단결정 Si(111) 위에 형성된 Ti-실리사이드에 대한 RBS 및 XRD 분석

이중환,권오준,최치규,박동수,김건호,이상환,이의완,곽호원 濟州大學校 基礎科學硏究所 1991 基礎科學硏究 Vol.4 No.1

초고진공 상태에서 p형 Si(111)기판에 Ti을 증착한 후 고진공에서 열처리하여 Ti-실리사이드를 형성시켰으며, Ti-실리사이드의 상전이 및 형성운동학은 2 MeV⁴He? 이온 후방산란과 x-선 회절방법으로 규명하였다. 형성된 TiSi₂는 결정학적으로 C49(ZrSi₂)와 C54 구조의 두 종류로 확인되었다. C49 TiSi₂상은 열처리온도가 700℃이하의 저온에서 형성되었고, 700℃ 이상의 고온에서는 C54 TiSi₂상으로 나타났다. 본 연구에서 확인된 C54 TiSi₂전이온도(??)는 700℃ 였고, TiSi₂형성온도 영역내에서 TiSi₂ 층두께(χ)와 열처리시간(t)의 관계는 저온(700℃ 이하)일 경우 ??이고, 고온(750℃ 이상)에서는 χ=ct+d 의 관계식이 만족됨을 알 수 있었다. 이것은 700℃ 이하에서 TiSi₂ 형성기구가 Si 확산에 의해 제어되며, 750℃ 이상에서는 핵형성 제어에 의하여 계면반응하는 것으로 나타났다. Titanium silicides were prepared by depositing titanium film on p-type Si(111) followed by annealing in ultra high vacuum. The growth kinetics of Ti-silicide has been studied by using ion backscattering spectrometry and x-ray diffractometry. Two crystallographic structures of Ti-silicide were identified the (ZrSi₂)structure and C54. The C49 TiSi₂ phase was formed at low annealing temperature(<700℃),and it transformed to the C54 phase over 700℃. The relation between the thickness of TiSi₂ layer(χ) and the annealing time(t) was ?? when annealing temperature was under 700℃ and χ=ct+d when that was over 750℃. The former implied that the formation of TiSi₂ was controlled by diffusion and the latter by nucleation of at the Ti/Si(111) interface.

實驗大學을 위한 敎養英語敎育의 改善方案 : 경북대학교를 중심으로

蔡俊基,朴英壽,李愚鍵,金漢昌 慶北大學校 語學硏究所 1977 語文硏究 Vol.2 No.-

2 CASES OF RABBIT SYNDROME : 토끼증후군 2례

민병근,이창화,안준호,천두욱,김헌수 울산대학교 의과대학 1994 울산의대학술지 Vol.3 No.2

The application of neuroleptics to schizophrenic and other psychotic patients in the early 1950's led to the therapeutic revolution into the psychiatry, on the other hand neuroleptic-related adverse effects did frequently occur. The authors experienced 2 cases of rabbit syndrome producing by rare complication of neuroleptic medication. Two cases were examined for the rabbit syndrome by the description of Villeneuve(1972) and Sovner and DiMascio(1977). The reciprocal coordination test and the finger-tapping technique to worsen the symptoms also were applied to two patients. The authors emphasized two issues of rabbit syndrome as follows. First, though the literature search showed that the majority of patients presented with rabbit syndrome which is usually seen after a prolonged exposure to neuroleptic medication with the more potency in the middle or elderly aged are over 45 years old, we suggest that this syndrome might be linked to the younger age factor and the low potency thioridazine in our patient. Second, the rabbit syndrome is in the importance of the clinical practice because of being readily reversible with antiparkinsonian agents or anticholinergic drugs. In addition, recognizing this condition and differentiating it from tardive dyskinesia helps in the choice of the proper treatment of orofacial disorders following neuroleptic medication for the long time.

