정신분열병 환자에서 병식, 기능, 증상에 대한 연구

이귀행,최성호,홍정완,이지혜,전현태 圓光大學校 醫科學硏究所 2006 圓光醫科學 Vol.21 No.2

Refractory Ceramic Fiber와 Rock Wool로 자극한 폐포대식 세포에서 Reactive Oxygen Species 분비와 관련된 세포내 신호변환계

이권행,임영,양경숙,오현숙,김은경,김경아 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.4

Objectives : It is known that the high fibrogenecity of particles is connected with their cytotoxicity for macrophages. Although the molecular mechanism leading to fiber-induced fiber-induced cytotoxicity is still not clear, several mechanism have been suggested. The release of reactive oxygen species(ROS) from activated alveolar macrophages(AM) by dust have been suggested as a possible mechanism of particle-induced cell damage. But the mechanism which man-made vitreous fiber(MMVF) induces the production of ROS in AM is still not clear. In this study, we evaluated the relationship between ROS production and lactate dehydrogenase(LDH) release from alveolar treated with refractory ceramic fiber(RF2) or rock wool(RWI) and signal transduction path-way of ROS production in RF2 or RW1 exposed AM. Methods : We investigated LDH release from MMVF-stimulated AM for index of cytotoxicity. To determine what kind of signal transduction pathways are involved in MMVF-stimulated ROS generation, we used some drugs which have an effect on the signal transduction pathway. Results : RF2 and RW1 induced increase of LDH release with dose-dependent manner with RF2 having greater effect than RW1. There was a dose-dependent increase in the production of ROS by RF2 or RW1. At all level of concentration, RF2 induced more ROS production than RW1. Inhibitors of PKC(bisindolylmaleimide), PLC(U73122 and neomycine) and PTK(genistein and erbstatin) suppressed RF2 or RW1-induced ROS production. Conclusion : There was significant correlation between LDH release and ROS production from AM treated with RF2 or RW1. RF2 and RW1 induced ROS generation through protein kinase C(PKC), phospholipase C(PLC) and protein tyrosin kinase(PTK) pathways.

精密測定 計器用 Stainless Steel의 加工과 熱處理에 따른 諸性質의 變化

李宗炫,安辛根,金學信 全北大學校 1988 論文集 Vol.30 No.-

In order to study the change of properties in Fe-13.3% Cr-0.37%C martensitic stainless steel for precision measuring gauge with the various heat treatments and plastic working, the change of micostructure, hardness and wear resistance were investigated. The results obtained in this experiment are as follows: 1. The high Cr alloy of 13% Cr martensitic stainless steel has selfhardening property which is not remarkably affected by the cooling rate, and also the hardness of this alloy was the highest value in the case of oil quenching after austenitized at 1000℃ for 1/3 hour. 2. The hardness and the corrosion resistance of low temperature tempering treatment are superior to high temperature tempering, especially the hardness of 200℃×2hr tempering treatment are superior to high temperature tempering, especially the hardness of 200℃×2hr tempering treatment in the case of air cooling after austenitized at 1050℃ for 1/3 hour is excellent. 3. The amount of retained austenite hardly existed in the case of air cooling after austenitized at 1000℃ for 1/3 hour, and the increase of hardeness with subzero-treatment is very small. 4. The property of hot working is good but the property of cold working is poor. And then, the secondary hardening with reheating treatment appeared at 400~450℃. 5. Bainite trasformation was occurred in the isothermal heat treatment, and the hardness and the wear resistnace of marquenching treatment are higher than martempering treatment. 6. The elevation of the wear resistance is proportional to the increase of the hardness obtained from the various heat treatments, especially the wear resistance of 200℃×2hr tempering treatment after air cooling is effective than after oil quenching and the wear mechanism is mainly a grinding abrasion.

