임상치관연장 술식의 선택시 고려사항

조은혜,고경호,허윤혁,조리라,박찬진,Jo, Eun-Hye,Ko, Kyung-Ho,Huh, Yoon-Hyuk,Cho, Lee-Ra,Park, Chan-Jin 대한치과보철학회 2018 대한치과보철학회지 Vol.56 No.2

Clinical crown lengthening procedure would be an effective method for overcoming adverse clinical condition such as short abutment length. There are three kinds of methods in clinical crown lengthening, those are, surgical crown lengthening, orthodontic extrusion and surgical extrusion. Clinicians have to try their best to choose a proper method among those for favorable results. This report aims to review the considerations in each method with various cases and to suggest a decision flow for appropriate selection. 임상치관이 짧아 보철 수복이 어려운 경우 임상치관연장술이 효과적인 치료법이 될 수 있다. 임상치관 연장을 위한 술식에는 수술적 치관연장술, 교정적 정출술, 외과적 정출술이 있는데, 임상상황을 고려하여 최선의 선택을 해야 한다. 수술적 방법과 교정적 방법을 선택할 때, 적절한 고려사항과 주의점에 대해 여러 증례와 함께 보고하고 결정흐름도를 제시하고자 한다.

BARODON^® 에 의한 Human Gastric Adenocarcinoma AGS 세포고사

조은혜,최수일,김수림,조성대,안남식,정지원,양세란,박준석,황재웅,박용호,이영순,강경선,Jo Eun-Hye,Choi Soo-Il,Kim Soo-Rim,Cho Sung-Dae,Ahn Nam-Shic,Jung Ji-Won,Yang Se-Ran,Park Joon-Suk,Hwang Jae-Woong,Park Yong-Ho,Lee Yong-Soon,Kang Kyung 한국독성학회 2005 Toxicological Research Vol.21 No.2

[ $BARODON^{(R)}$ ] is a multi-purpose, high functional alkali solution made by mixing and liquid-ionizing silicon, calcium, sodium, borax, organic carbon chemicals and silver. In this study, we have investigated the apoptotic potential and mechanistic insights of $BARODON^{(R)}$ in human gastric cancer cell line (AGS cells). In MTT assay, $BARODON^{(R)}$ reduced cell viability in AGS cells. Morphological features of apoptosis with marked cytoplasmic vacuolation and appearance of apoptotic peaks in flow cytometry were observed in AGS cells with$BARODON^{(R)}$ treatment. In addition, $BARODON^{(R)}$ induced apoptosis of stomach cancer cell is related to bax up-regulation, caspase 7 protease activation and subsequent cleavage of poly (ADP-ribose) polymerase (PARP). These results suggest that BARODON can induce the apoptosis of AGS cells through modulation of bcl-2 family and the activation of intrinsic caspase cascades, indicating that it is potentially useful as a anti-cancer agent.

나노물질의 세포독성 평가법으로 Colony Forming Efficiency Assay에 대한 검증연구

조은혜,이재우,박선영,김필제,최경희,엄익춘,Jo, Eunhye,Lee, Jaewoo,Park, Sun-Young,Kim, Pilje,Choi, Kyunghee,Eom, Igchun 한국환경보건학회 2015 한국환경보건학회지 Vol.41 No.1

Objectives: The cytotoxcities of Au, Ag, SWCNT, $SiO_2$, and ZnO nanomaterials were evaluated in order to assess their potential toxicological effects in in vitro cell models using colony forming efficiency (CFE) assay. Methods: The CFE assay of the test materials was carried out on Hep G2 cells. The size distribution of nanomaterials was studied by transmission electron microscopy (TEM). Changes in cell viability after treatment with a toxicant will result in a decreased number of colonies formed in comparison to solvent. Results: The TEM images show that all the particles except SWCNT and ZnO can be considered approximately spherical. The gold and $SiO_2$ nanoparticles show no response (no toxicity) in concentration response experiments. A statistically significant toxic effect was found in Hep G2 cells treated with Ag, SWCNT and ZnO nanomaterials. Conclusion: In this study, we considered CFE assay to be a promising test for screening studies for cytotoxicity with physicochemical analysis.

