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      • 7두의 개에서 배설성 요로조영술을 통한 신장 기능 평가

        최윤정,이기자,최형준,이용진,박성준,송근호,정성목,최호정,이영원 忠南大學校 獸醫科大學 動物醫科學硏究所 2005 動物醫科學硏究誌 Vol.13 No.-

        Excretory urography is a type of contrast study used to verify and localize upper urinary tract disease. It is an inexpensive and easy way to visualize of anatomic and functional status of the kidney and has been used as a primary imaging modality for the evaluation of urinary tract abnormalities. We describe urological signs of 7 dogs who examined with excretory urography and ultrasonography. Six cases were referred to veterinary medical teaching hospital. Chungnam national university (VMTH, CNU) to evaluate renal function after the treatment for renal failure and one case was referred showing hematuria. In case 1, 2 and 4, blood test and urinalysis was normal and the results of excretory urography presented that renal function were normal range. In case 3, the results of urinalysis, ultrasonography, and excretory urography except blood test presented abnormal kidney and hydronephrosis was diagnosed. In case 5 and 6, blood test, urinalysis, ultrasonography and excretory urography indicated renal failure. In case 7, blood test, urinalysis and ultrasonography presented partially abnormal signs, however, the results of excretory urography was normal range.

      • Pomeranian에서 발생한 치주 질환에 의한 비염 1례

        이기자,최윤정,최형준,이용진,최호정,이영원,정성목 忠南大學校 獸醫科大學 動物醫科學硏究所 2005 動物醫科學硏究誌 Vol.13 No.-

        A 10-year-old spayed female dog with history of persistent nasal discharge and halitosis was presented. In oral examination, there were severe dental calculi and gingivitis. The radiographic imaging showed lesions of left nasal cavity and periodontal membrane. In computed tomographic imaging, there are increased density of left nasal cavity, loss of nasal concha and partial defect of nasal septum. Many inflammatory cells were observed in nasal cytology. The result of culture from nasal smear was negative. All these findings result in rhinitis by dental calculi and gingivitis. The dog got improved after scaling, tooth extraction, and medical treatment.

      • SCIESCOPUSKCI등재

        식도의 원주상피 피복 점막에서 점액유전자 발현 및 세포증식능에 대한 연구

        최석채 ( Suck Chei Choi ),김용성 ( Yong Sung Kim ),김기훈 ( Ki Hoon Kim ),김헌수 ( Hun Soo Kim ),조향정 ( Hyang Jeong Jo ),윤기중 ( Ki Jung Yun ) 대한소화기기능성질환·운동학회 2007 Journal of Neurogastroenterology and Motility (JNM Vol.13 No.1

        목적 : 바렛식도는 지속적인 위식도역류 등으로 원위부 식도에 정상적으로 존재하는 편평상피세포 대신에 배상세포를 포함하는 장형 원주세포로 식도 점막이 피복되는 것을 말한다. 그리고 이형성을 거쳐 선암종으로 진행할 수 있기 때문에 이형성 이전 단계인 바렛식도의 발암과정에 대한 연구가 필요하다. 이에 바렛식도와 배상세포를 포함하지 않은 원주세포만 있는 식도를 대조군으로 하여 점액유전자 및 세포증식능에 대해 비교 연구하였다. 대상 및 방법 : 임상 및 내시경적으로 바렛식도가 의심되어 원위부 식도에서 생검한 환자들 중에서 배상세포가 있어 조직학적으로 바렛식도로 증명된 25명의 환자와 배상세포가 없었던 환자들 중에서 무작위로 선택한 30예를 대조군으로 하였다. 생검 당시의 나이와 성별 그리고 MUC1, MUC2, Ki-67에 대한 면역조직화학적 염색을 시행하였다. 결과 : 바렛식도의 평균 나이 및 남자 비율은 각각 65.3±10.1세, 76.0%이였고, 대조군의 평균 나이 및 남자 비율은 각각 53.0±14.8세, 60.0%로 바렛식도의 나이가 대조군식도보다 의의있게 높았다. MUC1은 바렛식도 및 대조군 모두에서 100% 발현되었고, MUC2 발현율은 바렛식도 및 대조군에서 각각 92%, 20%이었다. Ki-67 발현율은 바렛식도 및 대조군에서 각각 80.0%, 70.0%이였고, Ki-67 발현 강도의 평균은 바렛식도 1.20±0.76, 대조군 0.77±0.57로 발현 강도에서 바렛식도가 의의있게 높았다. 결론 : 바렛식도는 원주세포만 있는 식도에서 보다 좀더 지속적인 위식도역류 등의 자극으로 생긴다. 그리고 MUC2는 주로 바렛식도에서 발현되고 세포증식능은 바렛식도에서 좀더 높으며 이는 MUC2 발현과 관련될 수 있다고 생각된다. Background/Aims: Barrett`s esophagus is characterized by the presence of metaplastic columnar epithelium with goblet cells in the distal esophagus. Barrett`s esophagus progresses through low grade dysplasia and high grade dysplasia to adenocarcinoma. We studied the patient age, the mucin gene and the proliferation activity of biopsy-proven Barrett`s esophagus and simple columnar epithelium-lined esophagus. Methods: To evaluate the mucin gene expression and proliferation activity, twenty five cases of Barrett`s esophagus and thirty cases of control esophagus were examined immunohistochemically with using the monoclonal antibodies to MUC1, MUC2 and Ki-67. Results: The Barrett`s esophagus patients were older (mean: 65.3±10.1 years) than the control patients (mean: 53.0±14.8 years). The MUC1 expression was 100% in both Barrett`s esophagus and the control esophagus. An MUC2 expression was observed in 92.0% of the Barrett`s esophagus and 20.0% of the control esophagus. The rate and intensity of the Ki-67 expression was higher in the Barrett`s esophagus (80.0%, 1.20±0.76) than that in the control esophagus (70.0%, 0.77±0.57). Conclusions: Barrett`s esophagus is a metaplastic lesion due to the more long-standing gastroesophageal reflux than that in a simple columnar epithelium-lined esophagus. The cause of increased proliferation activity in Barrett`s esophagus may be related to the MUC2 expression. (Kor J Neurogastroenterol Motil 2007;13:21-25)

