상징 해석 方法論에 대한 試論 : 질베르 뒤랑을 중심으로

秦炯俊 弘益大學校 1982 弘大論叢 Vol.14 No.1

Nous savons que la pense´e occidentale et spe´cialement la philosophie franc¸aise a pour constante tradition de de´valuer ontologiquement l'image et philosophiquement la fonction d'imagination 《mai^tress d'erreur et de faussete´》. Dans ce petit cahier, nous constaferons, en examinant les notions sur 1'imagination symbolique de Sartre, Freud, Jung, Bachelard, que 1'imagination se re´ve`le comme le facteur ge´ne´ral d'e´quilibration psycho-sociale. Chez Durand, l'imagination, loin d'e^tre une ide´e a` 1'e^tat naissant ou 1'enfance de la conscience, est une principe ge´ne´rali sateur de toute 1'activite´ humaine. I1 s'inte`rroge, sans renier le de´cisif he^ritage du philosophe de la Re^verie poe´tique, sur la totalite´ de l'imaginaire et ge´ne´ralise 1'anthropologie de l'imaginaire. Ce petit cahier n'a 1'intention que de pre´senter une partie de sa vaste champ de the`orie.

유산균(L.lactis CBT-8)및 발효 추출물의 Helicobacter pylori 억제 능력

진춘조,박형석,이혜운,김성렬,강동구,이준상,이재동,왕준호 건국대학교 의과학연구소 2002 건국의과학학술지 Vol.12 No.-

Helicobacter pylori infection was the cause of chronic gastritis, duodenal ulcer and gastric MALT lymphoma. The eradication rates of H. pylori using antibiotics are around 80%. Lactobacilli have been demonstrated to have in vivo and in vitro inhibitory effects on H. pylori infection. We aimed to evaluate the inhibitory effect of L. lactis CBT-8 and its extract on H. pylori in human stomach. Thirty-five H. pylori-infected volunteers(30-49 yr)were randomized into two groups which were treated with L. lactis CBT-8 and its extract(Group A n=17) or milk containing L. lactis CBT-8(Group B, n=18). They underwent 13C-urea breath tests before and after treatment. The DOB30 of group A(n=14) was decreased 41.0% after treatment(26.0±4.9 before, 15.3±2.1 after treatment)(p<0.05). the DOB30 of group B(n=13) was decreased 22.3% after treatment(22.0±2.2 before, 17.1±1.7 after treatment)(p<0.05). In conclusion, L. lactis CBT-8 was effective in suppressing H. pylori infection in human stomach.

심실 조기 수축의 발생 부위 및 연결 간격의 차이에 따른 혈역학적 변화

진승원,김재형,노태호,조은주,김희열,이만영,김종진,박준철,채장성,홍순조,최규보 대한순환기학회 1999 Korean Circulation Journal Vol.29 No.7

