악취관리지역의 운영성과와 체감대기환경개선방안에 관한 고찰 : 인천지역을 중심으로

박찬진 한국대기환경학회 2010 한국대기환경학회 학술대회논문집 Vol.2010 No.5월

무당개구리의 번식생태

박찬진,반영호,계명찬 한국양서·파충류학회 2010 한국양서·파충류학회 학술대회 Vol.2010 No.1

고혈압환자에서 Verapamil 과 Propranolol 이 기관내 삽관에 의한 혈역학 변동에 미치는 영향

박찬진,하인호,유경연,채동훈 대한마취과학회 1990 Korean Journal of Anesthesiology Vol.23 No.3

Laryngoscopy and endotracheal intubation in patients undergoing general anesthesia causes hypertension and tachycardia with concomitant increases in plasma catecholamine concentration. These transient stress responses are greatly exaggerated in patients with hypertension and cardiovascular disease and can lead to cardiac arrhythmia, pulmonary edema, cardiac failure and cerebral hemorrhage. Therefore, several attempts have been made to attenuate the hypertensive and tachycardiac responses, but none have been satisfactory. This study was designed to evaluate verapamil or propranolol as a valuable adjuvant in attenuating hemodynamic responses to tracheal intubation in 53 patients with hypertension. They were randomly divided into three groups according to premedication used. Group 1 (n=19) was without pretreatment, and group 2 (n=18) and group 3 (n=16) were pretreated with verapamil (0.1 mg/kg) iv and verapamil (0. 1 mg/kg)-propranolol (0.01 mg/kg) mixture iv, respectively, just prior to the intubation. Mean arterial pressure (MAP) and heart rate (HR) were measured, just prior to intubation (baseline), after induction, and at 1, 2, 3, 4, 5 and 7 minutes following intubation. The results were as follows. 1) In the control group. tracheal intubation produced increases in MAP (27% average increase from baseline) and heart rate (31% increase) at one minute after the procedure. 2) In group 2, verapamil abolished pressor response to tracheal intubation, but did not affect tachycardiac responses. 3) In group 3, the verapamil-propranolol mixture attenuated both pressor and tachycardiac responses to tracheal intubation. 4) The rate-pressure product increased after tracheal intubation by 61% and 31% in group 1 and group 2, respectively, but it remained unchanged in group 3. These findings suggest that intravenous verapamil-propranolol mixture is a valuable adjuvant in attenuating hypertensive and tachyeardiac responses to tracheal intubation.

Propofol 정주시 혈관통에 대한 Lidocaine 과 냉각정주법의 효과

박찬진,김원태,이철승,최준석 대한마취과학회 1993 Korean Journal of Anesthesiology Vol.26 No.2

Propofol containing solvents such as soybean oil, egg phosphatide, glycerol, is known to arouse pain on intravenous injection in most patients. The study was undertaken to evaluate the efficacy of the two methods in preventing pain during injection of propofol on induction of anesthesia. Patients were allocated randomly into three groups. The one to receive unmodified propofol as control, the other to have injection of propofol with lidocaine added O.l mg/kg and another to have administration of propofol cooled in 0∼4℃. The results showed that propofol with lidocaine mixed and propofol cooled in 0∼4℃ significantly lowered the incidence of pain during the intravenous injection of the drug and that addition of lidocaine and cooling had no untoward effect on the cardiovascular system.

Pheno1에 의한 요부교감신경절 차단

박찬진,정창영,문화영 대한통증학회 1988 The Korean Journal of Pain Vol.1 No.1

Phenol sympathetic block is valuable for the treatment of ischemic pain, gangrene, intermittent claudication, Paget's disease of the bone and pain associated with pancreatitis, pancreatic carcinoma, etc. The author has experienced a case of successful lumber sympathetic block using 7% phenol under fluoroscopy and given to a patient with Buerger's disease who had severe pain and ulceration of the right great toe for several years. After the sympathetic block, 2 epidural blocks with 2.5% bupivacaine were done in order to augment the effects of this sympathetic block. Subsidence of rest pain, increase in walking distance from under 100 M to over 500 M and circulatory improvement of the affected limb were observed. Improvement of circulation was confirmed by strain gauge plethysmography.

내분비계장애물질 대체소재의 안전성

박찬진,김웅,계명찬 한국환경생물학회 2015 환경생물 : 환경생물학회지 Vol.33 No.4

Endocirne disruptors (EDs) can cause fertility decrease, developmental disorder, and even cancer in animals. Until 90’s, EDs were used in various synthetic products including paints, coatings, detergents, plastics, and plasticizers. Currently, in several countries, the production, trade and use of EDs or EDs-suspected chemicals have been regulated while activity to screen the alternatives for EDs including bisphenol-A, phthalate and nonylphenol is active. Although various toxicity test method was developed and applied for screening of alternatives, however, the safety of alternatives has been not fully demonstrated. Some alternatives have high structural similarity with existing EDs, raising the possible risk of endocrine disruption by alternatives. In an effort to develop the safe alternatives, we reviewed the effects of EDs such as bisphenol-A, phthalates, nonylphenol and their substituents. In addition, in-silico analysis for endocrine disrupting activities of some alternatives was presented.

