전도성 고분자 센서 어레이를 이용한 휘발성 유기 화합물 가스 인식

이경문,주병수,유준부,황하룡,이병수,이덕동,변형기,허증수 한국센서학회 2002 센서학회지 Vol.11 No.5

휘발성 유기 화합물 가스(Volatile Organic Compounds)를 인식하고 분석하기 위하여 전도성 고분자 센서어레이를 이용한 시스템을 제작하였다. Polypyrrole와 Polyaniline을 화학중합법으로 센서에 전도성고분자막을 형성하였고 이를 통해 VOC 검지용 센서 어레이를 제작하였다. 센서어레이로부터 측정되는 다차원 데이터는 주성분분석법(PCA)과 RBF(Radial Basis Function Network)을 이용하였다. 제안된 시스템으로 VOCs 가스를 인식하는데 있어서 RBF Network이 PCA방식보다 더욱 효율적인 것으로 판단되었다. We fabricated gas recognition system using conducting polymer sensor array for recognizing and analyzing VOCs(Volatile Organic Compounds) gases. The polypyrrole and polyaniline thin film sensors which were made by chemical polymerization were employed to detect VOCs. The multi-dimensional sensor signals obtained from the sensor array were analyzed using PCA(principal component analysis) technique and RBF(radial basis function) Network. Throughout the experimental trails, we confirmed that RBF Network is effective than PCA technique in identifying VOCs.

비만세포주에서 Histamine 유리에 관한 연구

김형룡,국윤아,신민,이홍수,원진숙,김형민,이영미,정헌택,이혜숙,안녕형 원광대학교 생명공학연구소 1995 생명공학연구소보 Vol.3 No.1

요골동맥을 이용한 관동맥 조영술의 유용성

윤정한,이승환,이한요,김장영,김일회,최윤종,이형준,이명옥,김승년,황성오,홍인수,최경훈 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.10

추황배(Pyrus pyrifolia Nakai cv. Chuhwangbae) 과피로부터 1종의 Sterol과 3종의 배당체 화합물의 단리·동정

이유건(Yu Geon Lee1),조정용(Jeong-Yong Cho),이현주(Hyun Joo Lee),이용현(Yong Hyun Lee),이상현(Sang-Hyun Lee),한태호(Tae-Ho Han),김월수(Wol-Soo Kim),박근형(Keun-Hyung Park),문제학(Jae-Hak Moon) 한국식품과학회 2013 한국식품과학회지 Vol.45 No.5

본 연구에서는 배의 유용성 증명을 위한 일환으로 배의 화학성분을 분자수준에서 밝히고자 하였다. 이에 배 과피 MeOH 추출물을 용매분획하여 얻은 EtOAc-산성 분획과 EtOAc-중성분획을 대상으로 Sephadex LH-20, silica gel, 그리고 ODS colmn chromatography와 HPLC를 이용하여 정제 및 단리하였다. 그 결과, EtOAc-산성 분획과 EtOAc-중성 분획으로부터 각각 2종씩의 화합물을 단리하였다. 단리된 화합물 1-4는 1H- 및 13C-NMR 분석을 통하여 각각 (S)-(+)-2-cis-abscisic acid O-β-D-glucopyranosyl ester (화합물 1), 1-[4-O-β-D-glucopyranosyl]phenyl ethanone(piceoside, 화합물 2), β-sitosterol (화합물 3), 그리고 β-sitosteryl 3-O-β-D-glucopyranoside (화합물 4)로 동정되었다. 단리된 3종의 배당체 화합물(화합물 1, 2, 4)들은 본 연구에 의해 배로부터 처음 동정되었으며, 화합물 3은 추황배로부터 처음 동정되었다. 본 연구결과가 배 함유 성분연구는 물론 배의 기능성 해명 연구에도 추후 중요한 기초자료로 활용되길 기대한다. We isolated and identified antioxidants from acidic and neutral ethyl acetate fractions of the peel of pear (Pyrus pyrifolia N. cv. Chuhwangbae). We isolated 4 compounds from the methanol extract, by using 3 different types of column chromatography (Sephadex LH-20, silica gel, and octadecylsilane) and preparative HPLC. We identified the isolated compounds as (S)-(+)-2-cis-abscisic acid O-β-D-glucopyranosyl ester (compound 1), 1-[4-O-β-D-glucopyranosyl]phenyl ethanone (picroside, compound 2), β-sitosterol (compound 3), and β-sitosteryl 3-O-β-D-glucopyranoside (compound 4) by nuclear magnetic resonance analysis. We are the first to report the identification of compounds 1, 2, and 4 from pear.

