Mulligan의 Sustained Natural Apophyseal Glides Mobilization이 만성 요통 환자의 요부근 활성도에 미치는 효과

김세윤,김난수,Kim, Se-Yoon,Kim, Nan-Soo 대한물리치료학회 2013 대한물리치료학회지 Vol.25 No.1

Purpose: Low back pain occurs and frequently recurs in many people. An imbalance of paraspinal muscle activity can cause low back pain. Mulligan's concept of mobilizations with sustained natural apophyseal glides (SNAG) is a common method for treating low back pain. The purpose of this study was to investigate the effects of this method on paraspinal muscle activity in patients with chronic low back pain. Methods: Twenty-one patients with low back pain participated in this study. Patients were classified using the Oswestry disability index. The subjects' paraspinal muscles were measured by surface electromyography both before and after the SNAG mobilization. We measured the root mean square value of the paraspinal muscles during lumbar flexion and extension. Results: Paraspinal muscle activity in patients with chronic low back pain was different between the right and left sides. Importantly, paraspinal muscle activity significantly decreased after using the SNAG mobilization method. Conclusion: This study shows a difference between paraspinal muscle activity in chronic low back pain patients and finds that the Mulligan's concept of SNAG mobilization is effective at reducing imbalances in paraspinal muscle activity in low back pain patients.

이미지 센서기반의 태양광 자동 추적 시스템 개발

김세윤,안서길,김성호,Kim, Se Yoon,An, Seo Kil,Kim, Sung Ho 한국스마트미디어학회 2014 스마트미디어저널 Vol.3 No.1

전 세계적으로 석유자원의 고갈로 인해 석유가격의 상승 및 중국, 인도 등 거대개도국의 에너지 수요 폭발로 국내외 에너지환경은 새로운 도전과 변화의 국면에 처해 있다. 그러나 태양광 발전은 기존 발전방식에 비하여 발전 단가가 높고 에너지 밀도가 희박하여 일정한 전력을 이용하기 위해서는 넓은 면적의 태양전지모율 설치 장소가 필요하다. 또한 기상조건 및 자연조건에 절대적인 영향을 받기 때문에 태양광 발전의 효율적인 발전을 위해서는 지리적인 위치와 태양의 위치 등을 고려하여 태양전지모듈이 지속적으로 많은 양의 발전을 할 수 있게 하는 기술이 필요하다. 이에 본 연구에서는 기존 추적 시스템의 문제점을 해결하기 위해 새로운 형태의 태양 추적 시스템을 제안하고자 한다. 또한 제안된 기법의 유용성을 확인하기 위해 제작된 시제품에 알고리즘을 구현하여 실제 실험을 수행하고자 한다. Recently, domestic energy environment is facing new challenges owing to the depletion of fossil fuel such as oil. Renewable energy resources including solar and wind energy are attracting more interests than ever before. However, solar power system is costly in comparison with the conventional power generation systems and also the energy density is low. Furthermore, large area is required in order to install solar power system. Generally, performance of solar power system is affected by weather conditions and alignment of sun and the solar cell modules. In this study, a new type of sun tracking system for solar power system is proposed. To verify the feasibility of the proposed system, actual implementation of prototype system and experiments are carried out.

충남 일부 중년 성인의 운동습관에 따른 식습관 및 스트레스 상태

김세윤,서연자,김미현,최미경,Kim, Se-Yune,Seo, Yeon-Ja,Kim, Mi-Hyun,Choi, Mi-Kyeong 한국식품영양학회 2016 韓國食品營養學會誌 Vol.29 No.1

This study aimed to evaluate the health concern, eating habits, dietary behavior, and psychological stress among middle-aged adults in Chungnam according to their exercise status. A total of 437 adults with a mean age of 42.6 years participated in this study and completed a questionnaire survey. The subjects were divided into one of three groups according to their exercise status: never doing exercise (NDE; n=144), doing exercise once a week (DEO; n=186), and doing exercise twice a week or more (DET; n=107). Results demonstrated significant differences in concern about health, subjective health status, meal regularity, dietary problems, and stress score among the three groups. The DET and DEO groups were more concerned about their health (p<0.001), and had a perception that their health status was better than that of the NDE group (p<0.01). A larger percentage of the DET group had breakfast everyday (p<0.05) and a smaller percentage of the DET group had dietary problems such as irregular mealtime and skipping meals (p<0.01), compared to the other groups. The average stress score of the DET group was significantly lower than that of the DEO and NDE groups (p<0.05). The results reveal that doing regular exercising at least twice a week is associated with higher health concern, more desirable dietary habits, and lower psychological stress in middle-aged adults. These findings support the beneficial effects of regular exercise for health, dietary habits, and stress control.

