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      • 대학생의 취업스트레스와 자아존중감, 자아효능감, 외모관리행동의 관계

        김보라,김유진,김지희,노혜진,오승희,홍지혜,황윤희,박선아 水原大學校 2016 論文集 Vol.30 No.-

        Purpose: Many university students are under a lot of job-seeking stress because the employment rate is low. This study sought to determine the relationship between job-seeking stress, self esteem, self efficacy and appearance management behavior amongst university students focusing on nursing. Methods: This descriptive correlational study evaluated the relationships between job-seeking stress, self esteem, self efficacy and appearance management behavior of 340 university students was conducted between September 1 and October 5, 2015. Results: The correlational analysis between job-seeking stress, self esteem, self efficacy and appearance management behavior revealed a negative correlation between job-seeking stress, self esteem and self efficacy and a positive correlation between job-seeking stress and appearance management behavior. In addition, age also correlated with self esteem, self efficacy and appearance management behavior. Conclusion: Stress correlated with self esteem and self efficacy and appearance management behavior. Therefore job-seeking stress may be reduced through not only self esteem and self efficacy enhancement programs but also management according to age.

      • KCI등재

        유색미에 관한 연구 : Ⅲ. 유색미 유망계통에 대한 주요 생육 특성

        김광수,최윤표,김선택,최현구,정종태,김보경,유지홍,이희봉 충남대학교 농업과학연구소 2007 농업과학연구 Vol.34 No.2

        국내외 유색미 수집종을 돌연변이원에 의해 유기된 우수 계통과 수집종간 상호교배에 의해 선발된 CNU 20계통을 파종하여 얻어진 주요 작물학적 특성을 살펴보면 다음과 같다. 1. 간장은 유색 메벼인 CNU126 계통이 대조품종인 동진벼와 같이 가장 컸고 메성인 CNU 128계통에서 가장 작았다. 2. 주당 분얼수는 CNU3, CNU50. CNU56, CNU112 계통에서 가장 많았고 대조품종과 CNU 128 계통에서 10개 미만으로 가장 적게 나타났다. 3. 수장은 육성 계통 중 CNU88 계통에서 가장 길었으나 대조구보다 짧고, 육성계통 중에서는 CNU 126 계통이 가장 짧았다. 4. 주당 영화수는 대조구인 동진벼보다 CNU50 계통에서 2배 이상 많았고, CNU158 계통에서 가장 적게 나타났다. 5. 천립중은 CNU113 계통에서 30g이상으로 대조구와 같이 가장 무거웠고, CNU128 계통에서 20g으로 가장 적었다. 6. 주당 수량은 대조구의 26.6g에 비해 CNU50, CNU112 계통에서 두배정도 높았고, CNU128, CNU158, CNU200 계통에서 가장 낮게 타나났다. Aims of this study were carried out to develop the useful lines induced from mutation and pedigree breeding methods among the collected genetic resources from national and domestic areas. In this study, Stem height of CNU126 line and check among them were high, while CNU128 was lower than other lines. Spiklet length of CNU88 was longer, but that of CNU126 was shorter than check. Number of spiklets per plant of CNU50 among lines have twice time than check. 1,000 grains weight of CNU113 was higher than check. In yield per plant, CNU50 and CNU112 were higher than check, Dongjinbyeo.

      • SCIESCOPUSKCI등재
      • KCI등재

        Realization of Public Interest under Compulsory Licensing System of Drug Patents in China