림프종 환자에서의 갈륨, TI-201 그리고 Tc-99m MIBI 섭취의 비교

천경아,조인호,원규장,이경희,이형우,현명수,이재태,이규보 영남대학교 의과대학 2002 Yeungnam University Journal of Medicine Vol.19 No.2

Purpose; Ga-67 scintigraphy has been used for the evaluation of tumors, especially lymphoma. Recently, Tl-201 and Tc-99m MIBI were also used to tumor imaging. Tl-201 and Tc-99m MIBI had better physiologic characteristics than Ga-67, so we studied 32 biopsy proven lymphoma patients (male 24, female 8, mean age 46 years) with Ga-67, Tl-201 or Tc-99m MIBI and compared the scan findings. Materials and Methods: Twenty-three of 32 patients were injected 74-111 MBq (2-3 mCi) of Tl-201, before chemotherapy and imaged with dual-headed SPECT (Prism 2000, Picker, USA) at 30 minutes after injection. Delayed images were obtained after 3 hr in 8 patients. Twenty seven of 32 patients were injected 740 MBq (20 mCi) of Tc-99m MIBI and imaged at 30 minutes after injection. 111-185 MBq (3-5 mCi) of Ga-67 was injected in 12 patients and imaged at 48 and 72 hours after injection. Twenty eight patients were diagnosed as non-Hodgkin's lymphoma and others were Hodgkin's lymphoma. Results: Twenty patients were positive on Tl-201 scan and 3 patients showed negative findings. One of these 3 patients, Tc-99m MIBI and Ga-67 scan were positive. Twenty two patients were positive on Tc-99m MIBI scan and 5 patients showed negative findings. One of these 5 patients, Tl-201 was positive and 2 were positive on Ga-67 scan. Ten of 12 patients showed positive findings on Ga-67 scan. The sensitivity of these agents were 83.3%, 87.0% and 81.5% for Ga-67, Tl-201 and Tc-99m MIBI, respectively. The sensitivity was highest in Tl-201 scan, but there were no significant differences among three tests. In this study, there was no significant difference of uptake ratios between early and delayed images of Tl-201. Conclusion: Scintigraphy with Tl-201 and Tc-99m MIBI in lymphoma patients have similar sensitivity with Ga-67.

