발생중인 병아리의 사이뇌에서 NPY 양성반응세포의 분포

이미영,박일권,이경열,권효정,송치원,박미선,이강이,하권수,김원식,김무강,Lee, Mee-Young,Park, Il-Kwon,Lee, Kyoung-Youl,Kwon, Hyo-Jung,Song, Chi-Won,Park, Mee-Sun,Lee, Kang-Iee,Ha, Kwon-Soo,Kim, Won-Sik,Kim, Moo-Kang 대한수의학회 2002 大韓獸醫學會誌 Vol.42 No.1

This study deals with the distribution and morphological study of the neurons with the neuropeptide Y (NPY) in developing chick brain. The developing brains of Korean native chicks at embryonic days 8 (E8), E10, E12, E14, E16, E18, and E20 were used. The chicks were perfused with 4% paraformaldehyde through the left ventricle and aorta. The brains were removed and transferred into 30% sucrose, and then cut in a cryostat into $60{\mu}m$ in thickness. The sections were immunostained with free-floating and avidin-biotin complex (ABC) methods. The numerous neurons with NPY were first observed in nucleus rotundus of diencephalon at E8. In particular, neurons in nucleus rotundus had the well-developed processes. At E12, the neurons with NPY were distributed widely in diencephalon; nucleus septalis lateralis, medialis, nucleus magnocelluaris preopticus dorsalis, medialis, ventralis, nucleus preopticus medialis, nucleus dorsolateralis anterior thalami pars magnocellularis, and nucleus paraventricularis magnocellularis (paraventricular nucleus) except nucleus rotundus. From E12 to E20, positive neurons were oval-shaped, changed gradually into the spherical- and multipolar-shaped. The shapes of processes were also omnidirectional and the number of those were less than in telencephalon. As the chicks developed, the morphology of neurons with NPY showed the tendency to increase in their sizes and numbers.

특집 - 오픈액세스와 크리에이티브 커먼즈

이미영,Lee, Mi-Yeong 한국도서관협회 2011 圖協會報 Vol.52 No.5

빅데이터 처리 및 저장관리 기술동향 및 전망

이미영,최완,Lee, Mi-Young,Choi, Wan 한국정보통신학회 2012 한국정보통신학회지 Vol.13 No.1

과학기술분야 연구기관의 공통기능 보존기간기준표 설계 사례

이미영,박윤미,심세현,김슬기,김현우,주미경,Lee, Mi-Young,Park, Yun-Mi,Shim, Se-Hyun,Kim, Seul-Gi,Kim, Hyun-Woo,Joo, Mi-Kyoung 한국기록관리학회 2018 한국기록관리학회지 Vol.18 No.3

본 연구는 연구기관 기록관리업무에서 기본적으로 요구되는 기록물 분류체계와 평가도구로서의 보존기간기준표를 공동으로 설계했던 과정에 대한 기록이다. 8개 기관이 자발적으로 참여하여 약 4개월 동안 공통기능 16개, 단위업무 66개, 기록물철 381개로 구성된 보존기간기준표를 설계하였다. 그 과정은 '참여기관 전체의 기록관리 관련 규정 검토, 보존기간기준표의 계층구조와 범위 결정, 16개 공통기능 도출, 기능별 단위업무 도출, 단위업무별 기록물철 구성, 기록물철별 보존기간 책정'의 순으로 진행되었다. 연구기관 및 연구기록 관리에 특정된 국가주도의 연구기록 관리 정책과 전략을 당장은 기대하기 힘든 상황에서 과학기술분야 연구기관 기록관리담당자들이 공동으로 설계한 보존기간기준표는 기관에서 유용한 기록관리도구가 될 수 있을 것이다. 또한 유사기관 기록관리담당자들간의 이러한 협업 노력은 향후 새로운 정책과 혁신플랜에도 공동으로 대응할 수 있는 의미있는 경험이 될 것이다. This study is a record of the process of jointly designing the records classification scheme and the retention schedule for archival appraisal, which are vital in records management. A total of 8 institutes participated voluntarily and redesigned the retention schedule, which consists of 16 common functions, 66 tasks, and 381 files for about 4 months. The process consists of reviewing the regulations related to the records management of the participating organizations, determining the hierarchy and scope of the retention schedule, deriving 16 common functions as well as the unit task for each function, and constructing the file of each task. In situations wherein it is difficult to expect the government-led policy and strategy specific to the research institute and the research records management, the retention schedule designed jointly by the records managers of the scientific and technological field serves as a useful records management tool. This collaborative effort between records managers of similar agency records will also be significant in jointly coping with the new policy and innovation plans in the future.

멀티미디어 통합 정보검색 프레임워크를 지원하는 OODBMS

이미영,채미옥,박순영,이규웅,김완석,김영준,Lee, Mi-Yeong,Chae, Mi-Ok,Park, Sun-Yeong,Lee, Gyu-Ung,Kim, Wan-Seok,Kim, Yeong-Jun 한국정보처리학회 2000 정보처리학회논문지 Vol.7 No.2

As the multimedia application services have been getting various in Internet, need of multimedia database management system which can manage various multimedia information effectively has been increased. The multimedia application generally needs the features to store, manage, retrieve the multimedia data. We need a database management system framework that may be easily integrated with these features. This paper proposes th database management system framework providing the easy integration with various multimedia information retrieval. The framework uses OQL as the retrieval interface, so that user can use it easily. It can be integrated dynamically and easily with various multimedia retrieval method as a loosely coupled system. In addition there is no performance degradation caused in a loosely coupled system.

