그람양성구균에 대한 Teicoplanin과 Vancomycin의 시험관내 항균력

최태열,김경숙,전용관,서일혜,김정욱,이웅수,안정열,김홍석,정재용,최효선,김덕언,유진우 대한감염학회 1994 감염 Vol.26 No.1

An increasing frequency of methicillin resistant S. aureus(MRSA), methicillin resistant coagulase negative staphylococci(MRCNS) and Enterococcal infection have been observed in recent years. Teicoplanin is a new glycopeptide antibiotic obstained from the Actinoplanes teicomycetius. The molecular structure and spectrum of antimicrobial activity of teicoplanin is simillar to those of vancomycin, and has been reported to have an excellent in vitro and in vivo effect against various gram-positive infections. Therefore, we evaluated the in vitor susceptibility of gram positive cocci, such as, S. aureus, coagulase negative Staphylococci(CNS), and Enterococci to teicoplanin and vancomycin. The total 253 strains consisted of MSSA(40), MRSA(53), MSCNS(47), MRCNS(48), and Enterococci(65). They were assayed by disc diffusion and agar dilution. During the study, 57% of S. aureus and 49% of CNS showed resistance to methicillin. The inhibitory diameter of teicoplanin was 15-20mm in MSSA, 12-19mm in MRSA, 13-24mm in MSCNS, 11-23mm in MRCNS, and 15-22mm in Enterococci respectively, and showed sensitivity in all but 8 strains(3.2%). The range of the minimum inhibitory concentration (MIC) of teicoplanin to MSSA, MRSA, MSCNS, MRCNS and Enterococci were 9.12-2.0㎍/ml, 0.25-2.0㎍/ml, & 0.25-32㎍/ml, 0.12-1.0㎍/ml respectively. One case of S. haemolyticus was resistant to teicoplanin (32㎍/ml) by the agar dilution method. Eight minor (3.2%) and one major(0.4%) error was observed when the MIC and disk diffusion data were correlated with teicoplanin. As for vancomycin the inhibitory diameter was 17-21mm in MSSA, 15-21mm in MRSA, 18-26mm in MSCNS, 18-25mm in MRCNS, and 16-22mm in Enterococci respectively. The range of the MIC of vancomycin to MSSA, MRSA, MSCNS, MRCNS, and Enterococci were 0.25-1.0㎍/ml, 0.25-4.0㎍/ml, 0.5-2.0㎍/ml and 0.5-2.0㎍/ml respectively. One minor error (0.4%) was seen with the vancomycin disk. The MIC90 of MSSA and MRSA exhibited the same results in teicoplanin (1.0㎍/ml, 1.0㎍/ml), and vancomycin(2.0㎍/ml, 2.0㎍/ml). MSCNS and MRCNS exhibited greater MIC90 with teicoplanin(4.0㎍/ml, 8.0㎍/ml) than vancomycin(2.0㎍/ml, 2.0㎍/ml). Incontrase Enterococci were more susceptible to teicoplanin(0.5㎍/ml) than to vancomucin (2.0㎍/ml). Results from this analysis indicated that both teicoplanin and vancomycin were very excellent for gram positive infections, especially those resistant to methicillin.

고혈압 환자에서 경동맥 신전성의 변화

허영선,김학진,송영빈,안지현,임성훈,이왕수,김상욱,김태호,김치정,류왕성,유언호 중앙대학교 의과대학 의과학연구소 2000 中央醫大誌 Vol.25 No.3

海雲台 海濱變形에 관한 硏究

閔丙亨,姜龍太,朴雲龍,金嘉也 동아대학교 공과대학 부설 한국자원개발연구소 1984 硏究報告 Vol.8 No.1

This study has been carried out to determine the values of bed-sand scale and time scale which are difficult at hydraulic model tests on the HAE UN DAE beach after performing a marine investigation required to establish a protection method about the deformation of HAE UN DAE beach by using hydraulic model test. The amount of topography deformation of HAE UN DAE beach has also been obtained by the two dimensional movable bed hydraulic model test in a quantitative way.

남성 건강검진 수진자에서 간기능 장애 및 비알코올성 지방간과 대사 증후군과의 관련성

최태성,유재영,김진석,장은철,박주언,김병익 순천향의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.2

