위축성 위염과 장상피화생을 어떻게 호전시킬 수 있을까?

오정환 대한상부위장관ㆍ헬리코박터학회 2018 Korean Journal of Helicobacter Upper Gastrointesti Vol.18 No.4

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단거리 달리기에서 숙련도에 따른 스탠딩 스타트 동작의 운동학적 비교분석

오정환,윤인수,신의수,이채민,서진영 한국사회체육학회 2018 한국사회체육학회지 Vol.0 No.72

The purpose of this study is to compare and analyze the kinematics according to proficiency in standing start operation to improve sprints records. The conclusion is as follows. First, the expert’s time required for standing start operation according to proficiency level, was shorter than that of non-expert. There was a statistically significant difference between P1, P2 and total time spent (p <.05). Second, the expert’s COM(center of mass) horizontal position of the standing start operation according to the proficiency level, was longer than that of the non-expert, and showed a significant difference in E1 and E4 (p <.05). And COM vertical position was higher in the non-expert than in the expert, and was significantly different between E2 and E3 (p <.05). Third, the expert’s COM horizontal speed was faster in all events than the non-experienced (p <.05). And the COM vertical velocity was significantly different between E2 and E4 (p <.05). Fourth, the expert’s standing start operation stride according to the rating, showed a significant difference. It was the longest in all segments compared to that of the non-expert (p <.05). Fifth, the angle of the right hip joint was significantly different between the E3 and E4 (p <.05) and the E3 on the left (p <.05). Sixth, the angles of the right and left knee joints according to the proficiency level during the standing start operation were significantly different in E2, E3 and E4 (p <.05). Seventh, the angle of the right ankle joint according to the proficiency level showed a significant difference in E3 during the standing start operation (p <.05), and the angle of the left ankle joint did not show any significant difference. Eighth, the angle of trunk tilt was small in E1 and E2, and showed a significant difference (p <.05).

Preliminary results of 86 GHz GMVA observations on AGN

오정환 한국천문학회 2013 天文學會報 Vol.38 No.1

미국의 초・중등 체육 교과과정 개혁 방향에 관한 담론

오정환,백준형 한국홀리스틱융합교육학회 2022 홀리스틱융합교육연구 Vol.26 No.3

본 연구는 미국의 학교체육 교육과정의 실행양상과 그 시행과정에서 발생한 문제점을 고찰하고, 체육이 학교문화 사이에서 적절한 교과목으로서 자리매김하기 위한 올바른 개혁 방향을 논의하는 데 그 목적이 있다. 1990년대 이후, 미국의 학교체육 분야는 지역화된 교육과정 접근방식의 오랜 전통을 기반으로 하여 ‘표준’의 개념을 도입하였다. 폭넓은 의미로 정의된 체육교과 학습표준의 특성은 지역 및 교사 자율성을 허용하였던 반면, 이는 또한 주와 지역들을 가로질러 매우 이질적인 형태의 표준기반교육 프로그램의 형성을 초래하였다. 체육이 독립적인 학교 교과로서의 신뢰를 유지하기 위해 보다 일관성 있고 체계적인 변화가 필요한 시점이다. 하지만 사회경제적으로, 문화적으로, 그리고 지역적으로 다양한 미국 고유의 학습환경에서 국가 수준의 획일적인 교과과정의 도입은 그리 적절한 개혁 방향으로 보이지 않는다. 인종/민족 집단 및 사회경제적 계층 간 분열, 국가 개혁에 대한 지역 주체들의 반감 및 저항, 그리고 합법적 지식의 권력 재생산 등의 다양한 이념적 문제를 일으킬 소지가 있다. 획일적인 개혁안을 통해 체육교과 교육과정의 완전한 변모를 꾀하기보다는, 현행 표준중심교육의 개정을 통해 학교체육 프로그램을 개선해 나아가야 할 것으로 사료된다.

Deiodonitration reactions of Iodine-rich compounds

오정환,이병일,김남태,신혜정,김진석,김영규 한국공업화학회 2016 한국공업화학회 연구논문 초록집 Vol.2016 No.0

Iodine-rich compounds like bis(3,4,5-triiodo-1H-pyrazol-1-yl)methane and bis(3,4,5-triiodo-1H-pyrazol-1-yl)ethane synthesized by our group can be used for Agent Defeat Weapons. Deiodonitration reactions of polyiodo compounds would be an efficient way to produce useful polynitro compounds as potential high energy materials. Our group`s iodine-rich compounds could be promising high energy materials via the deiodonitration reaction, because they have low sensitivity due to the stable pyrazole ring and their symmetric structure. In this study, both 3,4-dinitro-5-iodo-1-methylpyrazole and 3,4-dinitro-5-iodopyrazole have been obtained effectively via the deiodonitration with nitric acid. Bis(3,4-dinitro-5-iodo-1H-pyrazol-1-yl)ethane has been also synthesized from bis(3,4,5-triiodo-1H-pyrazol-1-yl)ethane via the deiodonitration. Compared to the stepwise nitration method, the deiodonitration is more efficient method for polynitro compounds that is applicable as high energy materials.

