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      • KCI등재

        Follicular Proliferative Lesion Arising in Struma Ovarii

        박민지,민혜숙,김민아,신미경 대한병리학회 2015 Journal of Pathology and Translational Medicine Vol.49 No.3

        Malignant struma ovarii is extremely rare and difficult to diagnose histologically, particularly in cases of follicular carcinoma. This case study is intended to describe three cases of follicular proliferative lesion arising in struma ovarii that we experienced. The first case was clearly malignant given the clinical picture of multiple recurrences, but there was little histological evidence of malignancy. Our second case featured architectural and cellular atypia and necrosis and was diagnosed as malignant despite the absence of vascular and stromal invasion. Our third case exhibited solid microfollicular proliferation without any definite evidence of malignancy (even the molecular data was negative); however, we could not completely exclude malignant potential after conducting a literature review. In cases such as our third case, it has been previously suggested that a diagnostic term recognizing the low-grade malignant potential, such as “proliferative stromal ovarii” or “follicular proliferative lesion arising in the stromal ovarii” would be appropriate.

      • KCI등재

        Safety of red ginseng oil for single oral administration in SpragueeDawley rats

        박민지,김규봉,전미라,정우식 고려인삼학회 2014 Journal of Ginseng Research Vol.38 No.1

        The single oral administration of red ginseng oil (5000 mg/kg) to SpragueeDawley rats induced nochanges in behavioral patterns, clinical signs, and body weight, and hepatotoxicity parameters such asaspartate aminotransferase and alanine aminotransferase for 14 d. Therefore, these results suggest thatthe red ginseng oil is safe and nontoxic acutely.

      • ‘숙명역사관’뮤지엄 아이덴티티 개선을 위한 마케팅, 디자인 전략 수립 -특별 기획전, 홍보, 기프트 샵을 중심으로-

        박민지,박한빛,서예원,이진민,장미정,이성애 숙명여자대학교 산업디자인연구소 2017 숙명디자인학 연구 Vol.24 No.-

        본 연구는 디자인과 마케팅이 이분법적으로 나누어질 수 없음을 인식하고, 디자인과 마케팅을 융합하여 스페이스 디자인 마케팅을 통한 뮤지엄아이덴티티를 구축하는 일련의 프로세스를 제안하는데 목적이 있다. 본 연구는 2017년 3월~6월 총 15주간 숙명여자대학교 환경디자인과 ‘브랜드·스페이스·마케팅’수업에 서 진행된 결과물로서 작업물을 정리하였다. 본 연구의 범위는 4개(物, 事, 人, 場)의 주제 중, 장소(場)를 중심으로 ‘숙명역사관’의 그래픽, 제품, 공간을 개발하는 브랜드 매뉴얼과 연관하여 한정한다. 이에 본 연구는 ‘숙명역사관’이 가지고 있는 역사적 컨텐츠와 가치를 통해 현재 상황과 문제점을 분석하였다. 그 결과 ‘숙명역사관’의 다양한 마케팅 전략을 제시하고 이에 따른 디자인 전략과 해결 방안을 통해 디자인과 마케팅의 융합을 꾀하였다. 아울러 SWOT 분석을 통해 로고, 명함부터 새로 기획하는 숙명역사관 기프트샵, 인테리어디자인, 디스플레이, 공간연출과 그 안의 제품디자인에 이르기까지 일관성과 통일성을 추구했다. 끝으로 본 연구는 뮤지엄아이덴티티 구축을 위한 창의적 디자인 프로세스를 고찰하며, 이를 바탕으로 개발 매뉴얼을 총체적으로 정리함에 있어서 뮤지엄 브랜딩의 기초 자료로 활용될 것으로 기대된다.

      • KCI등재후보

        일개 임상시험에서 피험자 순응도에 영향을 미치는 요인 분석

        박민지,나현오,김영인,김경수 대한임상약리학회 2009 Translational and Clinical Pharmacology Vol.17 No.1

