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      • 구리이온을 도입한 Acrylonitrile-Acrylic Acid계 공중합체의 도전성에 관한 연구

        손원근,맹기석,김동철,송해영 忠南大學校 産業技術硏究所 1987 산업기술연구논문집 Vol.2 No.2

        The AN-AA copolymer-Cu(Ⅱ) and Amidated AN-AA copolymer-Cu(Ⅱ) complex were the most stable in the pH range of 9. The morphology of Cu(Ⅱ) complex and CuxS-induced had changed into compact form. The thermal stability for Cu(Ⅱ) complex and CuxS-induced had been determined through DTA and TGA measurement. As result, it has been observed that thermal stability for Cu(Ⅱ) complex were stabilized less than that of copolymer. The Cu(Ⅱ) complex exhibited surface resistivity around 10Ω㎝ when modified iodine in acetone. The resistivity was significantly affected by the amounts of added cupric chloride, iodine and results were statisfactorily obtained by adding more than 20wt% of Cupric chloride and about 1.0wt% iodine. The optimum condition for the introducing of CuxS was at the CuSO₄concentration of 30g/ℓ and the reaction time of 3hrs. The CuxS-induced electrical conductivity of copolymer was higher by order of 10 than that of the Cu(Ⅱ) complex.

      • 두 마리의 면역매개성 혈고판감소증 개에서의 MMF를 이용한 치료

        손혜진,박형진,서경원,송근호 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

        Two dogs (case 1: 4-years-old female Dachshund, case 2: 1-years-old male maltese) were reffered with petechia. Result of blood analysis and coagulation test reveled immune-mediated thrombocytopenia in all dogs. Treatment with MMF for them, case 1 present steroid-induced hepatopathy, case 2 present anemia, so treated with Human IgG and blood transfusion. 3(case 1) or 2(case 2) months after initial treatment, clinical features were improved, and continuous monitoring is needed.

      • KCI등재
      • ESI-K의 타당화를 위한 기초연구

        손원경,최혜진 부산대학교 영유아보육연구소 2002 영유아보육연구 Vol.8 No.-

        The purpose of this study was to examine validation of the Early Screening Inventory-Kindergarten(ESI-K). The subjects of this study were 139children ranged from 4(1/2)years old to 6 years old and selected from 4 kindergartens and 3 day care centers in Pusan. Tests used for this study were the ESI-K and DDST. The ESI-K is developmental screening instrument which is consisted of 24 items covering three sub-areas such as visual-motor/adaptive, language & cognition, and gross motor. The score can be classified as "OK", "Rescreen" and "Refer". Children who get "OK" is presumed to be developing normally. Children who get "Rescreen" should have ESI-K readministered in 6 to 8 weeks. Children who get "Refer" should be refered immediately for more thorough assessment. The results of this study are as follows: First, the range of the ESI-K item difficulty was from 33.8 to 97.1% and older children tended to perform better on the items than younger children. The ESI-K items discriminated between upper group and the lower group. Second, the Cronbach a was .71. Inter-scorer reliability was .97. The correlations between total score and subarea were .74, .82, .73(p<.01). It is concluded that the ESI-K, with minor modifications, can be used as a valid and reliable developmental screening instrument.

      • KCI등재후보

        치주질환 병인균간의 성장억제 활성도에 관한 연구

        정해원,이상철,정종평,손성희 대한구강생물학회 1988 International Journal of Oral Biology Vol.12 No.1

        In a complex ecosystem such as periodontal pocket, bacterial antagonism may be a determinant in oral colonization and compositional changes of periodontopathic microflora. This study was performed to examine the growth inhibitory activities among the periodontopathic and indigenous bacteria. The growth inhibitory activity was examined as both producers and indicators by stab culture method. Inhibitory activities of cell sonicate and culture supernatant of S. mutans OMZ 65, which showed broad and strong inhibition against periodontopathic bacteria, was examined by the diffusion method. The results were as follows. 1. B. gingivalis, B. intermedius and A. actinomycetemcomitans strains showed weak inhibition against homologous and heterologous strains. Two among three strains of B. intermedius showed moderate inhibition against one strain of B. gingivalis and all of A. actinomycetemcomitans strains showed inhibitory activity to B. gingivalis. 2. The strains of S. mutans showed broad and strong inhibition against B. gingivalis, A. actinomycetemcomitans strains and moderate inhibition against B. intermedius, but S. sanguis strains showed weaker growth inhibitory spectra than those of S. mutans strains. However, the pattern of inhibitory activity showed, to a certain extent, species-specific. 3. S. mutans strains showed broader inhibitory spectrum against A. a. Korean strains than that of S. sanguis strains. But A. actinomycetemcomitans Korean strains has rarely showed growth inhibition against S. sanguis. 4. A. actinomycetemcomitans Korean strains showed weak inhibitory activity to B. gingivalis and no inhibitory activity to B. intermedius. 5. S. mutans showed strong inhibitory activity to homologous strains and typically species-specific than these of S. sanguis. Further investigation should be needed to clarify a relationship between the presence of plasmids and bacteriocin activity.

      • 이온교환체로서 Polyphenylene Sulfide Sulfonic Acid에 관한 연구

        전병광,손원근,서구원,맹학영,김동철,송해영 충남대학교 공업교육연구소 1994 論文集 Vol.17 No.1

        Sulfonated poly(phenylene sulfide)(S-PPS) was prepared by the reaction of poly(phenylene sulfide)(PPS) with fuming sulfuric acid. The sulfonation was confirmed by the high intensity band of the SO_3H group at 1190 cm^-1. Thermally crosslinked S-PPS was used for a cation exchange polymer with high thermal stability. The ion exchange capacity of soluble S-PPS(H-form) and insoluble S-PPS(H-form) was 5.16meq/g and 3.50meq/g, respectively. The ion exchange capacity and IR absorbance at 1190cm^-1 of S-PPS were decreased as the curing temperature was increased.

