개의 대퇴골간에서 발생한 유합부전의 1례

강은경,조성환,류시윤,손화영 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

Fracture healing is a complex physiological process that involves the coordinated participation of several cell types. Unlike other tissues that heal by the formation of poorly organized scar, in fracture healing the original tissue, bone, is regenerated and the properties of the preexisting tissue largely are restored. Fracture healing generally proceeds in an orderly fashion when appropriate biological and mechanical component are present. Many complications may occur with repair and subsequent healing of fracture, including osteomyelitis, implant loosening, and fracture instability. All of these complications may result in delayed union, nonunion or malunion of the fracture. A 1-year-old male, Collie sustained a closed, transverse femoral fracture in a mortor vehicle accident. His initial treatment with open reduction and bone plating was failed. A second surgery was done to remove the plate and perform corrective osteotomy, and bone grafting. Histopathological observation of the bone fragment from fracture end was carried.

개에서 심장사상충과 유선암종 합병증의 1예

조은상,손화영,류시윤,조성환 忠南大學校 獸醫科大學 動物醫科學硏究所 2005 動物醫科學硏究誌 Vol.13 No.-

A dog which referred to animal hospital with chief compliment of left hindlimb lameness, was died under the examination, so we observed this case histopathologically. Clinical signs were hindlimb lameness, dyspnea, exercise intolerance, lethargy, hemoptysis, anorexia, and coughing. The gross findings were 5cm in diameters nodule in the caudal abdomen, swelling and milky nodules of the lung, swelling and gray-white patches of the liver, ovarian cyst and dirofilariasis in the heart. In histopathologic examination, metastatic tumors and microfilaria were observed in the lung, liver, spleen, adrenal gland and kidney.

버스정보시스템(BIS)을 위한 모바일 환경의 시각화 기법 연구

박동규,박진화,이수진,박은호,류동성,어윤 국립7개대학공동논문집간행위원회 2004 공업기술연구 Vol.4 No.-

In this paper we describe a visualization method for Bus Information System(BIS) on Mobile Environment. A BIS is a key service for Intelligent Transport System(ITS) on public transportation area. We present a client-server based visualization technique for bus route information over Internet Protocol and user-oriented regional information service with a voice and animation. We also describe the design and implementation of this kind of schematic map generation system with icon and label.

건강가정지원센터 가정생활교육 프로그램 운영 및 성과 : 용산구·숙명여자대학교 시범사업을 중심으로

김명자,계선자,박미석,장진경,김연화,한은주,류진아 한국가족관계학회 2005 한국가족관계학회지 Vol.10 No.1

The purpose of this study is to propose a model for service programs and management strategies for the division of family education in Healthy Families Center. For the purpose, the researchers find out demands for the family education programs of people in Yong-San Gu, Seoul, exam the effect of each family education program of Yong-San Gu & Sookmyung Women's University Healthy Families Center from June to December, 2004. According to the results, people in Yong-San Gu need economic education service mostly, and they want to study at Saturday afternoon. The programs show positive effect on the improvement of family health.

Synthesis and Properties of Hydroquinone Glycosides Synthesized Using Leuconostoc mesenteroides Glycansucrases

Hwa-Ja Ryu,Hee-Kyoung Kang,Eun-Seung Seo,Than Hanh,Go-Eun Kim,Hea-Jin Woo,Nahyun Kim,Young-Min Kim,Doman Kim 한국당과학회 2010 한국당과학회 학술대회 Vol.2010 No.1

In this seminar I will briefly introduce about current research progress in our Lab related with glycoside synthesis using glycansucrases and carbohydase inhibitor screening using Grid. We are synthesizing various glycosides of the hydroquinone for the improvement of antioxidant activity. Hydroquinone (HQ) functions as a skin whitening agent, but it has the potential to cause dermatitis. We synthesized a novel HQ fructoside (HF), HQ galactoside and HQ glucoside as potential skin whitening agents by reacting glycansucrases from Leuconostoc mesenteroides with HQ as an acceptor and sucrose as a donor. The product was purified using butanol partition and silica-gel column chromatography. One of them HF synthesis was determined using a response surface methodology and the final optimum condition was 350-mM HQ, 115-mM sucrose, and 0.70 U/ml levansucrase, and the final HF produced was 1.09 g/l. HF showed anti-oxidation activities and inhibition against tyrosinase. The IC50 of DPPH scavenging activity was 5.83-mM, showing higher anti-oxidant activity compared to β-arbutin (IC50 = 6.04-mM). The Ki value of HF (0.67-mM) against tyrosinase was smaller than that of β-arbutin (Ki = 2.8-mM). The inhibition of lipid peroxidation by HF was 108.12% that of HQ (100%) and much higher than that of β–arbutin (0.81% of HQ). Virtual screening (VS) was applied for discovery of new inhibitors for the human intestinal maltase (HMA) enzyme. VS of 308 307 compounds was performed with HMA using 4700 CPUs and AutoDock 3.0.5 in a WISDOM (Wide In Silico Docking On Malaria) production environment. The 42 best ranked compounds containing hydrogen bond interaction with key residues from VS were tested in vitro for their inhibitory activities against the recombinant HMA from Pichia pastoris. Compounds 17 and 18 were identified as competitive inhibitors for enzyme inhibition with Ki values of 19.8 and 19.6 μM, respectively. In contrast to acarbose, the two compounds showed no inhibition on human pancreatic α-amylase, suggesting potential inhibitors with fewer side effects, including abdominal discomforts.