        Background: Due to the strong relationship between successful clinical trial result and subject's high compliance to protocol, this research aimed to provide the basic information of the key factors affecting subject's compliances to improve the quality of the clinical trial . Method: The cross sectional study was retrospectively investigated with the result of the phase III clinical trial which had been conducted with co-participation of investigators belonged to two different medical specialties involving 15 university affiliated hospitals from October 2007 to April 2009. The factors were classified into subject factor, institution factor, principal investigator factor, study staff factor and clinical research associate (CRA) factor. The collected data was tested at significance level of 5% using SAS program (Version 8.0). To investigate the correlation between subject's compliance and the suggested factors, chi-square test and multiple logistic regression analysis were tested. Specifically, stepwise multiple regression analysis was conducted to analyze the factors affecting the final subject's compliances. The data for nine subjects from two institutions which had made poor progress during the trial was excluded from the analysis. Result: Among subject's compliances, the factors affecting the visit completion and medication compliance were come out differently. In terms of the visit completion, as a result of stepwise multiple regression analysis, the rate of visit completion was 4.9 times higher in the group of subjects taking corticosteroids than others, which is significant. In addition, the rate of visit completion was 10 times and 6.5 times respectively higher with principal investigators and clinical research coordinators belonging to the department in charge of the subject enrollment with subject's underlying disease treatment than the department in charge of the tests during the clinical trial, which is significant. Particularly, in terms of medication compliance 80% of investigational product medication compliance was shown in the group of no CRA change which is 4.0007 times significantly higher than others. Conclusion: Among subject's compliances, the significantly high influential factor for the visit completion was the subjects taking corticosteroids which were one of the risk factor for peptic ulcer and the specialty factor in charge of the continuous treatment for subjects and its principal investigator. Also, the factor which had significantly highly affected subject's medication compliance was CRA factor. Since subject's compliances were limited with the visit completion and medication compliance in this study, further investigations about subject's compliance are required. Also, it will be necessary to investigate CRA's indirect influence to subject's medication compliance in detail in the future. Background: Due to the strong relationship between successful clinical trial result and subject's high compliance to protocol, this research aimed to provide the basic information of the key factors affecting subject's compliances to improve the quality of the clinical trial . Method: The cross sectional study was retrospectively investigated with the result of the phase III clinical trial which had been conducted with co-participation of investigators belonged to two different medical specialties involving 15 university affiliated hospitals from October 2007 to April 2009. The factors were classified into subject factor, institution factor, principal investigator factor, study staff factor and clinical research associate (CRA) factor. The collected data was tested at significance level of 5% using SAS program (Version 8.0). To investigate the correlation between subject's compliance and the suggested factors, chi-square test and multiple logistic regression analysis were tested. Specifically, stepwise multiple regression analysis was conducted to analyze the factors affecting the final subject's compliances. The data for nine subjects from two institutions which had made poor progress during the trial was excluded from the analysis. Result: Among subject's compliances, the factors affecting the visit completion and medication compliance were come out differently. In terms of the visit completion, as a result of stepwise multiple regression analysis, the rate of visit completion was 4.9 times higher in the group of subjects taking corticosteroids than others, which is significant. In addition, the rate of visit completion was 10 times and 6.5 times respectively higher with principal investigators and clinical research coordinators belonging to the department in charge of the subject enrollment with subject's underlying disease treatment than the department in charge of the tests during the clinical trial, which is significant. Particularly, in terms of medication compliance 80% of investigational product medication compliance was shown in the group of no CRA change which is 4.0007 times significantly higher than others. Conclusion: Among subject's compliances, the significantly high influential factor for the visit completion was the subjects taking corticosteroids which were one of the risk factor for peptic ulcer and the specialty factor in charge of the continuous treatment for subjects and its principal investigator. Also, the factor which had significantly highly affected subject's medication compliance was CRA factor. Since subject's compliances were limited with the visit completion and medication compliance in this study, further investigations about subject's compliance are required. Also, it will be necessary to investigate CRA's indirect influence to subject's medication compliance in detail in the future.

