유기용제 사용 소규모사업장의 체계적 건강관리 프로그램 개발에 관한 연구1) : 신경행동학적 검사법의 적용 가능성 Application of Neurobehavioral Core Test Battery(NCTB)

한상환,하미나,권호장,윤덕로,조수헌 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.2

It is known that there appear some nonspecific and delicate changes in neuropsychiatric aspect on the workers when they are exposed for a long period to low concentrated organic solvents in the work places. Therefore, it gives rise to the necessity of developing a program for the health supervisor stationed in the work place to supervise these neurobehavioral health affection. In addition to the questionnaire posed to the workers exposed to organic solvents, the study team conducted NCTB(Neurobehavioral Core Test Battery) respectively on an exposed group and a non-exposed group to organic solvents. The study team compared the results and decided whether or not to apply the results to the evaluation program of health affection. The study team divided 132 workers in 6 car repairing factories and 2 textile printing factories into exposed group and non-exposed group, pairing them off into 66 research objects according to their age, sex, and job. Neurobehavioral test was conducted on 6 items, except the POMS test, of NCTB developed by the World Health Organization(WHO). The study team conducted examinations of working environment on the exposed and non-exposed groups of each work place. The analysis of the collected materials for examinations were conducted with GC-MS. The concentration of the mixture in the air, relative to their respective threshold limit values(TLV) was calculated according to the formula of the ACGIH and the Korean threshold limits. The results indicated that for two of eight factories samples the recommended concentration limits for mixtures was exceeded. Of the six tests, the 'digit span forward', 'digit span backward' and 'digit symbol' produced conspicuous statistical differences between the two groups(p<0.1) as a result of compairing the test values by means of paired t-test. The results of respective analysis of the car repairing factories and textile printing factories revealed that the textile printing factories had greater differences between the exposed and the non-exposed than in the car repairing factories. It is presumably because the textile printing workers are continuously exposed to the organic solvents during working hours, whereas the car repairing workers are exposed only when they are doing painting works, The NCTB is assessed very useful in examining the neurobehavioral health affection under the exposure to organic solvents, and, therefore, the study team expects that the NCTB will play an important part in the course of developing a health program for the workers exposed to organic solvents.

특수건강진단 자료를 이용한 소음성난청 판정기준의 비교

한상환,조수헌,주영수,하미나,윤덕로,권호장,강대희,성주헌 大韓産業醫學會 1996 대한직업환경의학회지 Vol.8 No.3

Although noise-induced hearing loss (NIHL) is the most prevalent occupational disease in Korea, only 10% of the diagnosed cases are compensated. Old (1989-94) and current diagnostic criteria, criteria for workers' compensation of NIHL in Korea, compensation formulas of American Medical Association/American association of Ophthalmology and Otolaryngology (AMA/AAOO), the Committee on Hearing, Bio-Acoustics, Biomechanics (CHABA), American Academy of Otolaryngology (AAO) recommendation were compared. Each criterion was applied on the audiomety data of 4044 workers (8023 ears), who had received the second line screening test of Special Periodic Health Examination Program for noise-exposed workers during 1991-2. First, the resulting proportions of NIHL cases by employing each criterion were compared and strength of agreement was measured using kappa value. Temporary Threshold Shift (TTS) was corrected by noise free interval, and the reduction ratio of NIHL cases was calculated. Theoretical progression model of NIHL was reconstructed from previous studies on the natural course of NIHL to evaluate the change of diagnosis result of each criterion in the model. The kappa value between old and current criteria was 0.19, 0.55 for current criteria and workers' com. criteria, ranging from 0.08 to 0.78, highest coincidence was observed between current criteria and CHABA formula. The current criteria produce most similar results with CHABA formula. If TTS is corrected for NFI, there is about 14% reduction of NIHL cases. The results of applying on NIHL progression model divided the formulas roughly into 3 groups, of which compensation criteria was the most, old criteria and AAO the least conservative. In conclusion, the result of 4 ㎑ audiometry should be excluded in evaluation of hearing level and a new hearing conservation program should be set out. Current diagnostic criteria has an ambiguity in that managerial concept for prevention and purpose of compensation is mixed up. The current diagnostic criteria and compensation criteria could be incorporated into a new formula which is based on the state of the art test for estimating everyday hearing disability.

