8년간(1992~1999) 산업안전보건연구원에 의뢰된 직업병 심의 사례 분석

강성규,김규상,김양호,최정근,안연순,진영우,최병순,양정선,김은아,채창호,최용휴,김대성,박정선,정호근 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

Objectives : Pneumoconisis and noise-induced hearing loss (NIHL) have been reported as main occupational diseases by the Special Health Examination. The Industrial Accident Compensation Insurance has reported various work-related diseases, however, these two diseases occupied almost a half of compensated cases. Therefore, it was not well known about the status of occupational diseases other than pneumoconiosis, NIHL, and cardio-cerebrovascular accident (CVA). This study was conducted to analyze claimed cases as an occupational disease, that was requested to the Korea Industrial Safety and Health Agency (KOSHA). Methods : The local office of the Korea Labor Welfare Corporation (KLWC) has asked the KOSHA for confirmation of claimed cases as an occupational disease. We analyzed 379 cases requested from KLWC, the Ministry of Labor, employers, unions and occupational health agencies from 1992 to 1999. Results : Male was 80.7 % of the requested cases. Their mean age was 42 years old and 75.5 % of them were more than 35 years old. The requested cases were increased rapidly from 25 cases in 1992 to 108 cases in 1999 and the accept rate was 50.7 %. The majority of requested cases were respiratory diseases(22.4%), cancers(18.5%), Neuropsychiatric problems(14.5%), and musculoskeletal problems(13.5%). The accept rate was high in reproductive, respiratory, musculoskeletal and digestive disorders and low in neuropsychiatric, renal and otologic problems and occupational cancers. 73.6% of them were caused by chemical agents, especially 28.5 % were by organic solvents. 67% of them were clinically confirmed at university hospitals. A half of the cases were from KyongIn area, even the request came from the whole country. Conclusions : A claim was common in workers whose age was over 35 years old and exposure history was over 10 years. The respiratory diseases and neuropsychiatric disorders were still main problems in occupational health and occupational cancers was increasing even though its accept rate was not high yet.

전국 가정의학과 전공의 수련내용

양병국,이행,윤영호,조은연,유태우,허봉렬 大韓家庭醫學會 1993 Korean Journal of Family Medicine Vol.14 No.4-5

청신경종의 크기에 따른 어지러움의 양상 및 전정기능 검사의 특징

정원호,홍성화,조양선,김성민,장병찬,최재연,이승진 대한이비인후과학회 2000 대한이비인후과학회지 두경부외과학 Vol.43 No.1

신장내 국소혈류량 조절에 대한 신교감신경의 영향

양훈모,민영기,김동진,송호연,송윤섭 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

Control of blood pressure is affected by regulation of intrarenal blood flow. Renal sympathetic nerve simulation inhibits pressure-depressor mechanism of kidney. This antidepressor mechanism was known as happening to due to a decrease the blood supply of renal medulla. It is not known whether renal sympathetic nerve innervation of renal medulla is and it affects regulation of medullary blood flow. We tried to measure total renal blood flow(TRBF), cortical blood flow(CBF), papillary blood flow(PBF) by ultrasonic and laser Doppler techniques in Wistar rats during 3 kinds of renal sympathetic nerves stimulation. The simulation orders are tried randomly and each stimulation period is 15 minute. TRBF and CBF decreased at 1 Hz by 2 and 2%, 3Hz by 18 and 15%, 5Hz by 49 and 44%, respectively as similar to each other. But PBF increased by 1% at 1 Hz and 4% at 3 Hz, while it decreased by 4% at 5 Hz. Therefore, it seems superficial renocortical and total renal blood flows are closely regulated by renal sympathetic nerves with increasing vasoconstriction at 5 Hz, onthe other hand while medullary blood flow seems to be under strong local control, tending to offset neurogenic flows restrictions.