두부 전방전위 자세가 젊은 성인들의 호흡기능에 미치는 영향

김세윤,김난수,정주현,조명래,Kim, Se-Yoon,Kim, Nan-Soo,Jung, Ju-Hyeon,Jo, Myeong-Rae 대한물리치료학회 2013 대한물리치료학회지 Vol.25 No.5

Purpose: Forward head posture is a typical symptom in people who use computers for long periods of time. Respiration is a complex function involving co-operation of muscular, skeletal, and nervous systems. Abnormal posture can have a negative effect on respiratory function. The purpose of this study was to investigate the relationship between forward head posture and respiratory function in young adults. Methods: Forty-six healthy subjects participated in this study. Craniovertebral angle was measured for assessment of the forward head posture. The respiratory function of all subjects was evaluated by measuring forced vital capacity (FVC), forced expiratory volume at one second (FEV1), forced expiratory volume at one second/forced vital capacity (FEV1/FVC) ratio, and peak expiratory flow (PEF). The baseline of forward head posture was less than 49 degrees. Results: : Significant differences for predicted FVC and FEV1 were observed between the two groups, however, no statistically significant differences in FEV1/FVC ratio and PEF were observed between the two groups. Conclusion: Results of this study demonstrate that forward head posture has a negative effect on respiratory function in young adults.

경증 두부외상 환자에서 MR FLAIR 영상의 임상적 유용성

김세윤,황금,김헌주,이명섭,Kim, Sei-Yoon,Whang, Kum,Kim, Hun-Joo,Lee, Myoung-Sup 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.10

Objectives : MR fluid-attenuated inversion recovery(FLAIR) image uses paired long inversion time and relaxation time that nulls the signal from CSF. With nulling of the CSF long echo time readout could be used to increase T2-weighting, hence improving the conspicuousness of most tissue lesions without the deleterious effects of CSF artifact seen on T2 weighted sequence. We examed the usefulness of FALIR image in the diagnosis of mild head injury. Methods : A total of 38 patients with mild head injury were examined by FLAIR image. We compared those images with CT scan and T1, T2-weighted images. Careful observation of MR images were done by two well-trained neuroradiologists. Each image was compared for conspicuousness and detectability of traumatic lesions might have shown abnormal signal intensities. The Wilcoxon signed ranks test was used for statistical evaluation. Results : The FLAIR image was significantly more sensitive than those of other images(p<0.001). T2 FFE(Fast Field Echo) image was more useful for detection of small petechial hemorrhages. Conclusion : FLAIR image is considered to be more sensitive than those of conventional MR images in the evaluation of mild head injuries.

쇄기형 유전체의 앙면에 평면파 입사시 Neumann전개를 이용한 회절패턴 계산

김세윤,나정웅,Kim, Se-Yun,Ra, Jung-Woong 대한전자공학회 1989 전자공학회논문지 Vol. No.

임의의 각을 갖는 쇄기형 유전체의 양 경계면에 E-편파된 입사시 전자파의 회절문제에서 쇄기형 유전체의 모서리 근방에서 정전기적 극한의 모서히 조건을 만족하는 해를 구하였다. 물리광학근사로 구한 회절계수를 유전체 경계면을 따라 분포한 Neumann 전개된 면전류로 교정하였다. 모서리 끝점에 분포한 다극선전원으로 교정된 회절계수에 비하여, 본 논문에서 구한 회절계수는 유전체 내부의 비유전율을 점차 크게 할 경우 좀 더 정확히 쇄기형 완전도체의 회절함수에 접근함을 보았다. The electromagnetic diffraction problem for the incidence of E-polarized planewave on both interfaces of an arbitrary-angled dielectrc wedge is solved in conjunction with the edge condition near the tip of dielectric wedge in the static limit. The diffraction coefficients obtained by the tip of the wedge, the diffraction coefficients presented in this paper approach more closely to the exact pattem of a perfectly conducting wedge as the relative dielectric constants of the dielectric wedge increase.

