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      • KCI등재

        2003년 국내 원종계 및 종계의 추백리-가금티푸스 감염실태

        김애란,김재홍,이영주,조영미,권준헌,권용국,이윤정,최준구,조성준,김민철,이은경,김창섭,양흥구,곽상익,성환우,모인필,Kim, Ae Ran,Kim, Jae Hong,Lee, Young Ju,Cho, Young Mi,Kwon, Jun Hun,Kwon, Yong Kuk,Lee, Youn Jeong,Choi, Jun Gu,Joh, Sung Jun,Kim, Min C 대한수의학회 2006 大韓獸醫學會誌 Vol.46 No.4

        Serum samples of 30 chickens per flock from 6 grand parent stock (GPS) farms and 70 parent stock (PS) farms were collected for seroprevalent study of pullorum disease-fowl typhoid (PD-FT) infection by serum plate agglutination test (SPA). The incidence of PD-FT infection in GPS flocks and PS flocks were 0% and 15.7%, respectively. Especially PS flocks infected with PD-FT showed age dependent patterns that 22.2% of flocks between 20 to 30 weeks of age and 38.9% of flocks between 30 to 40 weeks of age were positive. The incidence of GPS flocks and PS flocks using Salmonella (S.) gallinarum 9R (SG9R) live vaccine were 33.3% and 58.6%, respectively. The sero-positive rate of 11 flocks were 6.7-83.3% by SPA and 2.9-55.6% by enzyme linked immunosorbent assay (ELISA), and ELISA showed more lower antibody levels than SPA. Furthermore, specific antibodies produced by SG9R vaccination were detectable by SPA using SG9R antigen without cross-reaction with the PD-FT infection.

      • KCI등재

        이중으로 집중된 동적 미세 다엽콜리메이터의 선량학적 특성 평가

        김애란,서재혁,신헌주,박형욱,이기웅,이재춘,김신욱,김지나,박혜리,이희관,강영남,Kim, Ae Ran,Seo, Jae-Hyuk,Shin, Hun-Joo,Park, Hyeong Wook,Lee, Ki Woong,Lee, Jae Choon,Kim, Shin-Wook,Kim, Ji Na,Park, Hyeli,Lee, Heui-Kwan,Kang, Young-Nam Korean Society of Medical Physics 2015 의학물리 Vol.26 No.4

        이중으로 집중된 미세 다엽콜리메이터(Double-focused micro Multileaf Collimator: ${\mu}MLC$)는 보통의 다엽콜리메이터(Multileaf Collimator: MLC)에 비하여 조사면 가장자리 부분의 선량을 급격하게 줄여준다. 이러한 특성 때문에, 미세 다엽 콜리메이터는 정위적 방사선 수술과 치료(Stereotactic Radio-Surgery/RadioTtherapy, SRS/SRT)에 사용되어 왔다. 우리는 Elekta Synergy 선형가속기에 이중으로 집중된 동적 미세 다엽콜리메이터(Double-focused Dynamic micro-Multileaf Collimator: DMLC)를 부착하여 선량학적 특성을 평가하였다. 본 연구에서는, 필름(GafChromic EBT2 film), EDGE 다이오드 검출기, 3차원 물 팬텀을 이용하였다. 깊이선량백분율(Percent Depth Dose, PDD), 엽 투과도(leaf leakage), 반그림자(Penumbra)를 측정하였고, 모든 데이터들은 6MV 광자선으로 측정하였다. 그 결과, DMLC가 1% 이내의 투과도를 갖는것을 확인할 수 있었다. DMLC는 이중으로 집중 되는 구조를 가졌기 때문에 반 그림자가 조사야 크기에 대하여 독립적인 것을 확인하였다. 본 연구에서는 DMLC의 선량학적 특성을 바탕으로, Elekta Synergy에 부착된 DMLC의 적용 가능성을 증명하였다. Double-focused micro-Multileaf Collimator (${\mu}MLC$) is able to create radiation fields having sharper dose gradients at the field edges than common MLC. Therefore, ${\mu}MLC$ has been used for the stereotactic radiosurgery (SRS) and Stereotactic Radiotherapy (SRT). We evaluated the dosimetric characteristics of a doublefocused Dynamic-${\mu}MLC$ (DMLC) attached to the Elekta Synergy linear accelerator. For this study, the dosimetric parameters including, Percent Depth Dose (PDD), Leaf leakage and penumbra, have been measured by using of the radiochromic films (GafChromic EBT2), EDGE diode detector and three-dimensional water phantom. All datas were measured on 6 MV x-ray. As a result, The DMLC shows transmission below to 1% and because of double-focused construction of the DMLC, the penumbras of fields with DMLC are independent from the field sizes. In this paper, the resulting dosimetric evaluations proved the applicability of the DMLC attached to the Elekta Synergy linear accelerator.