각국의 경찰부패통제제도에 관한 비교 연구

이황우,남형수 동국대학교 사회과학연구원 2008 사회과학연구 Vol.15 No.1

Although the South Korean government has for a long time exerted to prevent and control corruption of public officials, it seems still pervasive in South Korea. The corruption scandals of the police are also considered a part of this social problem. For example, the extent of police corruption cases has been reduced since the National Police Agency in South Korea vigorously implemented anti-corruption policies and attempted to clean its organization. However, it is seemed that police corruption still remains in the particular divisions in a police department, such as investigation bureau, order maintenance team, and so forth, in which the officers frequently make contacts with citizens in a daily manner. For citizens, police corruption is perceived as a barometer of corruption of public officials since the police department is a frontline entity of law enforcement agencies. Police corruption undermines police accountability and legitimacy of law and authority. In order to enhance citizens' confidence of the police, it is inevitable to establish effective policies and measures to prevent police corruption. This study, by comparing diverse anti-corruption policies of the police across countries, aims to suggest a new systemic control model of police corruption 1) enhancing the education of police ethics, 2) improving police culture, 3) encouraging self-cleaning activities by a practical evaluation, 4) considering the settlement of systemic innovation, 5) establishing an anti-corruption system, and 6) encouraging citizen participation. 정부에서는 그동안 공직부패 척결을 위하여 범정부차원에서 다양한 정책적 노력을 기울여 왔으나 여전히 부패가 만연한 나라라는 오명을 벗지 못하고 있다. 경찰도 예외는 아니라서 강력한 부패근절방안과 조직 차원의 지속적인 자정노력으로 경찰부패가 많이 사라졌지만, 아직까지도 사건수사와 풍속업무분야 등 대민접점부서에서의 비리는 완전히 근절되지 않고 있다는 평가를 받고 있다. 경찰은 최일선의 법집행기관으로서 경찰부패는 국민이 피부로 느낄 수 있는 공직사회 부패의 바로미터로 인식되고 있다. 이러한 경찰부패는 법집행력의 약화를 초래하게 되고, 법을 집행하는 경찰이 법을 어기거나 제대로 집행하지 않는 다면 법과 권위를 스스로 깨뜨리는 행위가 된다. 따라서 국민으로부터 신뢰받는 경찰이 되기 위해서는 경찰의 부패방지대책을 수립하는 것이 급선무라고 생각한다. 이에 이 연구에서는 각국의 경찰부패통제제도를 비교 분석하여 보다 근본적이고 새로운 경찰부패통제시스템의 도입방안으로 경찰관의 윤리교육 강화, 조직문화의 개선, 실질적 평가를 통한 자율적인 부패방지 노력, 제도적 개선사항의 정착화 방안의 강구, 조직의 반부패시스템 구축, 시민참여제도의 강화 등을 제시해 보았다.

외측상과염에 관한 고찰

이문환,신형수 대한정형도수치료학회 2005 대한정형도수물리치료학회지 Vol.11 No.2

Lateral epicondylitis is characterized by pain at the lateral aspect of the elbow, commonly associated with resisted wrist or finger extension and gripping activities. Lateral epicondylitis is also known such as lateral epicondylosis, tennis elbow, or tendonitis of the wrist extensor muscles, especially extensor carpi radialis brevis. Lateral epicondylitis is a common musculoskeletal lesion in the clinical states, so physical therapist usually meet a patients who has the lateral epicondylitis. But many of physical therapists are treating patients based on a self know-how, so I want to describe a systematically about lateral epicondylitis and give a objective information on the lateral epicondylitis. And now I want that they will be treat patients with lateral epicondylitis not a self-experience but based on a objective information.