제 I 형 신경섬유종증에 병발하였던 종격동내 횡문근육종에 의한 척수압박 1례 - 증례보고 -

김세윤,황금,홍순기,변진수,허철,김헌주,한용표,이명섭,이종국,조미연,Kim, Sei-Yoon,Whang, Kum,Hong, Soon-Ki,Pyen, Jhin-Soo,Hu, Chul,Kim, Hun-Joo,Han, Young-Pyo,Lee, Myoung-Sup,Lee, Chong-Kook,Cho, Mee-Yon 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.5

A 12-years-old female admitted to the hospital with the complaint of pain on the right upper chest area which persisted about 1 month prior to admission. $Caf{\acute{e}}$-au-lait spots of various size laying on a whole body and freckling on the axilla were found on physical examination. A huge mass was found on the plain chest X-ray and on chest MRI. The mass encroached thoracic spine, posterior rib, back muscles, and then into the neural canal and compressed thoracic spinal cord. On the 5th day of hospitalization, the patient complained tingling on the both legs and 2 days later, monoparesis on the right leg. Open thoracotomy and decompressive laminectomy was done to remove mass. Pathologic reports confirmed rhabdomyosarcoma, embryonal type.

학교 집단 요검사로 조기 진단된 IgA 신증 환아의 임상적 특징

김세윤,이상수,이재민,강석정,김용진,박용훈,Kim, Sae Yoon,Lee, Sang Su,Lee, Jae Min,Kang, Seok Jeong,Kim, Yong Jin,Park, Yong Hoon 대한소아신장학회 2013 Childhood kidney diseases Vol.17 No.2

목적: 면역글로불린A(IgA) 신증은 다양한 임상양상을 보이는 가장 흔한 원발성 사구체 신염으로, 적극적인 치료로서 단백뇨와 사구체손상을 줄여야한다. 저자들은 학교 집단 요검사를 통해 진단된 IgA 신증의 특징을 알아보고자 하였다. 방법: ${\bigcirc\bigcirc}$대학교병원 소아청소년과에서 조직검사를 받고 IgA 신증으로 진단받은 환자 64명을 내원 당시의 증상 유무에 따라 두 군으로 나누어 후향적으로 연구하였다. 결과: 증상 없이 학교신검에 의해 진단된 37명과 혈뇨 등으로 내원하여 진단된 27명을 대상으로 하였다. 각 군의 평균 연령은 각각 $10.8{\pm}2.7$세 및 $9.5{\pm}3.4$세였고, 각 군 모두에서 남아가 많았다. 증상 발현 후 내원까지의 기간과 조직 검사까지의 기간은 증상군에서 더 짧았다. 임상 증상은 증상군에서 육안적 혈뇨(P<0.001)와 부종(P=0.008)이 더 많았다. 혈액검사에서 증상군의 백혈구 수가(P=0.007) 많았고, 혈색소 값은(P=0.007) 더 낮았으며 BUN과 크레아티닌 값은 차이가 없었다. 혈청 알부민 값은 증상군에서 학교신검군에 비해 더 낮았고(P=0.006), 두 군에서 치료기간은 차이가 없었고, 치료약제는 ACEI가 가장 많았다. 전체 환아군을 대상으로 광학적 신조직 검사분석 시, 육안적 혈뇨기왕력이 있는 군에서 없는 군에 비해 좀 더 심한 병변을 보였으며, 단백뇨의 중증도와 병변의 중증도와는 상관이 있었다. 결론: 학교신검군 및 증상군 모두 조기 진단된 IgA 신증으로 임상적 및 조직학적인 큰 차이를 볼 수 없었다. 학교신검은 조기에 IgA 신증을 선별하는데 유용하지만, 조기진단이 치료나 예후에 어떤 영향을 주는지는 향후 보다 많은 대상자들의 장기간 추적관찰이 더 필요할 것으로 생각된다. Purpose: IgA nephropathy (IgAN) is one of the major causes of end-stage renal disease. Mass school urine screening (SUS) has been performed to enable early detection of chronic renal diseases, including IgAN. We wanted to evaluate the patients with IgAN, including those diagnosed through SUS. Methods: Between 1998 and 2010, 64 children were diagnosed with IgAN based on renal biopsy results obtained at the Pediatric Nephrology Department, ${\bigcirc\bigcirc}$ University Hospital. We divided these patients into the SUS group (37 cases), diagnosed through SUS, and the symptomatic (Sx) group (27 cases), diagnosed clinically. The medical records of both groups were analyzed retrospectively. Results: The mean age of the SUS and Sx groups was $10.8{\pm}2.7$ and $9.5{\pm}3.4$ years (P >0.05), respectively. Both groups had a higher proportion of male patients. The time from the notification of an abnormal urinary finding to a hospital visit or renal biopsy was shorter in the Sx group than in the SUS group. Regarding clinical manifestations, there were fewer cases with gross hematuria (P <0.001) and edema (P =0.008) in the SUS group, but there were no differences in terms of the therapeutic regimen and treatment duration. Regarding laboratory parameters, the Sx group had a higher white blood cell count (P =0.007) and lower hemoglobin (P =0.007) and albumin (P =0.000) levels. There were no differences in the renal biopsy findings in both groups, based on the history of gross hematuria or the severity of proteinuria. However, in all 64 patients with IgAN, the light microscopy findings (Hass classification) were related to a history of gross hematuria or the severity of proteinuria. Conclusion: There were no significant clinical and histological differences between the groups, as both had early stage IgAN. Although SUS facilitates the early detection of IgAN, long-term, large-scale prospective controlled studies are needed to assess the benefits of early diagnosis and treatment in chronic renal disease progression.

