유레아 및 티오유레아 유도체의 합성과 활성화된 대식세포의 NO 생성 저해효과

김윤정,천예진,임효진,류재하,전라옥,Kim, Yoon-Jung,Cheon, Ye-Jin,Lim, Hyo-Jin,Ryu, Jae-Ha,Jeon, Ra-Ok 대한약학회 2007 약학회지 Vol.51 No.4

Several ureas and thioureas were designed and synthesized and their inhibitory activities of NO production in lipopolysaccharide-activated macrophages were evaluated. Among these compounds, indole-containing thiourea 6e was the most potent showing 17.4 ${\mu}M$ of $IC_{50}$ value.

대구 지역 청소년 및 미혼 여성 자궁내막증 환자의 임상 특성에 관한 비교연구

김윤정,최민혜,정민지,이정호,이택후,Kim, Yoon-Jeong,Choi, Min-Hye,Chung, Min-Ji,Lee, Jung-Ho,Lee, Taek-Hoo 대한생식의학회 2007 Clinical and Experimental Reproductive Medicine Vol.34 No.3

목 적: 본 연구는 청소년기와 성인 미혼 여성에서의 자궁내막증의 특징을 비교해 보고 청소년기에 조기 발견 및 치료의 중요성에 대해 알아보고자 한다. 연구방법: 000년 1월부터 2007년 9월까지 대구 소재 두 대학병원을 방문하여 수술을 시행한 환자를 대상으로 청소년 (14$\sim$21세, 23예)과 성인 미혼 여성 (22$\sim$26, 107예)의 자궁내막증의 임상양상, 진단과정, 수술소견, 혈액검사소견(CA-125) 등을 의무 기록 분석을 통한 후향적인 방법으로 비교하였다. 결 과: 대구 지역 청소년은 cyclic pain을 주증상으로 흔히 호소하였다. 청소년은 52.2%가 stage I, II였으며, stage III는 47.8%, stage 4는 없었다. 반면에 성인에서는 stage I이 1.86%에 불과하였으며, stage II 및 stage III가 82.2%로 대다수를 차지하였으며 stage IV도 15.8%차지하였다. 청소년에서도 CA-125가 상승되어 있는 경우가 많았고 이를 병의 경과 관찰에 이용할 수 있을 것이다. 청소년에서 순수 자궁내막증을 의심하여 수술한 경우는 전체 23예 중에 10예에 불과하였으며 이외 13예는 다른 진단으로 시행한 수술에서 우연히 발견되었다. 이는 전체 56.5%로 많은 비중을 차지하며, 성인 여성에서 27.5%에 불과한 것과는 대조적이다. 결 론: 대구 지역 청소년들을 대상으로 시행한 이번 연구에서는 청소년기에서 주기성 통증이 우세하였으며 이는 임상증상 만으로도 조기 발견에 도움이 될 수 있을 것이다. 자궁내막증은 진행하는 병임은 틀림없으므로 만성 골반통이 있는 청소년을 대상으로 적절한 산부인과적 검사를 통한 조기 진단 및 치료가 중요할 것으로 사료된다. Objective: The purpose of this study is to find out the differences of clinical characteristics of endometriosis and to emphasize the significance of early diagnosis of endometriosis to protect disease progression in adolescents. Methods: A retrospective analysis was carried out. All cases (n=130) were diagnosed surgically as endometriosis between January 2000 and August 2007 in two university hospitals in Daegu. Adolescents were 23 cases and unmarried young women were 107 cases. Data were collected through review of medical records. Results: The predominant symptom in adolescents was cyclic pain. 52.2% of adolescent patients were stage I or II. And stage III was 47.8% but stage IV was none. The other side 82.2% of unmarried young women patients were stage II or III and stage IV was 15.8%. Serum CA-125 level was elevated in adolescents, also. But there was no significant difference between the two groups. Conclusions: Endometriosis is progressive disease. Early diagnosis is necessary for prevention of the disease progression and free from pain. Appropriate gynecologic examination and careful concerns about adolescents are mandatory.

2-beam Coupling 방법을 이용한 광 고분자 형광 패턴 형성

김윤정,김정훈,심보연,이명규,김은경,Kim, Yoon-Jung,Kim, Jeong-Hun,Sim, Bo-Yeon,Lee, Myeong-Kyu,Kim, Eun-Kyoung 한국광학회 2010 한국광학회지 Vol.21 No.1

