CFRP 복합재 적층판의 파괴메카니즘에 관한 연구

이권범,박환규,홍석주,김기형 조선대학교 동력자원연구소 1996 動力資源硏究所誌 Vol.18 No.1

In this study, when CFRP lamimates are subjected to static loading by the indentation of steel ball to examine a failure mechanism of lamimates, the fracture surface of interlaminar delamination generated at interfaces is investigated by the scanning electron microscopy (SEM). When orthotropic CFRP laimates stacked with two interface are subjected to static loading, interlaminar delaminations extend from the loading side to delamination edge even at any interface, and the fracture surface fo interlaminar delamination generated at two interfaces is symmertrically formed. In the CFRP laminates, the fracture mechanism sppears mainly to be the mixed mode(modes Ⅰ+Ⅱ), and the ratio of mixed mode varies partially. After the fracture initiates at the interface near the loading side with mode Ⅰ, the mixed mode gradually developes, but the total surface at the opposite plane to the loading side fractures with the mixed mode(modes Ⅰ+Ⅱ). While transverse cracks are generated, the direction of shear stresses reverses itself ar the delaminated surface, clarified by the hackle direction of fracture surface.

다랑 토혈 후 발생한 뇌경색으로 인하여 간질중첩증을 보인 간성 뇌중 1예

오형근,정두신,이경복,양광익,박형국 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.1

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삼차신경 감각핵의 세포활성도와 Substance P 유리에 대한 Capsaicin, Paradol 및 Shogaol의 전통작용기전에 관한 연구 : Ⅰ. 유해자극에 의한 개구반사와 삼차신경 척수감각핵의 Substance P에 미치는 영향 Ⅰ. EFFECTS ON JAW OPENING REFLEX BY NOXIOUS STIMULUS AND RELEASE OF SUBSTANCE P

이종흔,김중수,송형근,박수정,함진숙 대한구강생물학회 1990 International Journal of Oral Biology Vol.14 No.1

The purpose of this investigation was to determine the relative analgesic effectiveness of paradol and shogaol compared with capsaicin, and effects of capsaicinoids on substance P of trigeminal spinal sensory nucleus. Under anesthesia, anterior belly of digastric muscle was exposed and a pair of electrodes was inserted to record the electromyograms. Noxious electrical stimulus was applied to oral mucosa around the mental foramen. Inferior alveolar nerves (IAN) and saphenous nerves were carefully exposed for application of vehicle and drugs to evaluate the effects on digastric EMG (dEMG) and neural conduction, and caudal part of brainstem was exposed to determine the substance P. Vehicle and 1.5% of capsaicin, paradol and shogaol were applied to IAN and saphenous nerves for 30 minutes, respectively. EMG_s of digastric muscle evoked by noxious electrical stimulus were recorded before application of drugs or vehicle, immediately after removal and washing of drugs and at 30 minutes after washing. To examine the effects of the peripheral stimulation on the action potential, stimulating electrodes were placed on the peripheral side of drugs application site and recording electrodes were on the proximal side. Substance P of trigeminal spinal sensory nucleus was collected by push-pull perfusion technique and determined by radioimmunoassay. Capsaicin application on IAN could not influence on dEMG, but paradol and shogaol decrease the amplitude of dEMG. Capsaicin applied locally to nerve decreased amplitude and conduction velocity of only C-fiber, while paradol and shogaol inhibited the neural conduction of C-fiber and Aδ-fiber. Substance P in the trigeminal spinal nucleus was reduced by capsaicin but not by paradol and shogaol.

플라즈마 표지소자의 제작

이상윤,라병욱,박동수,황인헌,이덕동,신영남,박성배,이동욱,박용석,박형근,손상호,권태근,채경락,정경득 慶北大學校 自然科學大學 1986 自然科學論文集 Vol.4 No.-

An Ac-type Plasma Display Panel (PDP) operating with Ne-Ar(0.1%) Penning mixture gas is fabicated. The characterics of the panel with electrodes covered with thin and thick dielectric layers are studied. The brightness of the Neon-orange light emitted by the panel measured as function of applied voltage and frequency. As an application, a graphic display system equipped with PDP showing still and moving pictures is made.