의복구성학의 연구주제 및 경향분석

이정순,나수임,배주형 복식문화학회 2001 服飾文化硏究 Vol.9 No.2

The purpose of this study is to recognize the real situation of clothing construction to present the desirable direction to establish more scientific and reasonable themes of the study by analysis of the tendency of the clothing construction study. For this purpose, 402 papers on the theme of clothing construction study were excerpted from the first issues to the issues of December in 1999 of Journal of Korea Society of Clothing and Textile, Journal of Korea Home Economics, Journal of the Korean Society of Costume, Research Journal of the Costume Culture, Journal of the Korean Fiber Society, and Journal of the Human Engineering Society of Korea, I analyzed and classified the theme into eight issues of design related clothing construction, study of body types, study of patterns, size of apparel, fitting of clothing, protective clothing and functional clothing, sewing, and the others. The result of the study is as follows. 1. The distribution tendency of the clothing construction study by the journal of each society showed that Journal of Korean Home Economics is 22.9%, Journal of Korea Society of Clothing and Textiles 17.3%, Research Journal of the Costume Culture 12.2%, and Journal of the Korean Society of Costume 6.2%. 2. The distribution tendency of the studying issues showed that study of body types is 29.4%, study of patterns 21.9%, fitting of clothing 11.7%, sewing 10.2%, size of apparel 8.5%, and others 7%, protective clothing and functional clothing 6.7%, and design related clothing construction 4.7%. Considering the above result, we can understand that study of body types and patterns are being studied most actively. 3. Regarding the study tendency by academic issues showed that study of construction elements and design application is chiefly centered of the study of design related clothing construction (35.5%), analysis of body types is centered of the study of body types (46.6%), CAD is centered of the study of patterns (31.1%), and size spec for the ready made patterns is centered of the study of size of apparel (32.4%). As for fitting of clothing, the study was performed in two ways on the changes of the surfaces of human bodies in motion and the functional features of experimental dressing. Regarding the study of sewing, study of fusible interlining was mainly performed (36.6%) and regarding the study of protective clothing and functional clothing, study of brassieres and underwear was chiefly performed. Key words : design related clothing construction(디자인관련 의복구성), study of patterns(의복 및 패턴 연구), size of apparel(의류치수), fitting of clothing(의복의 맞음새), protective clothing and functional clothing(특수복 및 기능복).

Polymer Light Emitting Diode의 발광특성 연구 : A study on electoluminescence properties of PLED with poly [2-(2'-ethylhexyloxy)-5-methoxy-1,4-phenylenevinylene]

이상협;배형철;송석태;한찬수;채희백 순천향대학교 기초과학연구소 2010 순천향자연과학연구 논문집 Vol.16 No.2

In order to know how the [2-(2'-ethylhexyloxy)-5-methoxy-1,4-phenylenevinylene] (MEH-PPV) layer works in organic light emitting diode, two different types of devices were fabricated, which are MEH-PPV single layer devices and MEH-PPV/tris (8-hydroxy-quinoline)aluminium(Alq3) bilayer devices. On the indium-tin-oxide(ITO) glass anode MEH-PPV layer was first spin-coated, and the Alq3 layer and the aluminium(Al) anode were vapor-deposited sequentially. The devices shows a trend that has lower current, luminous efficiency in case the thickness of the device is larger. Some bilayer devices, however, show more improved performance than other devices of smaller total thickness. This results were discussed on the basis of improved exciton formation resulting from balanced carrier transport.

