비만 개선 효과를 지닌 탄수화물 및 지방 흡수 억제 기능성 식이조성물 개발

윤유식,최선미,홍순복,홍정미,김정원,이홍석,홍성길 한국조리과학회 2002 한국식품조리과학회지 Vol.18 No.3

In a previous study, we developed a new food additive as an egg yolk antibody (IgY) against carbohydrate digestion enzymes for the regulation of blood glucose level and weight control. The IgY delayed and decreased the increment of blood glucose level after administration of sucrose in human being by 30% in 20∼30 min. We also developed a lipase inhibitor as a water extract of two kinds of herb, Platycodon grandiflorum and Solanum melongena. Twenty three volunteers were subjected to the intake of the egg yolk IgY plus the herbal extracts for 50 days. In average, the treated subjects appeared to lose 1.96 ㎏ of body weight and 3.4 ㎏ of body fat mass during the treated period. Furthermore, Panniculus adiposus and breech size were significantly decreased during the experimental period. Above results suggested that the administration of the dietary additives composed of egg yolk IgY and natural herbal extract improve the obesity by the decrement of body weight and body fat mass.

고양이 중뇌 흑색질의 Dopamine 면역반응세포에 관한 면역세포화학적 연구

모근석,문정석,김종중,김준수,정윤영,장인엽,김흥중 대한해부학회 1996 Anatomy & Cell Biology Vol.29 No.5

CORBA 기반 망관리 시스템 통합에 관한 연구

윤채운,김명균,허정석 울산대학교 1999 공학연구논문집 Vol.30 No.2

통신망이 커지고 복잡해짐에 따라 통신망 관리는 더욱 중요해지고 있다. 이러한 통신망을 효율적으로 관리하기 위해 국제 표준화 그룹인 ITU와 ISO는 CMIS/CMIP 기반의 OSI망 관리 모델 [1]을 표준화하고 IAB에서는 SNMP [7] 기반 망관리 모델을 표준화하였다. 이들 망관리 모델은 통신망 요소들의 관리에는 효율적이지만 복잡한 망들의 관리나 서비스 관리에는 많은 문제들이 있다. 이러한 문제들을 해결하기 위해 본 논문에서는 분산 객체 지향 기술인 CORBA[3]를 이용하여 기존의 망관리 시스템들을 통합하기 위한 방법에 대해 기술한다. CORBA 기반 통합 망관리 구조를 제시하고 CORBA와 OSI망관리 모델사이의 관리정보 및 관리기능 변환 기능을 위한 CORBA/CMIP 게이트웨이 구조를 제시한다. 또한 COBRA 관리자에서 OSI객체들을 접근하기 위� 기법과 OSI객체에서 발생하는 이벤트를 CORBA 관리자에 전달하기 위한 기법들에 대해 기술한다. Network management systems become more important as the communications networks evolve larger and more complicated. For the efficient management of the communications networks, the international standard organizations, ITU and ISO, have standardized OSI network management model [1] based on CMIS/CMIP, and IAB has proposed SNMP [7]as the Internet management model. The traditional management models are efficient in managing simple communications netwrks, but have many problems in managing complicated networks and services. To solve those problems, this paper proposes an integration method of network management systems based on CORBA [3] which is a distributed and object-oriented technology. We describe an integrated network management architecture based on CORBA/CMIP gateway. The CORBA/CMIP gateway converts the management systems. We also describe how the CORBA managers access the OSI managed objects and how the events occurred in the OSI managed objects are delivered to the CORBA managers.

운동형태의 차이가 Alloxan유발 당뇨쥐의 혈당 및 인슐린 농도에 미치는 영향

윤진환,정일규,김종오,이희혁,지용석,오봉석,채정룡 대한스포츠의학회 2003 대한스포츠의학회지 Vol.21 No.1

The Purpose of this study was to investigate the effect of exercise intensity on blood glucose and insulin levels in diabetic rats with alloxan. Twenty sprague-dawley male rats were assigned to power training groups(n=10) and endurance training groups(n=10). Diabetes was induced by single injection of alloxan(50 mg/kg B.W) Blood glucose and insulin were determined every week for 4-weeks. The conclusion of this study follows as below: 1) There was significantly different on blood glucose levels in two groups. 2) There was significantly different on insulin levels in two groups These results suggest that proper exercise intensity in diabetic rats can significantly decrease blood glucose and insulin level and make good glycemic control. In conclusion, it has been found that regular prolonged endurance training with diabetic rats, improves insulin and blood glucose.