소아에서 조혈모세포이식 후 급성 신질환의 분석

김세윤,최정연,하정옥,박용훈,Kim, Sae-Yoon,Choi, Jung-Youn,Ha, Jeong-Ok,Park, Yong-Hoon 대한소아신장학회 2009 Childhood kidney diseases Vol.13 No.2

소아 악성종양환아들의 완치를 위한 조혈모세포이식술이 최근 널리 이루어지고 있다. 하지만 높은 치료율과 더불어 이의 부작용 또한 많이 보고되고 있다. 본 연구에서는 소아에서 조혈모세포이식술 이후의 급성 신질환의 임상적인 특성과 결과에 대해 알아보고자 하였다. 1995년 9월부터 2009년 4월까지 영남대학교 부속병원 소아청소년과에서 조혈모세포이식을 시행한 53명의 환자들을 대상으로 하였다. 조혈모세포이식 3개월 후의 사구체여과율을 계산하여 신장의 기능이 25% 이상 감소한 '조기 신기능 감소군'과 25% 미만 감소한 '조기 신기능 비감소군' 두 군으로 나누어 의무기록을 후향적으로 분석하였다. 환아의 원인 질환은 급성 백혈병과 신경모세포종이 각각 23명과 13명으로 가장 많았고, 그 외 뇌종양 및 기타 고형 종양이 6명, 재생불량성 빈혈이 4명, 악성 림프종이 4명, 골수이형성 증후군이 2명, 선천성 면역결핍질환이 1명이었다. 조혈모세포이식 3개월 후 25% 이상의 사구체여과율이 감소한 환아는 18명이었다. '조기 신기능 감소군'과 '조기 신기능 비감소군'은 각각 18명과 35명이었고, 이식세포 공급원은 제대혈(n=11)이 4명과 7명, 골수(n=16)는 8명과 8명, 자가 말초혈액(n=26)은 6명과 20명으로 차이는 없었다. 골수 및 제대혈 이식을 시행한 27명의 환아에서 급성 이식편대숙주반응은 신기능 감소군과 비감소군에서 차이를 보이지 않았다. 모든 환아는 전처치법 중 1가지 이상의 신독성 항암제를 투여받았으며 전신방사선조사 및 항흉선세포글로불린을 포함한 전처치법에 따른 두 군의 차이는 없었다. 사망한 환아는 '조기 신기능 감소군'과 '조기 신기능 비감소군'이 각각 12명과 10명이었고, '조기 신기능 감소군'에서 사망환아의 비율이 더 많았고, 사망의 원인으로는 감염, 급성 신부전, 재발 등이었고 '조기 신기능 비감소군'에 비해서 '조기 신기능 감소군'에서 급성 신부전이 많았다. 하지만 신장기능의 저하정도에 따라서는 사망한 환아는 차이를 보이지 않았다. 이번 연구에서는 소아에서 조혈모세포이식 3개월 후의 조기 신기능 저하는 18명이 있었으며 조혈모세포이식 후 발생하는 합병증 중 하나인 급성 이식편대숙주반응과 관련이 없었으며 이식세포 공급원과도 관련이 없었다. 조기 신기능 저하를 보인 환아에서 사망한 환아가 많았고, 신장기능 저하가 중요한 사망 원인이었다. 생존한 조기 신기능 저하군의 환아는 모두 신기능을 회복하였으며, 이식 12개월 후 후기 신기능 저하는 1명으로 이식의 합병증과는 관련이 없었으나 이후 이식 6년째에 재발로 사망하였다. Purpose : Stem cell transplantation (SCT) has gained worldwide acceptance as a treatment for hematologic disorders. This study was performed to evaluate the clinical characteristics and outcomes of the acute kidney injury after SCT in children. Methods : The records of 53 patients who were treated with SCT at the pediatric department of Yeungnam University Hospital between January, 1996 and April, 2009 were used as subjects. Their were divided into two groups ; 'Early renal insufficiency' (ERI, n=18) and 'Non-early renal insufficiency' (NERI, n=35). ERI had greater than 25% of drop in GFR after SCT. Results: Total 53 patients were analyzed. In cord blood SCT (n=11), ERI was 4 (36.4%) and NERI was 7 (63.6%). In bone marrow SCT (n=16), ERI was 8 (50.0%) and NERI was 8 (50.5%). In autologous peripheral blood SCT (n=26), ERI was 6 (23.1%) and NERI