이질균의 R Plasmid의 유전적 특성

서민호,서성일,박종욱 啓明大學校 醫科大學 1988 계명의대학술지 Vol.7 No.2

In order to choose adequate antimicrobial drugs for shigellosis and to know the mechanisms of durg resistances and molecular epidemiologic data, 67 strains of Shigella flexneri and 11 strains of Shigella sonnei were tested for the antimicrobial susceptibilities, conjugal transfer of R plasmids, incompatibility grouping, plasmid DNA profiles and the recombinations of resistance genes. In S. flexneri, 88.1 to 97% of the strains were susceptible to kanamycin(Km) and rifampicin(Rf), 76.1% of the strains were susceptible to nalidixic acid(Na) and 37.3 to 52.2% of strains to sulfisomidine(Su), trimethoprim(Tp), and cotrimoxazol(Co). In S. sonnei, 100% were susceptible to Km and Rf, and 63.6% to Na. There was no susceptible strain to Cm, Tc, Sm, and Su. In contrast to S. flexneri, many strains(81.8%) of S. sonnei were susceptible to Ap and few(0 to 9.1%) strains to Su, Tp, and Co. Most of drug resistances except to Na and Km in 50 to 100% of resistant strains were co-transferred to recipient E. coli RG488, indicationg that multiple drug resistances were R plamid mediated phenomenon. Most of R plasmids were 62.4 mega dalton(Mdal) in size and classified into the incompatibility group FⅡ. Somewhat larger plasmids, 115.6Mdal in size were frequently found in Shigella. Doubles containing both resistances of incoming plasmid and resident plasmid in incompatibility grouping were tested for the plasmid DNA profiles and the conjugations to the plasmid free recipient. According to these results, we fround that doubles had single recombinant plasmid, 64.5 Mdal in size and the mechanisms of the recombination of these resistance genes were thought to be transpositions between two plasmids.

Retinoblastoma Tumor Suppressor Protein

서민호 동국대학교 의학연구소 1999 東國醫學 Vol.6 No.-

석·골재용 암석의 풍화에 따른 특성 변화

민경원,서백수,진호일,임길재 강원대학교 부설 석재복합신소재 제품연구센터 2000 석재연 논문집 Vol.5 No.-

화강암의 조직을 고려하여 4개지역에서 6개 석ㆍ골재 석산을 대상으로 신선한 화강암과 풍화된 화강암을 Ⅰ ~ Ⅵ단계까지 체계적으로 채취된 화강암을 대상으로 풍화에 따른 화강암의 물리적ㆍ화학적 특성 변화에 대한 고찰(민경원 등, 1998)에 추가하여, 풍화에 의한 slake 내구성과 색도의 변화를 측정하고 토의하였다. slake 내구성 시험에서는 일반적으로 Ⅰ~Ⅲ 단계의 화강암이 시험 주기가 증가할수록 선형적이 질량감소를 보이고 Ⅳ~Ⅵ 단계에서는 곡선 모양의 감소 경향을 보여주면 세립질의 화강암이 상대적으로 높은 내구성을 가진다. 풍화에 따라 암석의 백색도는 감소하고 황색도는 증가하며, 표준화된 백색도-황생도 지수는 풍화단게를 지시해 줄 수 있는 유용한 지시자로 제안되었다. Fresh and weathered granitic rocks of grades Ⅰ to Ⅵ were sampled systematically from six stone and aggregate quarries in four chosen areas in consideration of their textures. In addition to the observed variations. of physical and chemical properties of granitic rocks in terms of weathering grades(Min et al., 1998), slake durability and color index variations were measured and discussed in this article. In the slake durability test, generally with increasing test cycles the granitic rocks of grades Ⅰ to Ⅲ show linear losses of weight but those of Grades Ⅳ to Ⅴ show curvilinear trends, and the fine-grained weathered granitic rocks have comparatively higher durability. As weathering proceeds, whiteness of rocks decreases and yellowness increases. A normalized whiteness-yellowness index is suggested as a weathering index to be one of useful indicators of weathering grades.

서울시 도시공간구조의 동적성장체계에 관한 연구(1987~2002년) : 독시아디스의 ‘동적도시(Dynapolis)’개념을 중심으로 with concept of the ‘Dynapolis’ by C A Doxiadis

서민호,양동양 대한건축학회 2005 대한건축학회논문집 Vol.21 No.1

The purposes of this study are to investigate the applicability of concept of 'Dynapolis' by C A Doxiadis, and to examine the dynamic-growth system of urban spatial structure In Seoul for 1987~2002 The analysis of this study draws on the Population and Economic Censuses each year and a number of statistical sources to explore the change about employment, industry location and commuting mobility In Seoul in the period of 1987-2002 The results show that Seoul has had the multiple compound of linear dynamic growth systems of the 1 class(Manufacturing Industry) and 3 class(FIRE and Higher Producer Services) by L Q (Industry Location Quotient) and S C (Specific Centrality Score) using O/D matrix Also, the result "how that the growth and decline of new and old center of linear growth axis in Seoul had been processed continuously through interactions of each influence-field In detail, as the assumption of the adjusted concept of the 'Dynapohs', Seoul has had the diverse growth-axis with industnal specialization In two classifications Guro-Sungdong axis(past and present) and Sungdong-Dongdaemoon-KwangJin axis(present and future) In case of the 1 class(Manufacturing Industry), Chung-gu(or CBD region)-Yongdeungpo-Kangnam axis(past and present) and Kangnam-Yongdeungpo axis(present and future) In case of the 3 class(FIRE and I ligher Producer Services) Finally, the result of this study corresponds to assumed concepts, 'Dynamic-Growth City(or the adjusted concept of the 'Dynapolis')', and the spatial structure of Seoul consists of the multiple compounds of each dynamic growth system as the structural classification of industry