흰쥐 뇌에서 Neuropeptide-Y 분비세포의 출현시기 및 발육에 관한 면역조직화학적 연구

모근석,김종중,정윤영,장인엽,문정석,김준수,김흥중 대한해부학회 1996 Anatomy & Cell Biology Vol.29 No.5

실시간 분산 환경 감시를 위한 TMO 모델의 연구

정윤석,김태완,장천현 건국대학교 산업기술연구원 2005 건국기술연구논문지 Vol.30 No.-

We need an additional monitoring tool to observe a TMO model-based system because the conventional tools ae not based on the monitoring concept. Some studies have been conducted to develop a monitoring tool. But it is hard for them to support a distribued monitoring because they did not use a data sharing and delivery mechanism provided by the TMO model. To solve this problem, in this paper, we propose a TMO monitoring model which the TMO model and a monitoring concept are combined in. The model is composed of some components to support monitoring, and it guides the middleware to take all the monitoirng functions. Thus, a user can get monitored data provided by the middleware without any efforts. In addition, in this paper, we propose the MODS and MDC which are mechanisms to share or deliver the monitored data in distributed environments. These can resolve problems with conventional data stores used by the legacy monitoring tools, and provide a fundamental data management scheme to monitor several systems in distributed environments. The TMO monitoring model, MODS, and MDC can be used for a TMO system monitoring, performance evaluation, and monitoring tool development.

도파민 치료와 연관된 딸꾹질 1예

하윤석,김민정 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.2

Drug induced hiccups may be associated with a various agents, including corticoste-roid, antibiotics, and benzodiazepines. Rarely, levodopa or dopamine agonist therapy in Parkinson’s disease patient, can trigger hiccups. We report a case of persistent hiccup, occurring with dopaminergic medication in a patient with Parkinson’s disease 약물 유발성 딸꾹질은 코르티코스테로이드, 항생제 그리고 벤조디아제핀 등의 약물에 의하여 발생할 수 있다. 드물게 파킨슨병의 치료 목적으로 사용하는 레보도파나 도파민 효현제가 딸꾹질을 유발시킬 수 있다. 저자들은 파킨슨병의 치료 목적으로 레보도파와 도파민 효현제를 사용한 환자에서 조절되지 않는 딸꾹질을 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

역도 용상 Clean 동작에 관한 연구

윤정환,이석구 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.4

In this study elite male university athletes lifts the weight 95% of MBW for each athletes, For the foot pressure measurement systems were used to analyze changes in kinetic variables related to Clean movements, and the following conclusions were obtained. 1. For the Clean movement among all subjects, the maximum foot pressures were 1.6 and 1.9 times greater than the sum of one's own weight and the barbells weight during the first pull and lock-out, respectively. 2. Pressure was mostly distributed at the toes and the front part of the sole in exerting strength actively as in Pull movement and it was evenly distributed in the entire sole in bearing load passively as in lock-out movement.

Superconducting MgB2 Wire Drawing Considering Anisotropic Hardening Behavior and Hydrostatic Effect

Young‑Seok Oh,Ho Won Lee,Kook‑Chae Chung,Duck‑Young Hwang,Seong‑Hoon Kang,Jeong Whan Yoon 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.7

Numerical modeling was conducted to investigate the deformation behavior of powder mixture during multi-pass drawingprocesses for multi-filamentary MgB2wire. A modified Drucker-Prager Cap (DPC) model with an elliptical cap surface usingthe new material characterization method was developed to capture the anisotropic hardening behavior and hydrostatic effectof the powder mixture. A number of uniaxial die compaction, cold isostatic pressing, diametrical compression, and uniaxialcompression tests were conducted using different powder densities to characterize the modified DPC model. A commercialfinite element software ABAQUS with a user subroutine was used to simulate the drawing of the MgB2wire. The densityand area fraction of the powder mixture during the wire-drawing process were verified with experimental results. The differencein packing density at the inner and outer filaments of the MgB2wire was successfully captured by simulation. Inaddition, the effect of the initial packing density on the superconducting properties of MgB2wire was numerically studied. It is shown that the increase in the superconducting area, which results from a high initial packing density, should be moreeffective compared to the increase in the grain connectivity in enhancing the critical current properties for the MgB2wirewhen the final packing density is saturated after a number of drawing processes.

LC-ESI-MS/MS를 이용한 생체시료 중 브롬화피나베리움의 고감도 분석 및 이를 이용한 생체이용률 평가 : Applicability to Oral Bioavailability Determination

박석,이예리,김호현,이희주,김윤균,염정록,한상범 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.6

A sensitive method for quantification of pinaverium bromide in human plasma was established using liquid chromatography-electrospray ionization tandem mass spectrometrv(LC-ESI-MS/MS). Glimepiride was used as internal standard. Pinaverium bromide and internal standard in plasma sample were extracted using tert-but}lmethvlether(TBME). A centrifuged upper laver was then evaporated and reconstituted with mobile phase of acetonitrile-5 m1VI ammonium formate (8020. pH 3.0). The reconstituted samples were injected into a C_(18) reversed-phase column. Using MS/MS with multiple reaction monitoring (MRM) mode. pinaverium and glimepirde were detected without severe interference from human plasma matrix. Pinaverium produced a protonated precursor ion ([M+H]^(+)) at m/z 510.3 and a corresponding product ion at m/z 228.9. Internal standard produced a protonated precursor ion ([M+H] ^(+)) at m/z 491.5 and a corresponding product ion at m/z 352.0. Detection of pinaverium bromide in human plasma was accurate and precise. with limit of quantitation at 0.5 ng/ml. The method has been successfully applied to bioavailability study of pinaverium bromide tablet in Korean healthy male volunteers. Pharmacokinetic parameters such as AUCr. C_(max) T_(max). K_(el) and t_(l/2) were calculated.