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      • 체간미주신경절단술 및 유문성형술, 선택적미주신경절단술 및 유문성형술과 벽세포 미주신경절단술후 Histamine 자극이 위산분비에 미치는 영향에 관한 실험적 연구

        김인수,김세민 고려대학교 의과대학 1984 고려대 의대 잡지 Vol.21 No.1

        The goal of the therapy for peptic disease is to reduce the acid-pepsin secretion in ther stomach and the recurrence rate, and the parietal cell vagotomy is believed to be a suitable operation for this purpose. The purpose of this study is to report on the response of the gastric secretion after variable vagotomy procedures and to compare the response rate with the administration of histamine in each vagotomy procedures. The author carried out an experimental study on the gastric secretory response to histamine in total 23 mongrel dogs, 8 control group (gastrostomy), 5 truncal vagotomy with pyloroplasty group; 5 selective vagotomy with pyloroplasty group and 5 parietal cell vagotomy group. Gastric juice analysis was carried out 3 times on a monthly with the administration of histamine. The result are as follows: 1. In group of truncal vagotomy with pyloroplasty, the mean value of free acidity after 1 month, 2 month and 3 month of operation decreased by 70.4% 47.1% and 83.1% respectively in comparison with control group, and mean value of total acidity decreased by 32.1%, 24% and 53.1% respectively. The mean value of histamine-responded free acidity after 1 month, 2 month and 3 month of operation decreased by 24%, 43.7% and 48.3% respectively in comparison with control group and mean value of total acidity decreased by 9.4%, 21.2% and 38.8% respectively. 2. In group of selective vagotomy with pyloroplasty, the mean value of free acidity after 1 month, 2 month and 3 month of operation decreased by 18.5%, 41.3% and 25.9% respectively, in comparison with control group. The mean value of histamine-responded free acidity after 1 month, 2 month and 3 month of operation decreased by 27.1%, 45.4% and 46.5% respectively, in comparison with control group and mean value of total acidity decreased by 24.0%, 18.7% and 8.4% respectively. 3. In group of parietal cell vagotomy, the mean value of free acidity after 1 month, 2 month and 3 month of operation decreased by 40.7%, 70.4% and 57.7% respectively, in comparison with control group and mean value of total acidity decreased by 24.0%, 18.7% and 8.4% respectively. Then mean value of histamine-responded free acidity after 1 month, 2 month and 3 month of operation decreased by 33.7%, 25.1% and 63.8% respectively, in comparison with control group and mean value of total acidity decreased by 24.9%, 21.8% and 28.8% respectively. 4. In summary, average reduction rates of free acidity in truncal vagotomy with pyloroplasty, selective vagotomy with pyloroplasty and parietal cell vagotomy were 66.7%, 29.2% and 56.3% respectively, and average reduction rates of total acidity, 36.4%, +10.1% and 28.4% respectively. Average reduction rates of histamine-responded free acidity were 28.7%, 39.5% and 40.9% respectively, and histamine-responded total acidity, 23.1%, 17% and 25.2% respectively.

      • 인공방광대치술을 받은 환자에서의 대사 산증 발생

        김새인,이동현,김광현,류동열,김승정,강덕희,최규복,이신아 이화여자대학교 의과학연구소 2015 EMJ (Ewha medical journal) Vol.38 No.3

        Objectives: Metabolic acidosis frequently develops in patients after neobladder reconstruction. However, the incidence of metabolic acidosis in patients with neobladder and the factors associated with the development of metabolic acidosis have not been well elucidated. We aimed to investigate the incidence and the potential predictors for the development of metabolic acidosis after neobladder reconstruction with intestinal segment. Methods: We included patients who underwent neobladder reconstruction using intestinal segment at Ewha Womans University Mokdong Hospital between January 1, 2005 and December 31, 2014. A subgroup of patients according to the time of metabolic acidosis occurrence was further analyzed in order to characterize predictors for metabolic acidosis. Results: Metabolic acidosis was encountered in 79.4% of patients with neobladder during follow up period. When patients were divided into 2 groups according to anion gap (AG), total CO2 (18.9±2.1 mEq/L vs. 20.0±1.3 mEq/L, P=0.001) and chloride (106.6±4.9 mE/L vs. 109.4±3.6 mEq/L, P<0.001) were significant different between groups with AG>12 and AG≤12. Furthermore, when patients were divided into 3 groups; patients with metabolic acidosis at postoperative day (POD) 1; from POD 2 to 14 days; after 14 days, there was significant difference among those subgroups. Conclusion: Our study showed the rate of metabolic acidosis in patients underwent neobladder reconstruction and the difference between patients with metabolic acidosis and those without metabolic acidosis for the first time in Korea. In the future, well designed prospective study will be needed to prevent metabolic acidosis after neobladder reconstruction.