New classification of late and delayed complications after dermal filler: localized or generalized?

( Hwa Jung Ryu ),( Bo Young Kim ),( Sook In Ryu ),( Song Chang Hwa ),( Joo Yeon Ko ),( Young Suck Ro ),( Il-hwan Kim ),( Jeong Eun Kim ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1

Background: As filler injections have become very common procedures worldwide, the number of complications has increased. However, there is a lack of systematized studies and precise classification of late and delayed complications. Objectives: This study aimed to suggest new and reliable classifications and to characterize the clinical manifestations of late and delayed complications after filler injections. Methods: This retrospective study analyzed patients and suggested a new classification of delayed adverse effects related to filler injection. Several demographic and clinical findings were analyzed. Patients were classified into two types according to their clinical presentation: Type I (Localized) or Type II (Generalized). Results: Twenty-five patients were evaluated during a clinically active adverse event suspected to be related to fillers. The most common injected filler substance was hyaluronic acid (HA, 68.8%). 76% of the patients were classified with Localized complications. In the Generalized complications group, systemic symptoms were more common (p=0.002), the treatment response was poor (p=0.010), and fewer patients showed complete remission (p=0.007) than in the Localized complications group. Conclusion: We propose a simple new classification method for late and delayed complications after dermal filler: Localized and Generalized. We expect that this new classification could help provide appropriate treatment and predict patient prognosis.

KAAACI Guidelines for Allergen Immunotherapy

Lee Hwa Young,이상민,강성윤,Kim Kyunghoon,Kim Ju Hee,Ryu Gwanghui,Min Jin-Young,Park Kyung Hee,Park So-Young,Sung Myongsoon,Lee Youngsoo,Yang Eun Ae,Jee Hye Mi,Ha Eun Kyo,Shin Yoo Seob,Chung Eun Hee,Choi Su 대한천식알레르기학회 2023 Allergy, Asthma & Immunology Research Vol.15 No.6

Allergen immunotherapy (AIT) is a causative treatment for various allergic diseases such as allergic rhinitis, allergic asthma, and bee venom allergy that induces tolerance to offending allergens. The need for uniform practice guidelines in AIT is continuously growing because of the increasing discovery of potential candidates for AIT and evolving interest in new therapeutic approaches. This guideline is an updated version of the Korean Academy of Asthma Allergy and Clinical Immunology recommendations for AIT published in 2010. This updated guideline proposes an expert opinion by allergy, pediatrics, and otorhinolaryngology specialists with an extensive literature review. The guideline deals with basic knowledge and methodological aspects of AIT, including mechanisms, clinical efficacy, patient selection, allergens extract selection, schedule and doses, management of adverse reactions, efficacy measurements, and special consideration in pediatrics. The guidelines for sublingual immunotherapy will be covered in detail in a separate article.

Feasibility Study of Synthetic Diffusion-Weighted MRI in Patients with Breast Cancer in Comparison with Conventional Diffusion-Weighted MRI

Choi Bo Hwa,Baek Hye Jin,Ha Ji Young,Ryu Kyeong Hwa,Moon Jin Il,Park Sung Eun,Bae Kyungsoo,Jeon Kyung Nyeo,Jung Eun Jung 대한영상의학회 2020 Korean Journal of Radiology Vol.21 No.9

Objective: To investigate the clinical feasibility of synthetic diffusion-weighted imaging (sDWI) at different b-values in patients with breast cancer by assessing the diagnostic image quality and the quantitative measurements compared with conventional diffusion-weighted imaging (cDWI). Materials and Methods: Fifty patients with breast cancer were assessed using cDWI at b-values of 800 and 1500 s/mm2 (cDWI800 and cDWI1500) and sDWI at b-values of 1000 and 1500 s/mm2 (sDWI1000 and sDWI1500). Qualitative analysis (normal glandular tissue suppression, overall image quality, and lesion conspicuity) was performed using a 4-point Likert-scale for all DWI sets and the cancer detection rate (CDR) was calculated. We also evaluated cancer-to-parenchyma contrast ratios for each DWI set in 45 patients with the lesion identified on any of the DWI sets. Statistical comparisons were performed using Friedman test, one-way analysis of variance, and Cochran’s Q test. Results: All parameters of qualitative analysis, cancer-to-parenchyma contrast ratios, and CDR increased with increasing b-values, regardless of the type of imaging (synthetic or conventional) (p < 0.001). Additionally, sDWI1500 provided better lesion conspicuity than cDWI1500 (3.52 ± 0.92 vs. 3.39 ± 0.90, p < 0.05). Although cDWI1500 showed better normal glandular tissue suppression and overall image quality than sDWI1500 (3.66 ± 0.78 and 3.73 ± 0.62 vs. 3.32 ± 0.90 and 3.35 ± 0.81, respectively; p < 0.05), there was no significant difference in their CDR (90.0%). Cancer-to-parenchyma contrast ratios were greater in sDWI1500 than in cDWI1500 (0.63 ± 0.17 vs. 0.55 ± 0.18, p < 0.001). Conclusion: sDWI1500 can be feasible for evaluating breast cancers in clinical practice. It provides higher tumor conspicuity, better cancer-to-parenchyma contrast ratio, and comparable CDR when compared with cDWI1500.

