김천대학 사회교육 활성화 방안에 관한 연구

고정환 ; 윤옥현 ; 박홍기 ; 전기환 ; 김상민 ; 김학민 ; 박희룡 김천대학교 1999 김천대학교 논문집 Vol.20 No.-

The social education that is provided for the people will be an important part of the national growth in the 21 century. This study was taken to present the desirable direction that Kimcheon College Continuing Education has to make progress as a central organization with perceiving the importance of continuing education for the Kimcheon citizen. To achieve the objective of the study, examined a sample of 592 citizen and students from Kimcheon City and Kimcheon College. The survey revealed the following results : 1. Offer the effective operation of education policies and curriculums. 2. Perform the role of foreign language education center. 3. Introduce the saving credit system. 4. Operate the special lectures for the students of the high school graduating class after the national scholastic achievement test for university and college entrance. 5. Suppert the special skills education for high school students after-school hours. 6. Administer the new employment program. These results showed the desirable direction that the Kimcheon College Continuing Education has to take some actions for the Kimcheon citizen.

19세기 女唱歌曲과 시조의 상품화

고정희 釜山大學校 韓國民族文化硏究所 2004 한국민족문화 Vol.24 No.-

The goal of this paper is to reexamine the sensibilities of 19th century sijo, which have been called "retrogressive romanticism" or "emotional overexposure." In order to do this, an analysis was undertaken, utilizing the concept of "merchandization," of the sensibilities of songs sung by women. The results were as follows. Firstly, in songs sung by women, nature was merchandized as material objects related to emotion that were interchangeable with emotion. Secondly, songs sung by women exchanged such emotions as "love" and "parting"--emotions difficult to merchandize--with "words," making these aesthetic merchandise. Thirdly, merchandized "love" and "parting" tended toward a strong "sentimentality." By labeling sentimentality a feminine sensibility, it was marginalized as an "other," allowing men to enjoy the feeling that they were superior. The protests of the marginalized women were hidden within this sentimentality. Songs sung by women primarily reflected the demands of the privileged men, who marginalized nature, emotion, and femininity. Because they contained, at the same time, traces of that which had been marginalized, songs sung by women exhibited many complex aspects. The way to richly revive the sensibilities of 19th century sijo depends on how well we interpret the quality of being "merchandise" that is engraved in this complexity.

폐결핵 환자 혈청에서 수용성 Interleukin 2 수용체 및 Adenosine Deaminase 활성도에 관한 연구

고정희,박성규,백상현,박찬권,박병수,안진영,최우석,박정규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

Interleukin-2 (IL-2) induces T cell proliferation in an autocrine manner and provides a means by which antigen triggered T cells can be clonally expanded in vitro. During the following activation, the activity of IL-2 is mediated by specific high affinity IL-2 binding membrane receptors which are expressed shortly after activation. In this process, a 42 KD-fragment (soluble IL-2R) is continuously cleaved off and circulates as a soluble marker of T lymphocyte activation. Elevated level of soluble IL-2R has been identified in the serum of patients with malignant autoimmune and allergic disorders, systemic parasitic infection, undergoing graft versus host disease, acute or chronic lymphocytic leukemia and HIV-infection. ADA (adenosine deaminase) completes the process of differentiation of T cell and is essential for progression of T cell maturation. Therefore level of ADA is to correlated with magnitude of T cell immune response. The fact that expression of sIL-2R and ADA activity increases in peripheral blood T-lymphocytes of patients with active pulmonary tuberculosis suggests that T cell activation might have a major role in the pathogenesis of pulmonary tuberculosis. In order to evaluate the T cell immune response in pulmonary tuberculosis, we measured the serum concentration of sIL-2R and ADA activity in 17 patients with current pulmonary tuberculosis, 10 chronic inactive pulmonary tuberculosis, 10 as normal controls. (1) Current pulmonary tuberculosis had significantly higher levels of sIL-2R (237.24±95.47)when compared with those of inactive tuberculosis (78.6±11.06). and the control (68.17±15.4) group. (2) ADA activity in current pulmonary tuberculosis was significantly increased (34.41±20.63) when compared with those of inactive tuberculosis (24.7±14.36) and control (17.65± 5.94) group. (3) There was good correlation between sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group. (4) sIL-2R concentration and ADA activity was decreased significantly 6 months after anti-tuberculosis drug medication. In conclusion, sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group was increased when compared with those of inactive pulmonary tuberculosis and the control group. By the way, T cell mediated immune response was enhanced in current pulmonary tuberculosis, but in inactive chronic pulmonary tuberculosis who had treated by antituberculosis drug medication, the concentration of sIL-2R and ADA activity was nearly normal.