      • 오리 鼻腔 및 鼻粘膜上皮의 計測에 관한 硏究

        金世仁,金武剛,申台均,金弘善,柳時潤,李永浩 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.1

        The area of the various epithelial types linging the nasal navity of each six number in 1-week-old and 10-week-old adult ducks has been made for the light microscopic research. Transverse sections of 10 microns thick in each specimen were made continuously from the anterior end of nostril to the posterior end of pharyngeal inlet and specimen samples were selected at 0.13mm(1-week-old) and 0.17mm(10-week-old) intervals from the anterior end of the nasal cavity to the posterior end of pharyngeal inlet. The results obtained from research were summarized as follows. 1. The nasal cavity is lined with stratified squamous, respiratory and olfactory epithelium. The thickness of stratified squamous, respiratory and olfactory epithelium is 10-100㎛, 8-75㎛ and 50㎛ respectively in 1-week-old ducks, and 25-175㎛, 20-125㎛ and 66㎛ respectively in 10-week-old ducks. 2. The unilateral volumes of the nasal cavity in 1-week-old and 10-week-old ducks were 21.73±2.64㎟, 1,692.44±171.57㎟ respectively. 3. The total unilateral surface areas of the nasal cavity in 1-week-old and 10-week-old ducks were 70.44±4.92㎟, 1,772.45±94.10㎟ respectively. 4. Each area of the stratified squamous epithelium, respiratory epithelium and olfactory epithelium in unilateral nasal cavity is 14.82±1.85㎟ (21.1%), 46.86±3.20㎟ (66.5%) and 8.76±0.40㎟ (12.4%) in the 1-week-old ducks, and 348.23±40.02㎟ (19.7%), 1,282.31±47.03㎟ (72.3%) and 141.90±12.43㎟ (8.0%) in the 10-week-old ducks. Ducks are assumed as a microsmatic animals by the composition of the lining epithelium of the nasal cavity in ducks.

      • 알콜의 연속투여가 수면구조와 일부 정동에 미치는 영향

        김세인,신석철,왕성근 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

        To investigate the effects of short-term administration of alcohol on the sleep patterns and subjective physiological function(some aspects of emotion), the author applied polysomnography, reaction time and visual analogue test to the volunteer male students. The subjects were 8 healthy young adults, ranging in age from 21 to 26 years, without personal past nor present histories of singificant medical, neurological, or psychiatric illness and suffering from no current major sleep disturbances or parasomnias. After one night sleep of adaptation, each subject was ingested alcohol(43% whisky 3ml/kg) for 5 successive nights and was withdrawn for 3 days, and polysomnography was recorded in the sleep laboratory. Also, reaction time was performed and visual anlogue test were applied to measure the degree of fatigability, mood, and sleepiness for 5 times a day(at 9 : 00, at noon, at 15 : 00, at 18: 00 and at 21 : 00). The results were summarized as follows. 1. Compared with the baseline, sleep latency was significantly shortened during the period of alcohol drinking, and the absolute value(minutes) of stage 3, 4 sleep and SWS, and the relative value(%) of stage 4 sleep were increased significantly in the third drinking night. 2. REM latency was significantly increased in the third and fifth drinking night, and there were no significant change in REM number, REM cycle, and REM duration. 3. There was a significant positive correlation between all the period of drinking and withdrawal nights and the baseline on WASO(waking time after sleep onset), and a significant positive correlation between the 1st, 3rd and 5th drinking night and the baseline on the absolute value(minutes) of SWS and a significant positive correlation between the 3rd and 5th DN and the baseline on the relative value(%) of SWS. 4. Compared with the baseline, feeling of fatigue was significantly severe in the 3rd and 5th drinking day and in the 1st withdrawal day, and there was no difference in the 3rd withdrawal day. 5. Compared with the baseline, mood was significantly worse in the 3rd and 5th drinking day and in the 1st withdrawal day, and there was no difference in the 3rd withdrawal day. 6. Compared with the baseline, sleepiness was significantly increased in the 3rd and 5th drinking day and in the 1st withdrawal day, and there was no diffenence in the 3rd withdrawal day.