자궁 경부의 상피내암, 침윤이 있는 상피내암과 침윤성 편평상피암에서 p53, Ki-67 및 HER-2/neu의 표출 양상

장우섭,오미혜,양승하,김의한 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

To observe the expression of p53, Ki-67 and HER-2/neu in uterine cervical lesions, such as 10 cases of carcinoma in situ(CIS), 7 cases of carcinoma in situ with stromal invasion and 8 cases of invasive squamous cell carcinoma without carcinoma in situ, and to evaluate the corrleationship between results, the author has been carried out immunohistochemical staining with monoclonal antibodies to p53, Ki-67 and HER-2/neu. So, following results are obtained. 1. The p53 show negative reaction in all cases of CIS, and similar patterns in CIS with stromal invasion and invasive squamous cell carcinoma. 2. Ki-67 show high proliferation pattern in all cases and the basal cell show proliferating activity. 3. HER-2/neu show higher score in area of CIS than invasive area in stroma. 4. The stain pattern of HE-2/neu and p53 appeared to be inverse proportion to each other

공동주택 리모델링 계획기법과 거주자 선호도에 관한 연구 : 주동차원의 시행방안을 중심으로

김미영,장한두,제해성 대한건축학회 2003 대한건축학회논문집 Vol.19 No.11

The purpose of this study is to analyze design alternatives for apartment remodeling, and to find out the applicability of the alternatives to real projects, and to find out residents' preferences and needs on them. This study suggests a direction of remodeling design and hopes to vitalize remodeling projects in Korea. This study categorizes types of remodeling design alternatives after analyzing 28 cases of foreign and domestic remodeling projects. The design alternatives are reviewed to check legal accordance of remodeling project. The survey employed questionnaires and interviews, and was performed at five deteriorated apartments at Gangnamgu, Seoul. The selection of apartments are based upon floor area ratio, period of living and so on. First, the study finds out that the residents prefer additional rooms, extension of existing balconies, and extending rooms to balconies. Second, they want to convert corridor type apartment to staircase type (core type) for efficient use of interior space. Third, the residents at top floors wish not to have public roof gardens and those at ground floor want to install private gardens in front of their units.

고등학생 흡연자와 비흡연자의 1일 영양소 및 간식 섭취

송영미,한장일,김성애 대한지역사회영양학회 2008 대한지역사회영양학회지 Vol.13 No.4

This study investigates the relationship of smoking on daily intake of nutrients and snacks in the Chungnam and Daejeon high school students. Up to date scientific nutrition education and counseling programs in the regular school system is needed for a professional nutrition education teacher. The primary objective of this study was to provide useful information to nutrition education teachers. A survey was conducted with 400 high school students in the Chungnam and Daejeon areas. 381 out of 400 questionnaires were analyzed with SPSS 12.0K. The subjects were composed of 49.8% male, 50.1% female and 40.9% regular high school students, 59.1% business high school students and smokers 43.1%, non-smokers 56.9%. 43.4% of smokers had been smoking since middle school. On analysis of daily nutrient intakes, 16 out of 19 nutrients except animal calcium, Vitamin A and Vitamin C were much more consumed by the smoking group than the non-smoking group non-significantly. Especially vegetable fat and Vitamin E were higher in the smoking group than the non-smoking group (p < 0.05). The intake ratio of carbohydrates: protein: fat was similar in the two groups (smoking group 55 : 15 : 29, nonsmoking group 56 : 15 : 28). Intakes of Vitamin B1 and potassium in comparison with the Korean dietary reference intakes (KDRI) were under 50% in both groups. However, sodium was taken over 200% compared to KDRI in both groups. Intakes of Vitamin C in the smoking group were as low as 76.5% in comparison to KDRI. Smokers need to increase the intakes of Vitamin C considering that smokers need to intake Vitamin C two times than non-smokers. Nutrient intakes from snacks in the smoking group were higher than the non-smoking group. Nutrients that originated from snacks which took over 20% among daily nutrient intakes were 12 nutrients (energy, fat, carbohydrate, calcium, P, Fe, K, Vitamin B1, Vitamin B2, Vitamin C, Vitamin E, dietary fiber) in the smoking group compared to 7 nutrients (energy, vegetable protein, fat, carbohydrate, calcium, Vitamin B, Vitamin C) in the non-smoking group. The smoking group was significantly paying more money for snacks each month than the non-smoking group was (p < 0.01). Periods of consumption were irregular in the smoking group (p < 0.05) and the smoking group was used to taking snacks in the morning compared to the non-smoking group. The smoking group preferred sweets and high calorie food over other snacks in comparison of the non-smoking group. The nonsmoking group had better eating habits than the smoking group.

