열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

원발성 유방암에서 Sodium Iodide Symporter의 발현과 ^(99m)Tc-MIBI 유방스캔의 관계

석주원,김성장,곽희숙,이창훈,김인주,김용기,배영태,김동수 대한핵의학회 2002 핵의학 분자영상 Vol.36 No.6

목적: hNIS는 갑상선 조직 외에 다른 조직들에서도 발현된다고 알려져 있다. 유방암 세포는 그런 조직들 중에 하나이며, 그에 의한 유방암의 방사성옥소치료의 가능성이 제시되고 있다. 본 연구에서는 유방암 조직에서 hNIS의 발현정도를 알아보고, ^99mTc-MIBI 유방스캔과 hNIS의 발현 정도와의 관계를 조사하여 보았다. 대상 및 방법: 본 연구에서는 유방암으로 수술을 시행했던 56명의 환자를 대상으로 하였다. hNIS의 발현은 면역조직화학염색에 의해서 평가되었으며, 그 결과를 ^99mTc-MIBI 유방스캔의 판정 결과와 비교하였다. 결과: 전체 56명의 환자에서 hNIS의 발현율은 41.1%였다. 병리학적 진단에 의해 침윤성관상피암종이었던 49명에서의 발현율은 42.9%, 관상피내암종이었던 7명에서의 발현율은 28.6%였다. ^99mTc-MIBI 유방스캔에서 국소섭취 소견이 관찰되었던 41명에서의 hNIS의 발현율은 31.7%였다. 비정상적인 섭취 소견이 관찰되지 않았던 15명의 환자에서의 hNIS의 발현율이 의미있게 높게 관찰되었다(66.7%, p>0.05). 결론: 유방암 환자에서의 hNIS의 발현율은 그다지 높지 않았다. ^99mTc-MIBI 유방스캔에서 섭취증가 소견이 없을 때 hNIS의 발현율이 더 높았다. Purpose: Human Na^+/I- symporter (hNIS) is known to be expressed in many tissues other than thyroid gland. The breast cancer cells are one of them and the possibility of radioiodine therapy in treatment of the breast cancer may be suggested. We investigated the expression rate of hNIS and the relationship between the expression of hNIS and the finding of 99mTc-MIBI scintimammography in the breast cancer. Materials and Methods: Surgically proved 56 patients with breast cancer were the subjects of this study. The expression of hNIS were evaluated by immunohistochemistry and the results were compared to the findings of 99mTc-MIBI scintimammography. Results: Overall expression rate of hNIS was 41.1% in 56 patients. According to the pathologic diagnosis, it was 42.9% in 49 patients with invasive ductal carcinoma and 28.6% in the 7 patients with ductal carcinoma in situ. The expression rate of hNIS in the 41 cases with a focal increased uptake at he breast lesion on 99mTc-MIBI scintimammogram was 31.7%. That in the 15 cases without any abnormal uptake on the scan was significantly higher(66.7%, p<0.05). Conclusion: The expression rate of hNIS in the patients with breast cancer was not so high. The rate was higher in the patients with no increased uptake at the breast lesion on 99mTc-MIBI scintimammography. (Korean J Nucl Med 2002;36;325-32)

ILQ 제어를 이용한 열간압연 폭 제어시스템 개발에 관한 연구

김성배,황이철 동의대학교 산업기술개발연구소 2001 産業技術硏究誌 Vol.15 No.-

This paper studies on the design of a ILQ(Inverse Linear Quadratic optimal control) looper control system for hot strip mills. The looper which is placed between each stand plays an important role in controlling strip width by regulating strip tension variation generated from the velocity difference of main work rolls. The mathematical model for looper is firstly obtained by Taylor's linearization of nonlinear differential equations, where it is given as a linear and time invariant state-space equation. Secondly, a looper servo controller is designed by ILQ control algorithm, which is an inverse problem of LQ(Linear Quadratic optimal control) control. By tunning control gain arbitration parameters and time constants, it is shown that the ILQ looper servo controller has the performance that makes well to follow desired trajectories of both strip tension and looper angle.

적외선 열화상 카메라를 이용한 고속가공에서의 열 발생 특성

김흥배,이우영,최성주,유중학 한국공작기계학회 2001 한국공작기계학회 춘계학술대회논문집 Vol.2001 No.-

The term 'High Speed Machining' has been used for many years to describe end milling with small diameter tools at high rotational speeds, typically 10,000 - 100,000 rpm. The process was applied in the aerospace industry for the machining of light alloys, notably aluminium. In recent year, however, the mold and die industry has begun to use the technology for the production of components, including those manufactured from hardened tool steels. With increasing cutting speed used in modern machining operation, the thermal aspects of cutting become more and more important. It not only directly influences in rate of tool wear, but also will affect machining precision recognized as thermal expansion and the roughness of the surface finish. Hence, one needs to accurately evaluate the rate of cutting heat generation and temperature distributions on the machining surface. To overcome the heat generation, we used to cutting fluid. Cutting fluid play a roles in metal cutting process. Mechanically coupled effectiveness of cutting fluids affect to friction coefficient at tool-work-piece interface and cutting temperature and chip control, surface finish, tool wear and form accuracy. Through this study, we examined the behavior of heat generation in high-speed machining and the cooling performance of various cooling methods.

