Gene pyramiding effect of two major bakanae disease resistance gene using qBK1 and qBKWD

Sais-Beul Lee,Tae-Heon Kim,Su-Min Jo,Jun-Hyun Cho,Ji-Yoon Lee,Jong-Hee Lee2,Dongjin Shin,You-Chun Song,Myung-Kyu Oh,Dong-Soo Park 한국작물학회 2017 한국작물학회 학술발표대회 논문집 Vol.2017 No.-

전격성 경과를 취한 만성 호산구성 폐렴 환자 1예

윤호상,진춘조,유광하,이상엽,이수인,정상만,김선두,이순제,이길도,전혜정 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

Chronic eosinophilic pneumonia(CEP) is a rare disease of unknown etiology characterized by chronic infiltration of the lung with eosinophils. It presents with profound systemic symptoms comprising fever, night sweats, weight loss, dyspnea and blood eosinophilia with nonsegmental air-space consolidation confined to the outer third of the lung, the "photographic negative of pulmonary edema". Histopathologic features of chronic eosinophilic pneumonia are intraalveolar and interstitial infiltrations with eosinophils, histiocytes, giant cells, scattered lymphocytes and plasma cells. Glucocorticoid therapy cause prompt resolution of symptoms as well as disappearans of blood eosinophils, elevated serum Ig E levels and the roentgenographic lesions. Infrequent radiographic findings include nodular infiltrates, consolidations, cavitations, atelectasis and pleural effusions. Deaths from CEP although rare, have been reported, but the majorities of CEP have benign courses and do not need a therapy with ventilator. We report a case of chronic eosinophilic pneumonia, which had a sudden course associated with diffuse pneumonic consolidations on the both lung and bilateral pleural effusion.

Genetic Characterization of Haemagglutinin 1 Domain of Influenza B Viruses Isolated in Korea during $1988{\sim}1999$

Shin, Gu-Choul,Na, Byoung-Kuk,Lee, Joo-Yeon,Ahn, Jung-Bae,Park, Jong-Won,Lee, Jin-Soo,Kim, Jee-Hee,Kim, Woo-Joo,Kang, Chun The Korean Society for Microbiology 2003 Journal of Bacteriology and Virology Vol.33 No.4

Although Korean influenza virus isolates have been genetically associated with the vaccine strains of the corresponding year, influenza B viruses have prevailed almost every year in Korea during the past decades. We have 'analyzed the genetic characteristics and evolutionary patterns of the haemagglutinin (HA) 1 domains of influenza B viruses isolated during 1988-1999 using direct RT-PCR and sequencing. Phylogenetic analysis of influenza B viruses isolated in Korea indicated that antigenically and genetically distinguishable strains of the lineage II and lineage III variants had been cocirculated. Variants prevailed in early 1990s are represented in 1996/97 and 1998/99 and some different variants have been co circulated geographically and prevailed concurrently in Korea. All HA1s of Korean isolates have amino acid substitutions mainly in the region between position 124 and 310, which was previously proposed an immunodominant region. Insertion-deletion patterns of the HA gene revealed that Korean influenza B viruses were evolved from Lee40 with different manner between lineage II and III viruses. Lineage III viruses were also divided into two groups as conserved group and inserted group, in relation to Lee40. But lineage II viruses had evolved with directional pattern. Antigenic index proposed that influenza B isolates prevailed since 1996/97 seasons might had emerged from the antigenic variants of a Seo1697-like virus and that new variants might appear from the lineage II viruses resulting in persistent prevalence in Korea.