정보제공자와의 면담에 의해 진단된 뇌졸중후치매의 유병률과 상관인자에 관한 연구

배희준,이건세,김형수,김병건,구자성,권오현,박종무 대한치매학회 2004 Dementia and Neurocognitive Disorders Vol.3 No.2

Background and Objectives: With increasing age of population, stroke and dementia become greater health problems in Korea. However, there have been no studies on poststroke dementia in Korea. We intended to elucidate the frequency and clinical correlates of poststroke dementia in a hospital-based cohort. Methods: From July 2001 to July 2002, 372 patients were hospitalized to Eulji General Hospital within 7 days from onset with acute stroke or transient ischemic attack. Two hundred-eight patients (55.9%) were followed up and interviewed more than 1 year later (451 ±83.3 days). Dementia was diagnosed by Korean Dementia Screening Questionnaire (KDSQ) obtained by a direct interview. Based on Eulji Stroke Registry, demographic factors, risk factors for stroke, stroke characteristics, and stroke outcomes were gathered and examined. Results: Of 208 patients, poststroke dementia was detected in 36 patients (17.3%, 20 males, age=64.5±9.4 years). Poststroke dementia was associated with history of stroke, aphasia, modified Rankin Disability Scale (MRDS) at 3 month after stroke and when interviewed, and Barthel index at 6 months after stroke (p;0.05). Its correlation with diabetes mellitus and National Institute of Health Stroke Scale at discharge were marginally significant (0.05;p;0.1). Conclusions: Post-stroke dementia is common in Korean stroke patients. Its frequency is comparable to that in other countries. The correlates of poststroke dementia and their clinical meanings are demonstrated.

운동성 산화 스트레스와 항산화비타민의 보충이 말초단핵세포의 NF-kB 활성에 미치는 영향

진영수,박건구,박준영,김미정,이왕록,김혜영,이한준,박은경 대한스포츠의학회 2000 대한스포츠의학회지 Vol.18 No.2

Reactive oxygen species(ROS) are implicated in the pathogenesis of a wide variety of human diseases. Numerous studies indicate that ROS may serve as common intracellular molecules that contribute to the process of nuclear factor(NF)κB activation in response to a diverse stimuli. In our laboratory, we have demonstrated tat antioxidants could reverse the decline of immune function caused by exercise-induced ROS. Furthermore, it in necessary to understand a mechanism underlying ROS-dependent disorder in biological system. Recent studies have been shown that several gene expression were regulated by oxidants, antioxidants and other determinants of the intracellular reduction-oxidation(redox) state. In this process, NF-κB have been shown to play a important role. The purpose of the present investigation was to evaluate the effect of exercise-induced oxidative stress and antioxidnt supplementation on NF-κB activation in peripheral mononuclear cells. Forty male SD rats(4 weeks old) were randomly divided into noraml diet group and antioxidants(ATO) supplement group, and then ATO groups were treated with antioxidants(VE: 2001U/kg, VC: 50mg/rat, β-carotene: 300mg/kg, vitamin B6: 250㎍/100g, selenomethionine: 0.1mg/kg) for 16 weeks. After 16 weeks breeding at each condition, each group divided into two groups: Control group(CR) fed generally, Exercise group(CE) fed generally and followed by acute exercise 16 weeks later. Antioxidant Antioxidants and Exercise group(AE) fed with antioxidants and followed by acute exercise. The activation of NF-κB binding activity was increased after exhaustive exercise bout in both group. In addition, pretreatment of ATO group with the antioxidants mixture lead to the inhibition of NF-κB binding activity. This results suggest that NF-κB activation should be further studies in response to a variety of exercise.