      • 청각장애학생의 장애정체성과직업선호도의 상관성 연구

        박민지 한국청각언어장애교육학회 2010 한국청각·언어장애교육연구 Vol.1 No.1

        '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

        Self-actualization is recognized as an individual's loyal role in order to form identity in the middle of relationship with oneself and family, society, and nation. Job can be seen to be performance of a role in society. In order for people with hearing impairments, who have difficulty in light of communication, to be successfully adjusted to work life, the positive ego-identity is very important. In other words, ego-identity is a major factor of having influence upon self-actualization and job preference. Desirable work life comes to decide on quality of life. Consequently, ego-identity, self-actualization and work life can be known to be formed with complementary relationship of deciding on a human being's life. This study aims to analyze relationship between identity and job preference in students with hearing impairments, and to offer basic data for career education. Its specific objective is as follows. First, it surveys disability identity in students with hearing impairments. Second, it surveys job preference in students with hearing impairments. Third, it analyzes relationship between disability identity and job preference in students with hearing impairments. The results, which were obtained through this study, are as follows. First, the disability identity according to individual background variable in students with hearing impairments showed significant difference depending on whether the parents in students with hearing impairments are normal parents or parents with hearing impairments. The disability identity in case of normal parents was indicated to be higher than disability identity in case of parents with hearing impairments. Second, the job preference according to individual background variable in students with hearing impairments showed significant difference depending on whether students with hearing impairments wear protector. In case of being performed cochlear implant, the job preference was the highest. The next was followed by a case of wearing hearing aid. The group that showed the lowest job preference was the one that didn't wear protector. Finally, the correlation between job preference and disability identity was not related. Therefore this study concluded that the identity of the hearing impaired is not important factor to select the job preference. 이 연구는 청각장애학생의 정체성과 직업 선호도 사이의 관계를 분석하고 진로교육을 위한 기초 자료를 제공하기 위하여 5개 청각장애 특수학교에 재학하고 있는 고등학교 학생을 대상으로 설문조사를 실시하였다. 분석한 결과 첫째, 건청 부모인 경우의 장애정체감이 청각장애 부모인 경우의 장애정체감보다 높게 나타났다. 둘째, 학생이 인공와우 수술을 한 경우 직업선호도가 가장 높았고, 다음이 보청기를 착용한 경우, 그리고 가장 낮은 직업선호도를 보인 집단은 보장구를 착용하지 않은 집단으로 나타났다. 셋째, 직업선호도와 장애정체성의 상관성은 없다. 즉 직업선호도와 장애정체성에 대한 단편적 분석에 있어서는 청각장애 학생의 배경변인별에 따라서 독특한 선택을 하는 경우도 있으나, 청각장애 학생의 정체성이 직업선호도에 미치는 영향은 없음을 알 수 있었다. 이 연구를 토대로 청각장애학생 당사자가 손상으로서의 외적조건보다 소질과 흥미로서의 내적조건이 보다 가치 있음을 알게 하여 직업은 삶을 위한 수단이 아닌 삶의 일부이자 목적이 되고 있음을 인식시키고자 한다.

      • KCI등재

        하악 제2소구치 결손과 연관된 치아 결손 및 발육지연

        박민지,김성오,송제선,이제호 대한소아치과학회 2018 大韓小兒齒科學會誌 Vol.45 No.4

        선천적 치아의 결손은 비교적 흔한 치아 발육장애이며 하악 제2소구치의 결손은 치아 결손 중 가장 많이 나타나는 것으로 알려져있다. 이 연구의 목적은 하악 제2소구치 결손과 연관되어 나타나는 다른 치아의 결손 및 치아의 발육 지연에 대해 조사하는 것이다. 이 연구는 2014년부터 2016년까지 연세대학교 치과대학을 내원하여 파노라마 방사선을 찍은 만 9세-15세의 소아청소년 중 하악제2소구치 결손이 있는 환자를 대상으로 시행되었다. 하악 제2소구치의 결손을 가진 125명의 환자들 중 다른 치아의 결손은 58명(46.4%)에서 나타났으며 발육이 지연된 치아는 38명(30.4%)에서 나타났다. 이번 연구에서 하악 제2소구치의 결손을 가진 환자는 그렇지 않은 어린이와 비교하였을 때 치아 결손 및 치아 발육지연의 유병률이 높게 나타났다. Tooth agenesis is a common human dental anomaly and the agenesis of mandibular second premolars has been proven to be the most frequently observed. The aim of this study is to investigate tooth agenesis and delayed tooth development in patients with agenesis of mandibular second premolars. This study reviewed 9 to 15 year-old patients with agenesis of mandibular second premolars who visited the department of pediatric dentistry of Yonsei University Dental Hospital and took panoramic radiographs from January 2014 to December 2016. On panoramic radiographs, agenesis of teeth was observed and developmental delay of teeth was evaluated by the Nolla method. Among 125 patients with agenesis of mandibular second premolars, 58 patients (46.4%) showed agenesis of other teeth and 38 patients (30.4%) showed delayed tooth development. In this study, patients with agenesis of mandibular second premolars were more likely to have tooth agenesis or delayed eruption of other teeth.