유방 자가 검진 참여 교육 프로그램이 유방 자가 검진 이행과 건강 증진 행위에 미치는 영향*

박은하(Park Eun Hwa),류은정(Ryu Eun Jung),최경숙(Choi Kyung Sook) 대한종양간호학회 2003 Asian Oncology Nursing Vol.3 No.2

This study is carrying out a before and after experiment design for the non-equal comparative group to identify the effects of the breast self-examination education on breast self-examination participant education compliance and health promotion in women. The subject of this study was 58 women residing in Chungju. Their age ranged from 20 to 40. These women were not pregnant or did not breast feed, as well as they did not have any breast disease, at the time of survey. They were available for the response to the questionnaires, and understood the purpose of this study. They also agreed to participate in the study, and responded to the 3rd time questionnaires to the end. Thus, brochures and lectures were provided side by side to a group of 19 of those women, and only<br/> brochures were provided to another group of 39 of those women.<br/> With regard to education, a brochure and a program using a breast model were applied. Then, the frequency of the breast self<br/> examination compliance, breast self examination capability and the relations between the breast self examination and activities to promote health were measured, before the education, after 4 weeks of education and after 12 weeks of education. Before education and after 4 weeks of education, I collected the questionnaires myself visiting them, and after 12 weeks of education, the questionnaires were collected by mail.<br/> In relation to the study tool, the breast self examination activity was measured by two measuring tools: breast self examination<br/> activity frequency and breast self examination compliance capability. As for the frequency, the number of self examination for the period of 3 months, before the questionnaire survey, was<br/> measured in the form of self report. In relation to the tool to measure the breast self examination capability, the BSEPRI tool, which was developed by Wood in 1994, was used. Here, as the score was higher, the capability was indicated to be higher. The anslated and revised version of Health Promoting Lifestyle Profile Ⅱ (Walker, Sechrist & Pender, 2002) was used as a tool for health promotion. As the measured score was higher, the health promoting activity was indicated to be higher.<br/> The results of this study were as follows;<br/> 1. As a result of checking the breast self examination compliance frequency between the experiment group that received the breast self examination participant education and the comparative group that did not receive the education, there was a significant difference in interaction between groups by time, as time passed by.<br/> 2. As a result of checking the breast self examination compliance capability between the experiment group and the comparative<br/> group, there was a significant difference in interaction between groups by time, as time passed by.<br/> 3. As a result of carrying out a repetitive measurement analysis, between the experiment group that received the breast self examination education and the comparative group that did not receive the education, which was carried out to validate<br/> the hypothesis that the former would have higher health promoting activities than the latter, there was no significant difference<br/> after the breast self examination education was conducted.

진동센서를 활용한 에어 드럼 교습 시스템의 설계 및 구현

박여은 ( Yeo-eun Park ),강용화 ( Yong-hwa Kang ),류정욱 ( Jeong-wook Ryu ),송은비 ( Eun-bi Song ),장병욱 ( Byeong-wook Jang ),김정민 ( Joung-min Kim ),박미화 ( Mee-hwa Park ) 한국정보처리학회 2017 한국정보처리학회 학술대회논문집 Vol.24 No.2

드럼은 현대인의 스트레스 해소와 노인 치매예방, 소아의 뇌 성장에 도움이 되는 반면, 악기의 크기가 크고 연습 시 발생하는 소음으로 인해 시간적, 공간적인 제약이 많은 악기이다. 본 논문에서는 드럼을 언제 어디서나 연습할 수 있도록 도와주는 에어 드럼 교습 시스템을 제안한다. 에어 드럼 교습 시스템은 진동센서가 부착된 드럼 스틱과 휴대폰용 어플리케이션만으로 드럼연주가 가능하다. 에어 드럼 교습 시스템은 드럼 스틱에 장착된 진동센서를 이용해 사용자의 드럼 연주 신호를 실시간으로 인지하고, 휴대폰에 설치된 모바일 어플리케이션에서 진동 신호를 드럼 연주 소리로 변환하여 출력한다. 또한 에어 드럼 교습 시스템은 사용자의 연주 패턴을 분석하여 드럼의 기본 패턴과의 박자, 음정, 세기에 대한 유사도 점수를 제시하여 사용자의 드럼 실력 향상에 도움을 준다. 이를 위해, 본 논문에서는 사용자가 연주하는 동안 진동 센서에서 인지한 신호를 하나의 박자로 구분하기 위한 제어 기술과 실시간 연주 및 유사도 점수를 제시하는 에어 드럼 교습 어플리케이션 ‘WeFlash’의 설계와 구현 결과를 제시한다.