gestures. It was therefore necessary for Queens' College to strengthen the chantry function of the college to attract alternative financial resource in order to acquire land, construct college buildings, and provide living expenses for the fellows. After Henry Ⅷ’s Reformation, however, many colleges were no longer possible to function as perpetual chantries. This is because the focus of college activities was shifted to providing educational functions, including lectures and tutorials. Colleges began to accept commoners to make the college economically sustainable, and this move gradually led them to grow as a secular educational institution.