17세기 田家時調의 서정적 리얼리티에 관한 연구 : <栗里遺曲>을 중심으로

고정희 고려대학교 민족문화연구원 한국문학연구소 2002 한국문학연구 Vol.- No.3

The goal of this paper is to examine the categorical validity of "rural sijo"(jeonga sijo), a new category that has received attention and is distinguished from "nature sijo"(gangho sijo), through an explanation of the lyrical reality of "Yulliyugok."Even if the "realistic realization of the countryside" is persented as reality in nature sijo, the hypotheses used to inyerprect this are the interpretional attitude of an illusiodary would that realizes the concept of poverty.We can call this an illusionary reality.The reason rural sijo have received attention is that they interpret the phrase "realistic realization of the countyside" to mean "as is" and "realistic."This attude, which is in vonflict with illusionary reality, may be called imitative reality.However,rural sijo are influenced by the conventions of nature sijo, and as such it is difficult for its lyrical reality to become a completely imitative reality. In "Yulliyugok," as natural things are processed into artificial things, we can catch a glimpse of a physical definition of nature and an attitude which emphasizes the imition of reality.For example, alcohol is combined with mortal humans desire to escape reality, and the illusionary reality for which alcohol was a medium naturally changes to an imitative reality.Furthermore, it shows the extreme of the physical definition which completely removes the aura of processed foods such as "stremed chicken" and "steamed crab."The "red bean porridge" and "salted kimchi" in "Yulliyugok" may be replaced by any daily foods in a farming household, but they become allegories for the personal and conceptual ideal of "simplicity" and "indifference."In this way, even while the lyrical reality of rural sijo objectifies nature, the original meaming of nature is awakened as allegory. Particularly noteworthy in "Yulliyugok"is the fact that, while imitating the process of making "read bean porridge"-a processed food that is a union of nature and human skill-the typical meaning of conventional language is combined with the realistic meaning of individual poetic language. As a result, nature and human skill, nature and the cultural world are united and a new reality is created that is neither an illusionary reality or an imitative reality. This reality can be called an "allegorical reality." "Allegorical reality," which may be defined as an attitude which tends toward the union of illusion and imitation,is the most basic standard by which the categories of nature sijo and rural sijo are distinguished.