비특이 면역증강제 BARODON^ⓡ의 항원성시험

조은혜,조성대,안남식,정지원,양세란,박준석,박기수,홍인선,서민수,이영순,강경선,Jo, Eun-hye,Cho, Sung-dae,Ahn, Nam-shik,Jung, Ji-won,Yang, Se-ran,Park, Joon-suk,Park, Ki-su,Hong, In-sun,Seo, Min-su,Tiep, Nguyeu Ba,Lee, Yong-soon,Kang, K 대한수의학회 2003 大韓獸醫學會誌 Vol.43 No.2

The antigenicity of nonspecific immunostimulator BARODON$^{(R)}$, a newly developed drug, was investigated by tests for passive cutaneous anaphylaxis (PCA) and active systemic anaphylaxis (ASA) in mice and guinea pigs. In ASA test using guinea pigs, there were no significant clinical symptoms in all individuals of low(0.3%) and high(3%) dose of both groups treated with only BARODON$^{(R)}$ and cotreated with BARODON$^{(R)}$ and adjuvant group. In PCA test, blue spots of Evan's were observed from $2^6$ to $2^{10}$ in homologous group and from $2^2{\sim}2^5$ dilution rate in heterologous group of BSA treated positive control group. However, intradermal sensitization with antiserum obtained from low (0.3%) and high (3%) dose of BARODON$^{(R)}$ only treatment group and treated-with-adjuvant group, followed by intravenous injection of respective antigen and Evan's blue mixture (1:1) showed no blue spot observed. In conclusion, BARODON$^{(R)}$, as showed in ASA and PCA test, did not cause anaphylatic shock when treated 3 and 10 times higher than clinically intended dose, nor induce IgE, so that might not have antigenic properties in mice and guinea pigs.

전치부의 심한 마모를 동반한 교합고경 감소 환자에서 상악의 double crown retained RPD와 하악의 conventional RPD를 이용한 치료: 증례보고

조은혜,김미자,안병근,강진한,신미란,Jo, Eun-Hye,Kim, Mi-Ja,An, Byeong-Geun,Gang, Jin-Han,Sin, Mi-Ran 대한심미치과학회 2007 Journal of the Korean Academy of Esthetic Dentistr Vol.16 No.2

오리맛집 - 낙원가든

조은혜,Jo, Eun-Hye 한국오리협회 2015 오리마을 Vol.144 No.-

통과의례의 관점에서 본 창세기 22:1-19의 의미

조은혜(Eun-Hye Jo) 연세대학교 신과대학(연합신학대학원) 2022 신학논단 Vol.107 No.-

이 논문은 창세기 22:1-19를 통과의례의 관점에서 분석함으로써 본문의 경험이 아브라함에게 갖는 의미를 탐구하는 데 목적이 있다. 창 22:1-19의 구조는 통과의례의 단계에 따라 크게 분리와 전이, 통합의 세 부분으로 나눌 수 있다. 분리(1-5절) 부분에서 아브라함은 이삭을 번제로 바치라는 하나님의 명령을 듣고 자신의 기존 세계에서 공간적, 상징적으로 이탈한다. 전이(6-14절)에서 아브라함은 하나님이 지정한 산에 올라 이삭의 제사를 준비하며 원형적, 생애사적 상징의 측면에서 죽음을 함축하는 여러 행위를 통해 상징적 죽음을 맞는다. 그리고 경계성에 의해 그의 삶에 있던 약속의 내부와 외부, 단절하는 자와 단절되는 자의 대립이 소멸되는 체험을 한다. 통합(15-19절) 부분에서 아브라함은 하나님 사자의 소리 속에 전 존재가 잠기는 가운데 갱신된 약속을 받으며 만민의 복의 근원이 되는 존재의 전환에 이른다. 아브라함은 창 12:3에서 모든 민족의 복의 근원이 되는 축복을 받았지만, 이삭과 그 후손을 약속의 내부자로 확정하는 과정에서 관계의 단절을 거듭하며 약속 외부자의 고통을 초래해 왔다. 창22:1-19에서 아브라함은 약속 내부와 외부의 대립 소멸과 함께 죽음과 재생을 거침으로써 이러한 결함을 해결하고 온 세상의 복의 근원으로서 확장된 정체성을 완성한다. 약속의 후손인 이삭을 제물로 바쳐야 하는 역설적 상황과 인물과 사물, 공간의 상징성, 시각과 촉각, 청각 등 다양한 감각을 활용한 묘사를 통해 본문은 이러한 의미를 효과적으로 형성한다. This article intends to shed light on the meaning and value of genesis 22:1-19 from the perspective of the rite of passage. Gen. 22:1-19 is divided into three parts according to the stages of the rite of passage — separation, transition, and incorporation. In the part of separation (vv. 1-5), Abraham departs spatially and symbolically from his existing world in obedience to God’s command to sacrifice Isaac as a burnt offering. In the part of transition (vv. 6-14), he undergoes a symbolic death through various acts which imply death in terms of archetypal and life-historical symbols as prepares the sacrifice of Isaac on the mountain chosen by God. And he experiences the destruction of the opposition between the inside and outside of God’s promise, and between the person who cut off and the person who is cut off due to the liminality. Finally, in the part of incorporation (vv. 15-19), Abraham receives the renewed promise while his entire being is immersed in the voice of God’s messenger, and transforms into the being that is the source of blessings for all people. As a result of this interpretation, we can find the function of Gen. 22:1-19 in the Abraham narrative of Genesis. Though Abraham received the blessing that he becomes the source of all nations in Gen. 12:3, he repeatedly severed the relationship and caused the suffering of outsiders of the promise in the process of confirming Isaac and his descendants as insiders of the promise. In Gen 22:1-19, He resolves this deficiency and completes his extended identity as a source of blessing for the whole world by going through death and rebirth with the dissolution of opposition inside and outside of the promise. This narrative effectively forms this meaning through the paradoxical situation of sacrificing Isaac, the descendant of the promise, and the symbols of people, objects, and spaces, and the description using various senses such as sight, touch, and hearing.