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지단백 대사 기전에 대한 문헌 고찰

김태운,박태곤 부산대학교 과학교육연구소 2006 교사교육연구 Vol.45 No.-

Atherosclerosis, along with the resultant coronary artery disease (CAD), is a leading cause of mortality in industrialized countries. Lipoproteins (LP) are generally classified according to their density. Triglycerides are mainly transported in chylomicrons and very low density LP (VLDL), cholesterol is mainly transported in low density LP (LDL) and high density LP (HDL). The metabolism of LP is controlled by their apolipoproteins, by specific receptors, enzymes, and transfer proteins. Lipoprotein receptors are membrane proteins which play a central role in lipid metabolism. The low density lipoprotein (LDL) receptor recognises lipoproteins containing apolipoprotein B100 or an activated form of apo E. The LDL receptor therefore mediates the uptake of intermediate density lipoprotein (IDL) and LDL by the liver, and it also facilitates uptake of LDL by other tissues. Cellular cholesterol efflux is mediated by HDL, acting in conjunction with the cholesterol esterifying enzyme, lecithin: cholesterol acyltransferase (LCAT). Cholesterol ester accumulating in HDL can then follow a number of different fates: uptake in the liver in HDL containing apolipoprotein (particle uptake) by LDL receptors, selective uptake of HDL cholesterol ester in liver or other tissues involving scavenger receptor B1 (SRBI), or transfer to triglyceride-rich lipoproteins as a result of the activity of cholesterol ester transfer protein (CETP), with subsequent uptake of triglyceride-rich lipoprotein remnants in the liver. CETP promotes the transfer of cholesterol esters (CE) from antiatherogenic HDLs to proatherogenic apolipoprotein B (apoB)-containing lipoproteins, including VLDLs, VLDL remnants, IDLs, and LDLs. A deficiency of CETP is associated with increased HDL levels and decreased LDL levels, a profile that is typically antiatherogenic. Recently, another key molecule involved in this pathway was identified, scavenger receptor BI ; this mediates the selective uptake of HDL cholesterol esters in the liver and thus constitutes a pathway of reverse cholesterol transport parallel to that mediated by CETP. Thus, the remodeling of human HDL by CETP, involving CE;-TG interchange, followed by the action of hepatic lipase (HL), leads to the enhanced uptake of HDL CE by cellular SR-BI. These observations suggest that in animals such as humans in which both the selective uptake and CETP pathways are active, the two pathways could operate in a synergistic fashion to enhance reverse cholesterol transport. In conclusion, a major challenge will be to determine if manipulation of RCT pathway by targeting molecules such CEPT, LCAT, HL, or SRBI can be used for therapeutic benefit.

뇌 심혈관계 관련질환 유소견 근로자들의 의료이용에 관한 연구

최태성,유재영,김진석,장은철,박주언,우극현 순천향의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.2

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규칙적인 유산소성 운동이 비만아동들의 신체구성 및 호흡순환기능에 미치는 영향

김태운,신군수,김종인,이광무,김성헌,안병철,고기준,한재웅,이재규 釜山大學校 附設 體育科學硏究所 1997 體育科學硏究所 論文集 Vol.13 No.-

The purpose of this study was to examined the effect of supervised regulary aerobic exercise program with cardiorespiratory function of obese children. The subjects were 16 obese Childrens(elementary school 4∼5 grade), and engaged in regulary aerobic exercise program for 9 weeks(5 days/week, 100 min/day, 60∼70% HRmax) with mountain climbing, basketball and football. The items of cardiorespiratory function measured VEmax, HRmax, RQmax, VCO₂max, VCO₂max, VCO₂max/kg and BFmax after treadmill exercise load. The conclusion of this study was as follows ; 1. In body composition, there were significant decrease(P<0.001) after aerobic exercise for 9 weeks in body weight, percent body mass index 2. In cardiorespiratory function, there were significant increase(P<0.001) after aerobic exercise for 9 weeks in VEmax and VCO₂max by treadmill exercise load. 3. In cardiorespiratory function, there were significant increase(P<0.001) after aerobic exercise for 9 weeks in VO₂mex and RQmax by treadmill exercise load. 4. In cardiorespiratory function, there were significant increase(P<0.001, P< 0.01) after aerobic exercise for 9 weeks in VO₂max/kg and BFmax by treadmill exercise load.

비만치료의 원리와 대책

김태운 釜山大學校 附設 體育科學硏究所 2005 體育科學硏究所 論文集 Vol.21 No.1

The increasing prevalence of obesity and its concomitant health risks justify widespread efforts toward prevention. This review has considered in detail the potential ability of physical activity, dietary, and lifestyle modification interventions to reduce the prevalence of obesity. ......

인터넷 웹을 기반으로 한 공정규명과 공정제어 교육 시스템

김태언,이범석 경희대학교 산학협력기술연구원 2002 산학협력기술연구논문집 Vol.8 No.-

As the computer systems are developed rapidly, the area of the engineering softwares are also expanded. Most of these engineering softwares are the high-priced commercial softwares for the exactness of the results. However, the commercial softwares are too expensive for some users. especially undergraduate students. In this study, the engineering software for the chemical process control is made of the JAVA language in a web environment. Then the virtual experiment of the process control can be executed free of charge using this software. This software is worked on the internet and shows how to identify a unknown process system and how to tune the control parameters to operate the process system. The numerical examples are presented to illustrate the virtual experiment for the process control using the software made in this study.

大學 男女 球技選手들의 最大無機的 Power

김태운,유재충,안덕균,선우섭,이한,손두욱,박충서 慶熙大學校 社會體育硏究所 1994 體育科學論叢 Vol.- No.7

The purpose of the present research is to compare characteristics of maximal anaerobic power observed in different types of sports and player's sex differences. We have reached the following conclusions from the results we obtained by measuring maximal anaerobic power and blood lactate concentration of 60 elite university male and female players during the exercise of bicycle ergometer: 1. As to absolute and relative values of maximal anaerobic power, male players are higher in the order of rugby and handball, whereas female players are higher in the order of hockey and soccer, but no significant differences are observed between types of sports. 2. Male players are noticably higher in absolute values of maximal anaerobic power(p<0.001), but relative value is very simi1ar to that of female players. 3. It is estimated that the fact, that female players show obvious higher mean anaerobic power(p<0.001) during the 3,4KP excercise is due to sex differences in ocdurrence work load of maximal anaerobic power. 4. Comparison of blood lactate concentration at each work load in different types of sports and player's sex differences show an increase in proportion to mean anaerobic power. The results given above clearly show the differences between the type of sports such as rugby and hockey requiring power and speed, and the type of sports such as handball and soccer requiring edurance.