편마비 환자의 보행시 신발 교정에따른 에너지 소모의 감소

서정환,고명환,김연희 大韓再活醫學會 1999 Annals of Rehabilitation Medicine Vol.23 No.1

척수 손상 환자에서의 Euthyroid Sick Syndrome -증례 보고-

서정환,고명환,김근수,김연희 大韓再活醫學會 1998 Annals of Rehabilitation Medicine Vol.22 No.2

2-Acetylaminofluorene으로 유발된 실험적 간암의 TGF-a 및 EGF발혈에 관한 연구

박정희,고영혜,이중달 한양대학교 의과대학 1995 한양의대 학술지 Vol.15 No.2

Transforming growth factor-α(TgF-α) and epidermal growth factor (EGF) are growth factors acting on proliferation and differentiation of cells and expressed in various types of cancer. TGF-αmay be a physiological regulaor during liver development and liver regeneration in injured liver and known as increased in hepatocellular carcinoma. To investigate the role of TGF-αand EGF in hapatocarcinogenesis, author had undertaken an experimental study of hepatic carcinogenesis induced in 50 rats by feeding 2-acetylaminofluorene(2-AAF) in diet. The animals were sacrificed periodically after 2-AAF administration, and each liver was examined grossly and microscopically and immunostained with monoclonal antibody for TGF-αpolyclonal antibody for EGF. 1. At the third week of the experiment, the oval cells were markedly proli ferated and extended from the periphery to central areas of hepatic lobules. The altered hepatic foci, including acidophilic cell area on the fourth week and clear cell area on the second month were noted. At the third month, hype rplastic nodules developed. At the seventh month, one case of hepatocellular carcinoma and angiosarcoma were noted. At the eighth month, four cases of hepatocellular carcinoma of trabecular type were noted. Among these, three cases of squamous cell carcinoma on the neck skin occurred. 2. The control livers expressed only a few scattered hepatocytes positive for TGF-αin hepatic lobule. At the third week after 2-AAF administration, the hepatocytes exihibiting positive reaction were more widely distributed along the portal areas and around central veins. At the third month, several of the hyperplastic nodules showed strong to moderate positive reaction for TGF-α. The relationship between the TGF-αexpression and cytomorphologic changes in nodular hepatocytes was not present. All of the hepatocellular carcinoma cells and cells in the neighboring nodules at the seventh and eighth months expressed TGF-α. Oval cells were negative for TGF-αand bile ductular cells showed only focal positivity. 3. EGF was negative in cells of the centrol livers and most experimental livers. At the eighth month, one case of hepatocellular carcinoma and tree cases of squamous cell carconoma showed positive reaction for EGF. Above results suggest that TGF-α, may play a role in hepatocarcinogenesis by the mechanism that TGF-αacts as promotor for the transformation of initiated hepatocytes by 2-AAF in multistep of hepatocarcinogenesis.

호흡율 측정기를 이용한 폐수의 외부탄소원 이용가능성 평가

최은희,고주형,임정훈,부경민,김창원 부산대학교 환경문제연구소 2000 環境硏究報 Vol.18 No.-

In this research, we measured Readily Biodegradable COD(Ss) using respiration meter which measured OUR and calculated respiration rate due to calculate organic matter portion of external carbon sources because known organic matter analysis methods i.e. COD, BOD did not measure amount of organic matter which was used in denitrification. Based on the experimental results, leather wastewater had 40.3% Ss in TCOD and food fermentation liquid, alcoholic wastewater and petrochemical wastewater was 38%, 38% and 28.3% respectively. However in case of considering of flowrate and concentration, flood fermentation and alcoholic wastewater was revealed that they were effective external carbon sources

대유행인플루엔자 대비를 위한 의료기관-바탕 탁상훈련 : 고안 및 평가

설희윤,김지량,권보란,목정하,이선희,곽임수,정진우,김정수,고옥배,조은희,김성순,신상숙,이상원 대한감염학회 2008 감염과 화학요법 Vol.40 No.2

