초등학교 및 학원 실내 공간 내 알데히드류 노출로 인한 건강위해성 평가

김호현,양지연,이청수,박주희,신동천,임영욱 한국실내환경학회 2012 한국실내환경학회지 Vol.9 No.1

The purpose of this study was to investigate the health risk and management of childhood exposure to indoor aldehydes in elementary-schools and academies. The samples were collected at children’s facilities (50 elementary-schools and 46 academies) in summer (Aug ~ Sept, 2008), winter (Dec 2008 ~ Feb, 2009) and Spring (Mar ~ Apr, 2009) periods. The overall mean concentration of formaldehyde was 68.3 ㎍/㎥ and 27.2% of exceeded the 100 ㎍/㎥ by the school health guideline. The concentration ratio of Indoor air and outdoor air (I/O) of aldehydes exceeds 1.0. The level of indoor air contamination did appear to be high, and 24.6% of the academies evaluated had exceeded the formaldehyde level specified by the public health act (120 ㎍/㎥). We estimated the lifetime excess cancer risks (ECRs) of formaldehyde, and the hazard quotients (HQs) of non-carcinogens (acetaldehyde and benzaldehyde). In addition, for carcinogens, the excess cancer risk (ECR) was calculated by considering the process of deciding cancer potency factor (CPF) and age dependent adjust Factor (ADAF) of the data of adults. The average ECRs of formaldehyde for young children were 1×10-6~1×10-5 level in all facilities. HQs of formaldehyde did exceed 0.1 for all subjects in elementary school.

어린이 실내 활동공간 내 3P(Phthalate, PBDE, Pesticide) 노출과 위해 관리

김호현,Kim, Ho-Hyun 한국교육시설학회 2014 교육시설 Vol.21 No.6

Case Studies for the Ratification of Stockholm Convention on Persistent Organic Pollutants with Specific Exemption in South Korea

김호현,신동천,양지연,이준상,이재영,임영욱 환경독성보건학회 2009 한국독성학회 심포지움 및 학술발표회 Vol.- No.-

폐쇄성 대장암 수술에 있어서 스텐트 삽입술의 유효성

김호현,김호군,조상혁,허정욱,류성엽,김형록,김동의,김영진,주재균 대한대장항문학회 2009 Annals of Coloproctolgy Vol.25 No.2

Purpose: Treatment for malignant colonic obstruction consists of a multiple-staged emergency operation. In recent years, some authors have reported low morbidity and mortality rates using self-expandable metallic stents. This study is designed to evaluate the usefulness of self-expandable metallic stents in patients with malignant colonic obstruction. Methods: The records of 38 patients who had undergone surgery for malignant colonic obstruction at our institution between January 2004 and August 2006 were reviewed retrospectively. Seventeen patients were treated with elective surgery after stent insertion, bowel decompression, and bowel preparation (stent group), and 21 patients were treated with emergency surgery without stent insertion (control group). Results: There were no significant differences in age, sex, tumor node metastasis (TNM) stage, or cancer position between the two groups (elective operation after stent insertion vs. emergency operation). Of the 17 patients who underwent elective operation after stent insertion, primary anastomosis was possible in 15 (88.2 vs. 57.1% in the control group), with a lower need for a colostomy (11.8 vs. 42.9% in the control group, P=0.036). Also, the number of patients with severe complications (17.6 vs. 47.6% in the control group, P=0.048) and the hospital stay (10.82 vs. 13.43 days in the control group, P=0.032) were significantly lower in the study group. Conclusion: Placement of a self-expandable metallic stent for malignant colonic obstruction is a safe and effective procedure. It can reduce the colostomy, mortality, and morbidity rates and the hospital fee for treatment. Purpose: Treatment for malignant colonic obstruction consists of a multiple-staged emergency operation. In recent years, some authors have reported low morbidity and mortality rates using self-expandable metallic stents. This study is designed to evaluate the usefulness of self-expandable metallic stents in patients with malignant colonic obstruction. Methods: The records of 38 patients who had undergone surgery for malignant colonic obstruction at our institution between January 2004 and August 2006 were reviewed retrospectively. Seventeen patients were treated with elective surgery after stent insertion, bowel decompression, and bowel preparation (stent group), and 21 patients were treated with emergency surgery without stent insertion (control group). Results: There were no significant differences in age, sex, tumor node metastasis (TNM) stage, or cancer position between the two groups (elective operation after stent insertion vs. emergency operation). Of the 17 patients who underwent elective operation after stent insertion, primary anastomosis was possible in 15 (88.2 vs. 57.1% in the control group), with a lower need for a colostomy (11.8 vs. 42.9% in the control group, P=0.036). Also, the number of patients with severe complications (17.6 vs. 47.6% in the control group, P=0.048) and the hospital stay (10.82 vs. 13.43 days in the control group, P=0.032) were significantly lower in the study group. Conclusion: Placement of a self-expandable metallic stent for malignant colonic obstruction is a safe and effective procedure. It can reduce the colostomy, mortality, and morbidity rates and the hospital fee for treatment.