어류에 발생하는 Mycobacterium 속 세균성 질병에 대하여

이덕찬,김도형,박수일 한국어병학회 2001 한국어병학회지 Vol.14 No.3

Mycobacterium 속 균은 일반적으로 Gram 양성 및 음성균의 세포벽에서 관찰되는 구조 및 성분과 차이가 나며, 장시간 동안 배양해야 하는 등의 특성이 있다. Mycobacterium속 세균의 세포벽에는 다량의 mycolic acid가 함유되어 일반 염색법으로느 염색이 잘되지 않으나 일단 염색되면 산이나 알칼리에 탈색되지 않는 성질을 가지고 있으므로 항산성균이다. 그람 양성 간균, 비운동성, 호기성이며 아포는 없고 발육이 느리다. 그러므로 이러한 균의 배양, 분리 그리고 동정에는 Gram 양성 및 음성균에서 수행하는 일반적인 생화학 및 생리학적 방법 외의 다양한 시험들이 필요하다. Atexander(1913)에 의하여 'piscine tuberculosis'로 보고된 후 어류에 피해를 주는 여러 종류의 Mycobacterium 속의 세균군이 보고되었다. 최근까지 해수어와 담수어 40과 151종 이상의 어류에서 감영 가능성이 보고되어 있으며 특히, 열대성 담수어와 해수어, 온대성 담수어류 및 관상어류 등에서 주로 보고되었다. 어류에 감염을 일으키는 균으로는 M. marinum, M. chelonae 및 M. fortuitum이 잘 알려져 있으나, 최근 어류뿐만 아니라 양서류, 파충류 및 갑각류 등에서 M. simiae, M. scrofulaceum, M. poriferae, M. kansasii 및 M. peregrinum 등과 미국의 Chesapeake 만의 자연산 sea bass에서 Mycobacterium chesapeake sp. nov.이 보고되었다. 어류의 mycobacteriosis는 오염된 먹이나 수중 부유물질에 부착된 병원체의 어체 상처 접촉에 의하여 수평적으로 확산될 수 있다. 감염된 어류는 먹이 섭취 불량, 운동성 저하, 복수 저류로 인한 복부팽만 등의 외부증상과 신장, 비장 및 간 등의 육아종 형성 등 전신적, 만성적 그리고 진행성 병변을 보인다. 어류에 질병을 일으키는 Mycobacterium sp는 65kDa과 <14kDa의 분자량을 가진 ECP를 생산하며, 세균 종에 따라 mucinase, lipase 또는 RNase를 생성한다. M. marinum에 의하여 생성된 ECP에 의한 독작용은 Vibrio anguillarum이나 Aeromonas hydrophila ECP에 비하여 약하며, 무지개송어와 나일틸라피아에 대한 LD_50은 400μg fish^-이다. 이들 병원균에 의한 감염증 발생 후 항생제를 사용하면 어류의 폐사는 줄어들지만 완전한 치료는 어려우므로 예방 조치가 필요할 것이다. 그리고 어류에 감염을 일으키는 Mycobacterium sp.에 의한 인체감염이 전세계적으로 보고되 있으며, 국내에서도 환경이나 사람의 객담(喀痰, sputum)으로부터 M. marinum과 M. fortuitum complex가 분리 보고되고 있으므로 앞으로 어류로부터의 감염에 대한 많은 연구가 필요하다. Bacteria of the genus Mycobacterium ard generally rod-shape, gram-positive, nonspore-forming, non-motile and acie-fast. They are quite different from the structures and compounds in common bacteria. The bacteria are not decolorized with acid-alcohol because of the cell walls composed of mush mycolic acis. The bacteria are relatively fastidious, growing very slowly on only a few special media. Therefore many kinds of experimental methods should be needed to isolate and identify mycobacteris besides physiological and biochemical methods commonly used. Serveral bacteria of the genue Mycobacterium have been reported after Alexander(1913)described piscine tuberculosis to refer to fish mycobacteriosis. Probablility of infection from 40 families, 151 species of fich to human hsd been reported until recent year, particularly including tropical freshwater and marine fishes, temperate frashwater fishes and aquarium fishes. The causative agents of the fish mycobacteriosis involve M. marinum, M. chelonae and M. fortuitum. Currently M. simiae. M. scrofulaceum, M. poriferae, M. kansasii and M. peregrinum have aldo been found in amphibians, reptiles and crustaceans and M. cheapeaki sp. nov. was isolated from wild sea bass in the gulf of Chesapeake, the US. The most probable route of transmission for fish mycobacteriosis is oral or through injuries of the skin which can be exacerbated by external parasites. Mycobacteriosis is a chronic progressive disease, with various clinical signs, including lack of movement coordination, abdominal swelling, inappetence, emaciation and inflammation of the skin. Interally greyish white nodules develop on various organs, particularly the liver, kidney and spleen. ECP from virulent Mycobacterium sp. has two different proteins, a 65 kDa and <14 kDa, and the ECP may contain mucinase, lipase or RNase depending on the kinds of bacteria. The ECP of M. marinum, with the LD_50 dose equated to 400㎍ fish^-1 for rainbow trout and Nile tilapia, is more toxie than those of Vibrio anguillarum and Aeromonas hydrophila. Prevention of the disease is perhaps the single most economical means to combat mycobacteriosis, since infected fish cannot be completely cured althouth the mortality may be reduced by application of antibiotics. It may be difficult to ruld out the possibility of human infection by Mycobacterium sp. which is virulent to fish, as the related reports have been described worldwide and also reported domestically on isolation of M. marinuma and M. fortuitum complex from the environment and sputum.