      • Urapidil, Labetalol의 투여가 기관내 삽관시 심혈관계에 미치는 영향

        신용섭,윤석화,손수창,이원형,이정은,황원재,김만수,김영주,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

        We have examined the comparative efficacy of small doses of intravenous urapidil and labetalol in blunting hemodynamic response to endotracheal intubation and surgical incision in 30 patients without cardiovascular diseases. After intravenous urapidil 0.2 mg/kg or labetalol 0.2 mg/kg anesthesia was induced with thiopental 5mg/kg. Endotracheal intubation was facilitated by vecuronium 0.15 mg/kg with priming principle and anesthesia was maintained with enflurane and nitrous oxide in oxygen. Systolic, diastolic and mean arterial pressure and heart rate were measured before administration of the drugs, 5 minute after administration, just prior to endotracheal intubation and 1, 3, 5, 10 minute after intubatin. Also the peak blood pressures and heart rate within 10 minutes after surgical incision were measured. Endotracheal intubation and surgical stimulation were associated with significant increases in blood pressures and heart rate in both urapidil and labetalol group. Comparison of the changes in systolic, diastolic, and mean artrial pressures and heart rate between urapidil and labetalol group showed no significant difference except peak systolic pressure after surgical incision. It is concluded that the pressor response to endotracheal intubation and surgical stimulation are not influenced significantly by urapidil 0.2 mg/kg or labetalol 0.2 mg/kg. However, urapidil and labetalol preloading may be similarly effective in the blunting of the increases in blood pressures with larger doses of the durgs during anesthetic induction.

      • Midazolam의 백서 기관평활근 이완효과와 Flumazenil의 길항작용

        윤석화,신용섭,손수창,이원형,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

        Midazolam have been used widely as adjuvants in both regional and general anesthesia and in high risk patients in the intensive care unit. In the present study we evaluated the effect of midazolam and antagonistic effect of flumazenil on isolated rat tracheal preparations mounted for recording isometric contractile force. Trachea smooth muscle were contracted with acetylcholine (10^-5M, Ach) and potassium chloride (40mM KC1). Midazolam 5x10 exp (-6)M and 5x10 exp (-5)M produced dose-dependent relaxation and flumazenil (3.2 x 10 exp (-7)M), central antagonist of benzodiazepine, pretreatment had no significant change midazolaminduced relaxation. Midazolam probably did not relax airway smooth muscle by activatong central benzodiazepine receptors, as flumazenil did not block the concentration-related relaxation of midazolam. Our study suggests that flumazenil may be used satety for asthmatic patients who have been with midazolam, as flumazenil did not antagonize airway relaxation elicited by midazolam.

      • 충남대학교병원 마취발전의 경향에 관한 분석 : 1967년부터 - 1996년까지 from 1967 to 1996

        최세진,김상수,정규돈,윤석화,신용섭,손수창,이원형,김혜자,이정은 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

        To evaluate the specificity and historical trends of the anesthesia in Chungnam National University Hospital, anesthetic experiences of 83,572 in total performed at Chungnam National University Hospital from January 1967 to December 1996 were analyzed statistically and clinically according to age, sex, surgical department, physical status, elective and emergency surgery, premedicants, IV anesthetics, anesthetic methods, inhalational anesthetics, muscle relaxants. The results were as follows : 1. The number of cases has been steadily increased year by year. 2. The ratio of male to female was 52.8% : 47.2%. 3. According to the age, There were 44,905 cases (54%) in the group of 13-45 years. 4. According to the ASA classification of physical status, most of the cases were belonged to the class 1 & 2 (72.5%). 5. The ratio of elective to emergency was 79.4% to 20.6%. 6. Recently, glycopyrrolate has been used increasingly. 7. Thiopental sodium has been mainly used for intravenous induction agent. 8. General anesthesia has been used mainly. 9. Enflurane is the most common inhalational anesthetic agent. but Isoflurane has been used increasingly. 10. Most of muscle relaxants are Pancuronium & Vecuronium(84.5%).

      • KCI등재

        Study on the Microstructure and Friction Characteristics of ZrN Coatings Containing Cu and Si

        Hae Won Yoon,Han-Chan Lee,Seok Won Son,Kyoung Il Moon 한국물리학회 2020 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.76 No.5

        To improve the mechanical properties of coatings used in cutting tools and automotive parts, ZrCuSiN coatings were deposited in an argon-nitrogen gas mixture using magnetron sputtering at various nitrogen gas flow rates. The structural properties of the fabricated ZrCuSiN coatings were investigated using the friction coefficient, wear coefficient, coating hardness, and elastic modulus via nano indentation and ball-on-disk friction testing. The surface morphology of the coatings was analyzed using scanning electron microscopy (SEM). The structural characterization results show a typical face-centered cubic ZrN structure with peaks in the (111) and (200) directions. The highest hardness was obtained for coatings deposited at a nitrogen gas flow rate of 5 sccm, and the coefficient of friction was lowest at a nitrogen gas flow rate of 3 sccm. It was found that the high hardness of the coating causes wearing of the counterpart. In contrast, a 3 sccm coating with stable hardness and coefficient of friction was found to be the most optimal.

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