아크릴레이트계 모노머를 사용한 최적화 된 포토폴리머에 안트라센 형광폴리머를 첨가하여 형광 특성을 가지는 포토폴리머를 제조하고, 514 nm 레이저를 이용하여 2-beam coupling 방법으로 형광 포토폴리머 필름 위에 회절격자를 형성하였다. 기록 시작 후 30초 이내에 선명한 fluorescent line pattern 이 형성되었으며, 회절격자 형성 뒤, 패턴이 형성된 부분에서 형광 세기의 증가가 관찰되었다. 기록 시 간섭 빔 앞에 mask pattern 을 이용하여 $50\;{\mu}m$ gap electrode 패턴을 형성하였다. 이 때 형성된 패턴은 micron scale gap패턴 안에 회절격자로부터 생성된 submicron scale의 grating line을 보였다. 이는 beam의 광 고분자 film 표면에 대한 각도($3.6^{\circ}$, $15^{\circ}$), 패턴에 사용된 광 고분자의 굴절률 등으로부터 Bragg's equation 을 사용하여 계산된 이론적인 grating 간격 ($0.6\;{\mu}m$) 과 오차범위 안에서 일치 하였다. Fluorescent photopolymer film was prepared with composition containing acrylate monomer, binder, a visible light sensitive photo initiator, and fluorescent anthracene polymer. A fluorescent grating pattern was inscribed on the photopolymer film using a 2-beam coupling method. A 514 nm laser was coupled to generate a beam-interference pattern. A highly fluorescent diffractive line pattern was formed on the fluorescent photopolymer within 30 sec. of exposure. The fluorescence intensity was highly enhanced in the patterned area, possibly due to the change in the environment of the fluorescent polymers by the photo-polymerization of monomers. Under a photo-mask, a gap electrode pattern was formed of fluorescent gratings with a sub-micron scale, which was matched well to the calculated value ($2.5\;{\mu}m$ and $0.6\;{\mu}m$) based on the refractive index of the photopolymer and beam incident angle ($3.4^{\circ}$, $15^{\circ}$) to the photopolymer surface.

Modeling the Present Probability of Urban Woody Plants in the face of Climate Change

김윤정,이동근,박찬,Kim, Yoon-Jung,Lee, Dong-Kun,Park, Chan The Korea Society of Environmental Restoration Tec 2013 한국환경복원기술학회지 Vol.20 No.3

The effect of climate change on urban woody plants remains difficult to predict in urban areas. Depending on its tolerances, a plant species may stay and survive or stay with slowly declining remnant populations under a changing climate. To predict those vulnerabilities on urban woody plants, this study suggests a basic bioclimatic envelop model of heat requirements, cold tolerance, chilling requirements and moisture requirements that are well documented as the 'climatic niche'. Each component of the 'climatic niche' is measured by the warmth index, the absolute minimum temperature, the number of chilling weeks and the water balance. Regarding the utility of the developed model, the selected urban plant's present probabilities are suggested in the future climate of Seoul. Both Korea and Japan's thermal thresholds are considered for a plant's optimal climatic niche. By considering the thermal thresholds of these two regions for the same species, the different responses observed will reflect the plant's 'hardening' process in a rising climate. The model illustrated that the subpolar plants Taxus cuspidata and Ulmus davidiana var. japonica are predicted to have low suitability in Seoul. The temperate plants Zelkova serrata and Pinus densiflora, which have a broad climatic niche, exhibited the highest present probability in the future. The subtropical plants Camellia japonica and Castanopsis cuspidata var. sieboldii may exhibit a modest growth pattern in the late 21C's future climatic period when an appropriate frost management scheme is offered. The model can be used to hypothesize how urban ecosystems could change over time. Moreover, the developed model can be used to establish selection guidelines for urban plants with high levels of climatic adaptability.

유방의 점액성 암종의 진단시 세침흡인 검사의 의의

김윤정,공경엽,허주령,박정미,안세현,김온자,Kim, Yoon-Jung,Gong, Gyung-Yub,Huh, Joo-Ryung,Park, Jeong-Mi,Ahn, Sei-Hyun,Kim, On-Ja 대한세포병리학회 1996 대한세포병리학회지 Vol.7 No.2

Fine needle aspiration(FNA) is an effective tool in diagnosing mammary carcinoma. We experienced 7 cases of histologically confirmed mammary mucinous carcinoma among 3,052 aspirated cases of breast from 1992 to 1996 in Asan Medical Center. The average age of the patient was 48(33-64) years. The mean size of the lesions was $1.6(0.7{\sim}3)cm$, and they were palpated as well-defined, firm to hard masses. The cytologic features that may be useful in making a FNA diagnosis of mucinous carcinoma of the breast were analysed. Mucinous background and tumor cell clusters with occasional single cells were observed in all cases. Among them, two cases showed abundant scattered single cells, whereas only few single cells were seen in the other two cases. Tumor cells exhibited mild pleomorphism in four cases and moderate pleomorphism in three cases. Nucleoli tended to be not prominent and are observed in three cases, rarely noted in other three cases and not seen in one. There was microcalcification in four cases(57%). In conclusion, mucinous background and clustered tumor cells showing mild to moderate pleomorphism with characteristic clinical findings allow us to diagnose mucinous carcinoma of the breast.