췌장염에 의한 가성낭종내에 생긴 가성동맥류 : 1례 보고

오연희,이채경,김승현,이성우,양창현,이정호,이영현 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

만성 췌장염의 합병증으로 생긴 가성동맥류는 드문질환으로, 반복적으로 다량의 출혈을 일으킬 수 있으며, 치료를 하지 않을 경우 사망율이 높기 때문에, 조기 진단과 치료가 필수적이다. 저자들은 38세 남자 환자에서 췌장염의 합병증으로 생긴 가성낭종내에서 발생한 가성동맥류 1예를 경험하였기에 보고하는 바이다. 가성 동맥류의 색혈류도플러상 낭종내에 양방향 흐름의 와류를 볼 수 있었다. Pancreatic Pseudoaneurysm within Pseudocyst from Pancreatitis: 1 Case Department of Diagnostic Radiology and Internal Medicine, College of Medicine,DongGuk University Yeon Hee OH M.D., Chae Kyeong Lee M.D., Seoung Hyeon Kim M.D., Sung Woo Lee M.D., Chang Heon Yang M.D., Jung Ho Lee M.D., Young Hyun Lee M.D. Pseudoaneurysm from pancreatitis is uncommon, but it can cause recurrent and massive hemorrhage. Because of high morbidity and mortality, early detection and treatment of the pseudoaneurysm is needed. We report a case of pseudoaneurysm within pseudocyst from pancreatitis. Color-flow Doppler sonography shows bidirectional flow and turbulent arterial flow, within anechoic mass.

위선암에서 p53, MMP-2 및 TIMP-2의 표출

황호현,김의한,오미혜,조현득,양승하 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

Gastric adenocarcinoma is the most common malignant tumor in Korea. Many oncogens have been found in malignant tumor cells. Among these oncogene, MMP-2 and TIMP-2 show important role in invasivness and metastasis of malignant tumor cells. P53 is regulator of cellular proliferation, and the over expression of p53 relate to malignant transformation and prognosis. To evaluate the expression of MMP-2, TIMP-2, and p53 according to histopathologic features and the relation between these antigens and prognosis in gastric adenocarcinoma, we have performed immune staining, using mouse anti-MMP-2, mouse anti-p53, and mouse anti-TIMP-2 for 91 cases. The results were as follows; 1) The expression rates of MMP-2, TIMP-2, and p53 in gastric adenocacinoma were 58.2%, 57.1%, and 49.5%, respectively. 2) MMP-2 and TIMP-2 in gastric adenocarcinoma showed reverse correlation.(p<0.001) 3) MMP-2 showed more higher expression rates in intesinal type and sell differentiated form of gastric adenocarcinoma, and in cases showing more deeper invasion and metastasis to lymph nodes in advanced carcinoma. 4) TIMP-2 in advanced carcinoma showed more lower expression rates in cases showing more deeper invasion and metastasis to lymph nodes. 5) MMP-2 expression and TIMP-2 non-expression showed more higher frequency in intestinal type of gastric adenocarcinoma and in cases showing more deeper invasion depth in advanced carcinoma. 6) p53 in advanced carcinoma showed more higher expression rates in cases more deeper invasion and metastasis to lymph nodes. Above results indicated that MMP-2 and TIMP-2 in gastric adenocarcinoma shows reverse correlation, and may be show reverse relation according to progression, type, invasion depth, and metastasis to lymph node. The expression of p53 may be related to metastasis to lymph nodes and degree of depth in advanced carcinoma.

편심 압축력을 받는 스테인리스 원형강관 기둥의 곡률형상에 따른 좌굴내력에 관한 실험적 연구

장호주,서성연,양영성 대한건축학회 2005 大韓建築學會論文集 : 構造系 Vol.21 No.3

This study is a series of experimental investigation on the buckling strengths of eccentrically compressed cold formed stainless steel CHS(circular hollow section) columns. The principal parameters in this study are slenderness ratios( λ=30, 50, 70) and magnitude of eccentricity e(0, 2.5, 5.0, 7.5, 10㎝) on the direction of end moment. The direction of end-moment means 3 different bending moment distributions. Objectives this study are to obtain the maximum loads and moments by performing an experimental work and to compare the experimental behaviors with the design standard curves, AIK-LSD and AISC-LRFD, AIJ-LSD, SIJ-ASD curves. The ultimate buckling strengths and bending moments of circular section members are evaluated by a method in accordance with design standard curves. Therefore this paper attempts design standard for the use of these stainless steel columns as structural compression members. The numerically obtained ultimate buckling strengths and bending moments design standard curves of beam columns show a reasonably good agreement with the available experimental results.