일부 고지혈증 폐경 여성의 Isoflavone 공급에 따른 혈중지질 변화에 관한 연구

이다홍,승정자,이행신,김미현,서유리 대한지역사회영양학회 2001 대한지역사회영양학회지 Vol.6 No.1

Intake of soy protein may decrease the risk factors associated with cardiovascular disease in postmenopausal women. This study was designed to investigate the effects of isoflavone supplementation on serum lipids in 16 hyperlipidemic postmenopausal women. For this purpose, an intervention study was conducted for 12 weeks. Subjects were healthy, free-living women consuming habitual diets with 0.3 g/d of isoflavone. Food and nutrient intake was obtained by 24-hr recall method and anthropometric measurements were made. Systolic and diastolic blood pressure, total serum cholesterol, HDL-cholesterol and LDL-cholesterol were determined before and after the isoflavone supplementation. The results were summarized as follows. The average age, height, weight and BMI of the subjects were 65.3 years, 151.4 cm, 62.2 kg and 27.1, respectively. The systolic blood pressure and diastolic blood pressure were not reduced significantly with isoflavone supplementation. Total cholesterol (p < 0.001), HDL-C (p < 0.05), and LDL-C (p < 0.01) were significantly increased after isoflavone concentration. In conclusion, isoflavone supplementation was not effective to modify risk factors for cardiovascular disease.

미나리의 성분 특성

이형재,김용두,정현숙 順天大學校 師範大學 附屬 科學敎育硏究所 1994 科學과 敎育 Vol.2 No.-

미나리는 독특한 풍미 및 색깔을 지니고 질감과 영양이 뛰어나서 그 이용이 증가되고 있으나, 아직 연구가 미흡한 점을 주시하여 보다 나은 미나리의 활용을 위한 과학적 기초 자료를 얻고자, 미나리의 성분 특성 및 열처리와 냉각방법을 달리하여 ascorbic acid와 시각적 기호도에 영향을 미치는 chlorophyll의 변화를 검토하였는데 그 결과를 요약하면 다음과 같다. 무기성분은 칼륨과 칼슘의 함량이 높았고 줄기보다 잎에서의 함량이 높아 약 1.0-3.4 배의 차이를 나타냈다. 총 아미노산 함량은 줄기와 잎에서 각각 2139.50mg%, 3031.27mg% 였으며 잎의 함량이 줄기보다 1.42배 높았고 총 아미노산에 대한 필수 아미노산의 비율은 줄기가 37.14%, 잎이 37.71%로 나타났다. 확인된 아미노산은 16종이었으며 각 아미노산의 함량은 줄기에서 aspartic acid와 arginine이 주요 구성 아미노산으로 전체의 22.08%를 차지하였고 lysine > histidine > glutamic acid 순으로 함량이 많았으며 잎의 경우는 glutamic acid, arginine이 주요 구성 아미노산으로 18.93%를 나타냈고, aspartic acid > leucine> lysine의 순으로 함유되었으며, 이는 줄기의 주요 아미노산의 함량과 차이를 나타냈다. 줄기와 잎에서 ascorbic acid 함량은 각각 7.60mg%, 8.72mg%였으며 cholrophyll의 함량은 각각 16.33mg/g, 34.83mg/g로 잎부위가 줄기부위보다 높았다. 열처리 방법에 따라서 ascorbic acid 보유율은 microwave 열처리에서 가장 높았고 1000㎖식염수(1%) > 1000㎖ >500㎖ 순이었으며, chlorophyll 보유율은 1000㎖ 식염수 (1%) >microwave > 1000㎖ > 500㎖ 순으로 높았다. 냉각 방법에서도 실온 방치 냉각보다 냉수 냉각이 훨씬 더 높은 ascorbic acid, chlorophyll 보유율을 보였다. The use of the waterdropwort(Oenanthe javanica DC) as both health food and taste food tends to increase, while the researches on it have not been sufficiently made. For the purpose of obtaining the scientific, basic data for the better use of the water dropwort, the present thesis deals with the researches on the changes in the water dropwort : the ascorbic acid and chlorophyll change depending upon the varied heating and cooling methods which influence visual taste. The research results are as follows. The water dropwort contained greater amount of minerals such as K and Ca, and the leaf had 1.0-3.4 times as much content as the stem. The total amino acid content was 2139.50 mg% in the leaf -1.42 times more in the leaf than in the stem. The ratio of essential amino acid to the total amino acid was 37.14% in the stem and 37.71% in the leaf. 16 different kinds of amino acid were detected from the water dropwort. Aspartic acid and arginine were the major amino in the stem, representing 22.08% of the total, and the content was in the order of lysine, histidine, glutamic acid. Glutamic acid and arginine were the major amino acid in the leaf, representing 18.93% of the total, and the content was in the order of aspartic acid, leucine, lysine. The content of ascorbic acid was 7.60 mg% in the stem and 8.72 mg% in the leaf. The content of chlorophyll was 16.33 mg/g in the stem and 34.83 mg/g in the leaf. When the water dropwort was heated, the retention rate of ascorbic acid was the highest in the case of microwave heating method, and the rate was high in the order of 1000㎖(1% NaCl)>1000㎖>500㎖. The retention rate of chlorophyll was high in the order of 1000㎖(1%NaCl)>microwave>1000㎖>500㎖. When the water dropwort was cooled, the retention rate of ascorbic acid and chlorophyll was higher in the cool water cooling than in the room temperature cooling.