하천복원용 콘크리트 소재가 무당개구리 (Bombina orientalis) 배아에 미치는 영향

박찬진,안홍규,계명찬,이태형,Park, Chan Jin,Ahn, Hong Kyu,Gye, Myung Chan,Lee, Tae Hyeong 응용생태공학회 2015 Ecology and resilient infrastructure Vol.2 No.2

독성 소재를 활용하여 하천생태복원 사업을 추진할 경우, 수생 생물이 직접적으로 독성물질에 노출되어 다양한 생물학적 문제를 야기할 수 있다. 따라서, 본 연구에서는 하천사업에 활용되는 콘크리트 소재의 독성을 분석하기 위해 한국산 무당개구리(Bombina orientalis)배아를 이용하여 생존율과 기형발생률 측면에서 발생독성 분석을 수행하였다. 콘크리트 바인더들의 독성을 평가한 결과, 무당개구리 배아의 생존율은 대조군 (control), 식물성 폴리우레탄(P1), 우레탄(P2), 시멘트(C) 실험군에서 각각 100%, 94-95%, 66-89%, 0%로 나타났다. 기형발생률은 대조군, P1, P2, C 실험군에서 각각 10.5%, 5.3-10.5%, 26.3-27.8%, 35.7%로 나타났다. 시멘트의 독성이 가장 강하게 나타났으며, 상대적으로 식물성 폴리우레탄의 독성이 가장 약한 것으로 나타났다. 또한, 충분한 양생시간을 가짐으로써 용출되는 독성물질이 저감되는 것을 확인하였다. 이상의 결과들로서 시멘트와 폴리우레탄은 양서류의 초기발생을 저해하는 것이 확인되었다. 본 연구는 하천복원을 위한 소재의 선택에 있어 생물학적 안전성을 검토하는 것이 매우 중요하며, 친환경 소재 및 친환경 공정 선택의 중요성을 보여준다. Various adverse effects can occur due to direct exposure from toxic substances when toxic materials are used to restore river ecosystems. Thus, this study performed analysis on the development of toxicity in terms of survival and abnormality rates using embryos of Bombina orientalis living in Korea to analyze the toxicity of materials used in the river projects. The results showed that the toxicity in cement (C group) was the strongest whereas the toxicity in plant-based polyurethane (P1 group) was the weakest. Survival rates of B. orientalis embryos were 100%, 94 - 95%, 66 - 89% and 0% in control, P1, polyurethane (P2) and C groups, respectively. Abnormalities of embryos were 10.5%, 5.3 - 10.5%, 26.3 - 27.8% and 35.7% in control, P1, P2 and C groups, respectively. Furthermore, we verified that having a sufficient curing time reduced toxic substances that were extracted. The above result suggest that cement and polyurethane hamper the early development of amphibians. In conclusion, it is highly important to review biological safety with respect to the selection of materials used to restore rivers. This study shows the importance of the selection of eco-friendly materials and processes.

매립지의 메탄가스 자원화와 악취 특성

박찬진 한국냄새환경학회 2012 실내환경 및 냄새 학회지 Vol.11 No.4

The characteristics of odor generation with the production of resources by utilization of methane gases in landfill sites was investigated, and the effect of making resources with landfill gases on the reduction of odor was analyzed in recent years. The greenhouse gas was estimated to reduce from the range of 1,334,940~209,875 tCO₂e with the period of 2008~2017, and the effective odor was diminished with considerable amount. The more effective methods of odor removal with the utilization of waste gases were estimated by studies of similar cases to acquire standard methods of making energy resources by waste gases.

인천국제공항 전용 고속도로 주변 환경오염원 실태 조사

박찬진,여운호,전성택 한국환경관리학회 2004 한국환경관리학회 학술연구발표회 논문초록집 Vol.2004 No.7

Propranolol 이 Ether, Halothane 및 Penthrane 마취시 혈압 및 맥박에 미치는 영향

박찬진,임웅모,하인호 대한마취과학회 1982 Korean Journal of Anesthesiology Vol.15 No.1

Midazolam maleate, a water soluble banzodiazepine unlike diazepam, was synthetized by Walser and Fryer in 1975. In order to ealuate the effectiveness as an induction agent for general anesthesia, 22 elective surgical patients belonging to ASA classification 1 and 2 were selected. And ten patients (male 7, female 3, average 33.5 years old) were induced with midazolam maleate 0.2mg/kg and twelve patients (mdale 7, female 5, average 32.5 years old) with diazepam 0.3mg/kg. The results were summarized as follows. 1) Anesthesia was induced in all of midazolam group by one intravenous injection, but only 6 patients of diazepam group could induced by one injection and the other 6 patients needed 2 or more injections. 2) The changes of blood pressure and pulse rate after induction and intubation were almost similar in the two groups, but greater individual variation was seen in diazepam group. 3) A buring sensation following intravenous injection was noted in 11 cases of diazepam group, but none in midazolam group and no phlebitis in either group. From the above results, diazepam and midazolam are almost similar in nature but midazolam is definitely effective as an induction agent and has less side effects. Therefore midazolam maleate is regarded as a more effective agent than diazepam as an induction for general anesthesia.