肥肉豚의 血液化學値에 關한 硏究

李政吉,康炳奎,魏聖河,朴承柱,朴來生 全南大學校 農漁村開發硏究所 1981 農業科學技術硏究 Vol.16 No.1

全羅南道 順天地方을 中心으로 한 養豚場에서 出荷된 肥肉豚을 對象으로 血液化學値를 調査했다. 돼지의 年齡은 7個月부터 13個月이었으며, 總 276頭(♀ 181,♂ 95)를 對象으로 屠畜場에서 採血했는데 Landrace와 Berkshire의 一代難種이 大部分이었다. 한편 本 實驗에서 使用한 무??豚은 모두가 去勢한 것이었다. 1. 測定한 血液化學値는 血淸?萄糖量, 血淸總蛋白量, ablumin量, globulin量, 血淸尿素?素量, 血淸 cholesterol量, calcium量, 無機燐量, 血淸 transaminase(SGOT와 SGPT)等이었다. 2. 本 調査에서 나타난 각종 血液化學値의 範圍 및 平均値는 이미 報告된 結果와 거의 一致하였다. 3. 血淸cholesterol量은 性別差가 없었고 겨울에 높은値를 보인 反面, 여름과 가을에는 낮은 치를 보였다. 4. 血淸總蛋白量의 季節的變動은 globulin量의 變動에 起因한 것이었고, globulin量은 全般的으로 높게 나타났는데 特히 여름철의 增加가 뚜렷했다. Samples of blood were taken from 276 fattening pigs(181 intact females and 95 castrated males) at slaughter and serum chemical values were determined. The pigs were from Suncheone area, Chonnam Province; their age ranged 7 to 13 months; most of them were crossbreds of Landrace and Berkshire. 1. Determined blood chemical values in the prestent study were glucose, total protein, albumin, globulin, serum urea nitrogen, cholesterol, calcuim, phosphorus, serum glutamin oxalacetic transaminase and serum glutamic pyruvic transaminase. 2. The ranges and means of the chemical values in the present study were reconcilable with the normal values previously reported. 3. Sex differences between castrated males and intact prepubertal females were not observed in serum cholesteol levels. There were significant differences between the means of seasons, with the higher cholesterol values being observed during the winter as compared with summer and fall. 4. Seasonal changes of total protein cantent were due to the seasonal changes of globulin values. The globulin values in the present study were higher than those reported previously by others; the values were highest during summer season.

151종 생약제 추출물이 B형 간염 바이러스 표면 항원(HBsAg)과 항체(HBsAb)의 결합반응 그리고 HBV DNA polymerase 활성에 미치는 효과 : 한국산 각종 생약제를 이용한 B형 간염치료제의 개발

