년령 증가에 따른 췌장도 내분비세포 분포에 관한 조직학적 연구

최창근,이원복,라봉진 중앙대학교 의과대학 의과학연구소 1983 中央醫大誌 Vol.8 No.1

It is well known that the islet changes of pancreas could be induced by various factors, for example, obesity, hormones, pregnancy, age, etc. For the observation of the effect of age and sex, the size of the pancreatic islets and endocrine cells composing them were calculated. As an experimental animal the albino rats of Wistar strain were used. During breeding for fifty weeks, the rats were sacrificed with the interval of ten weeks and the pancreatic tissues were fixed in Bouin's solution and stained with hematoxylin and eosin, and aldehyde fuchsin and trichrome. The results were as follows : 1. At the age of fifty weeks of the male, the islets showed marked hypertrophy with peri-and intra-insular fibrosis. 2. The changes of the islets are found more earlier and severe in the male than in the female. 3. The frequency of appearance of pancreatic endocrine cells seemed not to change greatly during the increase of age.

Quality change during preservation of cultivation mushrooms, Flammulina velutipes and Agaricus bisporus

Jin-A Oh,Jong-Chun Cheong,Chan-Jung Lee,Chang-Sung Jhune,Young-Bok Yoo 한국버섯학회 2010 한국버섯학회지 Vol.8 No.4

The standard does much to improve merchantable quality, distribution efficiency and fair dealings by shipping of the standard agricultural products. Mushrooms notified as the standard are five items; Pleurotus ostreatus, Pleurotus eryngii, Flammulina velutipes, Agaricus bisporus and Ganoderma lucidum. But many farmers are suffering from a strict standards. So these standard is required modification to fit farmhouse situations. This study was carried out to investigate mushroom quality of farm shipping and quality change during preservation at various treatment. Flammulina velutipes and Agaricus bisporus preserved at different temperature( 4℃, 10℃, 20℃) to investigate quality changes. Pileus diameters of Flammulina velutipes was 67% of first grade and 33% of second grade at the early stage. After two weeks, pileus diameters was not signigicant changes; 50% of first grade, 50% of second grade at 4℃ and 50% of second grade, 50% of third grade at 10℃. Although there were no significant changes of diameter at 20℃, most of the fruit bodies were decayed. In case of Agaricus bisporus, pileus diameter was 15% of first grade, 81% of second grade and 4% of third grade at the early stage. The more storage period longed, the more the color of the fruit body was browned. But pileus diameters was not signigicant changes. Hardness and chromaticity of these mushroom was declined as time passed. Now we are carrying out more research on some mushroom’s standards for improve consumer confidence.

Label-free DNA detection with a nanogap embedded complementary metal oxide semiconductor

Kim, Chang-Hoon,Jung, Cheulhee,Lee, Kyung-Bok,Park, Hyun Gyu,Choi, Yang-Kyu IOP Pub 2011 Nanotechnology Vol.22 No.13

<P>A nanogap embedded complementary metal oxide semiconductor (NeCMOS) is demonstrated as a proof-of-concept for label-free detection of DNA sequence. When a partially carved nanogap between a gate and a silicon channel is filled with charged biomolecules, the gate dielectric constant and charges are changed. When the gate oxide thickness reduces, the threshold voltage is significantly affected by a change of the charges, whereas it is scarcely influenced by a change of the dielectric constant. In the case of DNA, those two factors act on the threshold voltage oppositely in an n-channel NeCMOS but collaboratively in a p-channel NeCMOS because of the negative charges of DNA. Hence, a p-channel NeCMOS with a thin gate oxide is more attractive for DNA detection because it enhances the shift of threshold voltage; that is, it improves the sensitivity of DNA detection. In addition, the shift of threshold voltage according to the nanogap length is also investigated and the longer nanogap shows more shift of the threshold voltage.</P>

제올라이트 분말도와 치환율에 따른 시멘트모르타르의 활성도 지수 평가에 관한 실험적 연구

윤창복 ( Yoon Chang Bok ),박장현 ( Park Jang Hyun ),이한승 ( Lee Han Seung ) 한국구조물진단유지관리공학회 2019 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.23 No.1

This research and development analysis provides numerical analysis techniques that can be used conveniently to determining the safety of the current state and to predict the stability in the future. It also seeks to present algorithms of back analysis to develop unified management system for control, prediction, coordination, and information modeling that can reasonably handle appropriate responses to structural behavior at project sites and design changes.