      • 자기개방성 증진을 위한 3D 상담 플랫폼 제안 - 20대의 심리상담 인식 개선을 중심으로

        김새별(Sae-byeol Kim),박규희(Gyu-hee Park),신수영(Su-young Shin),장혜린(Hye-rin Jang),조유정(Yoo-jung Cho),최종인(Jon-in Choi),박수이(Su-E Park) 한국정보통신학회 2022 한국정보통신학회 종합학술대회 논문집 Vol.26 No.1

        코로나19 이후 현대인이 겪는 정서적 문제가 높아지는 가운데, 심리상담에 대한 부정적 인식과 물리적 한계로 인한 내담자의 부담은 여전히 높다. 이에 본 연구는 비대면 관계에서 관계에 개방적인 20대의 특성을 이용하여 효과적인 상담을 위한 가상 심리상담 플랫폼을 제안하고자 한다. 이를 위해 20대를 대상으로 설문조사를 실시하고 상담사와의 심층 인터뷰를 진행하였다. 이후 Unity를 통해 3D 가상 상담 환경을 조성하여 PC 기반의 서비스를 구상하였다. 연구 결과, 20대가 상담에서 가장 중요하게 생각하는 요소는 상담사의 성향과 부담감 없는 분위기로 나타났으며 이는 심리 상담에서의 자기개방과 밀접한 관련이 있는 것으로 드러났다. 따라서 편안한 분위기로 조성된 3D 공간에서 상담사 캐릭터를 보며 상담에 참여할 수 있도록 하였고 상담 중 상담사와의 다양한 인터랙션 요소를 제공하였다. 본 연구의 의의는 20대 내담자의 자기개방성을 증진해 내담자의 적극적인 상담 참여를 목표로 한다. 이는 원활한 상담을 통해 심리 문제 개선에 큰 도움을 줄 것으로 보인다. As the emotional problems experienced by modern people after COVID-19 have increased, the burden on clients due to negative perceptions of psychological counseling and physical limitations is still high. Therefore, this study proposes a virtual counseling platform for effective counseling using the characteristics of people in their 20s who are open to relationships in non-face-to-face relationships. To this end, a survey was conducted for those in their 20s and in-depth interviews with counselors were conducted. After that a 3D virtual counseling environment was created through Unity to PC-based service. As a result of the study, it was found that the most important factor in counseling in the 20s was the tendency of counselors and an atmosphere without burden, which was closely related to self-opening in counseling. Therefore, it was possible to participate in counseling while looking at the counselor character in a 3D space created in comfortable atmosphere, and various interaction elements with the counselor were provided during counseling. The significance of this study aims to promote self-openness of clients in their 20s and actively participate in counseling. This is expected to greatly help improve psychological problems through counseling.

      • 간세포암과 감별이 어려웠던 악성중피종 치험 1예

        김선문,허원석,채경훈,강윤세,정재훈,김연수,박기오,문희석,이엄석,김석현,성재규,이병석,이헌영,신경숙,조준식,송인상,강대영 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

        Malignant peritoneal mesothelioma is a rare neoplasm that arises from the mesothelium of a serosal cavity and is a rapidly fatal disease with a median survival of 4 to 12 months for untreated cases. Recently, we experienced a case with malignant peritoneal mesothelioma who was suspected hepatocelluar carcioma by abdominal CT scan and was confirmed by biopsy including immunohistochemical stain(calretinin) after surgery. We performed tumor excisions and wedge resection of the liver(segment Ⅷ)and inserted Tencoff catheter in abdominal cavity at 25th day of post-operation. We treated with intraperitoneal paclitaxel(25mg/m^(2)/day for 5 days) six courses monthly. She was well tolerable and is still living without any evidence of recurrence for 14th month of post-operation.