주요 시설물 인접지역의 깊은 터파기굴착에서 변위 및 응력의 계측과 응용

원연호,강추원,양해승 조선대학교 동력자원연구소 1996 動力資源硏究所誌 Vol.18 No.2

The excavation works for deep foundation in urban areas have recently increased complaints of blasting vibration and settlement of ground level. Foundation must be excavated approximately up to 24∼28m depths from the surface. The roads and subway line pass through the excavation area. The Dae-chung station is also located at the nearest distance 5∼35m fron the working site. To protect subway station and adjacient some structures from blasting and settlement, the level of ground vibration, displacements and stress were monitored and analyzed. The results can be summarized as follows : 1. An empirical particle velocity equation was obtained by test blasts at Nassan Missi 860 Officetel construction site. V=K(D/√W)^-n, where the values for n and k are estimated to be 0.371 and 1.551 respectively. From this ground vibration equation, the max, charge weight per delay time against distance from blasting point is calculated. Detailed blasting method is also presented. 2. To measure the horizontal displacement in directions in directions perpendicular to the borehole axis, 6 inclinometers installed around working sites. The displacement at the beginning was comparatively high because the installation of struts was delayed, but after its installation the values showed a stable trend. Among them, the displacement by 3 inclinometers installed on a temporary parking area showed comparatively high values, for example, the displacement measrued at hole No. IC-1 recorded the max, 57.33mm for 7 months. So, all of these data was estimated below a safe standard value 103mm. 3. Seven strain gauge meter was installed to measure value of maximum stress was-465㎏f/㎠, -338.4㎏f/㎠, 302.3㎏f/㎠ respectively. In compare to the allowable stress level of steel, they are estimated to be safe.

도시거주자의 혈중 카드뮴 농도와 간 및 신장 기능과의 상관성 평가

김호현,임영욱,임종한,양지연,신동천 한국환경독성학회 2003 환경독성보건학회지 Vol.18 No.1

The possibility that liver and kidney function is adversely affected by current levels of environmental exposure to cadmium (Cd) as investigated in adult men and women in the general population in Seoul. From February to August in 2001, blood and morning spot urine samples were collected from 136 not occupationally exposed group (age range 20~75 years) at 4 survey sites throughout Seoul. Liver and kidney function parameters in serum and urine were examined by conventional methods. The questionnaire included factors, i.e. sex, age, smoking, alcohol, diet habit etc. The geometric mean values for Cd in blood (Cd-B) were 1.43 μg/l. It seemed prudent to conclude that liver and kidney function as not disturbed by the current environmental exposure to Cd in study.

편심 압축력을 받는 스테인리스 각형강관 기둥의 곡률형상에 따른 좌굴내력에 관한 실험적 연구

장호주,서성연,양영성 대한건축학회 2005 大韓建築學會論文集 : 構造系 Vol.21 No.2

This study is a series of experimental investigation on the buckling strengths of eccentrically compressed cold-formed stainless steel square hollow section columns. The principal parameters in this study are slenderness ratios(λ=30, 50, 70) and magnitude of eccentricity e(0, 2.5, 5.0, 7.5. 10cm) on the direction of end-moment. The direction of end-moment means 3 different bending moment distributions. Objectives of this paper are to obtain the maximum loads and moments by performing an experimental work and to compare the experimental behaviors with the design standard curves, AIK-LSD and AISC-LRFD, AIJ-LSD, SIJ-ASD curves. The ultimate buckling strengths and bending moments of square section members were evaluated by a method in accordance with design standard curves. Therefore this paper attempts design standard for the use of these stainless steel columns as structural compression members. The numerically obtained ultimate buckling strengths and bending moments design standard curves of beam-columns showed a reasonably good agreement with the available experimental results.