멀티 프레임 PRA를 이용한 움직임 추정

김형종,이성순,최영일,조금배,한승조 조선대학교 동력자원연구소 1997 動力資源硏究所誌 Vol.19 No.1

We discuss the theory of motion estimation and motion compensation. The proposed algorithm uses more information from the input video image sequence than the traditional two-frame pel-recursive algorithms. And it uses fewer assumptions on the motion vectors among different video frame pairs. This paper shows two three-frame pel-recursive algorithm for predictive motion compensation which can estimate the d₁(from the previous frame f_t-1 to current frame, f_t) and d₂(from the frame before the previous frame f_t-2 to the previous frame, f_t-1) simultaneously, and three frame information to update the motion vector d₁when the past motion vector d₂is available.

CO₂고정을 위한 화학독립영양미생물 Aeromonas sp. strain JS-1의 분리 및 특성

배상옥,곽경오,이용운,김성준,정선용 전남대학교 촉매연구소 2000 觸媒硏究 論文集 Vol.21 No.-

The increase of CO2 in the atmosphere by fossil-fuel combustion has been recognized as a major cause of global warming. Thus many studies on CO2 removal from the combustion gas have been performed, and recently the techniques for biological CO2 fixation by photoautotrophs have also been developed, In this study, extensive screening was conducted to obtain micoorganism with high capability in fixing CO2, and its characteristics was investigated. As a result, a chemoautotrophs identified as a Aeromonas sp. strain JS-1 was isolated from the fresh water. The isolated strain used the molecular hydrogen and CO2 as an energy and a carbon source, respectively. Growth characteristics, which will be used in the development of a continuous culture system related in CO2 fixation, were examined in batch cultivation under conditions of various CO2 and NaCl concentrations, temperature, and pH. The results of the examination showed that the isolated strain had a good growth to high CO2 concentration(40%), indicating applicable in removing CO2 discharged from industries.

산화와 환원반응의 연계성에 관한 연구

김효겸,문정대,문성배 부산대학교 사범대학 과학교육연구소 1997 科學敎育硏究報 Vol.24 No.-

The content of oxidation-reduction in the chemistry textbooks from middle school to college was analyzed to see the effective connection of curricular articulation. For this purpose, oxidation-reduction content between the school unit were selected in chemistry textbooks and formed five types of classification from groups of "first concept", "same concept", "overlap", "development" and "gap". The result indicated that there was a deep big gap from middle school to senior high school and the effectiveness from senior high school to college was looked acceptable. Finally, the new concept maps between the school unit were suggested.

M-Commerce에서 Secure Card 기반의 결제 프로토콜 설계

김성열,조성지,유성진,배용근 조선대학교 전자정보통신연구소 2002 電子情報通信硏究所論文誌 Vol.5 No.2

In order to provide a reliable M-Commerce, a payment solution with security functions should be required. User's mobile terminals used in M-Commerce services are diversifying to cellular phone, PDA, Smart phone etc. Among them, integration of PDA's interface and mobile connection overcomes the weak point of existing cellular phone depending on information via the internet. In this paper, the Secure Card based protocol for a credit card transaction on PDA using ECC is presented. Secure Card module on this protocol encrypts user's information such as private information, delivery information and credit card information and stores it on PDA in order to free from inputting information whenever it is used. This scheme also offers security services on M-Commerce including authentication, confidentiality, integration, non-repudiation and so on.

정수공정에서 이취미물질 제거에 관한 연구

김지태,한명애,곽현,배성렬 漢陽大學校 工學技術硏究所 2000 工學技術論文集 Vol.9 No.1

이취미물질중에서 페놀, Geosmin, 2-MIB를 선정하여 응집제(PACS)와 흡착제(PAC) 및 산화제(Cl2, ClO2)로 처리하였을 때 제거율을 알아보았다. 페놀의 경우 이산화염소(ClO2)와 분말활성탄(PAC)으로 처리하였을 때 제거효율이 높았고, Geosmin과 2-MIB는 분말활성탄(PAC)으로 처리하였을 때 제거효율이 높았다. 그러나 페놀, Geosmin, 2-MIB 모두 응집제(PACS), 염소(Cl2)로 처리하였을 경우에는 제거효율이 거의 없음을 알 수 있었다. The removal ratio of phenol, geosmin, and 2-MIB selected in odor and taste causing materials was investigated, when water was treated with coagulant(PACS), adsorbent(PAC), and oxidants(Cl2, ClO2). Phenol was removed at a relatively higher rate by the treatment with CIO2 and PAC(Powder Activated Carbon). The other side, geosmin and 2-MIB were removed at a higher rate by the treatment with PAC. But it was found that the treatment with coagulant(PACS) and chlorine(Cl2) for the removal of phenol, geosmin and 2-MIB was little removal efficiency.

고속가공에서 박막 측벽(Thin wall) 파트 가공을 위한 연구

김홍배,이우영,최성주 한국공작기계학회 2000 한국공작기계학회 추계학술대회논문집 Vol.2000 No.-

The term 'High Speed Machining' has been used for many years to describe end milling with small diameter tools at high rotational speeds, typically 10,000 - 100,000 rpm. The process was applied in the aerospace industry for the machining of light alloys, notably aluminium. In recent years, however, the mold and die industry has begun to use the technology for the production of components, including those manufactured from hardened tool steels. And the end-mill is an important tool in the milling process. A typical examples for the end mill is the milling of pocket and slot in which a lot of material is removed from the workpiece. Therefore the proper selection of cutting parameters for end milling is one of the important factors affecting the cutting cost. The one of the advantages of HSM is cutting thin-wall part of light alloy like Al (thinkness about 0.3㎜). In this paper, firstly, we study characteristics of HSM, and then, we choose the optimal parameters(cutting forces) and investigate various machining strategies to cut thin-wall part by experiment.