      • 춤의 대중화를 위한 춤 스폰서십의 이론적 고찰

        김인형,김세정,이근모 釜山大學校 附設 體育科學硏究所 1999 體育科學硏究所 論文集 Vol.15 No.-

        The purpose of this study was to provide a grounding model on the activation of dance sponsorship for the popularization of dance as researcher examined a social function of dance, the need of dance sponsorship, and a benefit of dance organization or enterprise by the dance sponsorship. The dance sponsorship can offer a chance which can approach to the general public with a guarantee of financial stabilization to the dance organization. Also, the enterprise can attain a image enhancement, an advertising impact, a sales promotion, or a development of regional economy as well as a profit pursuit of enterprise. On the idea of mutual benefit, the enterprise be able to sponsor a dance in two ways. First, the enterprise is to offer a human or material resources in culture event related dance. Second, the enterprise is to manage directly the dance organization. Therefore, the enterprise can contribute the popularization of dance and play a role of priming for a development of dance culture inducing an interest and participation of the general public at the market of dance arts through a substantial sponsorship like above ways.

      • 천연 고미물질이 김치의 숙성에 미치는 영향

        박인경,서기용,김순동 대구효성가톨릭대학교 식품과학연구소 1997 식품과학지 Vol.9 No.-

        고미물질이 함유된 상치, 쑥갓, 치커리를 첨가한 김치를 10℃에서 숙성시키면서 pH, 산도, 색상, 관능검사를 실시하였다. 그 결과 대조구보다 고미물질 첨가군이 pH는 보다 높게, 산도는 보다 낮게 유지되었고 색상의 변화에 있어서도 뚜렷한 차이는 없었으나 고미물질 첨가군이 양호하였으며 신맛과 종합적인 맛을 평가한 관능검사에 있어서도 고미물질첨가군이 신맛의 증가가 낮으면서도 시원한 맛과 상큼한 쓴맛으로 인해서 종합적인 맛도 좋은 것으로 평가되었다. The effects of some vegegables containing bitter substance(VCBS) such as lettuce, crowndaisy, chicory on the quality and shelf-life of kimchi were investigated. The changes in pH, acidity, color, sensory quality such as sour, overall taste were determined during fermentation. The decrease in pH and increase in acidity were lower in the kimchi added VCBS than in control products. There were no differences in color changes between the kimchi added VCBS and control products during fermentation. The kimchi added VCBS was higher score than control products in sour and overall taste. These results suggest that addition VCBS was observed to influence the shelf-life and quality of kimchi.

      • KCI등재

        한국 20∼30대 여성의 패션 프레임과 패션이미지 유형화

        신세영(Sae Young Shin),김영인(Young In Kim) 한국복식학회 2013 服飾 Vol.63 No.4

        The purpose of this study is to take a look at the fashion frame of Korean women in their twenties and thirties to sort the actual fashion image and the ideal fashion image according to the fashion frame of Korean women in their twenties and thirties, and also to find out the standards and features that divide such a classification. For this study, we used the Q method, which is valued as an effective way to assess subjectivity. This helps to objectively classify the perception the fashion images of and the response to them as well. The analyzed materials were divided into two actual fashion frames and two ideal fashion frames, and classified them into 12 fashion image types in total, that is, six actual fashion images and six ideal fashion images, and we named each type of the fashion images and analyzed the features of each fashion image type through the in-depth Q workshop in which 14 professionals participated. The results of this study are as follows: First, the actual fashion frames of Korean women in their twenties and thirties was largely divided into ``Fashion Gold Girl``, the fashion frame of mainstream and ``Indi-idol``, the fashion frame of subcultures, and this was further divided into six fashion image types: ``Basic Casual``, ``Vintage Performer``, ``Easy Chic``, ``Ladies`` Look`, ``City Office Girl`` and ``Club Mania``. Second, the ideal fashion frame of Korean women in their twenties and thirties was divided into ``Urban Refinement``, the fashion frame of the mainstream and ``Mismatched Style``, the fashion frame of subcultures. It was also divided into six fashion image types: ``Power Fashion``, ``Fashion Conservative``, ``Semi-culture``, ``Fashion Otaku``, ``Sweet Darling`` and ``Fashion Panic``. Third, The characteristics of the fashion images`` colors are recognizable according to the type of fashion images.

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