      • KCI등재후보
      • KCI등재
      • 개심술(開心術)의 임상적 고찰 : 치험 200예 200 Cases

        최형호,서홍주,임영혁,김정중,배대양,이석기,임진수 조선대학교 부설 의학연구소 2002 The Medical Journal of Chosun University Vol.27 No.2

        Background and Objectives: Two hundred cases of the open heart surgery due to congenital and acquired heart disease were done using the cardiopulmonary bypass in the Department of Thoracic and Cardiovascular surgery, Chosun University Hospital from November, 1980 to June, 2001. Material and Methods: The number of congenital heart disease was 132 cases. 68 cases were acquired heart disease. 'The age of the congenital heart disease was from 22 days to 45 years. In the acquired heart disease, the age was from 14 to 72 years. Result: Congenital heart disease consisted of 113 congenital acyanotic heart disease, 19 congenital cyanotic heart disease. Corrective operation was done for congenital heart disease with 4. 5 % operative mortality. Of 68 cases acquired heart disease, 44 patients were valvular heart disease, 3 cardiac tumors, 9 ischemic heart diseases, 12 aortic dissections and etc. The operative mortality was 13%. Conclusion: The postoperative complications were appeared in 68 cases and the complications were wound infection, occipital alopecia, low cardiac output syndrome, arrhythmia, septicemia etc. The mortality after open heart surgery was 15 cases and the causes of death were low cardiac output syndrome, septicemia, respiratory failure and left ventricle rupture.

      • KCI등재
      • 대학생집단의 뇌기능 특성화 경향에 대한 연구

        최기수,윤규태,안의태,양남길,고정식,박경호 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.2

        체육학과 학생 163명과 국가대표선수 211명을 포함한 체육 전공자들과 의과대학생 282명, 문과대학생 101명, 신학전공학생 96명 그리고 간호학과 전공학생 100명, 계 953명을 대상으로 남녀 대학생들의 대뇌반구의 특성화, 편재화 경향을 시나가와 ( 品川)질문지 법을 이용하여 분석한 결과 다음과 같은 결과를 얻었다. 1. 체육과 남학생은 우뇌형 45.6%, 좌우뇌형 47.4%, 좌뇌형 7%로 나타났으며, 여학생의 경우 우뇌형 41.6%, 좌우뇌형 44.3%, 좌뇌형 14.2%로 나타났다. 2. 대표선수의 경우 우뇌형과 좌우뇌형에서 일반 체육학과 학생과 유사한 분포를 보였으나, 좌뇌형이 남자 12.9% 여자 12.6%로 남녀 고른 분포를 나타냈다. 3. 의과대학생의 경우 남학생은 우뇌형 63.5% 좌우뇌형 24.9% , 좌뇌형 11.6%인 반면, 여학생은 우뇌형 50%, 좌우뇌형 22.9%, 좌뇌형 27.1%로 나타났다.. 4. 문학은 전공하는 남녀학생과 신학을 전공하는 학생은 우뇌형, 좌우뇌형, 좌뇌형의 순으로 유사하게 나타났다. 5. 간호학전공 학생의 분포는 우뇌형42.0% 좌우뇌형 38.0% 좌뇌형 20%였다. Many Studies have demonstrated that the two hemispheres are functionally specialized in the majority of individuals, so that the left hemisphere regulates verbal-analytic cognitive abilities while the right hemisphere predominates in spatial-synthesis abilities. This research program have proceeded about the tendency of hemisphere specialization in sportsmen and variable subject classes in university. Sinagawa's questionnaire method was used as the instrument for this study . The results obtained were as follows: 1. In the physical education class(163subjects) 45.6%(male) and 41.6%(female) of the subjects were regarded as the left hemisphere dominant type, 47.4%(male) and 44.3%(female) of them were bilateral and 7%(male) and 14.2%(female) of them were regarded as left hemisphere dominant type. 2. In the representatives (mational players) group, very similar frequencies were shown except in the left hemisphere dominant type, whose percentile distributions appear as 12.9% in males and 12.6% in females. 3. Extremely higher frequency was shown in right hemisphere dominant type in the male students of medical science class : 63.5% of them were right, 24.9% were bilateral and 11.6% were left hemisphere dominant type. 4. The frequencies of the literature class also were shown very similar patterns with those of other female classes.

      • 영역분리 알고리즘을 이용한 자료의 자동 입력기법

        최길성,정혜경,신재룡,곽윤식,조기형 충북대학교 컴퓨터 정보통신 연구소 1997 컴퓨터정보통신연구 Vol.5 No.1

        In the GIS(Geographic Information System), the construction of a map-database requires vast expense and efforts. The manual and semi-automatic digitizing techniques which are generally used to make a digital map nowadays have limit to productivity, even to experts. Also, the existing methods have problems in maintaining consistent data precision by individual character of operators. In this thesis, we propose a new technique that automatically constructs a map-database by using a domain segmentation algorithm. The proposed technique minimizes the problems of the existing techniques. The reason is that it separates text and pictures domain automatically for coverages and the constructs data for each coverage.

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