여성들의 화장실태와 화장지식 및 화장태도에 관한 연구

이승자,전용수,김장순,이종열,박천만 한국미용학회 2001 한국미용학회지 Vol.7 No.3

This study was conducted to provide the basic data necessary to develop the academic make-up program by analysing women' s make-up state, knowledge degree and attitude toward their make-up, and elements having an effect on their make-up attitude, using questionnaires answered by women who visited the 22 sampled beauty shops in Daegu from March 15 to April 4, 2001. The analysed result of this study is summarized as follows. 1. Based on the general features of sampled subjects, it was shown that the age of 21∼30 years old accounted for 45.7% and 31∼40 years old for 24.5%, and graduation from junior college or higher educational background for 54.8% and high school or higher for 41.8%. Their occupational fact showed that nonoccupation including full-time housekeepers accounted for 25.7% and experts for 25.2%. The result of marriage status indicated that the single accounted for 55% and the married for 41.1%. Their body status showed that the underweight accounted for 30.5% and overweight or fatness for 10.7%. Their answers about health status indicated that poor health accounted for 30.0% and good health for 14.8%. Their skin health status was that poor skin type accounted for 33.4% and dry skin type for 30.7%. Their average knowledge about make-up was 65.2 marks, and 54.1% of all the subjects had less knowledge than the average marks. 2. Their reasons for make-up indicated that 'to be beautiful' accounted for 29.8% and 'to have good manners as women' for 26.1%. With respect to their age, it was shown that the young women below 30 years old tended to make up 'to be beautiful(34.3 - 35.0%) while women above 41 years old did to have good manners as women(49.3%). Then, it was also shown that the respondents with high education level(p<0.001)and occupation including students(p<0.01), and the single(p<0.001) tended to make up 'to be beautiful' while the women with low education level(p<0.01) and with no occupation(p<0.01), and the married women(p<0.001) did 'to have good manners as women' to protect skin' or 'to cover weakness' . 3, The technical level of make-up they answered was that Not bad' accounted for 49.0% and 'Bad' for 33.0%. The respondents with the age below 20 years old(p<0.05), education level lower than a middle school(p<0.05), overweight and fatness(p<0.05), poor skin status(p<0.01) and less knowledge about make-up(p<0.001) showed bo not make up well' 4. The subjects answered about the importance of make-up that 'Yes' accounted for 48.9% which was higher than 10.9% of No The more the age and knowledge and with occupation, the higher the importance (p<0.01). 5. Their satisfaction level with make-up indicated that unsatisfaction(25.5%) was higher than satisfaction(21.8%). The worse the health state and skin health status, the higher the unsatisfaction(p<0.001) 6. Their frequency of shaded make-up indicated that 'Everyday accounted for 38.2% and 'Nearly not for 27.9%. It was also shown that the more the age(p<0.05) and with occupation(p<0.05) and knowledge about the make-up(p<0.05), the higher their tendency to make up everyday while the lower the age(p<0.05), the lower their tendency of make-up, and the students(p<0.05) nearly did not make up. 7. Whether or not their cosmetic has been selected after the consideration of skin type showed that 73% of the subjects responded 'Yes' which was higher for the persons with the age of 21∼30 years old(p<0.05), high education level(p<0.05) and more knowledge about the make-up(p<0.05). 8. Concerning the question about whether or not they have participated in any make-up education program, it was shown that 59.3% had no any experience in participation which was higher for the persons with no job(p<0.001), in general employment state(p<0.001), and with less knowledge about make-up(p<0.01). 9. The subjects who answered their spending ￦20,000∼40,000 on cosmetics every month accounted for 45.9% which was highest. It was shown, then, that the women with more age(p<0.001), with job(p<0.001) and with dry skin type(p<0.01) tended to spend more money. 10. Based on the question concerning their way to get information about cosmetics, it was shown that 'from professional cosmetic magazines' accounted for 32.7% and 'from TV or from newspapers' for 27.3%, and that the women with the age below 30 years old(p<40.8%) and in unmarried status(p<41.8%) obtained mainly the information 'from professional magazines' . The women with the age of 30 years old(31.5%) preferred 'from TV or from newspapers while the women with more than 41 years old(42.3%) and in married status(32.6%) did 'from beauty shops or from cosmetic saleswomen' (p<0.001). 11. Their degree of knowledge about make-up showed that the higher their education level, the higher their degree of knowledge, and that the degree was lower for the women with education level below graduation from a middle school(p<0.01) and overweight and fatness(p<0.01). 12. Their attitude toward make-up indicated that the women with professional job(p<0.01) and more knowledge about make-up(p<0.001) were positive. 13. In order to analyse elements influencing an attitude toward make-up, a multiple regression analysis was done by considering their attitude as a dependent variable, and their general features and make-up state as an independent variable. As a result, it was shown that the higher the degree of importance they think about make-up(p<0.001), the longer the time they take for make-up(p<0.001), the more their knowledge about make-up(p<0.01), the more their age(p<0.05) and the more their experience in participation in make-up education programs(p<0.05), the higher the degree they were positive toward make-up. The make-up is an essential action for women to express their aesthetic sense, and has an important effect on their making a healthy living socially and mentally, as well as on their skin health. Even though many women have understood the importance of make-up and have made up everyday, it appeared that their knowledge about make-up and make-up technique were insufficient, which mean needs for a systematically organized make-up education. To do that, it is required to first develop a synthetic program designed for the systematic make-up education.