비교가능성이 기업단위의 주가폭락에 미치는 영향

조은혜 ( Eunhye Jo ),문해원 ( Haewon Moon ),최영수 ( Young Soo Choi ) 한국회계학회 2015 회계학연구 Vol.40 No.4

회계정보의 비교가능성이 클수록 기업 고유 정보의 양과 질이 증대되어 악재가 기업내부에 누적될 가능성이 감소한다. 따라서 비교가능성의 증가는 악재의 누적으로 인한 갑작스러운 주가폭락의 가능성을 낮출 수 있다. 이에 따라 본 연구는 회계정보의 비교가능성이 기업단위의 주가폭락을 감소시키는지에 대해 분석하였다. 또한 외국인투자자가 비교가 능성을 향상시키는 역할을 한다는 선행연구(Fang et al. 2015)에 따라 비교가능성이 주가폭락을 감소시키는 효과가 외국인지분율에 따라 차이가 있는지를 살펴보았다. De Franco et al.(2011)과 Francis et al.(2014)의 비교가능성 측정치와 Hutton et al.(2009)의 주가폭락 측정치를 이용하여 2005년부터 2012년까지 유가증권에 상장된 2,317개의 관측치를 대상으로 분석한 결과 비교가능성이 클수록 미래 주가폭락 가능성이 낮았다. 그리고 이러한 관계는 외국인지분율이 높은 기업에서 더 강하게 나타났다. 이를 통해 비교가능성이 기업수준의 주가폭락을 감소시킴으로써 자본시장의 건전성 및 효율성을 증진시키는 기능을 수행함을 알 수 있다. 더불어 외국인지분율이 비교가능성의 효과를 강화시키는 역할을 수행함을 확인하였다. Accounting information plays an important role for the functioning of an efficient capital market(Bushman and Smith 2001; Healy and Palepu 2001; Lambert et al. 2007). The market participants make their economic decisions about a firm using various information sources including financial statements and analysts`` reports. However, despite of making decisions based on the relevant firm information, investors often suffer a terrific loss due to a sudden stock price crash of the firm. This study examines what are the determinants of the radical price crash and whether financial statement comparability impacts on stock price crash risk. The firm-specific stock price crash is a phenomenon that stock price of a firm sharply declines at the point when the accumulated negative firm-specific information crossed a tipping point suddenly comes out to the market in one fell swoop(Hutton et al. 2009). Several recent studies support that firm-specific stock price crash is caused by the internal factors such as CEO overconfidence, opacity of accounting information and aggressive accounting treatment as well as the external factors such as analysts`` optimistic forecasts and opportunistic behaviour of institutional investors (Hutton et al. 2009; Kim and Zhang 2014; Kim, Li and Li 2014; Kim, Wang and Zhang 2014; Callen and Fang 2013; Xu et al. 2013). Hiding firm``s bad news from investors`` view is possible due to information asymmetry between managers and outside investors. According to the agency theory, managers have superior information to outside investors regarding the firm``s current situations and future prospects (Jensen and Meckling 1976), so that managers can disclose their private information strategically. Graham et al.(2005) and Kothari et al.(2009) find that managers have an incentive to delay the disclosure of bad news, with concern that such disclosures can damage their compensation and position. Managers also seem to delay the disclosure of negative firm-specific news with optimistic belief that firm``s financial condition would become better in the near future. Thus, if information asymmetry between managers and outside investors decreases, managers`` strategic behavior to delay their bad news would also decrease. Comparability of accounting information is a qualitative characteristic that enables users of financial statements to identify similarities in and differences between two sets of economic phenomena. Financial statement comparability across firms and time is underscored because it facilitates the efficient allocation of capital by increasing the overall quantity and quality of information available to investors and also by lowering the cost of acquiring information(De Franco et al. 2011; Kang et al. 2013; Choi et al. 2014). The improved quantity and quality of accounting information to outside users then can lead to an decrease in information asymmetry (Diamond and Verrecchia 1991; Kim and Verrecchia 1994; Gow et al. 2011). As a result, comparability of accounting information may restrict manager``s attempt to delay the disclosure of bad news so that firm-level crash risk may also decrease. Prior studies show that foreign investors, particularly foreign institutional investors, play an important role in the improvement of comparability in firms`` financial statements by actively involving in the firms`` financial reporting process(Fang et al. 2015). Foreign investors can affect firms`` operating activity, reporting behaviour and value, by selling shares and/or by using their voting rights to intervene in management. They also can play a direct role in altering firms`` financial reporting practices, due to their independent positions and lack of conflicts of interest. As a result, the comparability of financial statements can be promoted by a market force of foreign institutional investors. We therefore conjecture that the expected negative relationship between comparability and stock price crash risk would be more pronounced by larger foreign institutional ownership. This study uses 2,317 firm-year observations listed on Korea Stock Exchange from 2005 to 2012. The comparability measures are based on De Franco et al.(2011) and Francis et al.(2014), while the stock price crash measure is based on Hutton et al.(2009). Our findings are as follow: First, consistent with our expectations, we establish that comparability is significantly and negatively associated with stock price crash risk. Second, we show that the negative relationship between comparability and crash risk is pronounced for firms with higher foreign ownership. These results are consistent with our expectations that higher comparability mitigates information asymmetry, managers`` incentives to delay the disclosure of bad news, and eventually the likelihood of stock crash. Moreover, foreign ownership seems to play a role as a catalyst in the relationship between comparability and stock price crash risk. The study has several contributions to the body of research on comparability, stock price crash and foreign ownership. First, we adds to the growing body of comparability literature, by showing the importance of comparability in stock markets. Second, to our best knowledge, this is one of few studies that focuses on the determinants of firm-level stock crash risk rather than macro economy-level stock crash risk. Third, we extends foreign ownership research, by examining its catalytic role in the relationship between financial statements and stock markets.