‘숙명역사관’뮤지엄 아이덴티티 개선을 위한 마케팅, 디자인 전략 수립 -특별 기획전, 홍보, 기프트 샵을 중심으로-

박민지,박한빛,서예원,이진민,장미정,이성애 숙명여자대학교 산업디자인연구소 2017 숙명디자인학 연구 Vol.24 No.-

본 연구는 디자인과 마케팅이 이분법적으로 나누어질 수 없음을 인식하고, 디자인과 마케팅을 융합하여 스페이스 디자인 마케팅을 통한 뮤지엄아이덴티티를 구축하는 일련의 프로세스를 제안하는데 목적이 있다. 본 연구는 2017년 3월~6월 총 15주간 숙명여자대학교 환경디자인과 ‘브랜드·스페이스·마케팅’수업에 서 진행된 결과물로서 작업물을 정리하였다. 본 연구의 범위는 4개(物, 事, 人, 場)의 주제 중, 장소(場)를 중심으로 ‘숙명역사관’의 그래픽, 제품, 공간을 개발하는 브랜드 매뉴얼과 연관하여 한정한다. 이에 본 연구는 ‘숙명역사관’이 가지고 있는 역사적 컨텐츠와 가치를 통해 현재 상황과 문제점을 분석하였다. 그 결과 ‘숙명역사관’의 다양한 마케팅 전략을 제시하고 이에 따른 디자인 전략과 해결 방안을 통해 디자인과 마케팅의 융합을 꾀하였다. 아울러 SWOT 분석을 통해 로고, 명함부터 새로 기획하는 숙명역사관 기프트샵, 인테리어디자인, 디스플레이, 공간연출과 그 안의 제품디자인에 이르기까지 일관성과 통일성을 추구했다. 끝으로 본 연구는 뮤지엄아이덴티티 구축을 위한 창의적 디자인 프로세스를 고찰하며, 이를 바탕으로 개발 매뉴얼을 총체적으로 정리함에 있어서 뮤지엄 브랜딩의 기초 자료로 활용될 것으로 기대된다.

온라인 전자 지도안 시스템의 구축 및 활용에 관한 연구

천종필,백장미,한선관,이철환 한국컴퓨터교육학회 2003 컴퓨터교육학회 논문지 Vol.6 No.1

본 연구자들은 ICT 활용 교육을 위한 초등교육 지도안을 온라인상에서 작성하고 활용할 수 있는 Web기반 전자지도안 시스템을 개발하였다. 개발된 온라인 전자지도안 시스템 은 ICT 교수-학습 과정안 자료를 데이터베이스화하여 체계적으로 관리할 수 있도록 하였으며, 교수-학습 과정안의 공유, 활용, 저장성의 극대화를 도모하여 학교 정보화에 이바지할 수 있다. 이렇게 개발된 시스템이 현장에서 활용되면서 나타난 교육적 효과 및 문제점을 분석하여 해결 방안을 제시하는 것은 시스템의 개발 못지않게 중요하다고 할 수 있다. 따라서 본 연구에서는 첫째, 본 시스템 개발을 위한 ICT 활용 교수·학습 과정안 형태의 구안과정과 둘째, 본 시스템의 설계와 구현 방법의 개요, 그리고 셋째, 초등학교 현장에서 적용하면서 나타난 시스템의 효과와 문제점 분석 및 개선방안을 제시하였다 또 연구를 통하여 초등교육에서 사용하게 될 전자 교육 시스템의 개발 과정 및 활용 상의 고려사항과 문제점의 해결 방안에 대한 교육적 근거를 제공하였다. The researchers developed On-line Lesson Planner System so that teachers can make a lesson plan using ICT(Information & Communication Technology) on line. Developed On-line Lesson Planner System can make ICT using lesson plans store in the database, manage them systematically and help maximize share, use and storage of the lesson plans. It can contribute to the school informatization. It is important to suggest solution through analyzing the educational effects and problems appeared during applying to this developed system in real fields. Thus, this study suggests first, procedure of designing the lesson plan using ICT for the development of this system, second, the summary of designing and embodying methods, and third, the improvement and analysis of the effects and problems revealed in elementary school fields. This study provided educational grounds of the solution to the problems and consideration of this On-line Lesson Planner system.