구강악안면외과 영역의 전암병소 및 악성종양 치료를 위한 광역학 요법의 이용

오정환,Alexander Kuebler,Joachim E. Zoeller 대한구강악안면외과학회 2002 대한구강악안면외과학회지 Vol.28 No.3

Photodynamic therapy (PDT) is based on a photochemical reaction which is initiated by light activation of a photosensitizer. The photosensitizer accumulates more in tumor tissues than in normal tissues and is activated with specific wavelength of light, usually laser. The photochemical reaction produces highly reactive oxygen products causing cytotoxiciy and vascular shutdown to the tumor. The advantages of PDT are its relative selective tumor destruction and tissue healing by regeneration, which can maintain important structures with very good functional and esthetic results. Therefore, PDT is considered as an alternative modality for cancers of the head and neck. In this article, we will report three cases of photodynamic therapy for treatment of oral leukoplakia, squamous cell carcinoma, and basal cell carcinoma of head and neck. It was observed that premalignant and malignant lesions responded well to the photodynamic therapy with Aminolevulinic acid (ALA) and Foscan. Photodynamic therapy can be considered as a new treatment method for the premalignant and malignant tumors in Oral and Maxillofacial Surgery.

청소년기에 진단된 선천성 근육긴장성 이영양증

오정환,이재영,이정석,최재철,강지훈,강사윤 대한신경과학회 2008 대한신경과학회지 Vol.26 No.4

Type 1 myotonic dystrophy (DM1) is an autosomal-dominant inherited disorder with multisystem involvement, caused by an abnormal expansion of CTG sequence of the dystrophia myotonica protein kinase (DMPK) gene on chromosome 19. Congenital myotonic dystrophy (CDM) is the most severe phenotypic form of DM1. CMD tends to be observed in congenitally affected fetus or neonates born to affected mothers. We report a patient confirmed as CDM during the adolescent period.

Helicobacter pylori 이차 사제 병합요법의 제균율

오정환,김태호,정대영,박재명,김재광,최상욱,한석원,정인식 대한소화기내시경학회 2009 Clinical Endoscopy Vol.39 No.3

Background/Aims: There has been a substantial decline in Helicobacter pylori (H. pylori) cure rates with standard triple therapy in recent years. Therefore, great emphasis has been placed on second line treatment for its successful eradication. The aim of this study was to evaluate the efficacy of bismuth based quadruple therapy as a second line treatment for H. pylori infection. Methods: From January 2001 to December 2007, the hospital records of 215 patients who failed to the standard triple therapy were reviewed retrospectively. The patients were treated with bismuth based quadruple therapy (PPI, bismuth 120 mg qid, metronidazole 500 mg tid, and tetracycline 500 mg qid). The successful eradication of H. pylori was defined as negative result from histology, CLO test or 13C-urea breath test. Results: Eradication rates by intention-to-treat (ITT) and per-protocol (PP) analyses with quadruple therapy were 64% (137/215) and, 91% (137/151) respectively. The eradication rates were not significantly different according to diseases, duration of treatment, area and proton pump inhibitors. The PP eradication rates for the years from 2001 to 2007 were not significantly different. Conclusions: The bismuth based quadruple therapy is still effective as the second line treatment for the eradication of H. pylori. 목적: 최근 일차 헬리코박터 제균율이 감소하는 추세로 이차 치료의 대상자는 더욱 늘어나고 있어, 2차 치료의 필요성이 커지고 있다. 저자들은 일차 제균 치료에 실패한 환자에서 사제 요법을 이용한 이차치료의 제균율을 조사하여 제균 효과를 알아보았다. 대상 및 방법: 2001년 1월부터 2007년 12월까지 서울과 경기도를 방문하여 일차 제균 치료에 실패한 환자 중 2차 제균 치료를 시행 받은 환자 215명을 대상으로 의무기록을 통하여 후향적으로 분석하였다. H.pylori 2차 제균 치료로 bismuth 포함 사제요법을 7일에서 14일까지 투여하고, 사제요법 종료 4주 후에 요소호기검사와 조직검사를 시행하여 제균 판정을 하였다. 결과: 이차 제균 치료의 제균 성공율은 ITT (intention to treat) 분석에서 64% (137/215), PP (per protocol) 분석에서 91% (137/ 151)이었다. 질환의 종류와 제균 기간, 지역, 프로톤 펌프 억제제의 종류에 따른 제균 성적의 차이는 통계적으로 유의하지 않았다. 2001년부터 2007년까지 시간에 따른 제균 성공율의 차이는 없었다. 결론: 우리나라에서 bismuth포함 사제 요법의 성공율은 90%이상으로 헬리코박터의 이차 제균 치료로 유용하다.

觀光現像의 發展過程에 관한 考察 - 호텔의 생성과정을 중심으로

오정환 경기대학교학술진흥원 1988 京畿行政論集 Vol.3 No.-

Periodic Limb Movements During Sleep Associated with Human T-Lymphotropic Virus Type I-Associated Myelopathy

오정환,김준순,강사윤,성정준 대한수면연구학회 2016 Journal of sleep medicine Vol.13 No.2

Periodic limb movements during sleep (PLMS) are frequently observed in the general population, although such movements may be associated with a variety of medical and neurological disorders. Human T-lymphotropic virus type I-associated myelopathy (HAM) is a rare progressive disease in which abnormalities are rarely observed on spinal images. We present the case of a 55-year-old woman with PLMS who was later diagnosed with HAM. The current case indicates that HAM can be considered a possible cause of PLMS