      • 신생아 및 영아기의 허쉬슈프렁병 진단

        김대연,김성철,김경모,김애란,김기수,김정선,구현우,윤종현,김진천,피수영,김인구,Kim, Dae-Yeon,Kim, Seong-Chul,Kim, Kyung-Mo,Kim, Ellen Ai-Rhan,Kim, Ki-Soo,Kim, Jung-Sun,Goo, Hyun-Woo,Yoon, Chong-Hyun,Kim, Jin-Cheon,Pil, Soo-Young,Kim, I 대한소아외과학회 2002 소아외과 Vol.8 No.1

        Diagnosing Hirschsprung's disease is a clinical challenge. Hirschsprung's disease should be considered in any child who has a history of constipation dating back to the newborn period. We examined diagnostic methods and their results retrospectively in 37 neonates and infants who underwent both barium enema and anorectal manometry for the diagnosis of Hirschsprungs disease at Asan Medical Center between January 1999 and April 2001. Two radiologists and a surgeon repeatedly reviewed both of the diagnostic results. In anorectal manometry, thirty-four studies were in agreement with the definitive diagnosis, giving an overall diagnostic accuracy of 91.9 % (neonate; 100 %, infant; 85.7 %). The accuracy and specificity of barium enema was lower than those of anorectal manometry, but sensitivity was higher. There was no significant difference between the two methods. Both studies showed findings consistent with the final diagnosis. However, discordant results needed further evaluation or close observation to diagnose accurately. We conclude that Hirschsprungs disease should not be diagnosed by only one diagnostic method.

      • KCI등재

        국내 유통 어린이 및 무기 자외선차단제에서 자외선 차단성분, 보존제 및 중금속 실태 조사

        김애란 ( Aeran Kim ),이유진 ( You-jin Lee ),조윤식 ( Yun-sik Cho ),김현주 ( Hyun-jue Kim ),조상훈 ( Sang-hun Cho ),김양희 ( Yang-hee Kim ),노정원 ( Jeong-won Ro ),박용배 ( Yong-bae Park ) 대한화장품학회 2021 대한화장품학회지 Vol.47 No.4

        본 연구에서는 국내 유통 중인 민감성 피부 대상 자외선 차단제의 안전성 조사를 위해 무기 자외선 차단제 27 건 및 어린이용 자외선 차단제 23 건을 수거하여 자외선 차단 성분 17 종, 보존제 13 종 및 중금속 5 종의 사용 및 혼입 실태을 조사하였다. 그 결과 자외선 차단 성분은 티타늄디옥사이드(41 건), 징크옥사이드(29 건), 비스-에칠헥실옥시페놀메톡시페닐트리아진(10 건) 에칠헥실살리실레이트(8 건) 및 에칠헥실메톡시신나메이트(8 건)순으로 검출되었으며, 보존제는 페녹시에탄올(6 건), 안식향산(1 건), 디히드로초산(1 건) 순으로 검출되었다. 확인된 자외선 차단성분은 모두 표시 사항에 적합 하였으나, 1 개 제품에서 표시사항 외 보존제 성분인 페녹시에탄올이 0.1% 농도로 검출되었다. 중금속 납, 카드뮴, 비소, 안티몬, 니켈은 불검출에서 3.6 μg/g로 다양한 농도로 검출되었다. 이번 연구에서 확인된 자외선 차단성분, 보존제 및 중금속은 화장품 안전기준 등에 관한 규정의 성분별 최대 배합한도 및 최대 허용량 기준에 적합하였다. In this study, 27 inorganic sunscreens and 23 sunscreens for children were collected to investigate the use and incorporation of 17 types of sunscreen agents, 13 types of preservatives, and 5 types of heavy metals. As a result, sunscreen agents were detected in the order of titanium dioxide (41 cases), zinc oxide (29 cases), bis-ethylhexyloxyphenyltriazine (10 cases), ethylhexyl salicylate (8 cases), and ethylhexylmethoxynamate (8 cases), and preservatives were detected in order of phenoxyethanol (6 cases), benzoic acid (1 case), and dihydroacetic acid(1 case). All of the identified sunscreen agents were suitable for labeling, but phenoxyethanol, a preservative component other than labeling, was detected at a concentration of 0.1%. Heavy metals such as lead, cadmium, arsenic, antimony, and nickel were not detected or were detected at various concentrations of less than 3.6 μg/g. All the detected UV filters, preservatives, and heavy metals were less than the allowed maximum amount stipulated by the Regulations on Cosmetic Safety Standards in Korea.

