한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

患者에서 分離된 포도구균이 分泌하는 β-lactamase의 性狀에 關한 硏究

朴粧緖,朴鼎圭,崔大卿 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.1

This study was carried out for the purpose of investigating the β-lactamase producing rates using acidimetric assay and disc method. Also, the author evaluated the drug resistance of ,β-lactamase producing staphylocci isolated from 34 patients in Chungnam National University Hospital and 25 medical students in Chungnam National University by antibiotic susceptibility test. The author sconducted the survey from January to June 1985. The results obtained were as follows: 1. Out of the 34 specimens from patients, Staphylococcus aureus isolated from pus and throat were 58.8% and 17.6%, respectively. 2. The β-lactamase producing rates of staphylococci isolated from patients and control groups using acidimetric assay after 1 year were 88. 2% and 84. 0%, respectively. 3. In the disc method and acidimetric assay, the (β-lactamase producing rates of staphylococci isolated from patients and control groups were 91.2%, 88.2% and 88.0%, 84. 0%, respectively. 4. The rates of resistance for penicillin among p-lactamase producing strains of staphylococci isolated from patients and control groups were 91.2% and 60.0%, respectively. 5. Out of the β-lactamase producing staphylococci isolated from patients and control groups, 88. 2% and 56. 0% were resistant to penicillin but sensitive to cephalothin.

여드름양 발진에서의 말라쎄지아 포자 검출 빈도에 관한 연구

박장규,이웅재,김연수,서영준,김경호,이증훈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

Steroid acne and pityrosporum folliculitis have similar clinical manifestations. So it was not casy to do differential diagnosis of these two diseases. We have tried to find out the different points between these diseases in clinical characteristics, positive rate of the malassezia spores, and their response to antifungal agents. We studied 21 patients with acneiform eruptions which were distinct from acne vulgaris. Patients were divided into two groups by steroid treatment history. Among 21 patients, 6 were administered steroid just before eruption and 15 were free from steroid within 6 months. We have examined malassezia spores with 10% KOH/Parker blue black ink mount from papules, pustules and comedones according to the patients skin lesions. The malassezia spores detected in 5 paticnts(83.3%) in the former and 9 patients(60%) in the latter. In malassezia folliculitis, the frequency of which showed above the (3+) score of malassezia spore under microscopy was higher than in steroid acne. Mean duration of the disease was 70.4 weeks in latter group, which was longer than 5.2 weeks of the former group. And there were some differences between two groups in the distribution of the lesions. Mean treatment duration was same in two groups (4 wks, 3.5 wks). Steroid acne patients would be treated better with antifungal agents than with acne regimens.

자극성 물질이 첩포시험 결과에 미치는 영향에 대한 연구

박장규,이우재,김경훈,서기범,이증훈 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

We studied the effects of irritants on the positive patch test sites in 6 volunteers. We firstly performed the patch test with 2, 4, 6, 8, 10% sodium lauryl sulfate on the back of 22 volunteers. Allergens (thimerosal, mercury ammonium chloride) were applied in duplicate, and 24 hours later they were removed and sodium lauryl sulfate was applied for a further 24hours to one set of patches. Response of allergen alone were measured at 24 hours, 48 hours, 72 hours, 120hours, 140hours and the degree of inflammation of the other site(allergen + irritant) was graded 30 minutes, 24, 48 and 72 hours later according to International Contact Dermatitis Research Group. The results were as follows 1. Twenty volunteers(90.9%) showed irritation sign on the patch sites with 6% sodium lauryl sulfate. 2. In the results of patch test in 6 cases with positive allergen sites, 5 cases showed the similar results with those of previous patch test (reproducibility = 83 %) 3. When we assessed the patch test results according to ICDRG, the results of patch tests after application with irritants on previous positive allergen slites did not show stronger responses than those of positive allergen alone 4. The results of patch test after application with irritants on previous negative allergen did not show erythema. It seems that the effect irritant application of lower concentration than irritant dose not influence the response to the allergen concentration than to cause erythema, on the response of allergen

사마귀의 임상적 고찰

박장규 충남대학교 의과대학 지역사회의학연구소 1983 충남의대잡지 Vol.10 No.2

Warts are the most common viral infection of the skin. Most dermatologists believe that the frequency of warts is increasing. In spite of this commonness and increasing frequency, there is no clear information about warts of koreans. This paper attempts to clarify the epidermiolgical features and behaviour of warts. 1. The sex ration of wart patients was same. 2. The peak age group of wart patients was from 15 years to 24 and within that age there were 48.3% of verruca plana patients, 60.6% of veruca vulgaris patients, and 42.1% of condyloma accuminata patients. 3. Of 112 wart patiens 53.6% had verruca plana, 29.5% verruca vulgaris, and 16.9% condyloma accuminata. 4. Of the wart patients in this series, 60% of verruca plana patients, 37% of verruca vulgaris patients, and 100% of condyloma accuminata patients had the duration of disease less than 1 year at the first visit at out patient department of dermatology. 5. The predilection site of verruca plana is face(90%), verruca vulgaris is the dorsum of hand(69.7%), and condyloma accuminata is sex organ, penis or vagina(42.1%). 6. When the wart patients were compared to the total number and new patients of dermatologic department in each year, the frequency of the wart patients did not increase from 1977 to 1981.