알레르기 환자에서 특이알레르겐 항체 양성율과 관련요인

이선화,남해선,이성수,안현철,황규윤,박준수,,박춘식 순천향의학연구소 2002 Journal of Soonchunhyang Medical Science Vol.8 No.2

Recently, allergic diseases are very prevalent in Korea, resulting in physical and economic losses during the life. It is well-known that the principle therapy is identification, eradication, and desensitization of allergens. There are many allergic diagnostic tools for identification of specific-allergens. However, none of them is satisfied with its efficiency due to lack of validity. Recently MAST-CLA has been widely used in the allergic clinical fields because of its simplicity and simultaneous identification of allergens. This study was designed to determine the positivity of allergen-specific antibodies using MAST-CLA in patients with allergic diseases, and evaluate the efficacy for allergen detection, compared to results of skin prick test. During June 2000 - September 2001, 325 study subjects visited Soonchunhyang University Chunan Hospital for the evaluation of allergic problems. Among them, 289 subjects were diagnosed with allergic disease and included for the study. Thirty four subjects visited children's allergic unit were evaluated specific allergens using a skin prick test at the same time. Our result as follows; 1. The positive rates of allergen-specific antibodies and total IgE were 51.2% and 73.4%, retrospectively. 2. There was significant difference in positive rate in age group, showing highest in teen ages(73.6%), but insignificant difference in sex in allergen-specific antibodies. 3. The positive rate was 60.4% in allergic rhinitis, 51.3% in allergic dermatitis, 46.9% in bronchial asthma, and 39.1% in urticaria in order(P=0.073). 4. Significant difference in month or season was observed, with highest rate in April(78.1%) and May(72.1%). The highest season was in spring(62.7%), and then summer(52.8%), fall(50.3%), and winter(41.4%) in order (P=0.04). 5. The three highest allergen-specific antibodies were D. pteronyssinus(39.3%), D. farinae(38.3%), and house dust(24.3%) in Korean inhalant pannel, However, in food pannel types of allergen-specific antibody were different as D. farinae(18.5%), Alternaria(18.5%), house dust(17.3%). 6. There were significant agreements between MAST-CLA and Skin prick test (D. farianae Kappa=0.636;D. pteronyssinus Kappa=0.78, both P<0.001) In conclusion, MAST-CLA could detect allergen-specific antibodies in patients with allergic diseases as a simple and valid tool of screening of allergy. Especially, it could be a useful measure of multiple allergens simultaneously in children However, more detailed allergens and valid assay for unmeasured allergens should be identified for Korean-specific allergens.

국내에서 유행하는 HIV의 전파 경로에 따른 Subtype 분포

이주실,남정구,김성순,강춘,최병선,김옥진,박미선,성봉모,서순덕,전수경,변승옥,신영오,조해월 대한감염학회 2001 감염 Vol.33 No.5

Background : Previous data have been reported that subtype B is prevalent in South Korea, but neither the extent nor the proportion of subtypes could be evaluated. This study was designed to analyze the distribution of HIV-1 subtypes, temporal instructions and transmission dynamics between epidemiological groups. Methods : 1,280 Koreans had been diagnosed as HIV seropositive during the period 1985 to 2000. Among them, 134 individuals were selected for this molecular epidemiological study. 134 DNAs were isolated from uncultured or cultured peripheral blood mononuclear cells. V3-V5 (0.7 kb) fragment of HIV-1 env gene was amplified by nested polymerase chain reaction and was sequenced. Results : HIV-1 isolates from thirty-seven homosexuals were all subtype B (100%). On the other hand, 66 isolates from 94 heterosexuals were subtype B (70%) and 28 were non B subtypes (30% : 13 A, 4 C, 2 D, 8 E , 1 G). Only subtype B strains were isolated from 73 males who were infected with HIV inside Korea while 16 B and 20 non B subtype strains were isolated from 36 males who were HIV infected outside of Korea. However, B and non B strains were isolated half and half from females who were infected inside Korea except one. Conclusion : The HIV-1 subtype B strains are prevalent in Korea from the early HIV infection until present in both homo and heterosexuals. Non B strains have been transmitted from men who were infected outside Korea to their spouses and casual partners. So, we need further study to monitor subtype B and non B HIV transmission in epidemiological groups of Korea, (Korean J Infect Dis 33:311∼318, 2001)