        Bo, Yu-Hong 원광대학교 법학연구소 2019 의생명과학과 법 Vol.21 No.-

        의생명윤리와 관련하여 의약품에 대한 특허강제허가제도의 도입은 세계적으 로 관심을 가지는 과제 중 하나이다. 이에 대하여 현재 중국의 입법에 있어 관 련 규정이 있다고는 하지만, 대부분이 원칙적이고 추상적인 규정에 지나지 않아 실무 상 구체적 적용에 있어 어려움이 있다. 의약품 특허강제허가제도는 공공의 건강권과 제약회사의 개인이익 간 충돌에 대한 형평성을 조율하기 위한 목적이 다. 여기에서 충돌의 본질은 지식재산권의 공권속성과 사권속성 간 어떤 것을 우선으로 할 것인지에 대한 일종의 시소게임(seesaw game)으로, 공권속성과 사권속성 간 어떤 동태적인 형평성을 처리하는 과정으로 보아야 한다. 또한, 의료행위에 사용되는 의약품에 대한 행정적 강제행위가 생명과 건강을 중심으로 한 인간중심적 가치를 우선으로 하여야 하는지, 사회발전을 위한 이익 에 중점을 두어야 하는지의 문제에 있어 의료법 등 관련 법률에서 어떻게 입법 적으로 조율할 것인지도 문제로 된다. 구체적으로는 입법에 있어 의약품의 특허 강제허가와 관련한 조문 등에서 ‘합리적’ 가치실현을 담아내야 하며, 의약품 특 허강제허가의 다원적 경로를 확보하여 신중하게 의약품 특허강제허가제도를 법 률적으로 운영하여야 할 것이다. 이를 통해 의약품의 특허관련 제도가 인간중심 적 가치와 공공이익을 모두 실현할 수 있을 것이다. 본 연구의 핵심은 공공이익이라는 목적의 실현에서 이러한 동태적 형평을 입 법적으로 어떻게 처리하는 것인지이다. 구체적으로는 중국의 사법실무의 검토를 통하여 현재 의약품 특허강제허가제도에 존재하는 문제를 검토한다. 또한, 외국 의 관련 규정을 소개하여 중국의 입법에 어떠한 시사점이 있는지를 분석한다. 이를 통해 의약품 특허강제허가제도에 대한 중국과 외국 제도 간 인간중심의 가치와 사회공평발전가치, 즉, 의료행위를 통한 인간생명 및 건강의 우선과 사 회발전에 있어서의 이익우선에 있어 그 법적가치에 대한 중국과 외국 간의 간 격을 줄일 수 있는 방안을 모색한다. The Compulsory Licensing System of Drug Patents is a global issue. As far as China's specific situation is concerned, although there are relevant provisions in the legislation, mostly principled expression which makes the specific operations an overhead state in practice. As far as the system itself is concerned, its purpose is to better balance the conflict between public health rights and the private interest of pharmaceutical companies. The conflict is essentially a game between the public rights and private rights of intellectual property. Dealing with the interaction between public rights and private rights is a dynamic equilibrium process. How to deal with the process of dynamic balance is the key to this paper. On the one hand, this paper clarifies the current dilemma of the compulsory licensing system of drug patents through the review of China's relevant judicial practice; on the other hand, it reflects on the status quo of China's legislation through the introduction of the relevant provisions of other countries. Hence, the discussion of the above two aspects is very close to the analysis of the legal value of the system itself, which is manifested in two levels: humanistic care value and value for social fair development. In order to achieve the above values, it is necessary to balance the conflict between public health and private interest. Specifically, which is mainly reflected by the “reasonable” expression in the patent compulsory license provisions. The realization of the public interest depends on the diversification of Compulsory Licensing System of Drug Patents and the prudent use of these systems.