가스크로마토그래피를 이용한 요중 마뇨산 측정시 새로운 시료 전처리 방법의 검증

조수현,임용현,김선민,권호장,하미나,한상환 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.1

Urinary hippuric acid was analyzed by gas chromatography/mass spectrometry method. A simple and economical derivatization procedure using excessive methanol in acidic condition was adopted to esterify hippuric acid. Quantitative analysis was performed with two internal standards, heptadecanoic acid and hydrocinnamic acid, to evaluate the derivatization procedure as an analytical method. Using the standard addition method, linear and reproducible calibration curves were obtained for both internal standards. Calibration experiment showed that good quantitative result could also be obtained with the calibration curve obtained without urine matrix. Recovery rates for the urine samples were in the range of 95.6∼111.4%. Using hydrocinnamic acid as internal standard, analysis time could be reduced.

보문 : 버섯 세균성갈색무늬병원균(Pseudomonas tolaasii)의 분비 독소(tolaasin)를 저해하는 미생물 Pseudomonas sp. HC1

이찬중 ( Chan Jung Lee ),유영미 ( Young Mi Yoo ),한주연 ( Ju Yeon Han ),전창성 ( Chang Sung Jhune ),정종천 ( Jong Chun Cheong ),문지원 ( Ji Won Moon ),서장선 ( Jang Sun Suh ),한혜수 ( Hye Su Han1 ),차재순 ( Jae Soon Cha ) 한국균학회 2013 韓國菌學會誌 Vol.41 No.4

A Gram-negative bacterium was isolated from mushroom media that markedly reduces the level of extracellular toxins (i.e., tolaasins) produced by Pseudomonas tolaasii, the most destructive pathogen of cultivated mushrooms. The HC1 strain was selected as detoxifying tolaasin by bioassay on potato and it was identified Pseudomonas sp. by the cultural, morphological and physiological characteristics, and analysis of the 16S rRNA.. The isolated bacterium is saprophytic but not parasitic nor pathogenic to cultivation mushroom. The isolated bacterium for P. tolaasii cell, was sufficient for detoxification in vitro. Inoculation of the isolated bacterium prevents the development of bacterial disease in Pleurotus ostreatus, Flammunia velutipes and Agaricus bisporus. Control efficacy of brown blotch of strain HC1 treatment was 69, 68 and 55% on Agaricus bisporus, Flammulina velutipes and Pleurotus ostreatus, respectively. The suppressive bacterium may be useful in future for the development of biocontrol system and the construction of genetically modified edible fungi resistant to the disease caused by P. tolaasii.

건강가정지원센터 가정생활교육 프로그램 운영 및 성과 : 용산구·숙명여자대학교 시범사업을 중심으로

김명자,계선자,박미석,장진경,김연화,한은주,류진아 한국가족관계학회 2005 한국가족관계학회지 Vol.10 No.1

The purpose of this study is to propose a model for service programs and management strategies for the division of family education in Healthy Families Center. For the purpose, the researchers find out demands for the family education programs of people in Yong-San Gu, Seoul, exam the effect of each family education program of Yong-San Gu & Sookmyung Women's University Healthy Families Center from June to December, 2004. According to the results, people in Yong-San Gu need economic education service mostly, and they want to study at Saturday afternoon. The programs show positive effect on the improvement of family health.