마늘의 동결건조 과정중 ALLICIN 성분변화에 관한 연구

이명환,채수규,전문진 고려대학교 자연자원대학 1995 자연자원논집 Vol.35 No.2

AlIium속 식물인 마늘을 생것인 상태 및 이들을 통째로, 얇게 썰어서 또는 다져서 동결건조처리에 따른 allicin을 포함한 유용성분의 함량변화와 allinase의 효소활성을 측정한 결과는 다음과 같다. 1. 시료의 전처리 방법에 따른 allicin과 dially1 disulfide의 함량은 생 것인 상태, 통째로 및 얇게 썰어서 및 다져서 동결건조시킨 순으로 감소하는 경향을 나타내었으며, 다져서 동결건조시킬때 약 35.3%의 allicin감소를 나타내었다. 2. pyruvate 함량을 시료 중량대비로 측정한 결과 생것인 상태보다는 통째로, 얇게 썰어서 및 다져서 동결건조시킨 순으로 증가하는 경향을 나타내었다. 3. 마늘의 동결건조방법에 따른 allinase 활성을 측정한 결과, 생마늘의 allinase 비활성은 7.422units/mg protein이었으며, 통째로, 다져서 및 얇게 썰어서 동결건조시킨 순으로 감소하는 경향을 나타내었다. 4. 동결건조시간 경과에 따라서 마늘을 통째로, 다져서 및 얇게 썰어서 동결건조시킬때, 수분함량이 감소하고, allinase활성은 감소한 반면에 puruvate의 함량은 증가하였으며, thiosulfinate 함량은 시간경과에 따라서 감소하는 경향을 나타내었다. The purpose of this study is to investigate changes in the amount of useful compounds including and in the enzyme activities of alliinase as a result of freeze-drying treatment of garlic in whole, sliced or crushed state. The results obtained are as follows: 1. The amount of allicin and diallyl disulfide was decreased: the degree of decrease was in the order of raw, freeze-dried whole, freeze-dried sliced and freeze-dried crushed. Garlic showed 35.3% allicin decrease almost 100% when they were freeze-dried crushed 2. The amount of pyruvate was increased: the degree of increase was in the same order as above. 3. The activity of allinase was reduced as a result of freeze-drying treatment: the degree of reduction was in the order of whole, crushed and sliced. The activity of allinase in raw garlic was 7.422units/mg protein. 4. When garlic was freeze-dried as whole, crushed or sliced, the amount of water and the activity of allinase decreased while the amount of pyruvate increased as time passed. And the amount of thiosulfinate tends to decrease as time passed.

용지 호수공원의 수질관리 방안에 관한 연구

이춘수,서규태,문병현,이택순 7개 국립대학교 환경연구 논문집 공동발행 위원회 2003 공업기술연구 Vol.3 No.-

This study was performed for water quality management of Yonggi Lake Park in Changwon City. The results are as follows; The water quality of the lake was deteriorated during summer season because of algal blooming. It was estimated that existing treatment capacity of the lake water was not sufficient to meet the target lake water quality. And so the lake water circulation period, 40 days should be shorten to below 30 days by increasing the treatment capacity. Fountain and air supply facilities for 02 supply and mixing caused rather resuspension of solid settled at the bottom of the lake. It was also evident that the extended detention of water in the lake resulted in water quality deterioration. Consequently it is important to supply high quality water from other sources. Especially lower temperature water had better effect on improvement of the water quality.

공구 수명의 신뢰성 예측 프로그램 개발

이수훈,김봉석,강태한,송준엽,강재훈,서천석 한국공작기계학회 2004 한국공작기계학회 춘계학술대회논문집 Vol.2004 No.-

This paper deals with a prediction method of tool life in view of the reliability assessment. In this study, the flank wear was studied among multi-factors deciding the tool wear state. Firstly, tool life was predicted by correlation between flank wear and cutting time, based on the extended Taylor tool life equation of turning data, including parameters of cutting speed, feed rate, and cutting depth. Secondly, each of cutting conditions of endmilling was equivalently converted to apply ball endmill data to the extended Taylor equation. The web-based reliability prediction program for tool life is being developed as one of reliability assessment programs to for the machine tools.

Tennis競技에 있어서 net play의 得失에 關한 分析

李秀川 慶北大學校 體育科學硏究所 1985 체육과학연구지 Vol.1 No.-

The object of this study is to analyze the elements of the ace and miss in the tennis net play. The materials for this study were collected from three national tennis tournaments. The results of materials are as follows; 1. The difference between winners and losers was not high in serve and net play, but also, a high rate of point abtained by the opponent. 2. Thought there was a little difference between winners and losers, The approach shot made a great rate in the order of BCS, FSS, FCS in male high school and BCS, FSS, FCS in male adults game. It was found that net players were used to stroke deeply the opponent back side. 3. Considering the total obtained by net play, male high school was shown that winners was 49.0% and losers was 47.6%, The other side, 55.0% (winners), 55.9%(losers) in the game of male adults. Therefore, the latter is more offensive opration of game than the former according to the talle 11. 4. abstraitding 1,2, and 3, first, the game management must progress the net dash after serve, second, the players must dash with the attention of lob, the importance of smash and the direction of stroke.