      • KCI등재

        임상 한의사의 이침 사용 실태 조사 보고

        김애란 ( Ae Ran Kim ),이상훈 ( Sang Hun Lee ),김정은 ( Jung Eun Kim ),김보영 ( Bo Young Kim ),강경원 ( Kyung Won Kang ),최선미 ( Sun Mi Choi ) 경락경혈학회 2011 Korean Journal of Acupuncture Vol.28 No.4

        Objectives: The survey was conducted to find out ear acupuncture usage of clinical traditional Korean medicine doctor and lay a foundation for the standards for its clinical application. Methods: An e-mail was sent to Korean medicine doctors whose email addresses are registered at the Association of Korea Oriental Medicine twice over two weeks. 280 completed questionnaires were used for the analysis. Results: 66.07% of respondents answered in use, whereas the answer that "less than 10 per 100 patient applied" was more than majority of 54.29%. The major field of treatment is addictive disorders such as smoking and the 80.11% patients got less than 3 days of treatment. Ear region was the most commonly treated area with 66.67%. Since the self removal frequency was high as 65.05% in compared to the case of visiting clinic. The rate of side effects was less than 10% (96.70%), and these side effects showed light symptoms such as "pain" (46.95%), itchiness (29.27%), flare (19.51%). The Acquired complements for improving ear acupuncture treatment was "the development of effective treatment manual" (28.57%) and "increasing insurance costs" (27.86%). Conclusions: Based on the survey, the vast majority of the TKM doctor used ear acupuncture but the frequency of use was low. We hope this study can be the basis for development of treatment manuals for various indications and safe treatment guidelines.

      • 백양사 사찰림 비자나무 임분의 테르펜류 잔존량과 성분특성

        김애란 ( Ae-ran Kim ),양천은 ( Cheon-eun Yang ),허예나 ( Ye-na Heo ),김강산 ( Kang-san Kim ),박종석 ( Jong-suk Park ),김은일 ( Eun-il Km ),안기완 ( Ki-wan An ),김민희 ( Min-hee Kim ) 한국산림경제학회 2018 산림경제연구 Vol.25 No.1