전화 상담사례에 나타난 부부갈등문제와 대응행동

이미영,박혜인 ( Mi Young Lee,Hye In Park ) 대한가정학회 1995 Human Ecology Research(HER) Vol.33 No.1

한국산 무우로부터 Far Migrating Anionic isoperoxidase A3 의 정제 및 성질

이미영,김승수 ( Mi Young Lee,Soung Soo Kim ) 생화학분자생물학회 1990 BMB Reports Vol.23 No.4

A far migrating anionic isoperoxidase, named A₃, was isolated from Korean radish (Raphanus sativas L.) root. Purification of the enzyme was accomplished by CM-cellulose chromatography, DEAF-Sephacel chromatography and Sephadex G-75 gel filtration. The enzyme was a glycoprotein having molecular weight of approximately 50,000 as determined by SDS-PAGE and Sephadex G-150 gel filtration and the pI value was 3.0. The optimum pH of the enzyme was 6.0 for guaiacol and H₂O₂and the Km values for guaiacol and H₂O₂ were 8 mM and 1 mM, respectively. Substrate studies with natural phenolic compounds were performed and their Km values were determined. In comparison with other Korean radish isoperoxidases, A₃ had higher affinity for esculetin. A particular interest is that the enzyme showed as sigmoidal substrate saturation curve against scopoletin despite of its single Subunit structure.

5배위 결합된 옥사포스포린을 이용한 제미널 비스포스포노 아민 유도체의 합성에 관한 연구

이미영,정강연,Lee, Mi Young,Jung, Kang Yeoun 대한화학회 1999 대한화학회지 Vol.43 No.3

Geminal bisphosphonates have been well known to be effective inhibitors of various calciumrelated disorders such as Paget's disease, hypercalcemia of malignancy, and osteoporosis. To synthesize bisphosphonates, we have used the pentacovalent oxaphospholene prepared from methyl vinyl ketone and triethyl-phosphite. Υ-Ketobisphosphonates are obtained by bromination, applied Westheimer reaction, and hydrolysis of synthesized oxaphospholene. This compound was converted to the N-alkylated Υ-aminobisphosphonates by the reductive amination. Conversion of the resulting secondary amine to the tertiary one, followed by introduction of the second alkyl group on the nitrogen, was led to the synthesis of new N,N'-dialkylated Υ-aminobisphosphonates. 제미널 비스포스폰에이트기를 포함하는 화합물들은 칼슘과 관련된 다양한 질병들 즉 Paget's disease, 악성칼슘과다증, 골다공증등에 약효가 있는 것으로 잘 알려져 있다. 이러한 화합물을 합성하기 위하여 먼저 methylvhyl ketone과 triethylphosphite를 가지고 5배 위된 옥사포스포린 화합물을 합성하였다. 이렇게 합성된 5배위 결합된 옥사포스프린을 bromination, 응용된 Westheimer반응, 그리고 가수분해를 통해서 Y-keto-bisphosphonates를 얻을 수 있었다. 그리고 이 Y-ketobisphosphonates 화합물들은 환원성아민화를 이용해서 N-알킬화된 Y-aminobisphosphonates로 전환하였다. 이렇게 합성된 2차아민 형태의 N-알킬화된 Y-aminobisphosphonates는 N-알킬화반응으로 3차아민을 만든 후 N,N디알킬화된Y-aminobisphosphonates 화합물로 합성할 수 있었다.

천마추출액을 이용한 멥쌀 죽 조청의 항산화 활성 및 품질 특성

이미영,Lee, Mi Young 한국식품조리과학회 2015 한국식품조리과학회지 Vol.31 No.5

This study was performed to investigate the effect of Gastrodia elata extract on the quality characteristics of Non-glutinous rice porridge Jochung, saccharide by barley malt. Non-glutionous Rice Porridge Jochung with 0% (NGR1), 5% (NGR2), 10% (NGR3), 15% (NGR4) and 20% (NGR5) Gastrodia elata extract were produced. Moisture content and Solids content the interaction of two factors, the pH decreased with increasing Gastrodia elata extract concentration. Reducing sugar was significantly higher in groups containing Non-glutinous Rice Porridge Jochung (NGR) with Gastrodia elata extract added than the control group, especially the 15% NGR4 addition group with $1.22{\pm}0.02g/L$. Free acidity contents were 27.27 meq/kg control and 29.67~41.03 meq/kg among the samples with p<0.001. There were significant levels of total phenolics and TEAC found for the antioxidant activity of the Jochung samples with Gastrodia elata extract added. Increasing the ratio of Gastrodia elata Extract in Jochung tended to decrease color value. The results showed that Jochung containng less than 15% Gastrodia elata Extract gave the highest scores in quality characteristics and sensory evaluation.

임상 간호사의 직장 내 괴롭힘, 공감능력, 회복탄력성이 직무만족에 미치는 영향

이미영,박영례,Lee, Mi Young,Park, Youngrye 한국중환자간호학회 2021 중환자간호학회지 Vol.14 No.2

Purpose : The purpose of this study was to understand the relationship between workplace bullying, empathic ability, resilience, and job satisfaction to provide basic data for the development of programs and education aimed at improving nurses' job satisfaction. Methods : Data were collected through a structured questionnaire disseminated to nurses working in general hospitals. A total of 226 questionnaires were used for the analysis. We analyzed the data using descriptive statistics, an independent t-test, a one-way ANOVA, Pearson's correlation coefficient, and a stepwise multiple regression analysis. Results : Nurses' job satisfaction showed a significant positive correlation with empathic ability and resilience and a significant negative correlation with workplace bullying. Additionally, resilience, workplace bullying, empathic ability, religion, and the hope of moving to another department were significant factors affecting job satisfaction. The explanatory power of these variables for job satisfaction was 41.0%. Conclusion : To improve job satisfaction, a strategy to lower workplace bullying and increase empathic ability and resilience is necessary. The results of this study suggest the need for further research to develop educational programs for nurses to strengthen their empathic ability and resilience.