목적 : 의료기관의 범유행 인플루엔자에 대한 효과적인 대비를 위한 훈련방법으로서 의료기관-바탕 탁상훈련 (hospital based tabletop exercise)의 유용성과 순응도를 평가하기 위해서 시행되었다. 재료 및 방법 : 탁상 훈련은 부산대학교 병원에서 시행되었으며 병원의 주요의사결정권자 및 주요부서 대표자, 실무자 42명이 지휘부, 진료부, 지원부 3그룹으로 나뉘어 훈련에 참가하였다 탁상훈련의 시나리오는 의료기관의 자체 훈련을 위해서 고안하였으며 현재 동남아에서 유행하고 있는 H5N1 인플루엔자가 국내에 처음으로 유입되어 확산되는 과정에서 의료기관에서 발생할 수 있는 상황을 3가지 모듈로 구성하였다. 훈련 평가는 훈련 전후에 각각 익명의 설문조사를 시행하였다. 결과 : 훈련에 초청된 참여자 42명 중 37명(88%)이 실제 당일 훈련에 참여하였다. 훈련에 참여한 37명의 직원 중에서 훈련 전 시행한 설문에 27명(73%)이 응답하였다. 훈련 전 정가에서는 훈련을 통해 획득하고 싶은 지식이나 기술의 우선 순위를 물었으며, 참여자들이 가장 중요하다고 생각하는 항목은 대유행인플루엔자 바이러스에 대한 지식 향상 22%, 병원 각 부서가 취해야 할 계획 및 의사소통과 관련된 지식 향상 19%, 지역사회 병원들 간의 상호협력을 향상시킬 전략 계발이 19%이었다. 그룹토의 동안에는 환자의 조기 발견 이후 대응에 대한 토론이 많았지만, 구체적인 부분이 미흡하였고, 대유행 인플루엔자에 대한 기본적인 이해가 부족하였다. 훈련에 참여한 37명의 직원 중에서 훈련 후 시행한 설문에 21명(57%)이 응답하였다. 훈련 후 평가에서 탁상훈련의 전반적인 만족도에 대한 질문에서 81%가 만족하였다고 답변을 하였고, 새로운 것을 배우는데 유용했는가 대한 질문에도 86%가 유용했다고 답변하였다. 결론 : 탁상훈련은 의료기관의 대유행인플루엔자 대비에 효과적인 훈련방법이라고 생각되며 훈련을 통해 의료기관 내의 여러 부서들이 각 의료기관의 특성에 맞는 현실적이고 실제적인 대비 계획을 수립하는데 도움을 줄 것으로 기대된다. 그러나 향후 토른 촉진, 구체적인 결과에 도달을 유도할 수 있는 질문, 끼워넣기 개발, 적절한 시간 등에 대한 연구가 필요할 것으로 생각된다. Background : To evaluate the usefulness and compliance of a hospital-based tabletop exercise in setting of pandemic influenza in hospitals. Materials and Methods : Tabletop exercise was held in Pusan National University Hospital and forty two hospital employees were invited to participate in the exercise. The scenario for hospital-based tabletop exercise was designed. It consisted of three modules, which simulated the influx and outbreak of H5N1 influenza that was epidemic in Southeast Asia. Pre-, post-exercise surveys were completed by anonymous questions. Results : Thirty-seven (88%) of 42 invited participants attended exercise. AII members of the administration group and the ancillary services group participated. But, only 77% members of the clinical services group participated. In pre-exercise survey, priorities of eight goals regarding skills and knowledge during exercise were inquired., The highest priorities pointed out by the respondents were "Increase the knowledge of pandemic influenza" (22%), "Development of strategies for optimal communication among employees within specific department" (19%) and "Development of strategies for improved coordination between facilities within the health system" (19%). Twenty-one (57%) of participants completed the post-exercise surveys. At post-exercise surveys, 81% of the participants stated that the tabletop exercise was extremely or very useful, 86% of the participants also stated that it increased their knowledge of pandemic influenza. Conclusion : Tabletop exercise is an effective modality for increasing pandemic influenza preparedness in hospitals, and this method is useful for guiding preparedness activities within the hospital environment. Further studies to determine the appropriate method of discussion, questionnaire, duration of exercise and injection are needed.

임균과 대장균의 Ampicillin 내성발현 유전자에 관한 연구

박정희,고영수 漢陽大學校 韓國生活科學硏究所 1993 韓國 生活 科學 硏究 Vol.- No.11

The plasmids carrying ampicillin resistance, pNG3A and pECl15B originating from Neosseria gonorrhoeae and Escherichia coli, respectively, were isolated and characterized. Restriction tests with various endonucleases for recognition sites localized in the pNG3A showed a single site for each of Pst I, Hind III, Ava I, Pvu I and Bgl I, and two sites for BamH I. Restriction tests of pECl15B showed a single site for each of Xba I and Tthlll I, two sites for each of BamH I, Cla I, Pvu I. EcoR V. Sph I and Ava I, and three sites for each of Pst I and Bgl I. Performing multiple digestion followed by sizing their fragments, restriction endonuclease maps of the pNG3A and pECl15B were constructed. The restriction pattern of BamH I fragments of pNG3A(2.4Kb) and pECl15B(1.5Kb) showed significant structural homologies to that of Tn3, a transposon of TnA. When the BamH I fragments were cloned into ampicillin sensitive modified-pBR322 vector, each of recombinant plasmids, pBRBHI and pBRl15B, from pNG3A and pECl15B, respectively, fully expressed ampicillin resistance. Through the series of experiments, it can be realized that ampicillin resistance of these strains tested was expressed by R-plasmid carrying bla gene which was acquired by the insertion of Tn3.