정태호,김정철,김문규,이인선,채성철,김승래,정준모,이인수,김승호,함경수 慶北大學校 醫科大學 1992 慶北醫大誌 Vol.33 No.3

세계인구 43억명 중 B형 간염 바이러스 보균자는 2억 1천 5백만명이며 이중 78%인 1억 6천만명 이상이 아시아 대륙에 집중되어 있다. 한국도 B형 바이러스 간염의 침윤지대이다. 본 연구는 B형 바이러스 보균자 혹은 만성간염을 치료할 수 있는 생약제를 탐색할 목적의 일환으로 한국에서 시판하는 생약제 151종을 구입하여 증류수로 추출하고 여과한 후 냉동건조하여 HBs 항원에 대한 결합능, HBV DNA polymerase억제능, tumor necrosis factor(TNF) 유리에 미치는 영향, 그리고 galactosamine 유발 간염에 대한간장보호 작용을 조사하였다. 151종의 생약제중 0.16㎍/㎖ 농도에서 간염 vaccine 내에 함유된 HBs 항원과 결합하는 생약제는 지유, 가자, 복분자, 대황, 정향, 빈량, 산수유, 소목, 마황, 쇄양, 후박, 목과, 양강, 오약, 산사, 목단피 등 16종이었다. 이들 생약제중 대황(Rheum palmatum L. 大黃), 가자(Terminalia chebula R. 訶子), 지유(Sanguisorba officinalis L. 地楡), 복분자(Rubus coreanus M. 覆盆子)는 HBV DNA polymerase 활성도를 비교적 강하게 억제하였으며 빈량(Areca catechu L. 빈랑), 정향(Eugenia caryophyllata T. 丁香), 목과(Chaenomeles japonica L. 木瓜), 산수유(Cornus officinalis S. 山茱萸)는 약하게나마 HBV DNA polymerase 활성을 억제하였다. 또한 HBV DNA polymerase를 억제한 대황, 가자, 지유, 복분자, 빈량, 정향, 마황, 소목, 산수유를 대상으로 TNF 유리에 미치는 영향을 조사한 결과 소목을 제외한 8종의 생약제 모두가 대식세포를 자극하여 TNF를 유리시켰다. 그리고 장차 임상에 사용함을 전제로 HBV DNA polymerase를 억제한 대황, 가자, 지유, 복분자, 빈량, 정향, 마황, 소목, 산수유를 galactosamine 유발 간염(백서)에 투여하여 간기능 검사에 미치는 효과를 조사하였으나 간기능 검사상으로는 특별한 보호작용을 나타내지 못하였으며 생약제 단독 투여로서는 간기능에 대하여 나쁜 영향을 주지 않았다. Hepatitis B virus infection is major cause of acute and chrome hepatitis, cirrhosis of liver, and hepatocellular carcinoma. There are over 200 million carriers of hepatitis B virus in the world, nearly 80 % of whom live in the South East Asia, Korea is also highly endemic area of hepatitis B virus infection. This study was performed to evaluate the effect of extracts of traditional Korean herbal medicines on hepatitis B virus. 151 traditional herbs were extracted, filtered and lyophilized. Using 151 herbal extracts we tested binding capability to the HBs Ag, inhibition of HBV DNA polymerase, release of tumor necrosis factor (TNF), and protection against galactosamine induced liver damage. Among 151 herbs, 16 herbs (Sanguisorba officinalis L., Terminalia chebula R., rubus coreanus M., Rheum palmatum L., Eugenia caryophyllata T., Areca catechu L., Cornus officinalis S., Caesalpinia sappan L, Ephedra sinica S., Cynomorium songaricum R., Machilus thunbergii S., Chaenomeles japonica L., Alpinia officinarum H., Lindera strychnifolia V., Crataegus pinnatifida B., Paeonia suffruticasa A. ) had binding capability to HBs Ag which contained in the commercial hepatitis vaccine, at 16 ug/㎖ of concentratioa Among the above 16 herbs, Rheum palmatum L., Terminalia chebula R., Sanguisorba officinalis L., Rubus coreanus M. significantly inhibited the HBV DNA polymerase activity, and Areca catechu L., Eugenia caryophyllata T., Ephedra sinica S., Caesalpinia sappan L., Chaenomeles Japonica L., Cornus officinalis S. also inibited the HBV DNA polymerase activity but less effective. All of the herbs, except Caesalpinia sappan L., which inhibited the HBV DNA polymerase activity, actively stimulated the mononuclear cells to release tumor necrosis factor(TNF) in whole blood culture system. The herbs which inhibited the HBV DNA polymerase activity, did not show any protective effect in galactosamine-induced hepatitis in rats, but there was no direct toxic effect when herbs were administered alone.

칼라 화상 합성을 위한 윤곽선 추출 고속화 알고리즘에 관한 연구

황인선,김희수,박경우,조정래,위승정 광주보건대학 1998 論文集 Vol.23 No.-

This Paper describes a contour extraction algorithm for color image composition. When a new image is compoended with an object cut from many images, it is important to extract contour f the object. The principal way of extracting contour suggested the method that the contour of an object is drawn with a thick line, and the line is made a thin line by spacial differental value if input image. But in that case, as there is an defect which takes processing the above mentioned method.