혈부축어탕이 Triton WR-1339에 의한 고지혈증 유발 생쥐 간조직내 지질 축적 억제에 미치는 영향

김호현,방혜정,강윤호,박인식,안상현,김진택,이해풍,Kim, Ho-Hyun,Bang, Hyui-Jeng,Gang, Yun-Ho,Park, In-Sick,Ahn, Sang-Hyun,Kim, Jin-Tack,Lee, Hai-Poong 대한동의생리학회 1999 동의생리학회지 Vol.14 No.2

After Triton WR-1339 (TX; 600mg/kg) intraperitoneal injection, hepatic tissues of ICR mice were intragastric injected with Hyulboochucketang extract(HCE; 3.3ml/kg/day) were observed to investigate the suppressive effect of lipid accumulation that evoke by the antihyperlipidemic effect of HCE. These hepatic tissues were fixed in fromol-calcium solution and were cryocut. These tissues stained by H&E for general morphology, sudan black B for lipid and perchloric acid-naphthoquinone(PAN) method for cholesterol. After TX treatment, the increase of hepatocyte having meshlike cytoplasm(HHMC) were shown in all hepatic lobules and the hepatic plates were disappeared in the aggregative region of HHMC. The number of blue black colored lipid drop and dark green colored asterisk shaped cholesterol particle in hepatic cytoplasm were increased and the size of lipid drop and cholesterol particle were enlarged. But, in HCE-treated mice, the HHCM were disappeared and hapatic plate were rearranged. The number of lipid drop and cholesterol particle were decreased than TX-treated mice and the size of lipid drop and cholesterol particle were diminished. As results indicated that the HCE work on the suppression of lipid accumulation in hepatic tissue of hyperlipidemic mice caused by disturbance of lipid metabolism.

Cyclosporin A의 肝毒性에 미치는 右歸飮의 影響

金昊顯,申興默,金吉萱 동국대학교 한의학연구소 1993 東國韓醫學硏究所論文集 Vol.2 No.2

The purpose of this study is to observe the effect of Woogyuyem on serum reaction and hepatic tissue in Cyclosporin A treated rats. In this study, the experimental rats divided two group(Contro1 group and Sample group). Under the Same condition, both control group and sample group were injected to abdomen with Cyclosporin A for 7days. And then, control group were administered water, sample group were administered Woogy-uyeum for 30days. The change of transaminase and bile acid and SOD activity in blood serum, hepatic tissue were measured at 3rd, 7th, 15th, 30th day. The obtained results are surnmarised as follows : 1. In the change of SGOT contents, as compared with control group, sample group was significantly decreased at 7th and 15th day. 2. In the change of SGPT contents, as compared with control group, sample group was signi�icantly decreased at 15th day. 3. In the change of serum bile acid contents, as compared with control group, sample group was significantly decreased at 7th and 15th day. 4. In the change of serum SOD activity, as compared with control group, sample group was significantly increased at 15th and 30th day. 5. In the change of hepatic tissue, as compared with control group, the vacuolation of hepatocytes in the sample group was reduced, the liver plates were reconstructed, and the epitherial cell wasn't destructed.

Risk Assessment of Volatile Organic Compounds (VOCs) and Formaldehyde in Korean Public Facilities: Derivation of Health Protection Criteria Levels

김호현,Young-Wook Lim,신동천,Jong Ryeul Sohn,양지연 한국대기환경학회 2011 Asian Journal of Atmospheric Environment (AJAE) Vol.5 No.2

This study suggests criteria to conduct a risk assessment of VOCs and formaldehyde in uncontrolled public facilities. Pollutants and facilities were selected based on two years of monitoring data and exposure scenarios in 573 uncontrolled public facilities, composed of 10 types of public institutions. With the exception of social welfare facilities, lifetime ECRs of formaldehyde and benzene in each facility were higher in employees than in users, except in social welfare facilities. In social welfare facilities, the risk of benzene for users (1×10^-5) was higher than that of workers (1×10^-6) because facility users live in the facility 24 hours per day, compared to workers who spend an average of 8 hours per day in the facility. The risk of benzene to workers in restaurants, academies,performance halls, internet café and pubs were estimated as high as 1×10^-4 and the risk to workers in the theaters and karaoke bars were recorded as 1×10^-5. Because lifetime ECRs of carcinogens exceeded 1×10^-4 for workers and users in most facilities, risk management of formaldehyde and benzene in these facilities is necessary. Although HQs of toluene and xylenes did not exceed 1.0, their HQs did exceed 0.1 in some facilities, so they were evaluated as potentially harmful materials. Additionally,criteria for health protection in IAQ by facility are suggested at 60-100 μg/m^3 for formaldehyde,400-500 μg/m^3 for TVOCs, 10-20 μg/m^3 for benzene,150-170 μg/m^3 for toluene and 100 μg/m^3 for xylenes,based on the survey on IAQ and HRA methodology. The excess rates of IAQ to health protection criteria in all facilities were 16% for formaldehyde, 8% for TVOCs and benzene, 9% for toulene, and 5% for xylenes.