만성 췌장염에 의한 십이지장 협착 1예

서백종,장기육,박용근,채현석,한석원,이창돈,정인식,차상복,박두호 대한내과학회 1997 대한내과학회지 Vol.53 No.3S

저자들은 만성췌장염환자에서 지속적인 오심과 구토를 주소로 내원하여 십이지장협착으로 진단된 1예를 경험하였기에 보고하는 바이다. Duodenal stenosis resulting from fibroinflammatory process is a rare complication of chronic pancreatitis. The mechanism of duodenal stenosis seems to be related to ischemia and edema caused by persistent inflammation, which results in irreversible change of duodenal wall structure. We experienced a chronic alcoholic male patient with duodenal stenosis who had a history of choledochojejunostomy to relieve distal bile duct stenosis several years ago. He had suffered persistent postprandial nausea and vomiting for several months. Barium study of upper gastrointestinal tract and repeated endoscopy show narrowing lumen of duodenum with coarse nodular surface due to reactive inflammatory change.

Effects of viscoelastic material on the corneal endothelial cells in trabeculectomy with adjunctive mitomycin-C

Dong Bin Shin,Seung Bok Lee,Chang Sik Kim 대한안과학회 2003 Korean Journal of Ophthalmology Vol.17 No.2

We evaluated the change of corneal endothelium after trabeculectomy with mitomycin-C soaking (0.2 mg/ml, 2.4 ± 1.2 minutes) and the effect of viscoelastic material in reducing this change. In randomly selected cases, 0.05 ml of sodium hyaluronate (Healon??) was injected into anterior chamber (Healon group, n = 20), and same amount of balanced salt solution was injected in the other eyes (Control, n = 18) at the beginning of surgery. There were no differences in clinical variables and specular microscopy result between 2 groups before surgery. After surgery, the change of endothelial cells were significantly reduced in Healon group (cell density; -2.5 ± 1.6%, variability of cell area; 5.8 ± 2.5%, and percentage of hexagonal cell; -2.2 ± 0.7%) compared to control group (-7.7 ± 6.0%, 8.9 ± 4.4%, and -4.8 ± 3.5% respectively, p < 0.01). In trabeculectomy with mitomycin-C, the damage to the corneal endothelium was reduced significantly by injecting the viscoelastic material without significant complication.

투시장치의 화질관리 실태 조사

이성길,김영근,김창복 광주보건대학 2004 論文集 Vol.29 No.-

It is important to control resolution for maintenance of good image quality in fluoroscopic unit. This study is to analyze current situation on control of image quality in fluoroscopic unit. Between the sixth and the twenty eighth March 2003, 77 fluoroscopic units in 40 hospitals in Seoul and Kyung-gi area were tested with fluoroscopic phantom(CDRH phantom, Nuclear associates, USA) and image quality test tool including hight contrast resolution patterns and low contrast objects. We exposed radiation in condition of colon study, and then counted the number of patterns on monitor, printed spot film, and printed abdominal film. In the test on monitor, suitable unit within standard number in hight contrast and low contrast test were 68(88%), 49(64%), respectively, and in the test on printed spot film 73(95%), 67(87%), respectively. The cases within standard number in hight contrast and low contrast test on all the two monitor and printed spot film were 44(57%), 65(84%), respectively. Thradiation was exposed from 100 to 120Kvp in fluoroscopy, and spot radiography 80 to 110Kvp mainly. In conclusion, it is necessary that image quality control is done continuously by standard of image quality control suitable for current situation.

都市型 有料老人福祉施設의 動向과 建築計劃的 提案에 關한 硏究

이진혁,임창복 대한건축학회 2005 대한건축학회논문집 Vol.21 No.3

Housing is one of the most important issues in the consideration of social welfare for the elderly. The purpose of this study is to offer basic research data of planning and to cope with coming aged society through architectural design proposal of proper urban type user-charged residential facilities to live continuously where they are. As a result, 1. as selecting locations for residential facilities, elderly social welfare facilities need to be located in 10 minutes on foot or by vehicle so that elderly people can access easily and to keep close connection between facilities. 2. mixed-use development is needed, 3. the type of facility is would be sheltered housing, 4. small scale facility management in urban go to local govern institution or non profit private organization for stability. 5. building layout would rather be better in one building with vertical function separation, and atrium layout which is dominate in Europe and Japan and, offer strong community need to be taken into consideration. 6. the preference of room size by survey and research is 7-9(pyung) for single and 11-17(pyung) for couple, 7. a building of 50 dwelling units or so with 2-3 stories is ideal from a caregiving and management perspective in urban area.