비만 펩티드 백신의 효능에 영향을 미치는 구조적 요소

김형진,이희종,김효준 한양대학교 이학기술연구소 2007 이학기술논문지 Vol.10 No.-

Apo B-100 is a constitutive component of low density lipoprotein (LDL) of which functions in packaging, transport, and absorption of lipids. Extortive binding of anti B4-antibody onto Apo B-100 should inhibited the functions of Apo B-100. Previously, we had showed that the peptide B4 induced antibodies recognized Apo B-100 and thus elicited anti-obesity effect. In this study, we compared the efficacy of peptide vaccine against obesity and of antibody inducing immune response by introducing additional peptides fused to B₄ Peptide. Previously, we had constructed B₄T, introducing additional peptides fused to the C-terminal of B₄ peptide, and BTB, fused to the middle of B₄ peptide, with preS2 of HBV. Then we manufactured vaccines, and vaccinated on C57BL/6 mouse. We measured weight of mice 3 days a week and, after vaccinating, we gathered blood and performed ELISA in interval 2 weeks for indicating antibody inducing immune response. Among these two artificial vaccines, B₄T was better Vaccine against obesity than another. But BTB was batter efficient inducer of the antibody against B₄. These result explains that B₄ tetramer is very crucial structural factor to operate as an obesity vaccine. Apo B-100은 low-density lipoprotein의 구성 요소로서 지방의 패키징, 운송, 흡수를 담당한다. App B-100에 anti B4-antibody의 인위적 결합은 이러한 Apo B-100의 기능을 저해할 것이다. 선행 연구에서 B4 펩티드에 의해 유도된 antibody가 Apo B-100을 인지하고 그에 따라 비만억제 효과를 나타내는 것을 확인하였다. 본 연구는 비만에 대한 B cell epitope을 4번 반복한 B4 펩티드에 추가적인 펩티드를 연결한 두 가지의 백신을 사용하여 효능을 비교하였다. HBV의 preS2를 B4의 C-terminal에 연결한 B₄T와 중간에 삽입시킨 BTB를 제조하여 C57BL/6 마우스에 주사하였다. 일주일에 3회 마우스의 체중을 측정하였고, 백신 주사는 2주 간격으로 4회 실시하였으며, 백신 주사 후 2주 간격으로 혈액을 채취하여 면역 반응에 의해 유도된 antibody를 indirect Enzyme -Linked Immunosorbent Assay에 의해 측정하였다. 두 가지 백신 사이에서 체중 증가 억제율로 본 비만에 대한 백신효과는 B₄T가 더 우수하였다. 그러나 B₄T에 비해 BTB가 유도된 antibody의 titer와 혈중 지속 시간이 더 우수했다. 이런 결과는 B펩티드가 항체유도에 있어서 중요하지만, 비만억제 기능에 있어서 B₄ tetramer가 매우 중요한 인자임을 입증하였다.

禁止錯誤에 있어서 責任阻却의 限界 : 전문가의 조언을 신뢰한 각국의 판례를 중심으로

金亨埈,朴相珍 건국대학교 사회정책연구소 1998 사회과학연구 Vol.9 No.-

응급실을 내원한 65세 이상 노인 환자의 분석

김진년,김태훈,강양욱,오명,김상철,김성훈,권계형,남홍우,이홍순,유형준 대한노인병학회 2001 대한노인병학회지 Vol.5 No.3

가토 간의 VX2 carcinoma : 종양이식방법에 따른 영상소견의 차이 Different Radiologic Features According to Innoculation Methods

이준우,정진욱,최국명,김종재,김세형,최준일,이경호,김승협,박재형 대한초음파의학회 2000 ULTRASONOGRAPHY Vol.19 No.3

양성과 음성 정신분열증에 관한 연구 : 일반적 특성 병전적응도와 인지기능을 중심으로 Focused on General Characteristics, Premobid adjustment and Cognitive Function

박준형,윤진상,이형영 大韓神經精神醫學會 1988 신경정신의학 Vol.27 No.1

Most clinicians agree that the group of disorders called schizophrenia is heterogeneous. Since Kraepelin described dementia praecox, various attempts have been taken to subdivide schizophrenia into several homogeneous subtypes. Recently some investigatiors were interested in the division of schizophrenia by use of positive & negative symptomatology that Hughlings-Jackson had tried. Crow especially hypothesized that there were some differences between the tow prominent symptoms(negative & positive) in respect of premorbid adjustment, response to neuroleptic therapy and underling pathologic process etc. But this hypothesis remains largely untested. Using Andreasen & Olsen's criteria for negative, positive and mixed schizophrenia, we subdivided a consecutive sample of 67 schizophrenic patients into 3 subtypes (negative 21, positive 23, mixed 23). We then evaluated some characteristic aspects among these 3 subtypes. The results are as follow : 1) There was s significant difference in mean age among the three subtypes. In the negative group, the mean age was most high and this was followed by the positive group(p<0.05). 2) There was a significant difference in the duration of education among the three subtypes. In the negative group, the duration of education was least and this was followed by the positive group(p<0.05). 3) There was a significant difference in premorbid adjustment among the three subtypes. The level of premorbid adjustmentwas lowest in the negative group and this was followed by the positive group.(p<0.005). 4) There was a significant difference in the number of previous hospitalizations among the three subtypes. In the negative group, the number of hospitalizations was lowest and this was followed by the positive group.(p<0.005). 5) The experience of previous modern psychiatric treatment was more reare in the negative group and this was followed by the positive group.(p<0.05). 6) The score of mini mental status for evaluation of cognitive function was significantly lower in the negative group and this was followed by the positive group.(p<0.001). 7) The scores of the BPRS for evaluation of psychotic symptoms at the times of admission and 4 weeks later were significantly most high in the positive group and this was followed by the mixied group (p<0.05, respectively). The therapeutic response rated on the BPRS after 4 weeks, was significantly prominent in the positive & mixed groups(p<0.05, respectively), but not in the negative group. 8) Besides these, there were no significant differences in occupation, onset of age, duration of illness and family history among the three subtypes. .