was 20 (76.9%). There is no difference in both groups according to kinds of SCT. GVHD was developed in 22 patients, and there is no difference in each group. Twenty two of 53 patients died. ERI was 12 (66.7%) and NERI was 10 (28.6%). Acute renal failure is most important cause of the deaths. Conclusion : Out of 53 pediatric patients who were treated with SCT, 18 patients had greater than 25% of drop in GFR. There is no difference in both groups according to kinds of SCT. GVHD was found in 22 patients and there is no relation between GVHD development and acute kideney injury.

삼정환(三精丸)이 대식세포의 면역반응에서 유도되는 $IL-1{\beta}$ 유전자의 발현에 미치는 영향

김세윤,정지천,Kim, Se-Yoon,Jeong, Ji-Cheon 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.1

Objectives : Macrophage has an important innate defense role in the immune system. When we are infected with pathogens, macrophage ingests them through phagocytosis or endocytosis, and then secretes many cytokines, such as IL-1, IL-6 and $TGF{\alpha}$, which are regulators of immune responses. The aim of this study is to determine how Samjunghwan effects the expression of cytokine and other immune-related genes in macrophages. Methods : Cells were treated directly with Samjunghwan and/or LPS at regular intervals. Total RNA of cells was isolated using TRIzol reagent, and the changes in cytokine gene expressions were investigated using RT-PCR, western blot and ELISA. Results : $IL-1{\alpha},\;IL-1{\beta}$ and COX-2 genes were inducibly expressed specifically by Samjunghwan in macrophage. Especially, $IL-1{\beta}$ gene was induced most strongly by treatment with Samjunghwan. Over time, treatment with Samjunghwan showed that the expression levels of $IL-1{\alpha}\;and\;$IL-1{\beta}$ genes increased from 1 to 4h, and then decreased from 4 to ISh. However, the expression level of COX-2 gene increased continuously up to 11h. $IL-1{\alpha},\;IL-1{\beta}$ and COX-2 genes were expressed synergistically by a simultaneous treatment of both Samjunghwan and LPS in macrophages. Secretion levels of translated $IL-1{\beta}$ increased continuously up to 11h. Conclusions : Though this study is only a start in the investigation of the efficasy of Samjunghwan, these results suggest that Samjunghwan has positive effects on immune responses.