족삼리의 전기침 자극에 대한 개구반사 크기의 변화

이상호,나창수,송형근,서영아 大韓小兒齒科學會 1998 大韓小兒齒科學會誌 Vol.25 No.4

The purpose of this study was to investigate the effect of various electroacupuncture duration induced by acupuncture point-Zusanli(S36) electrical stimulation on inhibition of amplitude of digastric electromyogram (dEMG)evoked by noxious electrical stimuli around the mental foramen. <Experiments were conducted on adult rats (SD) were anesthetizde with> intraperitoneal sodium pentobarbital in an initial dose of 50mg/kg and maintenance doses of 4.5mg/kg/h were given through a cannula in the femoral vein using a constant infusion pump. A pair of stimulating electrodes were inserted for noxious stimuli around the mental foramen. An irritant electronic stimuli pulse (0.2 Hz,0.1 ms duration) was produced with an intensity of about 1.5-2 times threshold for evoking the dEMG. The anterior belly of the digastric muscle was exposed and a pair of 0.1mm wire electrodes were inserted for dEMG recording. Acupuncture point stimulation on Zusanli (2 Hz, 250㎲, biphasic pulse. 2 V) was delivered by Dental Electronic Anesthesia (3M,U.S.A). For periods of electronic stimulation of 10, 20, and 30min, the amplitudes of dEMG were measured on the oscilloscope and on the monitor connected to the amplifier. The following results were obtained: The dEMG was decreased to 73.4% of that in the control set after 10 min electroacupunture stimulation (Group Ⅰ): The dEMG was decreased to 77.1%(10min), 54.0% (20min)of that in the control set after 20minutes of electroacurunture stimulation (Group Ⅱ). The dEMG was decreased to 73.7% (10min), 61.9%(20min), 76.2%(30min) of that in the control set after 30 min of electroacupunture stimulation (Group Ⅲ). From these results, it may be that in the electroacupuncture stimulation on the Zusnali resulted in a reduction of amplitude of daEMG and that the most effective electroacupuncutre stimulation period was 20min.

장상피화생과 Helicobactor pylori와의 상관 관계에 관한 연구

이복희,김대수,이현숙,진영주,윤세진,송형근,성노현,정현용,이동호 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

In 1965 Lauren divided advanced gastric carcinoma into two main types-namely, "intestinal" and "diffuse" type carcinoma, which differ not only morphologically but also in their clinical and epidemiological characteristics. Moreover, a different histogenetic process has been postulated by many authors that intestinal type gastric carcinoma might arise from areas with intestinal metaplasia. Since Warren and Marshall reported the presence of Helicobacter pylori in the stomach in 1983, strong evidence has been obtained that there is a close relationship between Helicobacter pylori and chronic gastritis, atrophic gastritis, intestinal metaplasia, and intestinal type gastric carcinoma. To study the relationship between intestinal metaplasia and Helicobacter pylori infection, we performed gastroscopic biopsies and CLO tests taken from patients with epigastric pain. Only 87 patients with macroscopically suspected antral gastritis were included. The prevalence of intestinal metaplasia in gastric antral biopsies increased from 33.3% in the age group<30 years to 63.6% in the age group 60 years. When all patients were divided into two age groups-namely, (i)<50 years(n=41) and (ii)≥ 50 years(n-=46), intestinal metaplasia was found significantly more often in patients ≥ 50 years. ((i) 39.2%, (ii) 54.3%, p<0.0001). The prevalence of Helicobacter pylori in gastric antral biopsies decreased from 66.7% in the age group<30 years to 62.5%, in the age group in the age group 50 to 59 years. When all patients were divided into the same two age groups-namely(i)<50 years and (ii)≥50 years, the prevalence of Helicobacter pylori did not differ between two groups in a statistically significant way. The mean age of intestinal metaplasia positive patients who were also Helicobacter pylori positive was 48±11.0(mean±S.D.)years, whereas the mean age of intestinal metaplasia positive patients who were Helicobacter pylori negative was 52±9.7(mean±S.D.)years. In conclusion. although our data do not prove a causal relationship between Helicobacter pylori infection and the histogenesis of intestinal metaplasia, we suggest that Helicobacter pylori plays an important role in the development of intestinal metaplasia in the gastric mucosa. Whether Helicobacter pylori has to be present at all times during this process or is only necessary as a 'trigger', needs further research.