      • KCI등재

        소비자의 혜택 및 위험 지각이 중고유아용품 구매의도에 미치는 영향과 소비가치와 사회규범의 조절효과

        박민지,손상희 한국소비자정책교육학회 2015 소비자정책교육연구 Vol.11 No.4

        본 연구는 소비자들의 중고유아용품에 대한 인식과 구매의도는 어떠한지, 영향을 미치는 요인이 무엇인지를 파 악하여 윤리적 소비문화를 정착시키고 중고제품 구매와 사용이 국내에서 보다 더 활성화되는데 기여하는 것을 목 적으로 한다. 이에 0-5세 자녀를 둔 여성(출산 예정자 포함)을 조사 대상자로 선정하였고, 총 532명의 조사결과 가 분석에 사용되었다. 주요 연구결과는 다음과 같다. 첫째, 중고유아용품에 대한 소비자의 혜택 지각은 ‘경제적 혜택’이 7점 만점에서 5.24, ‘심리사회적 혜택’이 4.60으로 모두 긍정적 평가를 하는 것으로 나타났다. 위험 지각에서는 ‘거래 위험’이 4.74로 가장 높게 나타났으며, 그 다음으로는 ‘제품 위험’, ‘심리사회적 위험’ 순으로 나타났다. 둘째, 중고유아용 품에 대한 혜택 및 위험 지각이 구매의도에 미치는 영향에 있어서는 경제적 혜택과 제품 위험 지각이 중고 유모차, 유아복, 책/장난감/교구 구매의도 모두에 유의한 영향을 미치는 것으로 나타났다. 심리사회적 혜택은 유아용품 종류에 따라 부분적으로 유의한 영향을 미쳤다. 셋째, 중고유아용품 구매의도에 대한 소비가치와 사회규범의 조절 효과를 살펴본 결과, 소비가치와 사회규범은 유아용품 종류에 따라 부분적으로 조절효과가 있는 것으로 나타났다. This study researched consumers’ awareness and purchasing intention about secondhand baby products and found what factors are influencing on purchasing secondhand baby products. The goal is to settle the ethical consumption culture and activate secondhand products purchase in our country. In this study, women with children 0 to 5 years old(including prospective birth) were selected as research subjects and 532 samples were used for analysis. The main conclusions of this study are as follows. First, based on the 7-point scale, the average of the ‘Economical benefit’ was 5.24 and the ‘Psychosocial benefit’ was 4.60 in the consumer benefit perception about secondhand baby products. Both showed that a positive evaluation. In the risk perception, the average of the ‘Transaction risk’ was the highest with 4.74 and the next was ‘Product risk’, the last was ‘Psychosocial risk’. Second, In the effect of benefit and risk perception about secondhand baby products on purchasing intention, ‘Economical benefit’ and ‘Product risk’ had significant influence on the secondhand stroller, baby clothing, books/toys/education tools purchasing intention. ‘Psychosocial benefit’ affect partially depending on the type of baby products. Third, as a result of moderating effect of consumption values and social norms about secondhand baby products, consumption values and social norms had moderating effect partially depending on the type of baby products.

      • KCI등재

        청소년의 학교적응 변화에 따른 잠재계층분류와 내재화 문제 및 부모 방임의 영향력 분석

        박민지,유미숙 한국청소년시설환경학회 2020 청소년시설환경 Vol.18 No.3

        The purpose of this study is to investigate potential groups of youths' school adaptation change patterns and to examine the effects of parental neglect and adolescents' internalization problems (depression, social withdrawal). The Korean Youth Panel Survey (2,378 people), a 4th cohort, was used for analysis, and 5 years of data were used for analysis. They were analyzed by Latent Class Growth Analysis(LCGA), Growth Mixture Model(GMM), Logistic Regression. As a result of the study, first, it was found that school adaptation increased over time and after then decreased.. Second, the two potential characteristics of the school adaptation variable were identified as a'unchanged group' that does not change over time and a'adapted increase group' that changes negatively over time. Third, depression did not significantly affect the potential class, and social withdrawal and parental neglect were identified as factors affecting school adaptation. 본 연구의 목적은 청소년 학교 적응 변화 양상의 잠재적인 집단을 조사하고 부모의 방임과 청소년의 내면화 문제(우울, 사회적 위축)의 영향을 조사하는 것이다. 이를 위해 한국아동·청소년패널 데이터(Korean Children & Youth Panel Survey)의 초4 코호트인 2,378명을 분석에 사용하였으며, 5년치 자료를 분석에 활용하였다. 분석 방법은 첫 번째로 잠재성장모형 분석을 실시하고, 두 번째로 개체 간 질성을 규명하기 위하여 성장혼합 모델(Growth Mixture Model)을 적용하였다. 마지막으로 분류된 잠재계층을 중심으로 개체 간 효과(between effect)를 분석하기 위하여 로지스틱 회귀분석(logistic regression)을 실시하였다. 연구 결과, 먼저 학교 적응 변인의 단일계층 잠재성장 모형 추정 결과 학교 적응이 시간이 지남에 따라 증가하고 그 후에 감소한 것으로 나타났다. 둘째, 학교 적응 변수의 두 가지 잠재적 특성은 시간이 지나도 안정적인 '무변화집단'과 시간이 지남에 따라 부정적으로 변화하는 '부적응증가집단'으로 확인되었다. 셋째, 우울증은 잠재적 계급에 큰 영향을 미치지 않았으며 사회적 위축과 부모의 방임이 학교 적응에 영향을 미치는 요인으로 확인되었다.