접촉성 피부염 환자와 정상인의 첩포검사에 관한 연구

박장규,성열훈,성범진 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.2

Numerous studies on epidemiological aspects of contact dermatitis due to various causative antigens have been reported n recent year in Korea. However, degree of sensitization in healthy persons was not reported till now in Korea. We have performed the patch test on patients with contact dermatitis and healthy persons. The study results were as follows; 1. Percent of positive reaction in patients with contact dermatitis was 45.9%. The common allergens of positive reactions were nickel sulfate(21.6%), potassium dichromate (10.8%), neomycin sulfate (8.1%), Balsam of Peru (8.1%), mercuric chloride, ammoniated (5.4%), p-phenylenediamine(5.4%), cinnamic alcohol(5.4%), ethylenediamine dihydrochloride (2.7%), formaldehyde(2.7%), wool wax alcohol(2.7%), thimerosal (2.7%), mercaptobenzothiazole(2.7%), imidazolidinyl urea(2.7%) in order of frequency. 2. Percent of positive reaction in healthy persons was 10.3% and the common allergens were mercuric chloride, ammoniated(5.2%), nickel sulfate(3.1%), cinnamic alcohol(2.1%), ethylenediamine dihydrochloride(1.0%), formaldehyde(1.0%), epoxy resin(1.0%), in order of frequency. We conclude that allergens associated with metals and drugs seem to be the dominant causes of contact dermatitis and healthy persons.

백반증의 PUVA치료반응에 관한 연구(제1보)

박장규,성열훈,성범진,김영호,이증훈 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

The authors evaluated response to PUVA therapy in 44 vitiligo petients who did'nt show the spontaneous re-pigmentation. In the responded group to PUVA therapy after systemic administration of 8-methoxy psoralen, average MPD of female patients was 3.4 times higher than males, interestingly. Number of irradiation of UVA was similar between male and female, but total doses of female patients group were about 2 times than males till the first re-pigmented spots were noted. The response to PUVA therapy was quite different according to duration of disease and site of lesion. Therefore, we suppose that it is necessary to consider sex of patient, duration of disease, location of vitiligo before making a plan of PUVA therapy.

대상포진에 대한 Isoprinosine의 치료에 대한 임상연구

박장규,한효수 충남대학교 의과대학 지역사회의학연구소 1984 충남의대잡지 Vol.11 No.2

In order to estimate the effectiveness of isoprinosine on herpes zoster, the authors selected 83 patients with herpes zoster from October, 1980 to January, 1984 at Chungnam National University Hospital. Among the patients, 54 patients participated in the drug trial. No substantial differences between the groups treated with isoprinosine and symptomatic therapy could be seen in the duration of treatment.

국민학교 아동의 체력실태 : 형태와 운동능력 중심으로 Based on Physique and Motor Fitness

朴庄平,李光宰,盧成圭,洪寬伊,李京濟 江原大學校附設體力硏究所 1980 江原大學校附設體育科學硏究所論文集 Vol.- No.5

알레르기성질환의 기인항원에 관한 연구

박장규,구자경 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.2

To fine out the offending allergens in Chungnam province, we performed skin test with 196 diagnostic allergens (Bencard®) in 83 cases of allergic rhinitis and 26 cases of chronic urticaria from August 1982 to August 1986 at the dermatologic OPD. of Chungnam National University Hospital. The results were: 1. The positive reaction of the skin test to the diagnostic allergens in the cases of the allergic rhinitis and chronic urticaria were 91.6% and 80.8%, respectively. 2. In allergic rhinitis, 25% showed the positive reaction to single allergen and 66% to compound allergens and the offending allergens were D. farinae (56.0%), D. pteronyssinus(43.4%), house dust (35.5%), cat fur (30.3%), hay dust (22.3%) in order. 3. In chronic urticaria, 23% showed the positive reaction to single allergen and 58% to compound allergens and the offending allergens were D. farinae (33.3%), mosquito (33.3%), D. pteronyssinus (24%), mixed threshings (24%), maize pollen (24%) in order.