해양 갈조류를 생물흡착제로 이용한 납흡착 특성 연구

서정호,감상규,오영희,이동환,이민규 동의대학교 기초과학연구소 1998 基礎科學硏究論文集 Vol.8 No.1

Lead sorption performances by biomass of nonliving, dried marine brown algae Undaria pinnatifida, Hizikia fusiformis, and Sargassum fulvellum used as biosorbent materials were investigated. As the amount of biosorbent materials added was increased, the lead removal by biosorbent materials increased but the lead biosorption capacities decreased. However, with increasing initial lead concentration the lead biosorption capacities by the biosorbent materials increased but lead removal efficiencies decreased. In the range of initial lead concentration(C_0) 10-500 mg/L the lead biosorption capacities and removal efficiencies by the biosorbent materials increased with increasing pH. Among the biosorbent materials used in this study, the lead biosorption capacities decreased in the following sequence: U. pinnatifida $gt; H. fusiformis $gt; S. fulvellum. The lead biosorption by biosorbent materials were expressed by the Langmuir isotherm better than the Freundlich isotherm. The biosorption rate could be expressed by the first order reaction rate equation for initial lead concentration like that r_ad = 0.288C_0 for U. pinnatifida, r_ad = 0.255C_0 for H. fusiformis, and r_ad = 0.161C_0 for S. fulvellum.

유연한 관내에서 유량과 벽면횡단압력의 변화에 의한 압착현상에 대한 연구

서상호,조민태 崇實大學校 2000 論文集 Vol.30 No.1

The collapsible phenomena of the circular tubes due to the excessive transmural pressure are investigated experimentally. Collapsible tubes are installed in the test section where the external pressure is applied to the test tubes by applying the hydrostatic head. The collapsible circular tubes are made of rubber, whose diameters are 6 and 4.2 ㎜, respectively. The hydrostatic water head of the upper reservoir is applied to the test section. Pressures at the upstream and downstream sides are measured by the pressure transducers. The collapsible phenomena are observed as the transmural pressure increases, and also the flutter phenomenon occurs due to the critical transmural pressure.

통년성 알레르기성 비염(Perennial allergic rhinitis)에 대한 아크리바스틴(Semprair)^(�)의 임상효과

김민식,신민호,조승호,서병도 최신의학사 1992 最新醫學 Vol.35 No.2

간질환자의 출생 순위에 관한 임상적 연구

이민수,조숙행,한선호,서광윤,이병윤 大韓神經精神醫學會 1981 신경정신의학 Vol.20 No.2

To provide data on the clinical issues related to the birth order and other characteristic background in epilepsy, 331 idiopathic epileptic patients were evaluated and analyzed phenomenologically. The patients had been treated at the neuropsychiatric department of the Korea University Hospital during 1974 to 1980. The age at onset ranged from 1 to 45 years, with the mean age of 16.65 years. Males were 1.36 times more than females. Seventeen (5.13%) of the subjects had the family history of epilepsy. Attacks in the daytime only occurred in 67.67% (N=224) of the subjects, while 23.56% (N=78) had their seizures only at night, and 8.77% (N=20) had their seizures both at daytime and night. Grand mal was the most frequent type of seizure, followed by psychometer and petit mal. There was a higher incidence among the first born than the subsequent siblings and the children born second had a somewhat higher frequency of epilepsy than the subsequent children.

Angiolymphoid hyperplasia with eosinophilia associated with arteriovenous malformation

Seong Min Kang,Woo Jin Lee,Myoung Shin Kim,Chong Hyun Won,Sung Eun Chang,Ho Seok Suh1,Mi Woo Lee,Jee Ho Choi,Kee Chan Moon 대한피부과학회 2009 대한피부과학회 학술발표대회집 Vol.61 No.1

난치성 만성정신분열증 환자의 생활의 질에 미치는 정신사회치료 프로그램의 효과에 대한 예비연구

송동호,배민진,이종호,이홍식,김선경,서호석,김찬형,전지용 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.4

Objects : Recent studies of psychosocial adjustment after hospitalization have found that the combination of maintenance antipsychotic drug treatment and psychosocial treatment including psychoeducational program are highly predictive of social rehabilitation and reduction of subsequent relapse. Two groups of patients with refractory chronic schizophrenia were preliminarily compared to determine the effect of a psychosocial treatment program on the quality of life in refractory chronic schizophrenics in an open comparative trial. Methods : One group(N=11) was assigned to approximately six months of the psychosocial treatment program(including psychoeducation program and activity program such as interpersonal relationship program, social skill training, self management program, outings, etc), in a group format, twice a week and a fixed maintenance dosage of clozapine ; while scale(QLS) was used to provide an objective measure of changes in patient's psychosocial functioning and a general assessment of psychopathology was made using the Brief Psychiatric Rating Scale(BPRS). Results : Both BPRS total positive score and the QLS total score, especially in the intrapsychic foundation factor of the scale showed a statistically significant improvement in the psychosocial treatment group. But there was no significant change in both BPRS and QLS scores over a 6-month period in the non-psychosocial treatment group. A significant negative correlation was found between the negative symptom and changes of QLS total, instrumental role and common object and activities scores respectively after receiving a 6-month of the psychosocial treatment program. Conclusion : These results suggest that a psychosocial treatment program including the integration of psychoeducation and a skill training oriented activity program serve as an outpatient treatment modality to improve the quality of the life in refractory chronic schizophrenia. To further clarify the effect of psychosocial treatment in chronic schizophrenia, a randomized trial should be done.