      • KCI등재

        전자감독제도의 예방적 경찰활동으로서의 함의 - 범죄징후 예측시스템의 허용성을 중심으로 -

        박민지,서정범 고려대학교 법학연구원 2020 고려법학 Vol.0 No.99

        The GPS-based electronic monitoring was introduced and operated in Korea in 2008 to curb repeat offenses of sexual crime offenders or violent criminals belonging to high-risk groups. In the early days of the system's introduction, the monitoring was a follow-up system that could only determine whether the electronic tagging was worn, prohibited from entering or leaving the country, or violated the victims' access conditions. However, from February 2019, the Ministry of Justice developed the electronic monitoring into a pre-preventive system, or so-called ‘Criminal sign predictive system' that analyzes and prevents risks to crimes in advance by utilizing big data, breaking away from the existing simple reactive system. Furthermore, the Ministry of Justice proposes a long-term development vision to operate the crime sign prediction system in a more advanced state through the introduction of so-called "external information-sensitive electronic tagging" in the future. The need for this introduction of the Criminal Sign Prediction System, part of a plan to conduct probation using a highly developed electronic supervisory system for high-risk offenders with high recidivism, can easily be recognized as a suitable means to prevent potential risks to the safety of the general public. However, this researcher thinks that practical applicability or acceptability is a separate matter from the need for introduction, requiring a review from a public law perspective. In other words, it is necessary to consider the question of where to find the legal basis for the introduction of a system for predicting crime signs, and - even assuming the existence of a legal basis - whether specific means comply with requests for proportional principles. Based on recognizing these problems, this researcher would like to address the study's subject, a problem from a public law point of view with the criminal sign predictive system. 재범가능성이 높은 성범죄자 또는 고위험군에 속하는 폭력범죄자의 재범을 억제하기 위하여 GPS 기반의 전자감독제도가 2008년 국내에 도입되어 운영되어 오고 있다. 제도의 도입 초기 동 제도는 전자발찌 착용상태나 출입금지 또는 외출제한 명령, 피해자 접근금지 명령 등의 준수사항 위반 여부만을 파악할 수 있는 사후대응적 시스템이었다. 그러나 2019년 2월부터 전자감독제도는 기존의 단순한 사후대응적 시스템에서 탈피하여 빅데이터를 활용하여 범죄에 대한 위험을 사전에 분석하여 예방하는 사전예방적 시스템, 즉 이른바 ‘범죄징후 예측시스템’으로 발전하기에 이르렀다. 그리고 법무부는 향후 이른바 ‘외부정보감응형 전자발찌’등의 도입을 통하여 범죄징후 예측시스템을 보다 고도로 발전된 상태로 운영하려고 하는 장기발전 비전을 제시하고 있다. 재범가능성이 높은 고위험군 범죄자들에 대해 고도로 발전된 전자감독제도를 활용하여 보호관찰을 행하는 방안의 일환인 범죄징후 예측시스템은 일반 공중의 안전에 대한 잠재적인 위험을 방지하기에 적합한 수단으로 그의 도입 필요성은 쉽게 인정될 수 있다. 그러나 현실적인 도입가능성 내지 허용성의 문제는 도입 필요성과는 차원을 달리하는 별개의 문제로서 공법적 관점에서 재검토를 요한다고 생각한다. 즉, 범죄징후 예측시스템 도입의 법적 근거를 어디에서 찾을 것인가의 문제, 그리고 - 법적 근거의 존재를 전제하는 경우에도 - 구체적 수단이 비례의 원칙의 요청을 준수하는 것인지의 문제에 대한 고찰이 필요하다. 이에 본 연구자는 이러한 문제점에 대한 인식을 토대로 범죄징후 예측시스템에 관한 공법적 문제라는 연구주제에 관하여 다뤄보고자 한다.

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