Paraquat 중독환자의 초기검사로서 sodium dithionite를 이용한 소변내 paraquat검출의 임상적 의의

윤갑준,임경수,이진웅,김영식,이부수,박덕우,김선만,이강현,황성오,안무업 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

Background : Mortality from paraquat intoxication depends upon plasma paraquat concentration. To know the severity of paraquat intoxication is important for directing therapeutic modality and predicting prognosis. Sodium dithionite test for urinary paraquat provides an easy and simple method to determine the severity of paraquat intoxication in emergency department. purpose : To determine whether the result urinary paraquat test by sodium dithionite can predict outcome in patients with paraquat intoxication in emergency department. Subjects : 48 patients(male 31, female 17, mean age 37 years) who had exposure to paraquat and presented within 24 hours after exposure. Result : Thirty five patients were positive in paraquat urine test and thirteen patients were negative. Clinical manifestations were more severe in positive patients than in negatives. Complication was much more in positives than in negatives. 28 of 35 patients(80%) in positives and 2 of 13 patients(15%) in negatives died. Conclusion : Positive test for urinary paraquat is associated with high mortality and morbidity from paraquat intoxication, and qualitative test for urinary paraquat by sodium dithionite is an useful method to determine the severity of paraquat intoxication in emergency department.

아침형과 저녁형 사람에서 야간의 졸리움, 수행 및 체온의 비교

윤진상,국승희,신일선,신만식,최영,이무석,이형영 大韓睡眠-精神生理學會 1994 수면·정신생리 Vol.1 No.1

진행된 HIV 감염 환자에서 십이지장의 미란성 병변으로 발현한 Mycobacterium genavense 감염 1예

진상만,박종선,김홍빈,오명돈,최강원,김희연,국윤호,김남중 대한감염학회 2007 감염과 화학요법 Vol.39 No.4

Mycobacterium genauense는 최근에 알려진 미코박테륨으로서, 식욕 부진, 체중 감소, 설사, 림프절 병증 등 파종성 Myocobacterium avium-intracellulare complex 감염과 유사한 임상상을 보이며, 위장관 침범을 잘 하는 것으로 알려져 있으나 아직 국내에서 증례는 보고된 바가 없다. 저자들은 진행된 HIV 감염 환자에서 십이지장의 미란성 병변으로 발현한 Mycobacterium genavense 감염 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. 환자는 상복부 동통과 발열, 설사로 내원하였다. 십이지장의 미란성 병변에서 시행한 조직검사에서 항산균이 가득 차있는 거품세포가 관찰되었으며, 이 검체에서 16S rRNA 유전자의 중합연쇄반응 검사를 시행하여 Mycobacterium genavense를 확인하였다. Mycobacterium genavense, first identified in 1990, is known as a pathogen that mimics disseminated Myocobacterium avium-intracellulare complex (MAC) infection with particular propensity for the gastrointestinal tract. In Korea, no case with the organism has been reported. Herein we report a case of Mycobacterium genavense infection that manifested with erosive lesion of duodenum in a patient with acquired immune deficiency syndrome. The patient presented with epigastric pain and fever, diarrhea. Duodenal biopsy showed histiocytic infiltration with numerous acid-fast bacilli. Identification of the mycobacterial isolate by the polymerase chain reaction restriction analysis of 16S rRNA gene revealed Mycobacterium genavense.