졸-겔법에 의한 PbTiO₃박막의 전기적 특성

김행구,이종헌 東亞大學校 附設 情報通信硏究所 1997 情報通信硏究所論文誌 Vol.5 No.1

The PbTiO₃thin films have been deposited by sol-gel processing on Si-wafer and ITO glass substrates. The creak-free films have been obtained after rapid thermal annealing at 700℃ for 10minute and characterized by XRD,SEM and electrical measurements. Their tetragonality c/a was 1.048 and grain size was 0.25㎛. When the structure of specimen was Au/PbTiO₃/ITO(MEN) and thickness of thin films with 10 coating was 0.8㎛, dielectric constant, dielectric loss and Curie temperature were about 114, 0.04 and 505℃ at 10㎑, respectively. Spontaneous polarization Ps, remnant polarization Pr and coercive field Ec were calculated by hysteresis loop and their values were about 2.72μC/㎠, 0.72μC/㎠ and 79㎸/㎝.

소년원생들의 체육활동 만족도에 관한 연구

박현조,이상행 圓光大學校附設 生活體育硏究所 1994 生活體育硏究 Vol.5 No.-

The purpose of this study are to investigate and analyze the 214 inmate juvenile of Chon-ju city to see sports and exercise activity and flow experience by the questionnaire. The major findings obtained by this study were as follows: 1. The inmate juvenile is content with sports and exercise activity. 2. The sports and exercise activity of the inmate juvenile increase the degree of a flow experience. 3. The contentment of inmate juvenile's sports and exercise activity has no difference in the type of each crime or his own school career. 4. The inmate juvenile sports and exercise programs must be prevented from delinguency, and then be developed into direction preventing it. 5. A special sports and exercise programs must be developed for a potential force of the inmate juvenile.

오프라인 프로그래밍을 이용한 스카라 로봇의 비쥬얼 피드백 제어

신행봉,이우송,이현철,한성현 한국공작기계학회 2004 한국공작기계학회 춘계학술대회논문집 Vol.2004 No.-

The equipment of industrial robot in manufacturing and assembly lines has rapidly increased. In order to achieve high productivity and flexibility, it becomes very important to develop the visual feedback control system with Off-Line Programming System(OLPS). We can save much efforts and time in adjusting robots to newly defined workcells by using OLPS. A proposed visual calibration scheme is based on position-based visual feedback. The calibration program firstly generates predicted images of objects in an assumed end-effector position. The process to generate predicted images consists of projection to screen-coordinates, visible range test, and construction of simple silhouette figures. Then, camera images acquired are compared with predicted ones for updating position and orientation data. Computation of error is very simple because the scheme is based on perspective projection, which can be also expanded to experimental results. Computation time can be extremely reduced because the proposed method does not require the precise calculation of tree-dimensional object data and image Jacobian.

곡관 덕트내 난류 비정상유동의 압력분포

박길문,이행남,백대우,손현철 朝鮮大學校 機械技術硏究所 2000 機械技術硏究 Vol.3 No.1

In this study, Flow characteristics of turbulent unsteady flows in a square-sectional 180°curved duct were experimentally investigated. Experimental studies for air flow were conducted to measure pressure distributions in the square-sectional 180°curved duct by using a magnehelic differential pressure gage. The experiment were conducted in nineteen sections from the inlet (ø=0°) to the outlet(ø=180°) of the duct at 10°intervals. The results obtained from the experimentation are summarized as follows. (1) In the turbulent oscillatory flow, the pressure distribution was the largest in the accelerating and decelerating region of the bend angle of 90°and the pressure difference of the inner and outer walls was the largest before and after the bend angle of 90°. (2) In the turbulent pulsating flow, the pressure difference was the largest near the region of bend angle of 90°in the case of the middle region, and since then the pressure difference of the inner and outer walls became smaller.

과민성 장증후군 환자에서 베타 아드레날린 수용체 기능의 활성도와 불안 수준

강은호,이풍렬,이준행,김현서,이종철,유범희 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.1