Effect of Pressure-Assisted Thermal Processing on the Inactivation of Bacillus stearothermophilus in cooked ground beef, egg patty, milk, and mashed potatoes

Lae-Seung Jung,Jeongjin Kim,Geun-Pyo Choi,V. M. Balasubramaniam,Juhee Ahn 한국식품영양과학회 2015 한국식품영양과학회 학술대회발표집 Vol.2015 No.8

Effect of Atmospheric Pressure Plasma Treatment on Au Flip Chip Bumps Bonded with Cu Circuit on Glass Using Ultrasonic Energy

Jung-Lae Jo,Ja-Myeong Koo,Jong-Bum Lee,Seung-Boo Jung 한국표면공학회 2008 한국표면공학회 학술발표회 초록집 Vol.2008 No.-

Effect of Atmospheric-Pressure Plasma Treatment on the Joint Strength between Au Flip Chip Bumps and Cu-Finished Si Wafer Substrates Bonded Using Ultrasonic Energy

Jung-Lae Jo,구자명,이종범,이종균,전성호,김종민,문정훈,Seung-Boo Jung 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.54 No.3

This study investigated the effects of the conditions of atmospheric-pressure plasma (APP) treat- ment on the ultrasonic bonding property of Au flip chip bumps on Cu-finished silicon substrates. The substrate underwent the de-ionized (DI)-water spreading test and a surface analysis using Auger electron spectroscopy (AES) after plasma treatment had been performed for various treat- ment times from 0.3 s to 18 s with three different gases: N2, N2+O2 and N2+H2. The treatment conditions greatly affected the spreading angle and the joint strength. The gases containing O2 and H2 were effective in improving the wettability of the substrate and the bondability between the Au bump and the Cu substrate, respectively. This study investigated the effects of the conditions of atmospheric-pressure plasma (APP) treat- ment on the ultrasonic bonding property of Au flip chip bumps on Cu-finished silicon substrates. The substrate underwent the de-ionized (DI)-water spreading test and a surface analysis using Auger electron spectroscopy (AES) after plasma treatment had been performed for various treat- ment times from 0.3 s to 18 s with three different gases: N2, N2+O2 and N2+H2. The treatment conditions greatly affected the spreading angle and the joint strength. The gases containing O2 and H2 were effective in improving the wettability of the substrate and the bondability between the Au bump and the Cu substrate, respectively.

증숙 및 발효 더덕의 이화학적 특성 및 생리활성 변화

정래승(Lae-Seung Jung),윤원병(Won-Byung Yoon),박성진(Sung-Jin Park),박동식(Dong-Sik Park),안주희(Juhee Ahn) 한국식품과학회 2012 한국식품과학회지 Vol.44 No.1