만성 요통근로자의 능동적 운동프로그램 효과

허진강,송재철,노영만,박동식,양영애,김윤신 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.1

목적: 본 연구는 만성 요통근로자의 세 가지 능동적 운동프로그램 효과에 관한 연구로서 능동적 운동이 요추의 안정성 향상에 미치는 영향을 알아보고자 시도되었다. 방법: 3개월 이상 만성요통을 호소하는 64명의 근로자대상으로 무작위로 일반적인 물리치료그룹, 요추 운동그룹, 흉추 운동그룹, 세 그룹으로 나누었다. 능동적 운동 프로그램은 주 3회, 6개월 동안 실시하였으며, 통증강도, Oswestry 장애지수, 양손을 머리위로 최대한 올려 높이 측정, 요추부 경사각도를 평가하였다. 모든 대상자들은 연구 전, 연구 후 2주, 3개월, 6개월을 같은 측정방법으로 재평가하였다. 결과: 통증강도는 세 그룹 간에 통계적으로 유의한 차이가 없었다. Oswestry 장애지수는 연구 후 6개월에서 세 그룹 간의 유의한 차이가 있었으며, 요추운동그룹과 흉추운동그룹이 일반적인 물리치료그룹에 비하여 유의하게 감소하였다(p<0.05). 양손을 머리위로 최대한 올려 높이측정은 연구 후 3개월과 6개월에서 세 그룹 간에 유의한 차이가 있었으며, 연구 후 6개월에서는 흉추운동그룹이 일반적인 물리치료그룹과 요추운동그룹에 비하여 유의하게 증가하였다(p<0.05). 요추부 경사각도는 연구 후 2주와 3개월, 6개월에서 세 그룹 간에 유의한 차이가 있었으며, 연구 후 6개월에서는 흉추운동그룹이 일반적인 물리치료그룹과 요추운동그룹에 비하여 유의하게 감소하였다(p<0.05). 결론: 3개월 이상 만성 요통을 호소하는 근로자 대상으로 흉추의 운동성 증가를 위한 운동프로그램을 적용하여 흉추의 운동성을 증가시킨 결과에서 보면, 2주 시행하였을 때 요추의 신전 운동프로그램 보다 요추의 안정성 향상에 효과적이며, 6개월 시행하였을 때만, 요추의 심부근 근력강화 운동프로그램보다 요추의 안정성 향상에 효과적이었다. Oswestry 장애지수는 요추의 심부근 근력강화 운동프로그램과 동일하게 감소하였고, 통증강도는 세 그룹 모두 2주 시행하였을 때 감소하는 것으로 나타났다. Objective: To examine the relative efficacy of three active exercise programs for work-related, chronic low back pain, and to observe to what extent the programs affected the mechanical stability of the lumbar region. Methods: The subjects were 64 employees who were randomly divided into three groups to match the three active exercise programs which were performed 3 times a week for 6 months. All subjects were assessed with the same measurements at a pre-study examination, and then were reassessed at 2 weeks, 3 months and 6 months after the study. Results: The pain intensity didn' t show any significant difference among the three groups. However, the Oswestry Disability Index showed significant differences among the three groups at 6 months and the lumbar and thoracic exercise groups showed significant decreases compared to the general physiotherapy group (p<0.05). Maximal stretching with both hands in the overhead direction showed a significant difference among the three groups at 3 months and 6 months, and the thoracic exercise group at 6 months showed a significant increase in overhead stretching compared to the lumbar exercise and general physiotherapy groups (p<0.05). The lumbar region angle of inclination showed significant differences among the three groups at 2 weeks, 3 months and 6 months, with the thoracic exercise group being decreased significantly more than the lumbar exercise and general physiotherapy groups at 6 months (p<0.05). Conclusions: Exercise aimed at increasing thoracic mobility has an effect on lumbar stability. Furthermore, it is far more effective for lumbar stabilization than general physiotherapy and deep muscle strengthening lumbar exercise.

우수 사과酒酵母의 分離와 利用에 關한 硏究

朴允仲,金燦祚,李錫健,吳萬鎭,孫天培 충남대학교 농업과학연구소 1978 農業技術硏究報告 Vol.5 No.1

Extensive selection works on wild yeasts of fruits were carried cut to obtain strains which are applicable to apple wine making. Among the total number of 1,358 yeast strains which were isolated from various fruit samples collected from the vicinity of Daejeon and other regions of Korea, the strains SH-49, SH-129 and SH-338 were found to be useful. Then experiments on their morphological and physiological characteristics, and on the aspects of practical use in apple wine making were proceeded. The results obtained were as follows: 1. The strains SH-49 and SH-129, particularly SH-49, were appeared to have good fermentation ability, tolerance to sulfur dioxide and to produce fine quality of apple wine. 2. Apple wines made by using the strain, SH-49 and SH-129 contained less amount of total acids than those by other strains. 3. Apple wines of SH-49 and SH-129 were clarified rapidly during the primary fermentation period, and their absorbancy at 430 nm after 45 days of storage were approximately half of others. 4. Apple wine of SH-338 contained higher amount of residual sugar and its quality was superior to others. It is considered that this strain could be used in the production of apple wine of a characteristic quality. 5. The strains SH-49 and SH-338 were identified as a Saccharomyces cerevisiae according to Taxanomic Study of Yeasts by Lodder, however, classification of SH-129 was suspended for further study.