      • KCI등재

        한국토종닭 3원 교잡종의 부화 및 육성 능력 (pp.399-404)

        강보석(Bo-Seok Kang),홍의철(Eui-Chul Hong),김학규(Hak-Kyu Kim),유동조(Dong-Jo Yu),박미나(Mi-Na Park),서보영(Bo-Young Seo),추효준(Hyo-Jun Choo),나승환(Seung-Hwan Na),서옥석(Ok-Suk Seo),황보종(Jong Hwang bo) 韓國家禽學會 2010 韓國家禽學會誌 Vol.37 No.4

        본 시험은 한국토종닭 3원 교잡종의 부화 및 육성 능력을 보고자 수행하였다. 공시계는 국립축산과학원에서 생산된 종란을 인수하여 부화시킨 3원 교잡종 병아리 암컷이다. 4가지 교배 조합으로 생산된 360수의 암평아리들을 3반복으로 반복당 30수씩 완전 임의배치하였다. 4개의 교배 조합은 A) 토착겸용종 C계통×재래종 Y계통×토착겸용종 C계통, B) 토착겸용종 C계통×재래종 L계통×토착겸용종 C계통, C) 토착 겸용종 C계통×재래종 G계통×토착겸용종 C계통, D) 토착겸 용종 C계통×재래종 W계통×토착겸용종 C계통이다. 수정률은 A, B, C 및 D에서 각각 89.8, 91.2, 92.4 및 92.8%였으며, 부화율은 각 계통에서 69.8, 70.7, 75.5 및 77.4%였다. 육성률은 계통간 유의적인 차이가 없었다(P>0.05). 20주령 체중은 B계통에서 높게 나타났으며(P<0.05), 0~20주령까지의 사료 요구율은 4계통에서 유의적인 차이는 없었다(P>0.05). 이런 결과들은 한국토종닭 3원 교잡종의 부화 및 육성 성적에 대한 기초적인 자료로서 이용될 것이라 사료된다. This work was conducted to evaluate the hatching and growing performance of Korean native chicken (KNC) 3 strains crossbred. A total of 360 female pullets were produced from CY × C (A), CL × C (B), CG × C (C) and CW × C (D) crossbred kept in National Institute of Animal Science, Korea. Hatchability of A, B, C and D were 69.8, 70.7, 75.5 and 77.4%, respectively. Livability were not significantly different by 20 weeks among 4 strains. Body weight B was high compared to other strains at 20 weeks. The feed conversion ratio of 4 strains was no significantly different among strains at 20 weeks. These results suggested the basic data that needed to develope the new strains.

      • Usefulness of Serum Krebs Von Den Lungen-6 as a Diagnostic Marker for Cryptogenic Organizing Pneumonia

        ( Hong-joon Shin ),( Jae-kyeong Lee ),( Hyung-joo Oh ),( Min-seok Kim ),( Bo Gun Kho ),( Ha Young Park ),( Tae-ok Kim ),( Cheol-kyu Park ),( Yong-soo Kwon ),( In-jae Oh ),( Yu-il Kim ),( Sung-chul Lim 대한결핵 및 호흡기학회 2020 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.128 No.-

        Background Cryptogenic organizing pneumonia (COP) is idiopathic interstitial pneumonia characterized on imaging by multifocal ground glass opacities and/or consolidation. COP is similar to bacterial or viral pneumonia in clinical and radiologic features, therefore, it is necessary to differentiate between COP and pneumonia. Krebs von den Lungen-6 (KL-6) has been proposed as a diagnostic biomarker for differentiating interstitial pneumonia. This study was to evaluate the usefulness of serum KL-6 in the diagnosis of COP by comparing serum KL-6 in COP and pneumonia patients. Methods We retrospectively reviewed patients who measured serum KL-6 from January 2020 to July 2020. COP was defined as idiopathic, presence of typical chest CT features, and elevation of lymphocyte in bronchoalveolar lavage fluid and/or pathological findings for COP on transbronchial lung biopsy. Results Total of 47 patients were enrolled in the study, 19 for COP and 28 for pneumonia, respectively. Eleven patients were diagnosed with COP by transbronchial lung biopsy. The mean age was 71.0 in COP and 68.7 in pneumonia. Female was predominant in COP (63.2% vs. 28.6%; P = 0.019). The mean values for white blood cells (WBC) and C-reactive protein (CRP) were significantly higher in pneumonia than in COP (WBC: 12896 vs. 7721/uL; P = 0.004, CRP: 12.6 vs. 3.1 mg/dL; P < 0.000). The mean value for serum KL-6 was significantly higher in COP than in pneumonia (1047 vs. 436 U/mL; P = 0.010). Receiver operating characteristic curve for diagnosis of COP showed the area under the curve of serum KL-6 was 0.812. When the cut-off value of serum KL-6 was 450 U/mL, sensitivity was 73.7% and specificity was 67.9%, respectively. Conclusion: These Results suggest that serum KL-6 is a useful diagnostic marker for COP.