본 연구에서는 증숙 및 발효에 의한 더덕(Codonopsis lanceolata)의 이화학적 특성과 생리활성의 변화에 미치는 영향에 대해 조사하였다. 건조된 더덕 시료를 증숙처리한 후 Lactobacillus rhamnosus를 접종하여 37℃에서 7일간 혐기적 조건에서 발효시켰다. 비증숙과 비발효 더덕추출물(NS-NF)을 대조군으로 하여 처리군에는 비증숙과 발효 더덕추출물(NS-LF), 증숙과 비발효 더덕추출물(S-NF), 증숙과 발효 더덕추출물(S-LF)을 포함한다. 총 폴리페놀성 화합물 함량은 NS-NF(8.9 mg GAE/g)와 비교하여 S-NF와 S-LF에서 유의적으로 증가되었다(26 mg GAE/g). 총 플라보노이드 함량은 S-NF(8.1 mg RE/mL)와 S-LF(7.8 mg RE/mL)에서 가장 높았다. S-NF와 S-LF의 EC<SUB>50</SUB> 값이 각각 0.8과 0.6 mg/mL으로 높은 항산화능을 보였다. Staphylococcus aureus, Listeria monocytogenes, Salmonella Typhimurium, Shigella boydii의 생육은 S-LF에 의해 효과적으로 저해되었다(MIC<9 mg/mL). NS-NF(EC<SUB>50</SUB><17 mg/mL)에 비교하여 NS-LF와 S-LF(EC<SUB>50</SUB><6 mg/mL)가 가장 높은 α-glucosidase와 tyrosinase 저해효과를 나타냈다. Aacetylcholinesterase(AChE)는 S-LF(IC<SUB>50</SUB><32 mg/mL)에 의해 효과적으로 저해되었다. 따라서 본 연구의 결과는 증숙에 의해 더덕의 총 페놀함량, 플라보노이드 함량, 항산화능이 향상되었으며 발효에 의해 특이적으로 항미생물 효과, 효소활성저해 및 인지기능 개선 등과 같은 생리활성을 효과적으로 증진시켰다. This study was designed to evaluate the physicochemical properties and biological activities of steamed and fermented Codonopsis lanceolata. The treatments included NS-NF (non-steamed and non-fermented), NS-LF (non-steamed and L. rhamnosus fermented), S-NF (steamed and non-fermented), and S-LF (steamed and L. rhamnosus fermented). Total polyphenol amounts of S-NF and S-LF were significantly increased to more than 26 mg GAE/g. The highest DPPH scavenging activities were observed for S-NF and S-LF, showing EC<SUB>50</SUB> values of 0.8 and 0.6 mg/mL, respectively. The growths of Staphylococcus aureus, Listeria monocytogenes, Salmonella Typhimurium, and Shigella boydii were effectively inhibited by S-LF (MIC<9 mg/mL). The NS-LF and S-LF (EC<SUB>50</SUB><6 mg/mL) effectively inhibited α-Glucosidase and tyrosinase activities compared to NS-NF (EC<SUB>50</SUB><17 mg/mL). The S-LF exhibited the highest acetylcholinesterase (AChE) inhibitory activity (IC<SUB>50</SUB><32 mg/mL). Therefore, the results suggest that the application of the steaming process combined with probiotic fermentation can effectively enhance the biological and pharmacological activities in C. lanceolata.

Identification of small molecules inducing apoptosis by cell-based assay using fission yeast deletion mutants

Kyung-Sook Chung,Nam-Hui Yim,Seung-Hee Lee,Shin-Jung Choi,Sun-Jung Cho,Yoo-Jin Jung,Jung-Eun Kang,Kwang-Lae Hoe,Dong-Uk Kim,Kyung-Bin Song,Julian Simon,Misun Won 한국생물공학회 2008 한국생물공학회 학술대회 Vol.2008 No.10

Relative Bradycardia in Scrub Typhus

Jung, Lae Young,Jeon, Mir,Choi, Seung Hee,Hwang, Joo-Hee,Lee, Chang-Seop,Rhee, Kyoung-Suk Allen Press, etc 2017 The American journal of tropical medicine and hygi Vol.97 No.5

<P>To investigate the relationship between heart rate and temperature, we examined 493 febrile patients with documented disease. These patients were diagnosed serologically and analyzed retrospectively: 337 (68.4%) responded to fever with increased heart rate < 10 beats/minute/degrees C (relative bradycardia [RB]), and 156 patients had a heart rate response >= 10 beats/minute/degrees C (general heart rate increase [GHRI]). The RB group had a higher median resting heart rate and lower heart rate at maximum temperature than the GHRI group. Despite differences in heart rate response, no significant differences were seen in clinical outcomes (acute kidney injury, systemic inflammatory response syndrome (SIRS), and death). We concluded that most patients with scrub typhus presented with RB. In scrub typhus infection, RB can be included as one of the clinical features for differential diagnosis from other infectious diseases.</P>

경추손상 환자에서 기관절개술후 상태에서 실시한 전방경유 수술

정현식,성주경,김대현,황성규,함인석,박연묵,김승래 대한신경외과학회 1997 Journal of Korean neurosurgical society Vol.26 No.6