18S-srRNA 분석에 의한 Acantbamoeba 한국 분리주들의 분류 검토

신호준,지영진,조명수,김형일,박연희,임경일 아주대학교 의과학연구소 1998 아주의학 Vol.3 No.2

Acanthamoeba spp. spread in soil, ponds, air and swimming pool, cause a granulomatous amoebic meningitis and amoebic keratitis in human and experimental animals. Their classification had depended upon morphological characteristics and physiological conditions such as thermophilic status and generation times. However, because amoeba species showed the morphological and physiological diversity in isolates, many attempts have been made on identification of Acanthamoeba spp. Restriction fragments length polymorphism (RFLP) analysis of IBS-small subunit ribosomal RNA (srRNA) was an useful tool for classification among morphologically and genetically closely-related species. In this study, 18S-srDNAs of amoebae were amplified by PCR with primer encoding 18S-srRNA gene and digested with restriction endonudeases, and RFLP analysis was applied on classification of Acanthamoeba Korean isolates (YM-4, YM-5 and YM-7), comparing with reference amoebae, A. culbertsoni, A. polyphaga and A. royreba. Trophozoites of six Acanthamoeba spp. had typical acanthopoda, but did not show any morphological differences. Cyst of Acanthamoeba sp. YM-7 was similar to that of A. polyphaga which was designated as group Ⅱ Acanthamoeba. Morphologically other amoebae belonged to group Ⅲ Acanthamoeba. Digestion of 18S-srDNA with six enzymes, Dde Ⅰ, Hae Ⅲ, Hind Ⅲ, EcoR Ⅰ, Rsa Ⅰ and Sph Ⅰ, resulted in various DNA fragments. Using the method of Nei and U (1979) for RFLP analysis, genetic divergence was not observed between A culbertsoni and Acanthamoeba sp. YM-4. Between A. culbertsoni and Acanthamoeba sp. YM-5, genetic distance was 0.070, 0.364 between Acanthamoeba sp. YM-4 and A. polyphaga, and 0.277 between Acanthamoeba sp. YM-7 and A. polyphaga. In comparison with A. culbertsoni and A. polyphaga, Acanthamoeba sp. YM-7 showed genetic distance of 0.330 and 0.154, respectively. Thus, Acanthamoeba sp. YM-7 is a similar species to A. polyphaga. Acanthamoeba sp. YM-5 is a different species from A. polyphaga, but closely-related to A. culbertsoni. Acanthamoeba sp. YM-4 can be classified as a subspecies or a strain of A. culbertsoni.

사회체육 참여자들의 정신건강에 관한 요인분석

박진성,박형준 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.3

This study was intended to systematically understand relevant variables among demo-sociology and sport-related ones of regular participants in the activities of sport for all, which particularly had significant effects on mental health, and further provide useful data for positive environment setting which was to help elevate the participants' mental health level. For this purpose, a total of 543 adults, male and female, was chosen to inquire into the ten factors and the causal relation in regard to mental health. The results are as follows: 1. Demo-sociological variables In regard to demo-sociological variables that help improve the participants' mental health level, gender, age, religion and residential environment factors proved of significant effects, while as another environment factors favorable for upgrading mental health level it could be generalized that man was more relevant than women, followed by the middle-aged and more than the young, small towns than big cities, and the religious than the atheists. 2. Sport-related variables In regard to sport-related variables which are helpful for upgrading the participants' mental health level, some variables classified by participation motives, forms, and careers, and the strength of activity had more significant effects, while the purpose of leisure activity rather than therapeutic purpose, free or of form of lover's society participation rather than scheduled lessons, high participation career rather than low career, and normal strength of activity rather than strong or weak in extreme can be generalized as positive environment variables favorable for upgrading mental health level.