STD 61종 금형강의 이온질화처리에 관한 연구(Ⅰ)

안병만,김용길,차병묵,피윤섭,윤재홍,김진관 國立 昌原大學校 産業技術硏究所 1994 産技硏論文集 Vol.8 No.-

STD61종 열간금형강의 수명향상을 위하여 ion nitriding처리를 실시하였다. 이온질화전의 모재의 열처리시에는 1030˚C에서 quenching한 후 530˚C에서 2시간 tempering했을 때 Hv=600의 높은 경도값을 나타내었다. 580˚C, 600˚C에서 2시간 tempering했을 때는 각각 Hv=500, Hv=400으로 경도값이 오히려 감소했다. 이온질화 처리시에는 처리시간이 길고 N₂와 Ar첨가유량이 많을 수록 깊은 화합물층과 확산층을 얻었다. 그리고 각 처리조건에서 안정된 Hv=1150의 질화물층을 얻을 수 있다. Ion nitriding treatment has been practiced to improve the life of hot die steel of STD61. Before nitriding the parent STD61 tempered at 530˚C, 2hrs after quenching at 1030˚C, It showed the high hardness distribution of Hv=600. The hardness distribution has decreased by Hv=400, Hv=500 when tempered for 2hrs at 580˚C, 600˚C. In the ion nitriding, the more treat-time and the more N₂and Ar flux, the deeper the compounded layer and the diffused layer. The stable hardness, Hv=1150, of nitride layer was obtained at various treatment condition.

大邱地域 中小企業의 效率的인 技術開發 方案에 관한 硏究

全瑨文,張晩植,尹在坤,金圭昌,李栽燁,朴筍植,黃建夏 효성여자대학교 산업경영연구소 1988 경영경제 Vol.5 No.-

For modern business firms, the most important factor in determining comprtitiveness of a firm is technology, rather than capital. Technogical innovation is a driving force to develop an economy and is essential in growth and/or survival of a business firm. Following studies concerned with this subject, small business firms seem to be more efficient in technological innovation and developing new technology in several respects. Espercially in the new technology based industries, the small business firms have several advantages in technological innovation. In this study, we tried to show how to plan a technology development strategy in relation to management strategy when small business of theoretical and empirical study, we aimed to show the way to efficient management and procedure of technological innovation. For the research methodology, we firstly reviewed and analyzed current and previous studies about technological innovation strategy, efficient management, and selection of R&D projects. Secondly, the results of this theoretical study was examined empirically. The empirical study contains 153 questionaires and 30 interviews for business firms of this area. In addition, for the evaluation criteria for the selection of R&D projects, we sent questionaires to 60 professors who teaches R&D OR in university or college level. The result of these questionaires was analyzed and compared with that of the business firms of this area. The result of this empirical study shows that top management of small business firms should notice the importance of technological innovation and try to stimulate R&D activity. For the evaluation criteria for R&D projection, the criteria which could reduce the possibility of future uncertainty, maximize profit, and he suited for the situation of the business firm, should be established.