      • KCI등재

        The microRNA expression profiles of mouse mesenchymal stem cell during chondrogenic differentiation

        ( Bo Yang ),( Hong Feng Guo ),( Yu Lan Zhang ),( Shi Wu Dong ),( Da Jun Ying ) 생화학분자생물학회(구 한국생화학분자생물학회) 2011 BMB Reports Vol.44 No.1

        MicroRNAs are potential key regulators in mesenchymal stem cells chondrogenic differentiation. However, there were few reports about the accurate effects of miRNAs on chondrogenic differentiation. To investigate the mechanisms of miRNAs-mediated regulation during the process, we performed miRNAs microarray in MSCs at four different stages of TGF-β3-induced chondrogenic differentiation. We observed that eight miRNAs were significantly up-regulated and five miRNAs were down- regulated. Interestingly, we found two miRNAs clusters, miR-143/145 and miR-132/212, kept on down-regulation in the process. Using bioinformatics approaches, we analyzed the target genes of these differentially expressed miRNAs and found a series of them correlated with the process of chondrogenesis. Furthermore, the qPCR results showed that the up-regulated (or down-regulated) expression of miRNAs were inversely associated with the expression of predicted target genes. Our results first revealed the expression profiles of miRNAs in chondrogenic differentiation of MSCs and provided a new insight on complicated regulation mechanisms of chondrogenesis. [BMB reports 2011; 44(1): 28-33]

      • KCI등재

        Identification of pollutant sources using water quality and stable isotope ratios of inflow tributaries in the lower reaches of the Han-River

        Hong, Jung-Ki,Lee, Bo-Mi,Son, Ju Yeon,Park, Jin-Rak,Lee, Sung Hye,Kim, Kap-Soon,Yu, Soon-Ju,Noh, Hye-ran The Korean Society of Analytical Science 2019 분석과학 Vol.32 No.2

        Despite the expansion of sewage treatment facilities to reduce pollutants in the tributaries of the Han River, water pollution accidents such as fish deaths continue to frequently occur. The purpose of this study was to identify the pollutant sources using water quality and stable isotope ratio (${\delta}^{15}N$, ${\delta}^{13}C$, ${\delta}^{15}N-NH_4$, ${\delta}^{15}N-NO_3$) analysis results in the three inflow tributaries (Gulpocheon (GP), Anyangcheon (AY) and Sincheon (SC)) of the Han River. Water quality was analyzed in June and October from 2013 to 2017, and the results showed that the concentrations of nutrients, such as T-N, $NO_3-N$, and T-P, were increased at GP4, AY3, SC3, and SC4, which lie downstream of sewage treatment facilities. The results of ${\delta}^{15}N$ for June 2017 indicated that the source of nitrogen was sewage or livestock excreta at GP4 and SC4, and organic fertilizers at AY3 and SC3. ${\delta}^{15}N-NO_3$ results suggested that the source of nitrogen was related to organic sewage, livestock or manure at GP4, AY3 and SC4. Therefore, GP4 and SC4 were more influenced by effluent from sewage treatment facilities than by their tributaries, AY3 and SC3 were considered to be influenced more by their tributary than effluent from sewage treatment facilities. With the results of this study, the source of contamination (sewage treatment facility effluent) of river inflow downstream of Han River could be confirmed using water quality and stable isotope ratio.

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