함정용 음향 소해 윈치 축 베어링 군직생산 기술에 관한 연구

김호현,정경민,윤성일 국방기술품질원 2023 국방품질연구논집 Vol.5 No.2

To urgently treat foreign-damaged plain bearings, a technical investigation is conducted through material analyses and hardness measurements. The British standard of bearing materials, BS-1200, G1, is based on the operating conditions and lubrication. This study investigates the wear engineering of a plain bearing with a marine winch shaft. An analysis of the investigated technology was intended to secure the function and quality of alternative KS standard materials that are equivalent to foreign products. Based on a comprehensive analysis of damaged foreign plain bearings, navy shipyard direct manufacturing was completed using equivalent-class KS bearing materials.

4차 산업혁명 시대의 인재상에 따른 유아교육의 방향 모색

김호현,김충일 한국열린교육학회 2017 한국열린교육학회 소식 Vol.2017 No.추계

4차 산업혁명 시대는 이전의 산업혁명과는 다른 차원의 일들이 벌어질 것으로 예측이 되고, 새로운 능력이 요구되는 불확실성과 불안전성의 시대라 일컬어진다. 이러한 4차 산업혁명 시대에 대비하기 위하여 유아교육은 어떤 역할을 할 수 있을까. 이에 대답하기 위하여 이 연구는 유아교육의 발전 역사로부터 유아교육이 현재 지향하고 있는 몇 가지 방향을 알아본다. 그리고 4차 산업혁명 시대에 요구되는 능력을 교육목표의 인지, 정의, 심동적 영역으로 구분하여 살펴본 뒤 현재의 유아교육에서 이 영역들을 어떻게 다룰 수 있을지 알아보았다. 그 결과 프뢰벨로부터 시작된 아동중심 사상은 홀, 피아제, 듀이를 거치며 심리학, 사회학, 포스트모더니즘 등의 학문을 만나면서 발달적으로 적합한 실제, 프로젝트 접근, 사회적 효율성, 권리와 민주주의 교육의 네 가지 줄기로 나누어졌음을 이해했다. 4차 산업혁명 시대에 요구되는 능력을 인지적 영역(상황 맥락적 지능), 정의적 영역(정서지능, 영감지능), 심동적 영역(신체지능)으로 구분되었다. 이 영역들이 현재 유아교육이 지향하는 네 가지 방향 안에서 어떻게 교육이 될 수 있을지 알아보았다.

성서신학의 민중이해

김호현 대신대학 1991 논문집 Vol.11 No.-

1960년초에 남미에서 해방신학이 발생하여 우리나라에 영향을 주었다. 그 영향으로 70년대에 와서 우리나라는 '민중의식'이 야기되어 정치적, 경제적으로 소외된 계층이 이른바 민중집단을 형성하여 반정부 시위운동을 전개하였다. 정부는 유신체제로 전환하여 강력한 독재정권을 유지하기에 이르렀다. 이시기에 한국의 신학들은 신실한 민주정부체제를 갈망하였으며, 국민의 기본인권인 자유를 누리도록 천명하게 되었다. 이 철학과 사상을 체계화 하기 위하여 성서에 입각한 '민중신학'을 수립하게 된 것이다. 민중신학의 목표는 정치적, 경제적으로 소외된 계층에게 더 관심을 가지고 그들에게 복음을 전하며, 사람답지 못한 삶의 상태에서 하나님의 형상인 사람다운 상태로 회복시키고저 하는 것이다. 따라서 본 논문의 목적은 한국교회로 하여금 고난당하고 소외된 민중에게 더욱 관심을 갖고 그들에게 참 삶의 모습을 돼 찾게하여 평안과 소망을 주고자 하는 것이다. 본 논문의 구성은 남미에서 형성된 해방신학의 모체와 한국민중신학자들의 논문가 학자를 비교 분석하여 성서적 입장에서 민중을 규정해 보았고, 신·구약성서에서 하나님과 예수는 민중에게 어떤 은총을 주었는가를 도출해 내고저 노력하였다.