6·13 지방선거에 대한 유권자 의식과 평가 : 대구·경산지역의 설문조사를 중심으로

박성만,장성익,정진홍,권윤희 大邱大學校 社會科學硏究所 2002 社會科學硏究 Vol.10 No.1

이번 민선3기 지방선거는 여느 때와 달리 월드컵이라는 국제행사와 맞물려 유권자들의 투표율이 50%미만으로 관심이 매우 저조하였고, 지방선거에 대한 비관론이 대두되고 있는 가운데 바람직한 선거문화정착과 바람직한 후보자를 결정하는 것은 지방자치발전의 중요한 과제라 할 수 있다. 이러한 의미에서 본 연구는 6.13지방선거에 대한 유권자들의 의식을 평가하고 향후 지방선거의 발전성향을 제시하고자 하였다. 이를 이해 본 연구는 이번 2002년 6월 13일 실시된 지방선거에 관한 유권자들의 의식을 질문지를 통해 조사하고 분석하였다. 분석결과 이번 6.13 지방선거에 대한 유권자들의 의식은 전체적으로 지방정치와 지방선거 관심이 저조한 것으로 나타났으며, 이러한 원인은 여러 가지로 분석할 수 있으나 유권자의 무관심과 후보자들의 자질, 여러 가지 상황적 변수들이 복합적으로 나타난 결과라 할 수 있다. 유권자들의 선거에 대한 태도는 과거 여느때 보다 소극적이었으며, 결정시기와 결정방법에 있어서도 적극적인 참여가 부족하였다. 또한 6.13지방선거에서의 전체적인 유권자의 만족도는 낮게 나타났으며, 선거의 공정성, 주민참여정도, 법규준수정도, 관건개입정도는 지난 지방선거과 비교하여 낮거나 보통인 것으로 나타났다. 이는 지방선거에 대한 중요성을 일반 유권자들이 인식하지 못하고 있는 것으로 생각된다. 또한 지방선거에서의 문제점의 하나로 드러난 월드컵이라는 국제적 행사와 겹쳐 선거의 소홀로 나타난 지방정치에 대한 무관심은 앞으로 선거일정을 조정하는데 하나의 시준점을 삼아야 할 것이다.

육상경기 선수들의 체격과 운동능력 특성 분석

김만호,윤양진 釜山大學校 附設 體育科學硏究所 1997 體育科學硏究所 論文集 Vol.13 No.-

The purpose of this study was to analyse the characteristics of physique and physical fitness and to investigate the effects of athlete's body conposition and physical fitness to athletic performance of sprinters, middle and long distance runners, jumpers and throwers group with 160 track and field athletes of Boy's and Girl's middle and high school in Pusan metropolitan city. In this study 7 factors in body conposition, 9 factors in physical fitness and 16 factors in were measured and analyzed. The results of the study were as follows; 1. The characteristics of the body conposition factors 1) In Boy's middle school throwers group was the biggest and middle and long distance runners group was the smallest in each factors. Throwers group was the biggest in girth bulk among all groups and smaller than jumpers group in standing height in Girl's middle school. 2) In Boy's hight school jumpers grour in length factors and throwers group was bigger in girth and bulk than other groups. Throwers group was the biggest and middle and long distance runners group was the smallest in each factors in Girl's high school. 2. The characteristics of the physical factors 1) In Boy's middle school throwers group was higher in muscular strength agility and flexibility, sprinters group in muscular strength and power, and middle and long distance runners group in balance than other groups. Throwers group was higher in muscular strength and balance, and middle and long distance runners group was the lowest in muscular strength and power than other groups in Girl's middle school. 2) In Boy's high school throwers group was higher in muscular strength, sprinters group in power, flexibility and balance, and middle and long distance runners group in balance, but they were the lowest in other factors. Throwers group was higher in muscular strength, jumpers group in power and balance than other group's in Girl's high school.

토양 미생물인 Streptomyces tubercidicus에서 분리한 GTPcyclohydrolase Ⅰ 저해제

한지만,김시욱,이인화,박열,정혜광,윤성명,유진철 조선대학교 약학연구소 1998 藥學硏究誌 Vol.19 No.1

GTP cyclohydrolase I (EC 3.5.4.16) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphates and formic acid. and thus performs the first committing step in the biosynthesis of the pteridine moiety of folk acid in microorganisms and of tetrahydrobiopterin in higher animals. GTP cyclohydrolase I isolated from Streptomyces tubercidicus was inhibited by DL-6-methyl-5,6,7,8-tetrahydropterin and xanthopterin, and was not inhibited by tetrahydrofolic acid, pterin, pterin-6-carboxylic acid, biopterin, neopterin, ribofravin. These results suggest that bacterial GTP cyclohydrolase I may be regulated by its metaboilic end product.