등교 거부 청소년의 환경 및 심리 상태

이소희,노경선,김창기,고복자 대한신경정신의학회 2000 신경정신의학 Vol.39 No.6

연구목적 : 본 연구는 다양한 원인에 의해서 일어난다고 알려져 있는 등교거부 청소년의 가족, 학교 생활 및 심리 상태를 평가하여 정상 대조군의 각 변이들과 비교하고자 하였다 방 법 : 1998년 5월부터 1999년 1월까지 본원을 방문한 등교거부 청소년 24명과 정상대조군을 대상으로 Parent Bonding Instrument, Index of Marital Satisfaction, Family Environment Scale을 사용하여 가족 기능을 평가하였고, 저자들이 고안한 척도를 사용하여 학업, 또래 교사와의 관계에서의 스트레스를 평가하였으며, Fear of Survey Schedule for Children-Revised(the Fear of Failure and Criticism Factor), Center for Epidemiological Studies-Depression를 사용하여 두려움과 우울의 정도를 측정하였다. 결 과 : 등교거부자들을 비거부자보다 더 가족이 독립성과 성취을 추구한다고 느끼는 것으로 나타났고, 학교 관련 스트레스의 정도는 두 군간에 유의한 차이가 없었고, 우울 정도가 유의하게 더 높았다. 또 등교거부자는 학교에 가는 것과 방과 후 학교에 남는 것을 비거부자보다 유의하게 더 두려워 하고, 비거부자는 등교거부자보다 성적이 낮은 것과 시험에 실패하는 것을 유의하게 더 두려워 한다는 것을 알 수 있었다. 결 론 : 저자들은 본 연구 결과를 통하여 등교거부자들이 어릴 때부터 과잉보호를 받거나 엄격한 부모에게서 성취 강요와 과잉 기대를 받아서 자존감과 유능감이 저하되어 결국 부모가 독립성과 성취를 요구하는 것으로 간주하게 되는 기전을 제시하고, 국내의 일반 청소년이 등교거부자 못지 않게 학교 스트레스가 많을 가능성과 등교거부자는 학교회피 기간이 길어지면서 학업성취 등을 포기함에 따라 오히려 스트레스가 높지 않을 가능성을 제시하였다. Objectives : School refusal can result from various causes ; temperament, familial influences, And school experiences have been identified. This study was to compare family, school and psychological functioning in school-refusing adolescents and non-refusing ones. Methods : Twenty-four school refusing outpatients aged 13-17 years were evaluated from May, 1998 to January, 1999. They completed self-report questionnaires, including parent Bonding Instrument, Family Environment Scale, Index of Marital Satisfaction, Scales for School-related Distress, Center-for Epidemiological Studies-Depression, The Failure and Criticism Factor of Fear Survey Schedule from Children-revised. Their scores were compared with nonrefusers. Results : The results were as follows : 1) School refusers perceived their family as more independence and achievement-oriented than nonrefusers. 2) School refusers did not differ significantly from nonrefusers in school-related distress. 3) School refusers had more depression than nonrefusers. 4) School refusers claimed more fear of having to go to school, and having to stay after school than nonrefusers. On the other hand, nonrefusers expressed greater apprehension about situations such as Being called on by the teacher, Getting poor grades, Failing a test, and Taking a test. Conclusion : The results suggested two postulated mechanisms of school refusals(overprotection and demanding of independence of parents)and possible causes of each result were discussed.

스퍼터로 제작된 WO₃박막의 CMP 광역평탄화 특성

이우선,고필주,최권우,정수복,최창주 조선대학교 에너지.자원신기술연구소 2003 에너지·자원신기술연구소 논문지 Vol.25 No.2

Chemical mechanical polishing (CMP) process has been widely used to planarize dielectric layers, which can be applied to the integrated circuits for sub-micron technology. Despite the increased use of CMP process, it is difficult to accomplish the global planarization of in the defect-free inter-level dielectrics (ILD). We investigated the performance of WO₃ CMP used silica slurry, ceria slurry, tungsten slurry. In this paper, the effects of addition oxidizer on the WO₃ CMP characteristics were investigated to obtain the higher removal rate and lower non-uniformity.