실험 방광암 모델에 있어서 Proliferating Cell Nuclear Antigen이 발현되는 세포들의 색상-화상 분석

이현무,이태수,김원재,차은종,송형근 충북대학교 의과대학 충북대학교 의학연구소 1993 忠北醫大學術誌 Vol.3 No.1

Proliferating cell nuclear antigen(PCNA)에 대한 단클론성 항체에 의해 면역조직화학적으로 염색된 세포들의 평가에 있어서 색상-화상 분석의 역할을 살펴보고자 하였다. BBN 투여 기간에 따라 Fisher 344 백서 방광에 정상 상피로부터 단순 과증식, 결절성 혹은 유두상 과증식 및 표재성 방광암에 이르는 순차적인 병리세포학적 변화가 발생함을 관찰한 후, 이를 색상-화상 분석과 육안적 분석을 통해 PCNA에 대한 평균 labeling index를 구한 결과 두가지 방법에서 모두 각 병변 사이에 통계적으로 유의한 차이를 보였으나, 색상-화상 분석을 이용하여 구한 평균 labeling index의 변이계수가 육안적 분석을 이용하여 구한 평균 labeling index의 변이계수에 비해 전 병변에 대하여 낮게 나타나, 종양화과정이 진행함에 따라 PCNA에 대한 평균 labeling index가 증가하고 평균 labeling index가 높을 수록 증식도가 더 큼을 나타낸다는 결과를 얻었으며, 색상-화상 분석을 이용하여 얻은 결과가 육안적 분석을 이용하여 얻은 결과보다 신뢰도가 더 높은 것으로 나타났다. 이와같은 면역조직화학염색에 대한 색상-화상 분석을 통한 세포역동학적 연구는 정량화 및 재현성의 향상을 통해 면역조직화학염색의 평가에 있어 보다 신뢰도가 높은 정보를 제공하여줄 것이며, 이를 통해 방광종양의 증식도 및 악성도를 예측하는데 중요한 역할을 할 것으로 생각된다. A study was carried out to define the role of color-image analysis in evaluation of immunohistochemically labeled cells using anti-PCNA/cyclin monoclonal antibody. Sequential cellular changes(normal, simple hyperplasia, nodular or papillary hyperplasia, and transitional cell carcinoma-Ta, T1) were observed in Fisher 344 rat urinary bladder depending on the duration of BBN administration. The mean PCNA labeling index obtained by color-image analysis and visual analysis in normal, simple hyperplasia, nodular or papillary hyperplasia and bladder tumor showed statistically significant difference in each histological group. But coefficients of variation of mean PCNA labeling index obtained by color-image analysis were lower than those using visual analysis in all lesions. Higher PCNA labeling indices indicated greater biological malignant potential, and mean labeling index in each histological group obtained by both color-image and visual analysis progressively increased with tumorigenesis, but the coefficient of variation with color-image analysis was lower than that with visual analysis in general, therefore, the evaluation of labeling indices obtained using color-image analysis was more reliable than that obtained using visual analysis. The data suggest that cell kinetic evaluation using color-image analysis may provide more reliable information to evaluate immunohistochemical staining in terms of quantitation and reproducibility and play an important role in predicting proliferative activity and malignant potential for bladder tumor.

상완골 간부 골절 불유합의 금속판과 자가골 이식에 의한 치료 결과

이광현,이성필,김형종,이봉근,김주학 대한골절학회 2004 대한골절학회지 Vol.17 No.2

새로운 은닉 서명 방식에 관한 연구

오형근,이임영 순천향대학교 부설 산업기술연구소 1999 순천향 산업기술연구소논문집 Vol.5 No.1

An important requirement for Electronic Cash protocol is a anonymity fo the user. Electronic cash structured by a digital stream use blind signature, a special signature scheme, to get bank's signature guaranteeing user's privacy. The concept of blind signature scheme was introduced by Chaum and its numerous variants are proposed. In this paper we propose a new blind signature drive from a variation of the KCDSA. It is a blind KCDSA signature scheme with message recovery and useful in electronic cash protocols. Also its security equal the KCDSA.

척수 손상으로 발생된 신경인성 방광 환자의 요역동학 검사상 고위험 인자 분석

김형지,송인호,이근호 단국대학교 1998 論文集 Vol.32 No.-

Purpose : Spinal cord injury is one of the most devastating states of infirmity encountered by today's health care professional. Historically, urologic complication have been the major source of morbidity and mortality among spinal cord injury patients. The main objective in management of neuropathic bladder is the preservation of renal function because the renal deterioration is the most serious problem of neuropathic bladder. We investigated risk factors for renal dysfunction in neuropathic bladder from spinal cord injury. Materials and methods : A total 36 spinal cord injury patients of neuropathic bladder with voiding dysfunction was evaluated by urodynamic study and we analyzed the risk factors associated with upper urinary tract deterioration. Results : In cases of spinal cord injury, detrusor external sphincter dyssynergia and high detrusor pressure were risk factors of upper tract deterioration. Conclusions : In management of neuropathic bladder, the abnormalities of individual lesion-specific urodynamic parameters(detrusor sphincter dyssynergia, low compliance, high detrusor pressure) should be factored into the assessment of upper urinary tract deterioration.