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남경식,차명진,김민주,오미선,민양기,조수진,권기한 대한신경과학회 2007 대한신경과학회지 Vol.25 No.2
Background: Electrical injury can cause serious damage to any part of the nervous system. However spinal cord injury by electricity itself rarely develops. If develops, it can be either electrical myelopathy (immediate or delayed), spinal atrophic paralysis and/or amyotrophic lateral sclerosis-like disease. We are going to report the clinical, electrophysiological and radiographic features of electrical myelopathy (immediate or delayed) of 18 patients. Methods: We retrospectively reviewed the clinical, electrophysiological and radiographic data of patients who were diagnosed as electrical myelopathy. Results: Among 1,306 patients with electrical injury, 18 patients (1.4%) had electrical myelopathy. Fifteen patients (83%) had motor symptoms and 16 patients (89%) had sensory symptoms or signs. It is interesting for seven patients to appear their neurological symptoms or signs with a day after electrical injury. Somatosensory evoked potentials (SEP) which were done in 17 patients showed abnormal central conduction defects in 12 patients (70.5%). Magnetic resonance images (MRI) of spinal cord, however, did not show any abnormalities in all the tested patients (15 patients). Conclusions: Clinically, electrical myelopathy can cause not only motor but also sensory symptoms or signs. Interestingly, there were several immediate as well as delayed forms of electrical myelopathy In most patients with electrical myelopathy, SEP was a useful method to detect objective abnormalities but MRI was not.
남경식,정경원,박무인,박선자,문원,김성은,김재현 대한상부위장관ㆍ헬리코박터학회 2017 Korean Journal of Helicobacter Upper Gastrointesti Vol.17 No.1
Solitary renal metastasis of esophageal cancer is rarely encountered. Herein, we report the case of a 47-year-old man who developed a solitary renal metastasis after concurrent chemoradiotherapy followed by esophagectomy with esophagogastrostomy for esophageal squamous cell carcinoma, and treatment with nephrectomy and subsequent chemotherapy. Histopathological evaluation after operation revealed that the kidney mass was a metastatic lesion from esophageal cancer. He completed 15 cycles of palliative chemotherapy after nephrectomy and remained cancer-free for 36 months. Although lymph node metastasis occurred during regular follow-up, no evidence of lymph node metastasis was found on the imaging study after 9 cycles of chemotherapy with radiotherapy. (Korean J Helicobacter Up Gastrointest Res 2017;17:-44)
남경식,박희웅,박민기,박수호,황지연,김동규,김성준 영남대학교 의과대학 2017 Yeungnam University Journal of Medicine Vol.34 No.1
Cytomegalovirus (CMV) colitis, which is rare in an immunocompetent patient, was encountered in a 67-yearold man who was admitted due to persistent diarrhea. The first diagnostic tool was colonoscopy, which showed multiple ulcers from cecum to rectum. The secondary tool was CMV polymerase chain reaction, and CMV colitis was diagnosed. Intravenous ganciclovir therapy was administered, which resulted in improvement of diarrhea and ulcers throughout the colon were healed. Asymptomatic colon perforation was detected during diagnostic testing, which improved over the conventional treatment. CMV colitis is rare in immunocompetent patients, but it is essential for the differential diagnosis.
남경식 대한뇌졸중학회 2003 Journal of stroke Vol.5 No.1
Department of Neurology, College of Medicine Hallym UniversityWe report a case of isolated total finger paralysis due to small cortical infarction. An 83-year-old diabetic man was admitted with a chief complaint of sudden left finger weakness. On neurological examination, he could not make any motion in all five digits of his left hand. MRI of the brain showed small cortical infarction on the right precentral gyrus. The vertical extent of the lesion, which was present through five serial axial scans around hand knob area, may explain the complete paralysis of all five fingers in this patient.
갈락토세레브로시다아제 유전자 분석으로 확진된 크라베(Krabbe)병 1예
남경식,류상효,성영희,오미선,정헤원,이병철,이기형,민기식,한성희,기창석,김종원 대한신경과학회 2004 대한신경과학회지 Vol.22 No.2
Krabbe disease is an autosomal recessive disorder involving white matter caused by deficient activity of the lysosomal galactocerebrosidase (GALC). A typical infantile-onset patient shows developmental regression, spasticity, and seizure before 6 months of age, and dies within 2 years. Previously, one case was confirmed by an enzyme test in Korea. We herein report a 2 year-old girl who showed the characteristic clinical course and neuroimaging features of infantile-onset Krabbe disease. Genetic testing identified the compound heterozygote mutations in the GALC gene; NLWE212_ 215TP/302A.
Myxoinflammatory Fibroblastic Sarcoma in the Chest Wall
남경식,박인규,배미경,김기정 대한흉부외과학회 2012 Journal of Chest Surgery (J Chest Surg) Vol.45 No.1
Myxoinflammatory fibroblastic sarcoma (MIFS) is a recently defined rare tumor. It is mainly found in the upper and lower extremities of adults. Due to its high local recurrence rate and low metastatic rate, it is classified as a low grade-malignancy. Accurate diagnosis and early, wide excision are important for prognosis. Herein, we report a case of MIFS in a 35-year-old male patient that presented in an unusual location, the left chest wall. To our knowledge, this is the first reported case of MIFS in Korea and the second case to be reported within the global scientific literature involving the chest wall.
Clopidogrel 투여 후 발생한 가역적 무미증 1례
남경식 대한뇌졸중학회 2002 Journal of stroke Vol.4 No.1
We report a case of reversible ageusia as an adverse effect of an antiplatelet agent, clopidogrel. A 68-year-old man visited us because of recently developed anorexia and the loss of taste sensation. Two years before, he had had sudden diplopia and took ticlopidine under the diagnosis of lacunar infarction. It was changed to clopidogrel because of frequent nasal bleeding 4 months before. On neurological examination he could feel touch sense normally but could not feel any kinds of taste sense at all on both sides of his tongue. Brain MRI showed no definite abnormality. Eight weeks after discontinuation of clopidogrel his symptoms disappeared. So far, only 2 cases of ageusia induced by clopidogrel have been reported worldwide, to our knowledge. Clinicians should be alert to the possibility that ageusia can be produced as an adverse effect of clopidogrel treatment. Korean Journal of Stroke 2002;4(1): 58~60