작은 피질하 병변에 대한 정위적 개두술 및 경-구 접근법

손병철,김문찬,이관성,박춘근,홍용길,강준기 대한신경외과학회 1999 Journal of Korean neurosurgical society Vol.28 No.12

충주시 농촌지역 주민들에 대한 보건교육 평가

권복규,양준호,송진범,이건세,이원진,장성훈 건국대학교 의과학연구소 1996 건국의과학학술지 Vol.5 No.-

The aim of this study was to evaluate the effect of health education program in Choongju rural area which had conducted by Public Health Doctor during winter in 1994 and 1995. We used two step sampling method for a household survey. First, six were selected from 12 Myuns, which were stratified by the level of health education activity. Second, we applied convenient sample method. Of the 307 respondents, most of them knew Health-subcenter's existence in their region. However, only 149 persons(45%) visited it during last year. They visited Health-subcenter because it was easy to travel and convenient. Some of them thought that Health-subcenter had very poorly equipped and supplied. About 32∼34% of respondents participated the health education program for hypertension and diabetes mellitus which was done last winter, and 59∼70% of participants of the program answered that it was very, moderately helpful. 82∼83% of participants recognized complications of hypertension and diabetes mellitus, and 18∼20% of them did not know that medications of hypertension and diabetes mellitus should be continued one's whole life. The respondents want to receive health educations for cancer, arthritis, viral hepatitis and AIDS in orders. Many of rural residents utilize Health-subcenters because health clinics in Choongju rural area are very few.

당뇨병환자에서 뇨증 Fibronectin농도의 증가에 관한 연구

한승범,조준승,손건영,서성문,박근용,조성래,박규영,박정모,이인규,여준기 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4

Plasma fibronectin is an α₂-glyoprotein, which is produced by vascular endothelial cells. Raised level of plasma fibronectin has been observed in diabetic patients particularly in the presence of microvascular complications. However, no available data exist about urine level of this glycoprotein in diabetic patients. We measured urine fibronectin level by ELISA methods in 54 diabetic patients who have microvascular comlications or not. The following results were obtained. 1) Urine fibronectin level(㎍/g creatinine) in diabetic group(1740.0±678.0) is increased compaired with those in normal control group(471.0±59.0). but this results were not significantly different among two groups(P>0.05). 2) Urine fibronectin level(㎍/g creatinine) was significantly increased in patients with nephropathy (6188.0±3144.0) compared with those in normal control group(471.0±59.0) and patients without nephropathy(645.0±251.0)(P<0.001). 3) There were a significant correlation between BUN, creatinine, creatinine clearance, 24hr urine total protein and urine fibronectin level in diabetic patients. Our data suggest that urine fibronectin excretion level might be used as a sensitive guide for diabectic nephropathy.

Real Time Measurement of Protease Activity of Live Uronema marinum (Ciliata:Scuticociliatida) by Fluorescence Polarization Assay

Lee, Kun Hye,Kwon, Se Ryun,Kim, Chun Soo,Chung, Joon Ki,Lee, Hyung Ho,Kim, Ki Hong 한국수산학회 2002 Fisheries and Aquatic Sciences Vol.5 No.4

Proteolytic activity of live Uronema marium was analyzed by fluorescence polarization (FP) technique. Protease activity was measured by a decrease in FP value using fluorescein isothiocynate (FITC)-casein as a protein substrate. The results demonstrated an inverse linear relationship between fluorescence polarization (FP) values and live ciliate concentration over the range 1×10^4 to 2×10^5 cells/well. However, the FP values of 10~10^3 live parasites were not different significantly from that of control. Time-dependent decrease in FP value was shown in the wells containing live U. marinum. In the present study, FP assay had the benefit to provide measurements of substrate hydrolysis by live parasites in real-time, and did not require separations, precipitations, or transfers of reaction mixture.

Theoretical Investigation of CO2 Adsorption on Graphene

Kun-Joon Lee,김승준 대한화학회 2013 Bulletin of the Korean Chemical Society Vol.34 No.10

The adsorption of carbon dioxide on graphene sheets was theoretically investigated using density functional theory (DFT) and MP2 calculations. Geometric parameters and adsorption energies were computed at various levels of theory. The CO2 chemisorption energies on graphene-C40 assuming high pressure are predicted to be 71.2-72.1 kcal/mol for the lactone systems depending on various C-O orientations at the UCAM-B3LYP level of theory. Physisorption energies of CO2 on graphene were predicted to be 2.1 and 3.3 kcal/mol, respectively, at the single-point UMP2/6-31G** level of theory for perpendicular and parallel orientations.