아토피용 스테로이드 연고의 사용자 경험(UX)향상을 위한 디자인 개발

조은혜(Jo, Eunhea),오인균(Oh, Inkyun) 인제대학교 디자인연구소 2016 Journal of Integrated Design Research (JIDR) Vol.15 No.1

연구배경 : 현재 아토피환자의 치료법으로 스테로이드 연고제가 가장 널리 이용되고 있다. 이 연고는 부작용의 위험이 있기 때문에 약의 강도와 제제 종류를 고려하여 사용해야 하지만, 실제 사용 환경에서는 지키기가 어렵다. 따라서 본 연구는 사용자 경험에 대한 직접 관찰을 통해서 스테로이드제 연고를 안전하게 사용할 수 있도록 디자인을 개발하였다. 연구방법 : 더블 다이아몬드 프로세스를 바탕으로 문헌조사방법과 질적연구방법을 적용하였다. 구체적으로는 페르소나 설정, 사용자 스토리, 고객여정지도, 상황기반 모델링(CBBP: Context Based Activity Modeling)를 통해 문제점을 발견하고, 이를 해결할 아이디어를 도출한 뒤 디자인 개발에 적용하였다. 연구결과 : 총 3가지(①대용량 크기, ②사용법, ③사용 중 연고 교체)의 문제점을 도출하였다. 이러한 문제점은 용기 디자인을 1회용 소용량으로 다시 디자인하고 전체 패키지에 등급별 연고와 면봉을 첨부하여 해결하였다. 용기디자인은 물방울 형상을 적용하였고, 아토피의 붉은 증상을 연상시키는 빨강색을 메인 컬러로 설정하였다. 결론 : 본 연구를 통해서 사용자의 경험상 일어나는 문제를 해결한 디자인을 최종적으로 도출하였다. 이는 관련제품에 대한 구체적이고 적극적인 해결방안을 모색하였다는 의의를 가지고 있으며, 본 연구를 바탕으로 관련 사용자 경험 연구의 확대를 기대한다. Background : Recently, treatment of patients with atopic dermatitis is under intensive steroid ointment. This drug should be used with extreme care because of side effects. However, it is difficult to keep them in the real life. Therefore, this study was designed to develop a steroid ointment can be used safely by direct observation for the user experience. Methods : The researchers applied a qualitative research method literature research methods based on the double diamond process. The researchers found the problem through the personas, user stories, the customer journey map, CBBP(Context Based Activity Modeling). And it presents a solution based on this. Result : The problem with all three (①large size bottle, ②use amount, ③replacement of ointments used) were derived. These problems were solved by redesigning to the disposable small size. And it was attached to the package by rating ointment with a cotton swab. vessels were applied a water drop shape, and set the red reminiscent of the symptoms of atopic red as the main color. Conclusion : This study was designed to eventually lead to solving the problem of the user experience takes place through. This design development has a meaning is sought for a specific, positive solution to the product, it is expected to expand in the User Experience research on the basis of this study.

기업설명회가 미래이익의 정보성에 미치는 영향

조은혜(Eunhye Jo) 대한경영학회 2016 大韓經營學會誌 Vol.29 No.6