소방안전 빅데이터 플랫폼을 활용한 소방 빅데이터 분석에 관한 연구

김윤정(Kim Yoon Jung),김연진(Kim Yeon Jin),김무빈(Kim Moo Bin),박봉섭,김경배(Kim Gyoung Bae) 한국통신학회 2021 한국통신학회 학술대회논문집 Vol.2021 No.6

최근 대형화되는 재난 사고와 다양한 요인에 의해 복합적으로 발생하는 화재 상황에 효과적으로 대응하기 위해서는 발생 요인들에 대한 데이터의 수집과 분석이 필요하다. 소방청은 이러한 문제를 해결하기 위하여 소방안전 빅데이터의 수집과 분석에 지속적인 노력을 기울이고 있으며, 현재 소방안전 빅데이터 플랫폼 및 센터 구축 사업을 진행하고 있다. 소방 안전 빅데이터 플랫폼은 국민의 긴급 재난상황 파악과 대응정보 제공으로 국민 안전을 확보하고, 소방기술 및 용품 연구 개발 정보 제공으로 소방산업 혁신을 지원하며 과학적 선제적 소방재난 예방 및 대응에 필요한 데이터를 제공한다. 본 논문에서는 3단계로 추진하고, 소방청, 한국소방안전원,(주)조인트리, 서원대학교가 참여하고 있는 소방안전 빅데이터 플랫폼의 소개와 플랫폼에서 제공하고 있는 소방 빅데이터 분석에 대한 활용방안을 제시하여 소방안전 플랫폼에 대한 활용도 및 기여도를 높이고자 한다.

대학의 수준별 영어 수업에 대한 연구

김윤정(Kim, Yoon-Jung) 팬코리아영어교육학회(구 영남영어교육학회) 2015 영어교육연구 Vol.27 No.3

This paper presents how Korean EFL college students perceive differentiated English classes offered in college, and how their perceptions differ according to their level of English proficiency. It also examined the students’ improvement in the differentiated classes, and their relationship among their perceptions and improvement. In addition, the study seeks to identify the most significant factor affecting the satisfaction and the perceived effectiveness of such classes. The participants were 141 students from three different levels of classes, i.e., with 50 from advanced classes, 48 from intermediate classes, and 43 from elementary classes. The participants answered questionnaires. The scores of placement and achievement tests were analyzed to examine the student’s improvement in differentiated classes. The results revealed that the participants had positive attitudes toward differentiated classes, in general, in the order of elementary level of students followed by advanced level and intermediate level of students. However, regardless of their perceptions and their level of English, all the participants showed gain in TOEIC scores, with the highest gain found in elementary classes. The appropriateness of the difficulty level in differentiated classes was found to be the most significant factor affecting both the satisfaction and the perceived effectiveness of such classes. Implications and limitations are discussed.

CFD를 이용한 자바라 튜브의 맥동소음저감 최적화 설계에 대한 연구

김윤정(Yoon Jung Kim),정진경(Jin Kyeong Chung),김병준(Byeong Jun Kim),정우원(Woo Won Jeong) 대한기계학회 2014 대한기계학회 춘추학술대회 Vol.2014 No.5-2

소비자의 점포인식과 불평행동 결정요인이 불평행동의도에 미치는 영향: 대형마트와 전통시장을 중심으로

김윤정 ( Yoon Jung Kim ),이승신 ( Seung Sin Lee ) 대한가정학회 2016 Human Ecology Research(HER) Vol.54 No.2

Product complaints allow business operators to learn from and solve problems they have been unaware of and prevent customers from leaving in advance. The ability to deal properly with complaints may improve consumer loyalty and repurchase intentions. This study analyzes consumers` intention in complaining behavior towards supermarkets and traditional markets. This study provides implications for business operators in the establishment of marketing strategies to deal with complaints and perform education related to consumer complaints by the verification of variables that influence intention on complaining behavior. A survey was conducted on housewife consumers who had experience using supermarkets and traditional markets. The major results are as follows: first, in store awareness higher in supermarkets than in traditional markets. Second, determinants of consumer complaint behavior, indicated a belief there was a need to spend more money at traditional markets than supermarkets, where the possibility of complaint success and complaint attitudes were found to be low. Third, intention of complaining behavior was lower at traditional markets than supermarkets. Intentions on private complaining behavior and public complaining behavior were both low. Fourth, intention of private behavior is higher than intention of public behavior for both supermarkets and traditional markets. Fifth, complaint attitudes were variables with the greatest influence on intention of complaining behavior for both supermarkets and traditional markets.

통신위원회의 최근 주요심결례 분석

김윤정(Kim Yoon-Jung) 서울대학교 공익산업법센터 2008 경제규제와 법 Vol.1 No.1