        본 연구는 비자나무 임분내의 NVOCs 잔존량을 규명하고 비자나무에서 방출되는 NVOCs의 성분을 규명하고자 수행하였다. 실험은 2017년 4월부터 10월까지, 총 7회에 걸쳐 장성군에 위치한 내장산국립공원 백양지구 내 비자나무 임분에서 이루어졌다. NVOCs의 포집은 가지에 테틀러백을 씌우고 순수공기를 주입시켜 11시부터 12시까지 포집하는 테틀러백 법과 임분 내에서 직접 포집하는 미니펌프법으로 실시하였다. 테틀러백을 이용한 비자나무의 월별 NVOCs 잔존량은 각각 146,156 pptv/4월, 176,786 pptv/5월, 132,466 pptv/6월, 22,908pptv/7월, 73,782pptv/8월, 38,736pptv/9월, 41,233pptv/10월로 측정되었으며, 비자나무 임분 내에서 측정한 월별 NVOCs는 5,169 pptv/4월, 11,940 pptv/5월, 7,657 pptv/6월, 6,864pptv/7월, 13,912pptv/8월, 2,640pptv/9월, 1,828pptv/10월로 나타났다. NVOCs의 15종에 대한 성분을 7회 평균값을 산출한 결과, limonene이 약 43∼52%로 가장 많은 함량을 차지하고 있었으며 α-pinene 은 약 35∼39%의 비율인 것으로 분석되었다. 비자나무를 대상으로 포집방법의 차이에 따른 NVOCs 잔존량은 최소 15배에서 28배까지 차이를 보였으며, NVOCs 성분의 대부분이 limonene과 α-pinene으로 나타났다. 임분내 NVOCs에 대한 기초자료로서 활용될 수 있을 것으로 사료된다. This study aims to identify the NVOCs(Natural Volatile Organic Compound) retention volume of Torreya nucifera stand and the characteristic of chemical compositions of the NVOCs emitted from it. This experiment was performed seven times in total from April to October, 2017 at Torreya nucifera temple forest of Naejangsan National Park Baekyangsa in Jangseong-gun. Two methods were used as the sampling methods of NVOCs. The first one was to use tedlar bags. After placing a tedlarbag over a branch and leafs, we injected pure air into it and captured NVOCs for 2 hours from 11 a.m. to 12 p.m. The second one was to capture NVOCs directly in a stand of Torreya nucifera used mini pump. When tedlarbags were used, the monthly NVOCs retention volumes of Torreya nucifera were 146,156pptv/April, 176,786pptv/May and 132,466pptv/June, 22,908pptv/July, 73,782pptv /August, 38,736pptv/September, 41,233pptv/October respectively. In addition, when measured using minipump in the stand, the monthly NVOCs retention volumes were 5,169 pptv/April, 11,940pptv /May, and 7,657pptv/June, 6,864pptv/July, 13,912pptv/August, 2,640pptv/September, 1,828pptv/October respectively. In order to identify the characteristic of compositions, 15 kinds of terpenes were analyzed, and their average was calculated seven times. As a result, limonene had the highest percentage of 43 to 52%, and α-pinene accounted for 35 to 39%. The NVOCs retention volume depended on the sampling method from Torreya nucifera stand. The highest NVOCs retention volume was at least 15 to 28 times higher, and most components of NVOCs were limonene and α-pinene. It is believed that NVOCs within the domain can be utilized as a baseline.

      • KCI등재

        의도적 간호순회 인식과 배경요인이 이행에 미치는 영향

        김미영 ( Kim Mi Young ),김미순 ( Kim Mi Soon ),김애란 ( Kim Ae Ran ),김희선 ( Kim Hee Sun ) 병원간호사회 2021 임상간호연구 Vol.27 No.1

        Purpose: This descriptive study aimed to explore the performance, nurses' perception, and influencing contexts of intentional rounding (IR), and to identify the factors influencing the performance of IR. Methods: 498 questionnaire responses were collected from clinical nurses with more than six months of work experiences in general wards performing IR in a general hospital. Results: The mean scores of the performance, nurses' perception, and influencing contexts of IR were 3.81(±0.68), 3.46(±0.42), and 3.79(±0.51) out of 5.00, respectively. There were significant differences in performance (F=20.51, p<.001) and nurses' perception (F=4.96, p=.001) based on the work department. There were significant differences in the influencing contexts based on age (F=6.02, p=.003) and the length of clinical experience in the ward (F=3.36, p=.010). Performance and nurses’ perception(r=.42, p<.001), performance and influencing contexts (r=.46, p<.001), and nurses' perception and influencing contexts (r=.58, p<.001) showed a statistically positive correlation. Work unit (F=10.45, p<.001), nurses' perception of the benefits to patients (F=-2.46, p=.014) and to nurses (F=4.34, p<.001), and influencing contexts at the individual (F=7.77, p<.001) and department levels (F=2.99, p=.003) were found to be significant factors on the performance of IR. Conclusion: It is necessary to support the education programs and active participation of nurses in their role as leaders to raise their awareness regarding the benefits of IR. Furthermore, there is a need to adapt the IR protocol according to the unique characteristics of each unit and evaluate the effectiveness.

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